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The map label for this gene is lepB [H]

Identifier: 91783309

GI number: 91783309

Start: 2160630

End: 2161331

Strand: Direct

Name: lepB [H]

Synonym: Bxe_A2510

Alternate gene names: 91783309

Gene position: 2160630-2161331 (Clockwise)

Preceding gene: 91783308

Following gene: 91783316

Centisome position: 44.13

GC content: 63.25

Gene sequence:

>702_bases
ATGCGCATGCTCGGAAAACTCTGGCGCGACAACAAGAGCCTCGTCGCGTTCCTCTTCCTGATGGTGCTGTTTCGCAGTGC
CGTGGCCGACTGGAACGTCGTGCCGAGCGGCTCGATGCTGCCGACCATCCGTGAAGGCGACCGGATTTTCGTCGACAAGA
TGGCCTACGATCTGCGCGTGCCGCTCACGCATATCGCCATCGCGCATCTGCATGATCCGCAGCGCGGCGATATCGTGACG
ATCGATTCTTCGGCCGCGCATGAATTGATCGTCAAGCGTCTGATCGGTTTGCCCGGCGACAGCGTGGCGATGCGCGAGAA
CGTGTTGTACGTGAACGGCGTACGCGCCGATTACCAGCCGCTGAAATTCAAGCCGCTGCCCGGCGACGCGAGCTCACCCG
GCGATTATCTGACCGAGCGCTTCGATGGCATCGCGCATATCGTGCGGCTCGCGCCGCAAGCGCCAAGTCCGCGCGATTCG
TTCGGGCCGGTGATCGTGCCGCCCGGCGAGTATCTGATGCTCGGCGACAATCGTGACGACAGCGCCGATTCGCGTTACTT
CGGTTTCTTTTCGCGCAAGGAGCTGATGGGGCGCACGCGTCGCGTCGCGTATTCGCTCGACCCGGATCATTACTACGCGC
CGCGCTTCGAGCGCTTCGGCGCGCGGCTCGATAGTTCGGCGTCGGCGGTCGCGAGCCGCTAA

Upstream 100 bases:

>100_bases
TTGCTGCCGGCGGCGGTGGTACGATTTGCGCGGGCATGCTGCGAGAGAAAACGCCGCACATGCCACTGCTTTCGAATCCC
TTCCAATGGAGCCGCCTGCC

Downstream 100 bases:

>100_bases
AGCGGGCGCGGCCGGGCGTTCAGTGGCGCGACGGCAGCGCGAGGCGCCGTTCGTACCAGCGCTGCACGCTTTCGAGCATC
TGGCACAGCACCCAGTAGAC

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MRMLGKLWRDNKSLVAFLFLMVLFRSAVADWNVVPSGSMLPTIREGDRIFVDKMAYDLRVPLTHIAIAHLHDPQRGDIVT
IDSSAAHELIVKRLIGLPGDSVAMRENVLYVNGVRADYQPLKFKPLPGDASSPGDYLTERFDGIAHIVRLAPQAPSPRDS
FGPVIVPPGEYLMLGDNRDDSADSRYFGFFSRKELMGRTRRVAYSLDPDHYYAPRFERFGARLDSSASAVASR

Sequences:

>Translated_233_residues
MRMLGKLWRDNKSLVAFLFLMVLFRSAVADWNVVPSGSMLPTIREGDRIFVDKMAYDLRVPLTHIAIAHLHDPQRGDIVT
IDSSAAHELIVKRLIGLPGDSVAMRENVLYVNGVRADYQPLKFKPLPGDASSPGDYLTERFDGIAHIVRLAPQAPSPRDS
FGPVIVPPGEYLMLGDNRDDSADSRYFGFFSRKELMGRTRRVAYSLDPDHYYAPRFERFGARLDSSASAVASR
>Mature_233_residues
MRMLGKLWRDNKSLVAFLFLMVLFRSAVADWNVVPSGSMLPTIREGDRIFVDKMAYDLRVPLTHIAIAHLHDPQRGDIVT
IDSSAAHELIVKRLIGLPGDSVAMRENVLYVNGVRADYQPLKFKPLPGDASSPGDYLTERFDGIAHIVRLAPQAPSPRDS
FGPVIVPPGEYLMLGDNRDDSADSRYFGFFSRKELMGRTRRVAYSLDPDHYYAPRFERFGARLDSSASAVASR

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=257, Percent_Identity=30.7392996108949, Blast_Score=101, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056
- InterPro:   IPR019533
- InterPro:   IPR019766 [H]

Pfam domain/function: PF00717 Peptidase_S24; PF10502 Peptidase_S26 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 26111; Mature: 26111

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMLGKLWRDNKSLVAFLFLMVLFRSAVADWNVVPSGSMLPTIREGDRIFVDKMAYDLRV
CCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHCC
PLTHIAIAHLHDPQRGDIVTIDSSAAHELIVKRLIGLPGDSVAMRENVLYVNGVRADYQP
CHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHCCCCCCEEHHCCEEEEECCCCCCCC
LKFKPLPGDASSPGDYLTERFDGIAHIVRLAPQAPSPRDSFGPVIVPPGEYLMLGDNRDD
CEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCEEEEECCCCC
SADSRYFGFFSRKELMGRTRRVAYSLDPDHYYAPRFERFGARLDSSASAVASR
CCCCCCHHHHHHHHHHHHHHEEEEEECCCCCCCCCHHHHCCCCCCCHHHHHCC
>Mature Secondary Structure
MRMLGKLWRDNKSLVAFLFLMVLFRSAVADWNVVPSGSMLPTIREGDRIFVDKMAYDLRV
CCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHCC
PLTHIAIAHLHDPQRGDIVTIDSSAAHELIVKRLIGLPGDSVAMRENVLYVNGVRADYQP
CHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHCCCCCCEEHHCCEEEEECCCCCCCC
LKFKPLPGDASSPGDYLTERFDGIAHIVRLAPQAPSPRDSFGPVIVPPGEYLMLGDNRDD
CEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCEEEEECCCCC
SADSRYFGFFSRKELMGRTRRVAYSLDPDHYYAPRFERFGARLDSSASAVASR
CCCCCCHHHHHHHHHHHHHHEEEEEECCCCCCCCCHHHHCCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10993077 [H]