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The map label for this gene is cbl [H]

Identifier: 91783353

GI number: 91783353

Start: 2197290

End: 2198216

Strand: Direct

Name: cbl [H]

Synonym: Bxe_A2466

Alternate gene names: 91783353

Gene position: 2197290-2198216 (Clockwise)

Preceding gene: 91783352

Following gene: 91783355

Centisome position: 44.88

GC content: 62.68

Gene sequence:

>927_bases
ATGAATTTCCAGCAATTGCGCTTCGTGCGCGAAGCCGTACGTCAGAACATGAATCTGACCGAGGTGGCGAACGTGCTGTA
CACGTCGCAATCAGGCGTGTCCAAACAGATCAAGGATCTGGAGGACGAACTCGGCGTCGATATTTTCATCCGGCGCGGCA
AGCGTCTGACGGGCCTCACCGAGCCGGGCAAGGCGGTGCATCAGTTGATCGAGCGGATGCTGCTCGACGCCGAGAATCTA
CGCCGCGTCGCGCGCCAGTACGCCGATCAGGATAGCGGGCACCTCGTCGTGGCCACCACGCACACGCAGGCGCGCTACGC
GCTGCCAAAGGTGATCCGCCAGTTCACCGAGGTGTTCCCCAAGGTGCATCTGGCGCTGCGCCAGGGAAGCCCGCAACAGA
TCGCGCAGATGATCATCAACGGCGAAGCGGACATCGGCATCTCCACCGAAGCGCTCGACCGCTTCCCGGATATCGTCACG
TTCCCGTGCTATTCGTGGCATCACGTGGTGGTCGTGCCGAAGGGTCATCCGCTGGTGGGCCGGCCGAATCTGACGCTCGA
CGAGATCGCCGAATTCCCGATCGTCACGTACGACCAGGATTTCACGGGCCGCTCGCATATCGACCAGGCGTTCGCGAAAG
CGGGCGCGTTGCCCGACGTCGTGCTGACCGCGATCGACGCCGACGTGATCAAGACGTATGTCGAACTGGGCATGGGTATC
GGCGTGGTTGCGGCGATGGCCTACGACCCCAAGCGCGACACGGAACTGGTCGCGCTCGACACGCAGCATCTGTTCGAAGC
GAGCACGACGCGGGTCGGTTTGCGCAAGGGCGCGTTCCTGCGTGCTTACGCGTACCGGCTGATCGAGATGTTCGCGCCGC
AGTTGAACGAAGCGGATATCGCCGCGCAGTTGCGCGAAGCAGTCTGA

Upstream 100 bases:

>100_bases
GTGTTTCCGGCGCAATGAGCGCAGTGCGCTCAGGCGCGGCAGACCCGGTGTTTCAATCAAACTCAAATAGCTCGACTCTG
GACGAACCGGAGACATACAG

Downstream 100 bases:

>100_bases
CGGTTGCATTCGGGTGCGTTCGGGCGGTTGAAGGGCCATCAGTTTCTTGCGAGGGGAAGAAGGCGGCCCTGGCTAGATCC
TGATGGTTGAATCACGGAAC

Product: transcriptional regulator CysB-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MNFQQLRFVREAVRQNMNLTEVANVLYTSQSGVSKQIKDLEDELGVDIFIRRGKRLTGLTEPGKAVHQLIERMLLDAENL
RRVARQYADQDSGHLVVATTHTQARYALPKVIRQFTEVFPKVHLALRQGSPQQIAQMIINGEADIGISTEALDRFPDIVT
FPCYSWHHVVVVPKGHPLVGRPNLTLDEIAEFPIVTYDQDFTGRSHIDQAFAKAGALPDVVLTAIDADVIKTYVELGMGI
GVVAAMAYDPKRDTELVALDTQHLFEASTTRVGLRKGAFLRAYAYRLIEMFAPQLNEADIAAQLREAV

Sequences:

>Translated_308_residues
MNFQQLRFVREAVRQNMNLTEVANVLYTSQSGVSKQIKDLEDELGVDIFIRRGKRLTGLTEPGKAVHQLIERMLLDAENL
RRVARQYADQDSGHLVVATTHTQARYALPKVIRQFTEVFPKVHLALRQGSPQQIAQMIINGEADIGISTEALDRFPDIVT
FPCYSWHHVVVVPKGHPLVGRPNLTLDEIAEFPIVTYDQDFTGRSHIDQAFAKAGALPDVVLTAIDADVIKTYVELGMGI
GVVAAMAYDPKRDTELVALDTQHLFEASTTRVGLRKGAFLRAYAYRLIEMFAPQLNEADIAAQLREAV
>Mature_308_residues
MNFQQLRFVREAVRQNMNLTEVANVLYTSQSGVSKQIKDLEDELGVDIFIRRGKRLTGLTEPGKAVHQLIERMLLDAENL
RRVARQYADQDSGHLVVATTHTQARYALPKVIRQFTEVFPKVHLALRQGSPQQIAQMIINGEADIGISTEALDRFPDIVT
FPCYSWHHVVVVPKGHPLVGRPNLTLDEIAEFPIVTYDQDFTGRSHIDQAFAKAGALPDVVLTAIDADVIKTYVELGMGI
GVVAAMAYDPKRDTELVALDTQHLFEASTTRVGLRKGAFLRAYAYRLIEMFAPQLNEADIAAQLREAV

Specific function: May be an accessory regulatory protein within the cys regulon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788296, Length=307, Percent_Identity=54.3973941368078, Blast_Score=352, Evalue=1e-98,
Organism=Escherichia coli, GI1787530, Length=308, Percent_Identity=48.7012987012987, Blast_Score=313, Evalue=6e-87,
Organism=Escherichia coli, GI157672245, Length=225, Percent_Identity=30.6666666666667, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1788887, Length=250, Percent_Identity=29.6, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1790399, Length=260, Percent_Identity=25, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1788481, Length=244, Percent_Identity=25.8196721311475, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI2367136, Length=241, Percent_Identity=24.0663900414938, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI87082132, Length=122, Percent_Identity=33.6065573770492, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787806, Length=304, Percent_Identity=22.3684210526316, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1789204, Length=232, Percent_Identity=24.5689655172414, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790208, Length=224, Percent_Identity=25.8928571428571, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787601, Length=185, Percent_Identity=27.027027027027, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34421; Mature: 34421

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFQQLRFVREAVRQNMNLTEVANVLYTSQSGVSKQIKDLEDELGVDIFIRRGKRLTGLT
CCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCC
EPGKAVHQLIERMLLDAENLRRVARQYADQDSGHLVVATTHTQARYALPKVIRQFTEVFP
CCCHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHH
KVHLALRQGSPQQIAQMIINGEADIGISTEALDRFPDIVTFPCYSWHHVVVVPKGHPLVG
HHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHCCCCEEECCCCCEEEEEEECCCCCCC
RPNLTLDEIAEFPIVTYDQDFTGRSHIDQAFAKAGALPDVVLTAIDADVIKTYVELGMGI
CCCCCHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCH
GVVAAMAYDPKRDTELVALDTQHLFEASTTRVGLRKGAFLRAYAYRLIEMFAPQLNEADI
HHHHHHHCCCCCCCEEEEECHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHH
AAQLREAV
HHHHHHCC
>Mature Secondary Structure
MNFQQLRFVREAVRQNMNLTEVANVLYTSQSGVSKQIKDLEDELGVDIFIRRGKRLTGLT
CCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCC
EPGKAVHQLIERMLLDAENLRRVARQYADQDSGHLVVATTHTQARYALPKVIRQFTEVFP
CCCHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHH
KVHLALRQGSPQQIAQMIINGEADIGISTEALDRFPDIVTFPCYSWHHVVVVPKGHPLVG
HHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHCCCCEEECCCCCEEEEEEECCCCCCC
RPNLTLDEIAEFPIVTYDQDFTGRSHIDQAFAKAGALPDVVLTAIDADVIKTYVELGMGI
CCCCCHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCH
GVVAAMAYDPKRDTELVALDTQHLFEASTTRVGLRKGAFLRAYAYRLIEMFAPQLNEADI
HHHHHHHCCCCCCCEEEEECHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHH
AAQLREAV
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8529872; 9097040; 9278503 [H]