BacMap

Definition	Burkholderia xenovorans LB400 chromosome 1, complete sequence.
Accession	NC_007951
Length	4,895,836

Click here to switch to the map view.

The map label for this gene is phbB [H]

Identifier: 91783475

GI number: 91783475

Start: 2320439

End: 2321179

Strand: Direct

Name: phbB [H]

Synonym: Bxe_A2341

Alternate gene names: 91783475

Gene position: 2320439-2321179 (Clockwise)

Preceding gene: 91783474

Following gene: 91783476

Centisome position: 47.4

GC content: 61.0

Gene sequence:

>741_bases
ATGACACAGCGAATTGCGTACGTAACGGGCGGGATGGGCGGCATCGGCACGAGCATTTGCCAGCGGCTGCATAAAGAGGG
CTTCAAGGTCGTCGCAGGCTGCGGCCCGAACTCGCCGCGCCGGGTGAAGTGGCTCGACGAGCAGAAGGCGCTGGGCTTCG
ATTTCATCGCGTCCGAAGGCAACGTCGGTGACTGGGAGTCGACGAGGAGCGCGTTCGACAAGGTCAAGGCCGAAGTCGGA
GAGATCGACGTGCTGGTGAACAACGCCGGCATTACGCGCGACGTCGTGTTCCGCAAGATGACGCACGAAGACTGGACAGC
GGTGATCGACACCAACCTGACCAGCCTCTTCAACGTCACCAAGCAGGTGATCGACGGCATGGTCGAGCGCGGCTTTGGCC
GTATCATCAACATTTCGTCGGTGAATGGGCAGAAGGGCCAGTTCGGCCAGACCAACTACTCGACCGCGAAGGCCGGCATT
CACGGCTTCACGATGTCGCTGGCGCAGGAAGTGGCCACCAAGGGCGTGACGGTCAACACCGTTTCTCCCGGCTACATCGG
CACCGACATGGTCAAATCGATCCGCCCCGACGTGCTGGAAAAGATCATTGCTACGATTCCGGTGCGCCGCCTTGGCCAGC
CGCAGGAAATCGGCTCGATCGTGGCGTGGCTGGCATCGGAAGAATCGGGTTTCGCCACAGGCGCTGATTTTTCGCTGAAC
GGCGGTTTGCATATGGGCTGA

Upstream 100 bases:

>100_bases
TGGCCTCGTCGGCCGGTCGCCCGGCGGCTGCGGAGATGAAGCACAGACGAGGGAAGAGGCGGCCGTTCGGCGCCTCGAAA
ACGATAACGGAGTGTAGTTT

Downstream 100 bases:

>100_bases
GTCACAGGCGCGCCGCTCACGAGGCAGCGCGCTTCGGCTCAGATGGTTCGGCGGCGTCCCGATTGCGCAATGGCCAGATT
GCGCAGCCGGCAGGACGCCG

Product: acetyacetyl-CoA reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MTQRIAYVTGGMGGIGTSICQRLHKEGFKVVAGCGPNSPRRVKWLDEQKALGFDFIASEGNVGDWESTRSAFDKVKAEVG
EIDVLVNNAGITRDVVFRKMTHEDWTAVIDTNLTSLFNVTKQVIDGMVERGFGRIINISSVNGQKGQFGQTNYSTAKAGI
HGFTMSLAQEVATKGVTVNTVSPGYIGTDMVKSIRPDVLEKIIATIPVRRLGQPQEIGSIVAWLASEESGFATGADFSLN
GGLHMG

Sequences:

>Translated_246_residues
MTQRIAYVTGGMGGIGTSICQRLHKEGFKVVAGCGPNSPRRVKWLDEQKALGFDFIASEGNVGDWESTRSAFDKVKAEVG
EIDVLVNNAGITRDVVFRKMTHEDWTAVIDTNLTSLFNVTKQVIDGMVERGFGRIINISSVNGQKGQFGQTNYSTAKAGI
HGFTMSLAQEVATKGVTVNTVSPGYIGTDMVKSIRPDVLEKIIATIPVRRLGQPQEIGSIVAWLASEESGFATGADFSLN
GGLHMG
>Mature_245_residues
TQRIAYVTGGMGGIGTSICQRLHKEGFKVVAGCGPNSPRRVKWLDEQKALGFDFIASEGNVGDWESTRSAFDKVKAEVGE
IDVLVNNAGITRDVVFRKMTHEDWTAVIDTNLTSLFNVTKQVIDGMVERGFGRIINISSVNGQKGQFGQTNYSTAKAGIH
GFTMSLAQEVATKGVTVNTVSPGYIGTDMVKSIRPDVLEKIIATIPVRRLGQPQEIGSIVAWLASEESGFATGADFSLNG
GLHMG

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=253, Percent_Identity=36.3636363636364, Blast_Score=148, Evalue=4e-36,
Organism=Homo sapiens, GI40254992, Length=246, Percent_Identity=32.1138211382114, Blast_Score=131, Evalue=7e-31,
Organism=Homo sapiens, GI4758504, Length=254, Percent_Identity=32.6771653543307, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI4504505, Length=234, Percent_Identity=32.4786324786325, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI32483357, Length=249, Percent_Identity=29.3172690763052, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI7705925, Length=245, Percent_Identity=28.5714285714286, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI19923817, Length=253, Percent_Identity=30.4347826086957, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI83715985, Length=254, Percent_Identity=31.1023622047244, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI10190704, Length=247, Percent_Identity=27.5303643724696, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI126723750, Length=255, Percent_Identity=28.2352941176471, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI109715829, Length=239, Percent_Identity=26.7782426778243, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI59889578, Length=208, Percent_Identity=29.8076923076923, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI5031737, Length=248, Percent_Identity=27.4193548387097, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI66933014, Length=187, Percent_Identity=28.8770053475936, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI7705855, Length=209, Percent_Identity=33.4928229665072, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI31542939, Length=206, Percent_Identity=31.5533980582524, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI40548397, Length=213, Percent_Identity=29.5774647887324, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI214010158, Length=213, Percent_Identity=29.5774647887324, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI214010156, Length=213, Percent_Identity=29.5774647887324, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI22758144, Length=213, Percent_Identity=29.5774647887324, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI7706318, Length=202, Percent_Identity=27.7227722772277, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI150247226, Length=191, Percent_Identity=29.8429319371728, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI33667109, Length=200, Percent_Identity=30.5, Blast_Score=74, Evalue=8e-14,
Organism=Homo sapiens, GI22507405, Length=187, Percent_Identity=28.8770053475936, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI44680136, Length=187, Percent_Identity=32.0855614973262, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI44680133, Length=187, Percent_Identity=32.0855614973262, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI17738292, Length=187, Percent_Identity=32.0855614973262, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI19743808, Length=193, Percent_Identity=29.0155440414508, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI7657478, Length=189, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI4503817, Length=184, Percent_Identity=28.2608695652174, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI20149619, Length=207, Percent_Identity=26.5700483091787, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI126723191, Length=186, Percent_Identity=27.4193548387097, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1787335, Length=248, Percent_Identity=43.1451612903226, Blast_Score=202, Evalue=1e-53,
Organism=Escherichia coli, GI87082100, Length=251, Percent_Identity=37.8486055776892, Blast_Score=151, Evalue=4e-38,
Organism=Escherichia coli, GI1790717, Length=240, Percent_Identity=31.25, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1789208, Length=242, Percent_Identity=29.3388429752066, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1788459, Length=244, Percent_Identity=29.5081967213115, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI2367175, Length=248, Percent_Identity=30.6451612903226, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI87082160, Length=245, Percent_Identity=28.5714285714286, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1787905, Length=240, Percent_Identity=29.1666666666667, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787820, Length=193, Percent_Identity=33.6787564766839, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI2367365, Length=248, Percent_Identity=30.241935483871, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789378, Length=252, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1786812, Length=250, Percent_Identity=27.6, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1789057, Length=259, Percent_Identity=27.4131274131274, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1786701, Length=193, Percent_Identity=24.8704663212435, Blast_Score=61, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=247, Percent_Identity=40.080971659919, Blast_Score=163, Evalue=7e-41,
Organism=Caenorhabditis elegans, GI17555706, Length=246, Percent_Identity=36.1788617886179, Blast_Score=158, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI17538182, Length=254, Percent_Identity=33.8582677165354, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17560676, Length=251, Percent_Identity=31.0756972111554, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17568967, Length=247, Percent_Identity=33.1983805668016, Blast_Score=107, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI71994600, Length=247, Percent_Identity=28.7449392712551, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI115534694, Length=245, Percent_Identity=28.1632653061224, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17561402, Length=252, Percent_Identity=29.7619047619048, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71994604, Length=251, Percent_Identity=27.8884462151394, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI193203115, Length=189, Percent_Identity=32.2751322751323, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI193203117, Length=189, Percent_Identity=32.2751322751323, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562910, Length=264, Percent_Identity=29.9242424242424, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17559104, Length=262, Percent_Identity=27.8625954198473, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17536651, Length=252, Percent_Identity=28.1746031746032, Blast_Score=78, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17561272, Length=189, Percent_Identity=27.5132275132275, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI193204405, Length=268, Percent_Identity=27.2388059701493, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17508651, Length=250, Percent_Identity=26.4, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17560332, Length=272, Percent_Identity=29.4117647058824, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17536025, Length=251, Percent_Identity=27.4900398406374, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17562906, Length=264, Percent_Identity=28.7878787878788, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17538486, Length=269, Percent_Identity=26.3940520446097, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17560150, Length=255, Percent_Identity=28.6274509803922, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17562990, Length=256, Percent_Identity=27.34375, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=269, Percent_Identity=26.3940520446097, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17544670, Length=263, Percent_Identity=24.7148288973384, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17531453, Length=276, Percent_Identity=26.8115942028986, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17562904, Length=251, Percent_Identity=27.4900398406374, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=268, Percent_Identity=27.2388059701493, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560220, Length=264, Percent_Identity=27.6515151515151, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17538480, Length=265, Percent_Identity=26.4150943396226, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17565030, Length=265, Percent_Identity=26.4150943396226, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI72000259, Length=196, Percent_Identity=28.0612244897959, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17564282, Length=133, Percent_Identity=28.5714285714286, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=248, Percent_Identity=33.0645161290323, Blast_Score=112, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6324126, Length=255, Percent_Identity=27.4509803921569, Blast_Score=83, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6323882, Length=201, Percent_Identity=26.3681592039801, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24639444, Length=246, Percent_Identity=35.3658536585366, Blast_Score=139, Evalue=2e-33,
Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=33.4661354581673, Blast_Score=114, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24644339, Length=252, Percent_Identity=30.1587301587302, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI21357041, Length=253, Percent_Identity=31.6205533596838, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI28571526, Length=248, Percent_Identity=31.8548387096774, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24643142, Length=244, Percent_Identity=29.0983606557377, Blast_Score=101, Evalue=4e-22,
Organism=Drosophila melanogaster, GI18859837, Length=236, Percent_Identity=32.2033898305085, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21355319, Length=247, Percent_Identity=27.1255060728745, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI17737361, Length=257, Percent_Identity=30.3501945525292, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24644337, Length=169, Percent_Identity=33.7278106508876, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI21358495, Length=196, Percent_Identity=29.0816326530612, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24641232, Length=216, Percent_Identity=30.5555555555556, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24581726, Length=177, Percent_Identity=26.5536723163842, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24641388, Length=205, Percent_Identity=32.1951219512195, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI281364494, Length=199, Percent_Identity=28.1407035175879, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI78706930, Length=217, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI78706928, Length=217, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI78706926, Length=217, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI78706924, Length=217, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI78706922, Length=217, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI116007236, Length=203, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24584748, Length=190, Percent_Identity=26.3157894736842, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011283
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.36 [H]

Molecular weight: Translated: 26442; Mature: 26311

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQRIAYVTGGMGGIGTSICQRLHKEGFKVVAGCGPNSPRRVKWLDEQKALGFDFIASEG
CCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCCCEEEECCHHHCCCEEEEECCC
NVGDWESTRSAFDKVKAEVGEIDVLVNNAGITRDVVFRKMTHEDWTAVIDTNLTSLFNVT
CCCCHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHCCCCHHEEHHCCHHHHHHHH
KQVIDGMVERGFGRIINISSVNGQKGQFGQTNYSTAKAGIHGFTMSLAQEVATKGVTVNT
HHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEC
VSPGYIGTDMVKSIRPDVLEKIIATIPVRRLGQPQEIGSIVAWLASEESGFATGADFSLN
CCCCCCCHHHHHHCCHHHHHHHHHHHCHHHCCCHHHHHHHHHHHHCCCCCCCCCCCEEEC
GGLHMG
CCCCCC
>Mature Secondary Structure 
TQRIAYVTGGMGGIGTSICQRLHKEGFKVVAGCGPNSPRRVKWLDEQKALGFDFIASEG
CCEEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCCCEEEECCHHHCCCEEEEECCC
NVGDWESTRSAFDKVKAEVGEIDVLVNNAGITRDVVFRKMTHEDWTAVIDTNLTSLFNVT
CCCCHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHCCCCHHEEHHCCHHHHHHHH
KQVIDGMVERGFGRIINISSVNGQKGQFGQTNYSTAKAGIHGFTMSLAQEVATKGVTVNT
HHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEC
VSPGYIGTDMVKSIRPDVLEKIIATIPVRRLGQPQEIGSIVAWLASEESGFATGADFSLN
CCCCCCCHHHHHHCCHHHHHHHHHHHCHHHCCCHHHHHHHHHHHHCCCCCCCCCCCEEEC
GGLHMG
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2670935 [H]