Click here to switch to the map view.

The map label for this gene is iciA [H]

Identifier: 91783137

GI number: 91783137

Start: 1983139

End: 1984071

Strand: Direct

Name: iciA [H]

Synonym: Bxe_A2670

Alternate gene names: 91783137

Gene position: 1983139-1984071 (Clockwise)

Preceding gene: 91783136

Following gene: 91783139

Centisome position: 40.51

GC content: 57.56

Gene sequence:

>933_bases
ATGATTTTCGACCGACAACAGTTGGAGGCGTTTGCCGCTGTCATTGATAAGCGCCATTTTGGAGAGGCCGCTGCGACGCT
GAATGTCACGCGCGGGGCCATTTCGCAGCGGCTCAAGGCATTGGAGGAAGCGATCGGGTCTCCGCTGGTGGTGCGAGACG
GAAATATCGCGACGCCAGCCGGAGAGGCATTATTACGACATATCCGAGCGCTCGAGGTACTGGAGGCTGATACTCTGCAG
CACATCAAGCCGACCGGTACGCCGAGGCCTCGCGTTGCCATCGCGGTCAATGCAGATTCGTTGGCAACATGGTTTGAGCC
GTGTGCCTGGGAAATCGCGAAGCGAAATGTCGCTTTGGAGCTCATCGTTGACGATCAGGATCACACCCTTCCGTCTCTGG
CACGAGGTGAGGCGATGGGTTGTGTATCAACCTCATCCGAACCTCCTACGGGATTTCGGGCCGAGAGTATCGGCACGATG
GAATACGAATGTGTTGCGACTGCGCAGTTCGCCCAACAGTATTTTTCGCAAGGGCTAGGCTTGCACAGCGTTCTTGGTGC
GCCCGCTGTACTCTACAACCGGAAGGACGGGCTGCATGCACTGTTTCTTGAGCGGCTGCTCGATTTCAAGGTGAAAGGTT
ACGCGACGCATTTCTTTCCGTCTCCGTCAGCGCTGCTGGCGGCAATCGAGAACGGTGTCGGGTATGGTCTGGTCCCCTGC
GTTCAGGCGCAACCGTTGATTGAAGCCGGCAAGCTTGTGAGTTTGGCTCCGGCGCACAAAGTCGCGGTCGATCTCTATTG
GCATCACTGGGAGACTGCGCCCTCGAACGCACAGGCGATCAGCGACCTTGTGATTCGCCATGCGCGTCAGGTGCTGATCC
AGTCTCCCCAACTGGTTGACCCGGCCGTTGACGAAGATACGTCGATCGTTTGA

Upstream 100 bases:

>100_bases
CTGTAGTGTGACCCGTGAACCGTCTTGGGCGGCACCCGGATGGCCAAGGCCAAGGGGGCACAAGCTACCAGCCCTCCTCA
GCAATGAAGTTGAGGTTCTC

Downstream 100 bases:

>100_bases
TTATCCTGATGAGTTCGGGTCCAGGGGCACAGAGCGCGTGCCGGTGGGTTTGGCCGTATTAATGGACGCTCTCGTTCGCA
AAGCCTCAACGAATGCGCAG

Product: chromosome replication initiation inhibitor protein

Products: NA

Alternate protein names: OriC replication inhibitor [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MIFDRQQLEAFAAVIDKRHFGEAAATLNVTRGAISQRLKALEEAIGSPLVVRDGNIATPAGEALLRHIRALEVLEADTLQ
HIKPTGTPRPRVAIAVNADSLATWFEPCAWEIAKRNVALELIVDDQDHTLPSLARGEAMGCVSTSSEPPTGFRAESIGTM
EYECVATAQFAQQYFSQGLGLHSVLGAPAVLYNRKDGLHALFLERLLDFKVKGYATHFFPSPSALLAAIENGVGYGLVPC
VQAQPLIEAGKLVSLAPAHKVAVDLYWHHWETAPSNAQAISDLVIRHARQVLIQSPQLVDPAVDEDTSIV

Sequences:

>Translated_310_residues
MIFDRQQLEAFAAVIDKRHFGEAAATLNVTRGAISQRLKALEEAIGSPLVVRDGNIATPAGEALLRHIRALEVLEADTLQ
HIKPTGTPRPRVAIAVNADSLATWFEPCAWEIAKRNVALELIVDDQDHTLPSLARGEAMGCVSTSSEPPTGFRAESIGTM
EYECVATAQFAQQYFSQGLGLHSVLGAPAVLYNRKDGLHALFLERLLDFKVKGYATHFFPSPSALLAAIENGVGYGLVPC
VQAQPLIEAGKLVSLAPAHKVAVDLYWHHWETAPSNAQAISDLVIRHARQVLIQSPQLVDPAVDEDTSIV
>Mature_310_residues
MIFDRQQLEAFAAVIDKRHFGEAAATLNVTRGAISQRLKALEEAIGSPLVVRDGNIATPAGEALLRHIRALEVLEADTLQ
HIKPTGTPRPRVAIAVNADSLATWFEPCAWEIAKRNVALELIVDDQDHTLPSLARGEAMGCVSTSSEPPTGFRAESIGTM
EYECVATAQFAQQYFSQGLGLHSVLGAPAVLYNRKDGLHALFLERLLDFKVKGYATHFFPSPSALLAAIENGVGYGLVPC
VQAQPLIEAGKLVSLAPAHKVAVDLYWHHWETAPSNAQAISDLVIRHARQVLIQSPQLVDPAVDEDTSIV

Specific function: Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789283, Length=293, Percent_Identity=32.4232081911263, Blast_Score=149, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR017685
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33564; Mature: 33564

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFDRQQLEAFAAVIDKRHFGEAAATLNVTRGAISQRLKALEEAIGSPLVVRDGNIATPA
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCH
GEALLRHIRALEVLEADTLQHIKPTGTPRPRVAIAVNADSLATWFEPCAWEIAKRNVALE
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCEEEE
LIVDDQDHTLPSLARGEAMGCVSTSSEPPTGFRAESIGTMEYECVATAQFAQQYFSQGLG
EEECCCCCCCCHHHCCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
LHSVLGAPAVLYNRKDGLHALFLERLLDFKVKGYATHFFPSPSALLAAIENGVGYGLVPC
HHHHHCCCCEEECCCCCHHHHHHHHHHCCHHCCEEEECCCCHHHHHHHHHCCCCCCCCCC
VQAQPLIEAGKLVSLAPAHKVAVDLYWHHWETAPSNAQAISDLVIRHARQVLIQSPQLVD
CCCCCHHHCCCEEEECCCHHEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
PAVDEDTSIV
CCCCCCCCCC
>Mature Secondary Structure
MIFDRQQLEAFAAVIDKRHFGEAAATLNVTRGAISQRLKALEEAIGSPLVVRDGNIATPA
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCH
GEALLRHIRALEVLEADTLQHIKPTGTPRPRVAIAVNADSLATWFEPCAWEIAKRNVALE
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCEEEE
LIVDDQDHTLPSLARGEAMGCVSTSSEPPTGFRAESIGTMEYECVATAQFAQQYFSQGLG
EEECCCCCCCCHHHCCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
LHSVLGAPAVLYNRKDGLHALFLERLLDFKVKGYATHFFPSPSALLAAIENGVGYGLVPC
HHHHHCCCCEEECCCCCHHHHHHHHHHCCHHCCEEEECCCCHHHHHHHHHCCCCCCCCCC
VQAQPLIEAGKLVSLAPAHKVAVDLYWHHWETAPSNAQAISDLVIRHARQVLIQSPQLVD
CCCCCHHHCCCEEEECCCHHEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
PAVDEDTSIV
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA