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The map label for this gene is rluB [H]

Identifier: 91782986

GI number: 91782986

Start: 1817878

End: 1819779

Strand: Direct

Name: rluB [H]

Synonym: Bxe_A2823

Alternate gene names: 91782986

Gene position: 1817878-1819779 (Clockwise)

Preceding gene: 91782985

Following gene: 91782987

Centisome position: 37.13

GC content: 70.03

Gene sequence:

>1902_bases
TTGACACATACCCACGACACCGATTCGTCCGAATCCGAGCGCGCCGTGCCATCGGCTCGCGCCGACGAAACGCGCACCAC
TCAAGCGTCGGCAGGCGAGGGCGAGCGCCCGGCGCAGACCACGGAAGCAGACGGTGAAGACCGTCCGCGCCGCGGCCTGC
GTCGCGGGCCGCGCAGCCTGATCGCGCGGCGCCGCGCCGGCGCGAAGACGAAGGGCGCCGAAGGCGCCGCCGCGCAGGAG
GCGCCGGTTGTCGGCGAGGCGCCACCGGATGGCGAGGTCGTCGCGCAAGTGCGTATGCCGCGCAAGGATGCAGGCGCCAA
GGGTCAGGGATCGCGGCGCAATGCAGGCGGCGCGCGCCGCGAAGGCGCGCCGCGTGAAGGTGCCGCACGTGAAGGCGCAC
CTCGCGAAGGCCAGCGCGAGCGTCAGCCGCGTGAAGGTCAGCCGCGCGAAGGCGGCCAGCGTCAGAATCGCCGCGGCGGT
GAAGCGCCGGCGGTTGCGACGGAGGCGGGTCAGGACGATCTGTTCTCGTACGTCACGTCGCCCGCCTTCGACGCGGACAA
CAGCGCCACCGGCGGCGTGCGCGCTCCGATGCTGCGTCGTGGCAAGCCGGTCGCGCCCAAGCGCGTACTCGCCGCGGACG
ACGACGCACCAAAGCTGCACAAAGTGCTGGCCGAAGCCGGCATGGGTTCGCGCCGCGACATGGAAGAGCTGATCGTTGCC
GGCCGGGTGTCGGTGAATGGCGAGCCGGCTCATATCGGCCAGCGCATCATGCCGACCGACCAGGTTCGCATCAACGGCAA
GCCGGTCAAGCGCAAACTGGCCAGCAAGCCGCCGCGTGTGCTGCTGTATCACAAACCGACCGGCGAAATCGTCAGCCATG
CCGATCCGGAAGGCCGTCCTTCGGTGTTCGACAAGCTGCCGCCGATGAAAACCGCCAAGTGGCTCGCGGTCGGCCGTCTC
GATTTCAACACGGAAGGTCTGCTGATGCTGACCACGTCGGGCGATCTGGCGAACCGTTTCATGCACCCGCGTTATAGCGT
CGAGCGTGAATATGCGGTGCGCGTGGTCGGCGAACTGGCCGAAGGCATGCGTCAGAAGCTTCTGCATGGCGTCGAGCTGG
ACGACGGCCCGGCGAACTTCCTGCGGATTCGCGACGGCGGCGGCGAAGGCACCAATCACTGGTATCACGTCGCGCTCGCC
GAAGGGCGTAACCGCGAAGTGCGTCGTATGTTCGAAGCGGCCGGCCTGATGGTCAGCCGCCTGATCCGTACCCGTCACGG
CCCGATCTCGCTGCCCAAGGGGCTCAAGCGCGGTCGTTGGGAAGAGTTGGAAGACAACCAGGTGCGTGCACTGATGGCGT
CGGTGGGCCTGAAGGCGCCGACTGAAGAGCGCGGCAGCCGCAATGCGGCGCCGGAACGCAAGCAGCCGGATCCGATGCAA
ACGTCGATGGGTTTCATTAACCGTGAGCCGGTGTTGATGTCGCATGGCCGTTTCGATCAGCAGCCGCCACGCGGCCAGGG
GCGGCGCGGTGGTGCGGCAGGCGGCGGTTTTGCTGGCGGCGCGGGCGCGGGTTTTGGCGGCGGCTATGGCAATCGCGGTG
CCGGCCGCAGCGCCGGTGGCTTCGGCGGCCCGATGGGCGCGGGTGGGGGTGCGGGCGGCCCGCGTGGCGGCCGTGAAGTC
GACGGCAACCGCGCGCCGTCGGGCAATGGCAATCGTGCGGCAGGCGGCGGCAAGCGTGTCGGCGGTGCCGGTGCCGGTGC
CAATCCGGGCAATGGCGGCAACAACCGCGGCCCGGCCGGCAATCGGGGCGGCAACGCCAATCGCGCGGGCGGCGGAAACG
CCAGTCCGGGCGGCGCCAATCGCGGCGGCGGCGCACCGCGCGGCCGTTCGCGTGGCCGTTGA

Upstream 100 bases:

>100_bases
CTGACCGACGACGAACCCGAGTCGCGCAGCGCCTGACGTAACCGAACTTTTTTTGCCACGCCCGCAACGGGCGTGCGCGA
CCTGACATTTTGAGGTTGTT

Downstream 100 bases:

>100_bases
GCAGTGGCCGTCGAGCAGTGGCCGTCGAGCAATAGGCAGGTCCTGCATGGCGGTCGGCCGCTCATCGTTCTTTAGCGATT
TTCGTCAGCCACCGTCGTAG

Product: ribosomal large subunit pseudouridine synthase B

Products: NA

Alternate protein names: rRNA pseudouridylate synthase B; rRNA-uridine isomerase B [H]

Number of amino acids: Translated: 633; Mature: 632

Protein sequence:

>633_residues
MTHTHDTDSSESERAVPSARADETRTTQASAGEGERPAQTTEADGEDRPRRGLRRGPRSLIARRRAGAKTKGAEGAAAQE
APVVGEAPPDGEVVAQVRMPRKDAGAKGQGSRRNAGGARREGAPREGAAREGAPREGQRERQPREGQPREGGQRQNRRGG
EAPAVATEAGQDDLFSYVTSPAFDADNSATGGVRAPMLRRGKPVAPKRVLAADDDAPKLHKVLAEAGMGSRRDMEELIVA
GRVSVNGEPAHIGQRIMPTDQVRINGKPVKRKLASKPPRVLLYHKPTGEIVSHADPEGRPSVFDKLPPMKTAKWLAVGRL
DFNTEGLLMLTTSGDLANRFMHPRYSVEREYAVRVVGELAEGMRQKLLHGVELDDGPANFLRIRDGGGEGTNHWYHVALA
EGRNREVRRMFEAAGLMVSRLIRTRHGPISLPKGLKRGRWEELEDNQVRALMASVGLKAPTEERGSRNAAPERKQPDPMQ
TSMGFINREPVLMSHGRFDQQPPRGQGRRGGAAGGGFAGGAGAGFGGGYGNRGAGRSAGGFGGPMGAGGGAGGPRGGREV
DGNRAPSGNGNRAAGGGKRVGGAGAGANPGNGGNNRGPAGNRGGNANRAGGGNASPGGANRGGGAPRGRSRGR

Sequences:

>Translated_633_residues
MTHTHDTDSSESERAVPSARADETRTTQASAGEGERPAQTTEADGEDRPRRGLRRGPRSLIARRRAGAKTKGAEGAAAQE
APVVGEAPPDGEVVAQVRMPRKDAGAKGQGSRRNAGGARREGAPREGAAREGAPREGQRERQPREGQPREGGQRQNRRGG
EAPAVATEAGQDDLFSYVTSPAFDADNSATGGVRAPMLRRGKPVAPKRVLAADDDAPKLHKVLAEAGMGSRRDMEELIVA
GRVSVNGEPAHIGQRIMPTDQVRINGKPVKRKLASKPPRVLLYHKPTGEIVSHADPEGRPSVFDKLPPMKTAKWLAVGRL
DFNTEGLLMLTTSGDLANRFMHPRYSVEREYAVRVVGELAEGMRQKLLHGVELDDGPANFLRIRDGGGEGTNHWYHVALA
EGRNREVRRMFEAAGLMVSRLIRTRHGPISLPKGLKRGRWEELEDNQVRALMASVGLKAPTEERGSRNAAPERKQPDPMQ
TSMGFINREPVLMSHGRFDQQPPRGQGRRGGAAGGGFAGGAGAGFGGGYGNRGAGRSAGGFGGPMGAGGGAGGPRGGREV
DGNRAPSGNGNRAAGGGKRVGGAGAGANPGNGGNNRGPAGNRGGNANRAGGGNASPGGANRGGGAPRGRSRGR
>Mature_632_residues
THTHDTDSSESERAVPSARADETRTTQASAGEGERPAQTTEADGEDRPRRGLRRGPRSLIARRRAGAKTKGAEGAAAQEA
PVVGEAPPDGEVVAQVRMPRKDAGAKGQGSRRNAGGARREGAPREGAAREGAPREGQRERQPREGQPREGGQRQNRRGGE
APAVATEAGQDDLFSYVTSPAFDADNSATGGVRAPMLRRGKPVAPKRVLAADDDAPKLHKVLAEAGMGSRRDMEELIVAG
RVSVNGEPAHIGQRIMPTDQVRINGKPVKRKLASKPPRVLLYHKPTGEIVSHADPEGRPSVFDKLPPMKTAKWLAVGRLD
FNTEGLLMLTTSGDLANRFMHPRYSVEREYAVRVVGELAEGMRQKLLHGVELDDGPANFLRIRDGGGEGTNHWYHVALAE
GRNREVRRMFEAAGLMVSRLIRTRHGPISLPKGLKRGRWEELEDNQVRALMASVGLKAPTEERGSRNAAPERKQPDPMQT
SMGFINREPVLMSHGRFDQQPPRGQGRRGGAAGGGFAGGAGAGFGGGYGNRGAGRSAGGFGGPMGAGGGAGGPRGGREVD
GNRAPSGNGNRAAGGGKRVGGAGAGANPGNGGNNRGPAGNRGGNANRAGGGNASPGGANRGGGAPRGRSRGR

Specific function: Responsible for synthesis of pseudouridine from uracil- 2605 in 23S ribosomal RNA [H]

COG id: COG1187

COG function: function code J; 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S4 RNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787524, Length=245, Percent_Identity=55.5102040816327, Blast_Score=265, Evalue=9e-72,
Organism=Escherichia coli, GI1790453, Length=251, Percent_Identity=30.2788844621514, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1788510, Length=218, Percent_Identity=29.3577981651376, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI87081838, Length=192, Percent_Identity=34.375, Blast_Score=83, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR006145
- InterPro:   IPR000748
- InterPro:   IPR018496
- InterPro:   IPR002942 [H]

Pfam domain/function: PF00849 PseudoU_synth_2; PF01479 S4 [H]

EC number: NA

Molecular weight: Translated: 66315; Mature: 66184

Theoretical pI: Translated: 11.52; Mature: 11.52

Prosite motif: PS50889 S4 ; PS00583 PFKB_KINASES_1 ; PS01149 PSI_RSU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHTHDTDSSESERAVPSARADETRTTQASAGEGERPAQTTEADGEDRPRRGLRRGPRSL
CCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCHHHH
IARRRAGAKTKGAEGAAAQEAPVVGEAPPDGEVVAQVRMPRKDAGAKGQGSRRNAGGARR
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHCCCCCCCCCCCCCCCCC
EGAPREGAAREGAPREGQRERQPREGQPREGGQRQNRRGGEAPAVATEAGQDDLFSYVTS
CCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCHHHHCCCCCCCCEECCCCHHHHHHHHHC
PAFDADNSATGGVRAPMLRRGKPVAPKRVLAADDDAPKLHKVLAEAGMGSRRDMEELIVA
CCCCCCCCCCCCCCCHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCHHHHHHH
GRVSVNGEPAHIGQRIMPTDQVRINGKPVKRKLASKPPRVLLYHKPTGEIVSHADPEGRP
CCEECCCCHHHHCCCCCCCCEEEECCCHHHHHHHCCCCEEEEEECCCCHHHHCCCCCCCC
SVFDKLPPMKTAKWLAVGRLDFNTEGLLMLTTSGDLANRFMHPRYSVEREYAVRVVGELA
HHHHCCCCCCCCCEEEEEEEEECCCCEEEEECCCHHHHHHCCCCHHHHHHHHHHHHHHHH
EGMRQKLLHGVELDDGPANFLRIRDGGGEGTNHWYHVALAEGRNREVRRMFEAAGLMVSR
HHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHH
LIRTRHGPISLPKGLKRGRWEELEDNQVRALMASVGLKAPTEERGSRNAAPERKQPDPMQ
HHHHCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCHHH
TSMGFINREPVLMSHGRFDQQPPRGQGRRGGAAGGGFAGGAGAGFGGGYGNRGAGRSAGG
HHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
FGGPMGAGGGAGGPRGGREVDGNRAPSGNGNRAAGGGKRVGGAGAGANPGNGGNNRGPAG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NRGGNANRAGGGNASPGGANRGGGAPRGRSRGR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
THTHDTDSSESERAVPSARADETRTTQASAGEGERPAQTTEADGEDRPRRGLRRGPRSL
CCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCHHHH
IARRRAGAKTKGAEGAAAQEAPVVGEAPPDGEVVAQVRMPRKDAGAKGQGSRRNAGGARR
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHCCCCCCCCCCCCCCCCC
EGAPREGAAREGAPREGQRERQPREGQPREGGQRQNRRGGEAPAVATEAGQDDLFSYVTS
CCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCHHHHCCCCCCCCEECCCCHHHHHHHHHC
PAFDADNSATGGVRAPMLRRGKPVAPKRVLAADDDAPKLHKVLAEAGMGSRRDMEELIVA
CCCCCCCCCCCCCCCHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCHHHHHHH
GRVSVNGEPAHIGQRIMPTDQVRINGKPVKRKLASKPPRVLLYHKPTGEIVSHADPEGRP
CCEECCCCHHHHCCCCCCCCEEEECCCHHHHHHHCCCCEEEEEECCCCHHHHCCCCCCCC
SVFDKLPPMKTAKWLAVGRLDFNTEGLLMLTTSGDLANRFMHPRYSVEREYAVRVVGELA
HHHHCCCCCCCCCEEEEEEEEECCCCEEEEECCCHHHHHHCCCCHHHHHHHHHHHHHHHH
EGMRQKLLHGVELDDGPANFLRIRDGGGEGTNHWYHVALAEGRNREVRRMFEAAGLMVSR
HHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHH
LIRTRHGPISLPKGLKRGRWEELEDNQVRALMASVGLKAPTEERGSRNAAPERKQPDPMQ
HHHHCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCHHH
TSMGFINREPVLMSHGRFDQQPPRGQGRRGGAAGGGFAGGAGAGFGGGYGNRGAGRSAGG
HHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
FGGPMGAGGGAGGPRGGREVDGNRAPSGNGNRAAGGGKRVGGAGAGANPGNGGNNRGPAG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NRGGNANRAGGGNASPGGANRGGGAPRGRSRGR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]