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The map label for this gene is pcaK [H]

Identifier: 91783092

GI number: 91783092

Start: 1938587

End: 1939924

Strand: Direct

Name: pcaK [H]

Synonym: Bxe_A2718

Alternate gene names: 91783092

Gene position: 1938587-1939924 (Clockwise)

Preceding gene: 91783091

Following gene: 91783093

Centisome position: 39.6

GC content: 55.61

Gene sequence:

>1338_bases
ATGTCCAAGGTAGTCGTTCTGGAAGATGTCGTCGACCGGCAACGGTTTAACACGGTTCGAGTCGCTGTCATCGTCCTGTG
CTTTCTGGTCATGTTTTTCGATGGCTACGAACTCAATCTGATCGGATATGTCGGGCCGGCTCTCATTTCGCATTTTTCCA
TAAGCAAGGCGGCGTTTGGCCCGGTTATTTCCGCCGGCCTCGCCGGGTTCATGCTGGGCGCCCTTATGTTGGGGGATTTG
GGAGACCGCTTTGGCCGCAAGCGCGTGATCATCGCCGGGACCATACTTTTCGGCGCGCTCACACTGATTGCTGCCTGGAG
CAGTTCGCTGGGTATCTTCATTGCGCTGAGATTCGTCGCTGGGTTAGGTCTGGGAGGTGCGGTGCCTAATGCCGTTGCGC
TGAACGCGGAGTTCGCACCTGCGCGTGTGCGAGCAACGACGATCGGGGTGATGTTTGTCGGCTATACGCTAGGCGGCGCC
GCCCCGGGATGGGCCGCTGCGGTGTTACTCAAGGAATTTGGCTGGCGCAGTGTCTTCTACTTGGGATCCTGCCTGCCGCT
GCTCATCGCTGCGACGATGATCTTCATCTTGCCGGAGTCAGTACGTTTCCTTGCAGCAAACAAACGAATAAAGGAACTGC
GCATACTGCTCGCCAAGATGCAGGATGAACCGTTGCCCGTCGGCGATTTCGAAATTTTGTCCAACGAGGTGAAAGCCCCG
GGATCGCCGTCGTTGCAACTTTTTAAAGATGGTCGTGGACCAGATACGCTATTTCTCTGGTTCGCATTTGTATCCTGCCT
GACCAGTATTCTGTTCGTGATGGCGTGGAGTCCGACCTTAGTTGCCGGACTTGGCATCGATCCGGGGCGTGCTGCGCTGA
TTGGCGCGATGTGGCAGACAGGTGGTGCGATCGGTTCCTTGCTGATTACACGTCTGCTCGATCGATTTGGAATATTGACG
ATTGCATTTTCAGTTTTGCTCGCCATACCACTTGTAATTCTGATAGGAAGAGTCGGTACGTCGGAGACAGTTCTGATGAT
CGTCATTCTGATTGGCGGATTGCTGGGGTCCGGCGGTCAGGTTGGTCTCAATGCGATTGCGGGAACGATCTATCCGACGA
TGATTCGTTCGACAGGCGTAGGTTGGGCGTTCGGAATGGGGCGGGTTGGCGCCATTCTAGGGCCTCTGATTGGCGGCTCT
CTTGTTGCCGCCGGCTTGGATGTTCGAAACCTGTATGTCGTAATGTCCTTGCCGTTTGCCCTGACGGCGCTATCCGTGGC
ACTTCTGTTTTTCCGAGGTACGAAACGTGCCAGGCTGGTTGATGCGCTCACAGGTTGA

Upstream 100 bases:

>100_bases
TAATCTTGCCGGGGCGCGTAATTGAAGTGGCGAATGCGGACGATATCCCGTTTCGGCGGGCCCCAGATTTCCAACAAATG
AGAGACAAGGTTCGGCAATT

Downstream 100 bases:

>100_bases
ATAATTGTAGGACCATGTGGCAGACGATCCCGTTCCCGTACACCCACACACTCTTGAAAATTGACTGATCCACCGAGATC
GCTGGTGCTGCCTGGAAGGT

Product: major facilitator superfamily aromatic acid transporter

Products: Proton [Cytoplasm]; 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MSKVVVLEDVVDRQRFNTVRVAVIVLCFLVMFFDGYELNLIGYVGPALISHFSISKAAFGPVISAGLAGFMLGALMLGDL
GDRFGRKRVIIAGTILFGALTLIAAWSSSLGIFIALRFVAGLGLGGAVPNAVALNAEFAPARVRATTIGVMFVGYTLGGA
APGWAAAVLLKEFGWRSVFYLGSCLPLLIAATMIFILPESVRFLAANKRIKELRILLAKMQDEPLPVGDFEILSNEVKAP
GSPSLQLFKDGRGPDTLFLWFAFVSCLTSILFVMAWSPTLVAGLGIDPGRAALIGAMWQTGGAIGSLLITRLLDRFGILT
IAFSVLLAIPLVILIGRVGTSETVLMIVILIGGLLGSGGQVGLNAIAGTIYPTMIRSTGVGWAFGMGRVGAILGPLIGGS
LVAAGLDVRNLYVVMSLPFALTALSVALLFFRGTKRARLVDALTG

Sequences:

>Translated_445_residues
MSKVVVLEDVVDRQRFNTVRVAVIVLCFLVMFFDGYELNLIGYVGPALISHFSISKAAFGPVISAGLAGFMLGALMLGDL
GDRFGRKRVIIAGTILFGALTLIAAWSSSLGIFIALRFVAGLGLGGAVPNAVALNAEFAPARVRATTIGVMFVGYTLGGA
APGWAAAVLLKEFGWRSVFYLGSCLPLLIAATMIFILPESVRFLAANKRIKELRILLAKMQDEPLPVGDFEILSNEVKAP
GSPSLQLFKDGRGPDTLFLWFAFVSCLTSILFVMAWSPTLVAGLGIDPGRAALIGAMWQTGGAIGSLLITRLLDRFGILT
IAFSVLLAIPLVILIGRVGTSETVLMIVILIGGLLGSGGQVGLNAIAGTIYPTMIRSTGVGWAFGMGRVGAILGPLIGGS
LVAAGLDVRNLYVVMSLPFALTALSVALLFFRGTKRARLVDALTG
>Mature_444_residues
SKVVVLEDVVDRQRFNTVRVAVIVLCFLVMFFDGYELNLIGYVGPALISHFSISKAAFGPVISAGLAGFMLGALMLGDLG
DRFGRKRVIIAGTILFGALTLIAAWSSSLGIFIALRFVAGLGLGGAVPNAVALNAEFAPARVRATTIGVMFVGYTLGGAA
PGWAAAVLLKEFGWRSVFYLGSCLPLLIAATMIFILPESVRFLAANKRIKELRILLAKMQDEPLPVGDFEILSNEVKAPG
SPSLQLFKDGRGPDTLFLWFAFVSCLTSILFVMAWSPTLVAGLGIDPGRAALIGAMWQTGGAIGSLLITRLLDRFGILTI
AFSVLLAIPLVILIGRVGTSETVLMIVILIGGLLGSGGQVGLNAIAGTIYPTMIRSTGVGWAFGMGRVGAILGPLIGGSL
VAAGLDVRNLYVVMSLPFALTALSVALLFFRGTKRARLVDALTG

Specific function: Could Be A Transporter For 3-Phenylpropionate (Hydrocinnamic Acid). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI24308167, Length=433, Percent_Identity=26.5588914549654, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI296080721, Length=152, Percent_Identity=34.2105263157895, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI296080719, Length=152, Percent_Identity=34.2105263157895, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI24497499, Length=152, Percent_Identity=34.2105263157895, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI296080734, Length=152, Percent_Identity=34.2105263157895, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI7662270, Length=201, Percent_Identity=24.8756218905473, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI262399383, Length=188, Percent_Identity=25, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI4506999, Length=346, Percent_Identity=28.0346820809249, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI166064021, Length=377, Percent_Identity=24.4031830238727, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI87081723, Length=425, Percent_Identity=30.1176470588235, Blast_Score=158, Evalue=7e-40,
Organism=Escherichia coli, GI1786229, Length=393, Percent_Identity=25.1908396946565, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87082159, Length=385, Percent_Identity=26.7532467532467, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI87082231, Length=456, Percent_Identity=23.6842105263158, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788074, Length=357, Percent_Identity=24.0896358543417, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1788068, Length=350, Percent_Identity=27.1428571428571, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789152, Length=330, Percent_Identity=23.6363636363636, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI32564663, Length=427, Percent_Identity=25.2927400468384, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI19922874, Length=410, Percent_Identity=24.390243902439, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24648211, Length=349, Percent_Identity=25.7879656160458, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24640198, Length=468, Percent_Identity=21.5811965811966, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24640196, Length=468, Percent_Identity=21.5811965811966, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24640200, Length=468, Percent_Identity=21.5811965811966, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004746
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46794; Mature: 46663

Theoretical pI: Translated: 10.40; Mature: 10.40

Prosite motif: PS50850 MFS ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHCCCCHHHHHHHHCC
>Mature Secondary Structure 
SKVVVLEDVVDRQRFNTVRVAVIVLCFLVMFFDGYELNLIGYVGPALISHFSISKAAFG
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHH
PVISAGLAGFMLGALMLGDLGDRFGRKRVIIAGTILFGALTLIAAWSSSLGIFIALRFVA
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHH
GLGLGGAVPNAVALNAEFAPARVRATTIGVMFVGYTLGGAAPGWAAAVLLKEFGWRSVFY
HCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHH
LGSCLPLLIAATMIFILPESVRFLAANKRIKELRILLAKMQDEPLPVGDFEILSNEVKAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCC
GSPSLQLFKDGRGPDTLFLWFAFVSCLTSILFVMAWSPTLVAGLGIDPGRAALIGAMWQT
CCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHEEECCCCCCHHHHHHHHHHC
GGAIGSLLITRLLDRFGILTIAFSVLLAIPLVILIGRVGTSETVLMIVILIGGLLGSGGQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCC
VGLNAIAGTIYPTMIRSTGVGWAFGMGRVGAILGPLIGGSLVAAGLDVRNLYVVMSLPFA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHCCCCHHHEEEEHHHHHH
LTALSVALLFFRGTKRARLVDALTG
HHHHHHHHHHHCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; 3-(3-hydroxyphenyl)propionate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + 3-(3-hydroxyphenyl)propionate [Periplasm] = Proton [Cytoplasm] + 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8063101 [H]