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The map label for this gene is zraR [H]

Identifier: 91783019

GI number: 91783019

Start: 1861002

End: 1862393

Strand: Direct

Name: zraR [H]

Synonym: Bxe_A2790

Alternate gene names: 91783019

Gene position: 1861002-1862393 (Clockwise)

Preceding gene: 91783018

Following gene: 91783020

Centisome position: 38.01

GC content: 64.66

Gene sequence:

>1392_bases
ATGAGAACCACCACCAAAATCGAGGAACTCGATATCTACGTCTGGGAGGGCAAGGCCGACATCGTCGACCGGGTCGCGCG
CTGCATGGCGAGCTTCGACGTCGAAGTGATCCGTGCTGACGATATCGCGATCTCGCCCGAGCGGACCGCGCTGCGGCCGT
CGCTCGCAATCATCAGCGTATCCGTGATCGACAGCGGCGCGCTGATCCTGCGCGACTGGCAGGCGGCGCACGGCATCCCG
GTAGTGTGGGTCGGCGCCGCGCCGCGCGAACACGATCCGGCCACCTATCCGTCCGAGTACTCGCATATCCTGCCGCTCGA
CTTCACCTGCGCCGAATTGCGTGGCATGGTCATGAAGCTCGTGCTGCAAATGCGCGCGCACAGCGCGAAGACGCACGAGT
CCGACGCGATGATCGCCAACTCGGAGTGCATGCAGGCGCTGCTGCACGAAGTCGACACCTTCGCCGATTGCGACACCAGT
GTGCTGGTGCATGGCGAAACCGGCGTCGGCAAGGAGCGCATCGCGCAACTGCTGCACGAAAAACATAGCCGCTACGGGCA
AGGCCCGTTCGTCGCGGTGAACTGCGGCGCGATTCCGGACGGGCTGTTCGAGTCGCTGTTCTTCGGTCACTCGAAAGGCT
CGTTCACCGGCGCGGTGGTCGCGCACAAAGGCTACTTCGAGCAGGCCGACGGCGGCACGCTGTTCCTCGACGAAATCGGC
GATCTGCCGCTCTATCAGCAGGTCAAGCTGCTGCGCGTGCTCGAAGACAGCGCGGTGACGCGCATTGGTTCGGCGACGCC
GGTGAAGCTCGACTTCCGGCTGGTGGCGGCGACCAACAAACTGCTGCCGCAACTGGTGAAAGACGGCACGTTTCGCGCCG
ACCTCTACTACCGGCTTGCCGTGATCGAGTTGAAAATTCCGTCACTGGAAGAGCGGGGCGCCGTCGACAAGATCGCCATC
TTCAAGGCGTTCATTGCGCAGATCGTCGGCACCGAGCGTCTCGCCGCGCTGCCCGACCTGCCGTACTGGCTCGCCGACGC
CGTCGCGGACACCTACTTCCCCGGCAACGTGCGCGAACTGCGCAACCTGGCCGAACGCATCGGCGTGACCGTGCGCCAGA
TCGGTGCGTGGGACGCGGCGCGCCTGCAACGCCTGCTCGCGCTCGCGCGCACCAGTCAGCCGGTGCCGGCCGAAAGCGTC
GCCGAGGTGCTGGTGGACCGCAGCAAGTGGGACATGGCCGAACGCAACCGCGTGCTGGCCGCGCTCGACGCAAACGGTTG
GCGGCGCCAGGATACCGCGCTCTACCTGGGCATCAGCCGCAAGGTTCTGTGGGAGAAGATGCGCAAATACCAAATTTTCG
ACGAAGAGCCCGAAACACGCGAAAGTGAGTAA

Upstream 100 bases:

>100_bases
CCCACACTGTCCCTGTTGGGCGTTCAGGTCGGCACCGCCACGGTCCACAACATGTCGCTGACGTGCGGCGTCGCGCAACT
GGTCAACTAGCCTATCCAAG

Downstream 100 bases:

>100_bases
TAATGAGACGGTTGTACTAAAACAAAAACTGTTCAAGCAGGAATTACATGGACCGAAAGTCGAAACTACGACAGATTGCC
TTCGCCGCAGTCATCGCGAT

Product: sigma-54 dependent trancsriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MRTTTKIEELDIYVWEGKADIVDRVARCMASFDVEVIRADDIAISPERTALRPSLAIISVSVIDSGALILRDWQAAHGIP
VVWVGAAPREHDPATYPSEYSHILPLDFTCAELRGMVMKLVLQMRAHSAKTHESDAMIANSECMQALLHEVDTFADCDTS
VLVHGETGVGKERIAQLLHEKHSRYGQGPFVAVNCGAIPDGLFESLFFGHSKGSFTGAVVAHKGYFEQADGGTLFLDEIG
DLPLYQQVKLLRVLEDSAVTRIGSATPVKLDFRLVAATNKLLPQLVKDGTFRADLYYRLAVIELKIPSLEERGAVDKIAI
FKAFIAQIVGTERLAALPDLPYWLADAVADTYFPGNVRELRNLAERIGVTVRQIGAWDAARLQRLLALARTSQPVPAESV
AEVLVDRSKWDMAERNRVLAALDANGWRRQDTALYLGISRKVLWEKMRKYQIFDEEPETRESE

Sequences:

>Translated_463_residues
MRTTTKIEELDIYVWEGKADIVDRVARCMASFDVEVIRADDIAISPERTALRPSLAIISVSVIDSGALILRDWQAAHGIP
VVWVGAAPREHDPATYPSEYSHILPLDFTCAELRGMVMKLVLQMRAHSAKTHESDAMIANSECMQALLHEVDTFADCDTS
VLVHGETGVGKERIAQLLHEKHSRYGQGPFVAVNCGAIPDGLFESLFFGHSKGSFTGAVVAHKGYFEQADGGTLFLDEIG
DLPLYQQVKLLRVLEDSAVTRIGSATPVKLDFRLVAATNKLLPQLVKDGTFRADLYYRLAVIELKIPSLEERGAVDKIAI
FKAFIAQIVGTERLAALPDLPYWLADAVADTYFPGNVRELRNLAERIGVTVRQIGAWDAARLQRLLALARTSQPVPAESV
AEVLVDRSKWDMAERNRVLAALDANGWRRQDTALYLGISRKVLWEKMRKYQIFDEEPETRESE
>Mature_463_residues
MRTTTKIEELDIYVWEGKADIVDRVARCMASFDVEVIRADDIAISPERTALRPSLAIISVSVIDSGALILRDWQAAHGIP
VVWVGAAPREHDPATYPSEYSHILPLDFTCAELRGMVMKLVLQMRAHSAKTHESDAMIANSECMQALLHEVDTFADCDTS
VLVHGETGVGKERIAQLLHEKHSRYGQGPFVAVNCGAIPDGLFESLFFGHSKGSFTGAVVAHKGYFEQADGGTLFLDEIG
DLPLYQQVKLLRVLEDSAVTRIGSATPVKLDFRLVAATNKLLPQLVKDGTFRADLYYRLAVIELKIPSLEERGAVDKIAI
FKAFIAQIVGTERLAALPDLPYWLADAVADTYFPGNVRELRNLAERIGVTVRQIGAWDAARLQRLLALARTSQPVPAESV
AEVLVDRSKWDMAERNRVLAALDANGWRRQDTALYLGISRKVLWEKMRKYQIFDEEPETRESE

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG1221

COG function: function code KT; Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI87082117, Length=322, Percent_Identity=39.4409937888199, Blast_Score=205, Evalue=6e-54,
Organism=Escherichia coli, GI1790437, Length=353, Percent_Identity=36.8271954674221, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI1788550, Length=316, Percent_Identity=37.3417721518987, Blast_Score=202, Evalue=4e-53,
Organism=Escherichia coli, GI87081872, Length=326, Percent_Identity=35.2760736196319, Blast_Score=187, Evalue=9e-49,
Organism=Escherichia coli, GI1790299, Length=228, Percent_Identity=44.7368421052632, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI1788905, Length=238, Percent_Identity=42.8571428571429, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI1789087, Length=325, Percent_Identity=38.1538461538462, Blast_Score=185, Evalue=5e-48,
Organism=Escherichia coli, GI1789233, Length=393, Percent_Identity=32.5699745547074, Blast_Score=183, Evalue=2e-47,
Organism=Escherichia coli, GI1786524, Length=332, Percent_Identity=37.6506024096386, Blast_Score=182, Evalue=6e-47,
Organism=Escherichia coli, GI87082152, Length=292, Percent_Identity=37.6712328767123, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI1787583, Length=324, Percent_Identity=32.7160493827161, Blast_Score=148, Evalue=6e-37,
Organism=Escherichia coli, GI1789828, Length=154, Percent_Identity=41.5584415584416, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI87081858, Length=379, Percent_Identity=27.9683377308707, Blast_Score=106, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 51498; Mature: 51498

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTTTKIEELDIYVWEGKADIVDRVARCMASFDVEVIRADDIAISPERTALRPSLAIISV
CCCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCEEEEEECCEEECCCCHHCCCCEEEEEE
SVIDSGALILRDWQAAHGIPVVWVGAAPREHDPATYPSEYSHILPLDFTCAELRGMVMKL
EEECCCEEEEEECHHHCCCCEEEEECCCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHH
VLQMRAHSAKTHESDAMIANSECMQALLHEVDTFADCDTSVLVHGETGVGKERIAQLLHE
HHHHHHHCCCCCCCCCEEECHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHH
KHSRYGQGPFVAVNCGAIPDGLFESLFFGHSKGSFTGAVVAHKGYFEQADGGTLFLDEIG
HHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCEEEHHCCC
DLPLYQQVKLLRVLEDSAVTRIGSATPVKLDFRLVAATNKLLPQLVKDGTFRADLYYRLA
CCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEHHHHHHHHHHHHCCCEEEEEEEEEE
VIELKIPSLEERGAVDKIAIFKAFIAQIVGTERLAALPDLPYWLADAVADTYFPGNVREL
EEEEECCCCHHCCCHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHCCCCCCHHHH
RNLAERIGVTVRQIGAWDAARLQRLLALARTSQPVPAESVAEVLVDRSKWDMAERNRVLA
HHHHHHHCCHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHCCHHHCCCEEE
ALDANGWRRQDTALYLGISRKVLWEKMRKYQIFDEEPETRESE
EECCCCCCCCCCEEEEECHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MRTTTKIEELDIYVWEGKADIVDRVARCMASFDVEVIRADDIAISPERTALRPSLAIISV
CCCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCEEEEEECCEEECCCCHHCCCCEEEEEE
SVIDSGALILRDWQAAHGIPVVWVGAAPREHDPATYPSEYSHILPLDFTCAELRGMVMKL
EEECCCEEEEEECHHHCCCCEEEEECCCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHH
VLQMRAHSAKTHESDAMIANSECMQALLHEVDTFADCDTSVLVHGETGVGKERIAQLLHE
HHHHHHHCCCCCCCCCEEECHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHH
KHSRYGQGPFVAVNCGAIPDGLFESLFFGHSKGSFTGAVVAHKGYFEQADGGTLFLDEIG
HHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCEEEHHCCC
DLPLYQQVKLLRVLEDSAVTRIGSATPVKLDFRLVAATNKLLPQLVKDGTFRADLYYRLA
CCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEHHHHHHHHHHHHCCCEEEEEEEEEE
VIELKIPSLEERGAVDKIAIFKAFIAQIVGTERLAALPDLPYWLADAVADTYFPGNVREL
EEEEECCCCHHCCCHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHCCCCCCHHHH
RNLAERIGVTVRQIGAWDAARLQRLLALARTSQPVPAESVAEVLVDRSKWDMAERNRVLA
HHHHHHHCCHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHCCHHHCCCEEE
ALDANGWRRQDTALYLGISRKVLWEKMRKYQIFDEEPETRESE
EECCCCCCCCCCEEEEECHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]