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The map label for this gene is yngE [H]

Identifier: 91783049

GI number: 91783049

Start: 1892675

End: 1894273

Strand: Direct

Name: yngE [H]

Synonym: Bxe_A2761

Alternate gene names: 91783049

Gene position: 1892675-1894273 (Clockwise)

Preceding gene: 91783048

Following gene: 91783050

Centisome position: 38.66

GC content: 64.79

Gene sequence:

>1599_bases
GTGAGTACCATCCTCTCCCGCATCGATCGCCAGTCCGACGCGTTCAGGAACAACGAAGCGCACTACGACGCGCTGCTCGC
CGAACTGCGCGAACGCCACGCGCATGTGCTGGCGGGTGGCGGCGAGCGGCTGGTCGAACGGCATCATGCGCGCAACAAGA
TGCTCGCGCGTGAACGGATCGACCTGCTGCTCGACCCGCTGTCGCCGTTTCTCGAACTGTCGCCGCTCGCGGCCTGGGGC
ATGTACGGCAACGCGGTGCCGTCAGCCGGCGTGATTACCGGTATCGGCCTGATCGCGGGCACGCCCTGCATGCTGATCGC
CAATGACGCCACCGTGAAGGGCGGTTCGTTCTTCGCCGAGACCGTCAAGAAACACGTGCGCGCGCAGGACATTGCCGGGC
ATCACCGTTTGCCGGTCATTTATCTGGTCGATTGCGGCGGTGCGTATCTGCCGGAACAGGATCGTGTGTTCCCCGACAAG
GACCACTTCGGCAATACGTTCTACCGGCAATGCCAGATGTCCGCCGCGGGCATTCCGCAGATCGCCGCCGTGTTCGGCGG
CTGCACGGCGGGTGGCGCATACATACCCGCGCTCGCCGACGAAGTCGTGATGGTACGCGGCCAGGCACGCATTCATCTGG
GCGGCCCGCAGATCGTCAAGGCGGCGATCAACGAAATCGTCGACGGCGAGACGCTCGGCGGCGCCGAGATGCACACGCGC
GTGTCCGGCGTCTCCGACTATCTGGCGGAAAACGAAGCACAGGCGCTCCAGCGCGTGCGCGACATCATCGCCAATCTGAA
CCGGCCACGGCCGCTTTCCGGCGCGGTGCGCGAAGTCGTGCCGCCGCGCTATGACATCGGCGAGTTGCGCGGCATCCTGC
CGCCGGGGCTGAAGGAATCGTATGACGTGCGCGAAGTGATCGCGCGGCTCGTCGACGATTCCGGGTTCCAGGAATTCAAG
CCCGAGTTCGGCAGCACGCTCGTGTGCGGCACTGCATACTGGTGCGGTTATCCGGTTGGAATTCTCGCCAACAATGGCGT
GCTGTTTTCAGAGTCGGCCACGAAGGGTGCGCATTTCATCGAACTGTGCAACCAGCGCAATATTCCACTGCTGTTTCTGC
AGAACATCACTGGCTTCATGGTGGGTACGGAGGCCGAGCGCGGCGGCATTGCAAGGCACAGCGCGAAGCTCGTCTACGCA
ATGGCGACTGCGCGCGTGCCGCGCCTCACGGTGATCATCGGCGGCTCGTTCGGCGCGGGCAACTACGGTATGTGCGGTCG
CGGTTTCGATCCGCGCTTCCTGTTCGCGTGGCCGAACTCGCGAATCGCGACCATGAGCGCGGACGTGGCGGCGACCGTGC
TGACCGACTTGCGGCGCAGCAGTCTGAAAGCCGCCGCCGATGAAGCCGAGATCGCCGAAATCGATCGCGTCACGCGCGAG
CAGTTCACCACGCAAAGCGATCCGTATTACGCCACCGCGCGCCTGTGGGACGACGGGCTGATCGAGCCTTCGGAAACGCG
CGAAGTGATCGGCCTGTGCCTCGCACTCGCGGCGGCCGAAGCGCCGGCGACGGGTCCTTCACCCGTCTTCCGGATGTAA

Upstream 100 bases:

>100_bases
CGGCAGCGGCGAAACTGCAGCCGGGTACGCGCGTGCGTGTCGAGTTCATCGATGCGCCGCAAGGCCGCATTACCGATTTC
CACTACGTGCTGGCCGCCGC

Downstream 100 bases:

>100_bases
AGGCAAACATGTTCGAATCCATTCTTATCGCGAACCGTGGCGAAATCGCCTGCCGGATCGCACGCACCAGCCGCCGGCTG
GGCATTCGCGTCATCGCTGT

Product: propionyl-CoA carboxylase

Products: ADP; phosphate; (S)-methylmalonyl-CoA

Alternate protein names: NA

Number of amino acids: Translated: 532; Mature: 531

Protein sequence:

>532_residues
MSTILSRIDRQSDAFRNNEAHYDALLAELRERHAHVLAGGGERLVERHHARNKMLARERIDLLLDPLSPFLELSPLAAWG
MYGNAVPSAGVITGIGLIAGTPCMLIANDATVKGGSFFAETVKKHVRAQDIAGHHRLPVIYLVDCGGAYLPEQDRVFPDK
DHFGNTFYRQCQMSAAGIPQIAAVFGGCTAGGAYIPALADEVVMVRGQARIHLGGPQIVKAAINEIVDGETLGGAEMHTR
VSGVSDYLAENEAQALQRVRDIIANLNRPRPLSGAVREVVPPRYDIGELRGILPPGLKESYDVREVIARLVDDSGFQEFK
PEFGSTLVCGTAYWCGYPVGILANNGVLFSESATKGAHFIELCNQRNIPLLFLQNITGFMVGTEAERGGIARHSAKLVYA
MATARVPRLTVIIGGSFGAGNYGMCGRGFDPRFLFAWPNSRIATMSADVAATVLTDLRRSSLKAAADEAEIAEIDRVTRE
QFTTQSDPYYATARLWDDGLIEPSETREVIGLCLALAAAEAPATGPSPVFRM

Sequences:

>Translated_532_residues
MSTILSRIDRQSDAFRNNEAHYDALLAELRERHAHVLAGGGERLVERHHARNKMLARERIDLLLDPLSPFLELSPLAAWG
MYGNAVPSAGVITGIGLIAGTPCMLIANDATVKGGSFFAETVKKHVRAQDIAGHHRLPVIYLVDCGGAYLPEQDRVFPDK
DHFGNTFYRQCQMSAAGIPQIAAVFGGCTAGGAYIPALADEVVMVRGQARIHLGGPQIVKAAINEIVDGETLGGAEMHTR
VSGVSDYLAENEAQALQRVRDIIANLNRPRPLSGAVREVVPPRYDIGELRGILPPGLKESYDVREVIARLVDDSGFQEFK
PEFGSTLVCGTAYWCGYPVGILANNGVLFSESATKGAHFIELCNQRNIPLLFLQNITGFMVGTEAERGGIARHSAKLVYA
MATARVPRLTVIIGGSFGAGNYGMCGRGFDPRFLFAWPNSRIATMSADVAATVLTDLRRSSLKAAADEAEIAEIDRVTRE
QFTTQSDPYYATARLWDDGLIEPSETREVIGLCLALAAAEAPATGPSPVFRM
>Mature_531_residues
STILSRIDRQSDAFRNNEAHYDALLAELRERHAHVLAGGGERLVERHHARNKMLARERIDLLLDPLSPFLELSPLAAWGM
YGNAVPSAGVITGIGLIAGTPCMLIANDATVKGGSFFAETVKKHVRAQDIAGHHRLPVIYLVDCGGAYLPEQDRVFPDKD
HFGNTFYRQCQMSAAGIPQIAAVFGGCTAGGAYIPALADEVVMVRGQARIHLGGPQIVKAAINEIVDGETLGGAEMHTRV
SGVSDYLAENEAQALQRVRDIIANLNRPRPLSGAVREVVPPRYDIGELRGILPPGLKESYDVREVIARLVDDSGFQEFKP
EFGSTLVCGTAYWCGYPVGILANNGVLFSESATKGAHFIELCNQRNIPLLFLQNITGFMVGTEAERGGIARHSAKLVYAM
ATARVPRLTVIIGGSFGAGNYGMCGRGFDPRFLFAWPNSRIATMSADVAATVLTDLRRSSLKAAADEAEIAEIDRVTREQ
FTTQSDPYYATARLWDDGLIEPSETREVIGLCLALAAAEAPATGPSPVFRM

Specific function: Unknown

COG id: COG4799

COG function: function code I; Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI11545863, Length=540, Percent_Identity=53.5185185185185, Blast_Score=539, Evalue=1e-153,
Organism=Homo sapiens, GI119943100, Length=505, Percent_Identity=34.2574257425743, Blast_Score=244, Evalue=2e-64,
Organism=Homo sapiens, GI295821216, Length=525, Percent_Identity=33.1428571428571, Blast_Score=232, Evalue=7e-61,
Organism=Homo sapiens, GI310133460, Length=143, Percent_Identity=49.6503496503497, Blast_Score=124, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17552936, Length=533, Percent_Identity=51.5947467166979, Blast_Score=551, Evalue=1e-157,
Organism=Caenorhabditis elegans, GI25147359, Length=503, Percent_Identity=34.7912524850895, Blast_Score=257, Evalue=9e-69,
Organism=Caenorhabditis elegans, GI25147362, Length=503, Percent_Identity=34.7912524850895, Blast_Score=257, Evalue=1e-68,
Organism=Drosophila melanogaster, GI24586065, Length=550, Percent_Identity=53.6363636363636, Blast_Score=577, Evalue=1e-165,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000022
- InterPro:   IPR011763
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: 6.4.1.3

Molecular weight: Translated: 57546; Mature: 57415

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: PS50980 COA_CT_NTER ; PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTILSRIDRQSDAFRNNEAHYDALLAELRERHAHVLAGGGERLVERHHARNKMLARERI
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHH
DLLLDPLSPFLELSPLAAWGMYGNAVPSAGVITGIGLIAGTPCMLIANDATVKGGSFFAE
HHHHHHHHHHHHHCCHHHHCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCEECCCHHHHH
TVKKHVRAQDIAGHHRLPVIYLVDCGGAYLPEQDRVFPDKDHFGNTFYRQCQMSAAGIPQ
HHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHH
IAAVFGGCTAGGAYIPALADEVVMVRGQARIHLGGPQIVKAAINEIVDGETLGGAEMHTR
HHHHHCCCCCCCCCHHHHHCCEEEEECCEEEEECCHHHHHHHHHHHHCCCCCCCHHHHHH
VSGVSDYLAENEAQALQRVRDIIANLNRPRPLSGAVREVVPPRYDIGELRGILPPGLKES
HHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCHHHHHCCCCCCCCCC
YDVREVIARLVDDSGFQEFKPEFGSTLVCGTAYWCGYPVGILANNGVLFSESATKGAHFI
CCHHHHHHHHHCCCCCHHHCHHHCCEEEECCHHHHCCCEEEEECCCEEEECCCCCCHHHH
ELCNQRNIPLLFLQNITGFMVGTEAERGGIARHSAKLVYAMATARVPRLTVIIGGSFGAG
HHHCCCCCCEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCC
NYGMCGRGFDPRFLFAWPNSRIATMSADVAATVLTDLRRSSLKAAADEAEIAEIDRVTRE
CCCCCCCCCCCCEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
QFTTQSDPYYATARLWDDGLIEPSETREVIGLCLALAAAEAPATGPSPVFRM
HHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
STILSRIDRQSDAFRNNEAHYDALLAELRERHAHVLAGGGERLVERHHARNKMLARERI
CHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHH
DLLLDPLSPFLELSPLAAWGMYGNAVPSAGVITGIGLIAGTPCMLIANDATVKGGSFFAE
HHHHHHHHHHHHHCCHHHHCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCEECCCHHHHH
TVKKHVRAQDIAGHHRLPVIYLVDCGGAYLPEQDRVFPDKDHFGNTFYRQCQMSAAGIPQ
HHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHH
IAAVFGGCTAGGAYIPALADEVVMVRGQARIHLGGPQIVKAAINEIVDGETLGGAEMHTR
HHHHHCCCCCCCCCHHHHHCCEEEEECCEEEEECCHHHHHHHHHHHHCCCCCCCHHHHHH
VSGVSDYLAENEAQALQRVRDIIANLNRPRPLSGAVREVVPPRYDIGELRGILPPGLKES
HHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCHHHHHCCCCCCCCCC
YDVREVIARLVDDSGFQEFKPEFGSTLVCGTAYWCGYPVGILANNGVLFSESATKGAHFI
CCHHHHHHHHHCCCCCHHHCHHHCCEEEECCHHHHCCCEEEEECCCEEEECCCCCCHHHH
ELCNQRNIPLLFLQNITGFMVGTEAERGGIARHSAKLVYAMATARVPRLTVIIGGSFGAG
HHHCCCCCCEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCC
NYGMCGRGFDPRFLFAWPNSRIATMSADVAATVLTDLRRSSLKAAADEAEIAEIDRVTRE
CCCCCCCCCCCCEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
QFTTQSDPYYATARLWDDGLIEPSETREVIGLCLALAAAEAPATGPSPVFRM
HHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; propanoyl-CoA; HCO3-

Specific reaction: ATP + propanoyl-CoA + HCO3- = ADP + phosphate + (S)-methylmalonyl-CoA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 9387222 [H]