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The map label for this gene is qor [C]

Identifier: 91783122

GI number: 91783122

Start: 1971584

End: 1972597

Strand: Direct

Name: qor [C]

Synonym: Bxe_A2685

Alternate gene names: 91783122

Gene position: 1971584-1972597 (Clockwise)

Preceding gene: 91783121

Following gene: 161621318

Centisome position: 40.27

GC content: 64.5

Gene sequence:

>1014_bases
ATGAAAGCTATTGGTTACTACCGCAATTTGCCGGTCAGCGATCCGGAATCGCTGGTCGATCTGACCTTGCCCGAGCCGGT
GCCGGGCGAGCGCGACCTGCTGGTCGAAGTGCGGGCGGTGTCAGTCAATCCGGTCGACGTGAAGGTGCGCGCCGGCATGG
CGCCGGAAGCCGGTCAGCCGAAGGTGATCGGCTGGGATGCGGCTGGCGTCGTGCGCGCGGTCGGCAAGGGCGTCACGCTG
TTCAAGCCGGGCGACAAGGTCTGGTACGCCGGCTCGCTGCTGCGGGCGGGAACCAACAGCGAACTGCACGTCGTCGACGA
GCGGATCGTCGGGCAGATGCCACAGACGCTCGATTTCGCCGCCGCGGCTGCGTTGCCGCTGACGACGATTACCGCATGGG
AACTGCTGTTCGACCGTTTGAACGTGCCGGAAAGCGCGAAGCCGGGCGGCGCGACGCTGCTTGTGATCGGTGCGGCCGGC
GGCGTTGGTTCGATTCTCGTGCAACTCGCGCGCAAGCTGACCGGCCTCACGGTGATCGGCACCGCGTCGCGGCCGGAAAC
CACGCAGTGGGTCAGCGGTCTCGGCGCCCACCACGTGATCGACCATACGAAACCGCTGTCCGAAGAACTGAAGCGCATCG
GTTTCGATGGCGTCGACTACATCGCGAGCCTGAACCAGACGGACCATCACTTCGAGCAGATCGTCGCGTCGGTCAACCCG
CAGGGGCACATTGCGCTGATCGACGATCCCGAACTGTTCGACTTCCGCAAGCTGAAGACGAAGAGCGTGTCGCTGCACTG
GGAATTCATGTACACGCGCTCGATGTTCGCGACGCCCGACCAGATCCGTCAGCATGAACTGCTGAGCCGCGTCGCGTCGC
TGATCGACTCGGGTGTGCTGCGCACGACGCTGAACGAAACGTTCGGGACGATCAACGCCGCGAACCTGCGGCGCGCGCAC
GAACTGATCGAGACCAATCGCGCGCGCGGCAAGATCGTGCTTGAAGGGTTCTGA

Upstream 100 bases:

>100_bases
ATCATACGCACCAGTTGGGCAAGTTCCGGGCAGTAAGTATGTCGTCTGCTGTGGCTGGCTGCCCTGATGCGATCTTCCCG
TTCAAGCCTGGAGTGCAACG

Downstream 100 bases:

>100_bases
GCGAAGCGCTTTACGGGTTGGTCCGGCTGTGCCCCATGCTGCCGGGCCGGCTGACATTTTTATCGACGAGGGAGGGCAGC
ATCGTGAATATTGCAGGCTA

Product: putative bifunctional oxidoreductase/alginate lyase

Products: NADP(+); Semiquinone. [C]

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MKAIGYYRNLPVSDPESLVDLTLPEPVPGERDLLVEVRAVSVNPVDVKVRAGMAPEAGQPKVIGWDAAGVVRAVGKGVTL
FKPGDKVWYAGSLLRAGTNSELHVVDERIVGQMPQTLDFAAAAALPLTTITAWELLFDRLNVPESAKPGGATLLVIGAAG
GVGSILVQLARKLTGLTVIGTASRPETTQWVSGLGAHHVIDHTKPLSEELKRIGFDGVDYIASLNQTDHHFEQIVASVNP
QGHIALIDDPELFDFRKLKTKSVSLHWEFMYTRSMFATPDQIRQHELLSRVASLIDSGVLRTTLNETFGTINAANLRRAH
ELIETNRARGKIVLEGF

Sequences:

>Translated_337_residues
MKAIGYYRNLPVSDPESLVDLTLPEPVPGERDLLVEVRAVSVNPVDVKVRAGMAPEAGQPKVIGWDAAGVVRAVGKGVTL
FKPGDKVWYAGSLLRAGTNSELHVVDERIVGQMPQTLDFAAAAALPLTTITAWELLFDRLNVPESAKPGGATLLVIGAAG
GVGSILVQLARKLTGLTVIGTASRPETTQWVSGLGAHHVIDHTKPLSEELKRIGFDGVDYIASLNQTDHHFEQIVASVNP
QGHIALIDDPELFDFRKLKTKSVSLHWEFMYTRSMFATPDQIRQHELLSRVASLIDSGVLRTTLNETFGTINAANLRRAH
ELIETNRARGKIVLEGF
>Mature_337_residues
MKAIGYYRNLPVSDPESLVDLTLPEPVPGERDLLVEVRAVSVNPVDVKVRAGMAPEAGQPKVIGWDAAGVVRAVGKGVTL
FKPGDKVWYAGSLLRAGTNSELHVVDERIVGQMPQTLDFAAAAALPLTTITAWELLFDRLNVPESAKPGGATLLVIGAAG
GVGSILVQLARKLTGLTVIGTASRPETTQWVSGLGAHHVIDHTKPLSEELKRIGFDGVDYIASLNQTDHHFEQIVASVNP
QGHIALIDDPELFDFRKLKTKSVSLHWEFMYTRSMFATPDQIRQHELLSRVASLIDSGVLRTTLNETFGTINAANLRRAH
ELIETNRARGKIVLEGF

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI47519420, Length=335, Percent_Identity=27.7611940298507, Blast_Score=101, Evalue=8e-22,
Organism=Homo sapiens, GI194239674, Length=202, Percent_Identity=33.1683168316832, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI13236495, Length=202, Percent_Identity=33.1683168316832, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI194239676, Length=178, Percent_Identity=34.8314606741573, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI24308257, Length=200, Percent_Identity=31.5, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI18379349, Length=191, Percent_Identity=37.696335078534, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI22538446, Length=343, Percent_Identity=28.2798833819242, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI22538444, Length=343, Percent_Identity=28.2798833819242, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI28557745, Length=202, Percent_Identity=31.6831683168317, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1790485, Length=331, Percent_Identity=29.3051359516616, Blast_Score=92, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17507255, Length=231, Percent_Identity=31.6017316017316, Blast_Score=88, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI71987554, Length=192, Percent_Identity=31.7708333333333, Blast_Score=76, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6319520, Length=322, Percent_Identity=27.9503105590062, Blast_Score=79, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR014182
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: 1.6.5.5 [C]

Molecular weight: Translated: 36584; Mature: 36584

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAIGYYRNLPVSDPESLVDLTLPEPVPGERDLLVEVRAVSVNPVDVKVRAGMAPEAGQP
CCCCCCCCCCCCCCHHHHEEEECCCCCCCCCCEEEEEEEEECCCEEEEEECCCCCCCCCC
KVIGWDAAGVVRAVGKGVTLFKPGDKVWYAGSLLRAGTNSELHVVDERIVGQMPQTLDFA
CEEEECHHHHHHHHCCCEEEECCCCCEEEECHHHCCCCCCCEEEHHHHHHCCCCCHHHHH
AAAALPLTTITAWELLFDRLNVPESAKPGGATLLVIGAAGGVGSILVQLARKLTGLTVIG
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCEEEEE
TASRPETTQWVSGLGAHHVIDHTKPLSEELKRIGFDGVDYIASLNQTDHHFEQIVASVNP
CCCCCCHHHHHHCCCCHHHHCCCCCHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHCCC
QGHIALIDDPELFDFRKLKTKSVSLHWEFMYTRSMFATPDQIRQHELLSRVASLIDSGVL
CCCEEEECCCCCHHHHHHCCCEEEEEEEEEEECCHHCCHHHHHHHHHHHHHHHHHHCCHH
RTTLNETFGTINAANLRRAHELIETNRARGKIVLEGF
HHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEEECC
>Mature Secondary Structure
MKAIGYYRNLPVSDPESLVDLTLPEPVPGERDLLVEVRAVSVNPVDVKVRAGMAPEAGQP
CCCCCCCCCCCCCCHHHHEEEECCCCCCCCCCEEEEEEEEECCCEEEEEECCCCCCCCCC
KVIGWDAAGVVRAVGKGVTLFKPGDKVWYAGSLLRAGTNSELHVVDERIVGQMPQTLDFA
CEEEECHHHHHHHHCCCEEEECCCCCEEEECHHHCCCCCCCEEEHHHHHHCCCCCHHHHH
AAAALPLTTITAWELLFDRLNVPESAKPGGATLLVIGAAGGVGSILVQLARKLTGLTVIG
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCEEEEE
TASRPETTQWVSGLGAHHVIDHTKPLSEELKRIGFDGVDYIASLNQTDHHFEQIVASVNP
CCCCCCHHHHHHCCCCHHHHCCCCCHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHCCC
QGHIALIDDPELFDFRKLKTKSVSLHWEFMYTRSMFATPDQIRQHELLSRVASLIDSGVL
CCCEEEECCCCCHHHHHHCCCEEEEEEEEEEECCHHCCHHHHHHHHHHHHHHHHHHCCHH
RTTLNETFGTINAANLRRAHELIETNRARGKIVLEGF
HHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.017 {9,10-phenanthrenequinone}} 0.0153 {2,6-dichlorophenolindophenol}} 0.013 {2,6-dichlorophenolindophenol}} 0.007 {NADPH}} 0.0069 {NADPH}} 0.0024 {1,2-naphthoquinone}} 0.26 {1,4-naphthoquinone}} 0.065 {1,4-benzoquinone}} [C]

Substrates: NADPH; Quinone [C]

Specific reaction: NADPH + Quinone = NADP(+) + Semiquinone. [C]

General reaction: Oxidation; Reduction [C]

Inhibitor: 2, 3-Dimercaptopropanol; 2, 5-Dichloro-3, 6-dihydroxy -1, 4-benzoquinone; 4-Hydroxy coumarin; 5, 5'-Dithiobis (2-nitrobenzoate); ADP; Cibacronblue3GA; Coumarin; Cu2+; Dicoumarol warfarin, coumarin; Dithiothreitol preincubation with 9, 10-phenanthrenequino

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA