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The map label for this gene is astE

Identifier: 91782904

GI number: 91782904

Start: 1700008

End: 1701036

Strand: Direct

Name: astE

Synonym: Bxe_A2918

Alternate gene names: 91782904

Gene position: 1700008-1701036 (Clockwise)

Preceding gene: 91782903

Following gene: 91782905

Centisome position: 34.72

GC content: 65.89

Gene sequence:

>1029_bases
ATGCCGGTTTCGCTGCTCGACGATTTCCTCGCTTATACGCTGGCCGGTACGCGGCCGGCCGCGAGCGAAGCACAGGGCAC
GTGTGCCGGCGGCGTGCGCTGGTCGTGGCTGGACGACGGCGTATTGCTGATGGAACCGGCTGTGCAGGAAGAGGGCATGC
GCAGTGTGCTCGTCTCCGCCGGCGTGCATGGCGACGAAACCGCGCCGATCGAACTGCTCGCGTTTCTCGTGCGCGACATC
GCGCATGGCACCGCGGCGTTGACCGGCCGCCTGCTGGTGATTCTCGGCAACGTCGACGCAATGCGCGACGCGTGCCGTTA
TCGCGACGACGATCTGAACCGGCTTTTCAGCGGCCGTCATCTGCAACTGCCGCAGAGCCACGAGGCGCCGCGTGCGGCGG
CGCTGGAACGGGCCGCCACGCGGTTTTTCGCGGCGGCGCCAGACAATCCCGGCGCGCGCTGGCATATCGACATGCACACG
GCCATCCGCGCGTCCGCCTTCGAGCAGTTCGCGTTACTGCCGCACACCGGCAAGCCGTTTTCGCGTGCGATGTTCGAGTG
GCTCGGCGAGGCGCGCATCAGTGCGGTGCTGTTGCACACCACCAGGGGCAACACGTATTCGCATTTCACCGCGCAGGCAT
GTGGCGCGCTGGCTTGCACGCTGGAACTCGGCAAGGTGCGTCCGTTCGGGCAGAACGATCTGACGCGTTTCGCCGGCGCC
GATCATGCGGTGCGGCACCTGCTGGCCGGCATGCGCGGCGAGGTGCGCGCGCCTATGCCGAGGGCGTTTACGGTAATCGA
CCAGATCACCAGGCAGAGCGAAGCATTCGAATTGCTGGTCGCGCCCGATGTCGCGAATTTCACGCCGTTCGCAAAAGACA
CGGTGCTCGCACGCGATGGCGACTATCGCTATGTCGTGCGTCACGACGAGGAGCGTCTCGTGTTTCCGAACGCGACGGTC
AAGCCCGGTTTGCGCGCCGGCCTGATGGTCATCGAAACGACGCAGGACACGCTCTCGAAGCTCGTGTAG

Upstream 100 bases:

>100_bases
ACCGACCCGCATCTGCTCGCCGAGTCGCGCACCGCGCTCGACGAACTGACGCAGATTCTCGGCCTGGGCTCGCTGTATGA
CTTCCAGCGCTGAGGGCAGC

Downstream 100 bases:

>100_bases
TCCACGCAGGAACCCGCGACCGTGCGCGCGGGTTTGCCTGAACGCGACATTTATTTACACCTTCCCACCTACGGCTCACG
GCGCTCGCTCCACGACGCGC

Product: succinylglutamate desuccinylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MPVSLLDDFLAYTLAGTRPAASEAQGTCAGGVRWSWLDDGVLLMEPAVQEEGMRSVLVSAGVHGDETAPIELLAFLVRDI
AHGTAALTGRLLVILGNVDAMRDACRYRDDDLNRLFSGRHLQLPQSHEAPRAAALERAATRFFAAAPDNPGARWHIDMHT
AIRASAFEQFALLPHTGKPFSRAMFEWLGEARISAVLLHTTRGNTYSHFTAQACGALACTLELGKVRPFGQNDLTRFAGA
DHAVRHLLAGMRGEVRAPMPRAFTVIDQITRQSEAFELLVAPDVANFTPFAKDTVLARDGDYRYVVRHDEERLVFPNATV
KPGLRAGLMVIETTQDTLSKLV

Sequences:

>Translated_342_residues
MPVSLLDDFLAYTLAGTRPAASEAQGTCAGGVRWSWLDDGVLLMEPAVQEEGMRSVLVSAGVHGDETAPIELLAFLVRDI
AHGTAALTGRLLVILGNVDAMRDACRYRDDDLNRLFSGRHLQLPQSHEAPRAAALERAATRFFAAAPDNPGARWHIDMHT
AIRASAFEQFALLPHTGKPFSRAMFEWLGEARISAVLLHTTRGNTYSHFTAQACGALACTLELGKVRPFGQNDLTRFAGA
DHAVRHLLAGMRGEVRAPMPRAFTVIDQITRQSEAFELLVAPDVANFTPFAKDTVLARDGDYRYVVRHDEERLVFPNATV
KPGLRAGLMVIETTQDTLSKLV
>Mature_341_residues
PVSLLDDFLAYTLAGTRPAASEAQGTCAGGVRWSWLDDGVLLMEPAVQEEGMRSVLVSAGVHGDETAPIELLAFLVRDIA
HGTAALTGRLLVILGNVDAMRDACRYRDDDLNRLFSGRHLQLPQSHEAPRAAALERAATRFFAAAPDNPGARWHIDMHTA
IRASAFEQFALLPHTGKPFSRAMFEWLGEARISAVLLHTTRGNTYSHFTAQACGALACTLELGKVRPFGQNDLTRFAGAD
HAVRHLLAGMRGEVRAPMPRAFTVIDQITRQSEAFELLVAPDVANFTPFAKDTVLARDGDYRYVVRHDEERLVFPNATVK
PGLRAGLMVIETTQDTLSKLV

Specific function: Transforms N(2)-succinylglutamate into succinate and glutamate

COG id: COG2988

COG function: function code E; Succinylglutamate desuccinylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily

Homologues:

Organism=Escherichia coli, GI1788040, Length=326, Percent_Identity=46.6257668711656, Blast_Score=284, Evalue=5e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ASTE_BURXL (Q141D1)

Other databases:

- EMBL:   CP000270
- RefSeq:   YP_558110.1
- ProteinModelPortal:   Q141D1
- SMR:   Q141D1
- GeneID:   4004451
- GenomeReviews:   CP000270_GR
- KEGG:   bxe:Bxe_A2918
- HOGENOM:   HBG298271
- OMA:   RWRWLGH
- ProtClustDB:   PRK05324
- HAMAP:   MF_00767
- InterPro:   IPR007036
- InterPro:   IPR016681
- PIRSF:   PIRSF017020
- TIGRFAMs:   TIGR03242

Pfam domain/function: PF04952 AstE_AspA

EC number: =3.5.1.96

Molecular weight: Translated: 37411; Mature: 37280

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: PS00024 HEMOPEXIN

Important sites: ACT_SITE 222-222

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVSLLDDFLAYTLAGTRPAASEAQGTCAGGVRWSWLDDGVLLMEPAVQEEGMRSVLVSA
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCEEEECCCHHHHHHHHHHHHC
GVHGDETAPIELLAFLVRDIAHGTAALTGRLLVILGNVDAMRDACRYRDDDLNRLFSGRH
CCCCCCCCHHHHHHHHHHHHHCCHHHHHCEEEEEECCCHHHHHHHHCCCCHHHHHHCCCC
LQLPQSHEAPRAAALERAATRFFAAAPDNPGARWHIDMHTAIRASAFEQFALLPHTGKPF
CCCCCCCCCHHHHHHHHHHHHHEEECCCCCCCEEEEEHHHHHHHHHHHHHEECCCCCCHH
SRAMFEWLGEARISAVLLHTTRGNTYSHFTAQACGALACTLELGKVRPFGQNDLTRFAGA
HHHHHHHHHHHHEEEEEEEECCCCCCHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHCCC
DHAVRHLLAGMRGEVRAPMPRAFTVIDQITRQSEAFELLVAPDVANFTPFAKDTVLARDG
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEEEEECC
DYRYVVRHDEERLVFPNATVKPGLRAGLMVIETTQDTLSKLV
CEEEEEEECCCEEECCCCCCCCCCHHCEEEEEECHHHHHHCC
>Mature Secondary Structure 
PVSLLDDFLAYTLAGTRPAASEAQGTCAGGVRWSWLDDGVLLMEPAVQEEGMRSVLVSA
CHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCEEEECCCHHHHHHHHHHHHC
GVHGDETAPIELLAFLVRDIAHGTAALTGRLLVILGNVDAMRDACRYRDDDLNRLFSGRH
CCCCCCCCHHHHHHHHHHHHHCCHHHHHCEEEEEECCCHHHHHHHHCCCCHHHHHHCCCC
LQLPQSHEAPRAAALERAATRFFAAAPDNPGARWHIDMHTAIRASAFEQFALLPHTGKPF
CCCCCCCCCHHHHHHHHHHHHHEEECCCCCCCEEEEEHHHHHHHHHHHHHEECCCCCCHH
SRAMFEWLGEARISAVLLHTTRGNTYSHFTAQACGALACTLELGKVRPFGQNDLTRFAGA
HHHHHHHHHHHHEEEEEEEECCCCCCHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHCCC
DHAVRHLLAGMRGEVRAPMPRAFTVIDQITRQSEAFELLVAPDVANFTPFAKDTVLARDG
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEEEEECC
DYRYVVRHDEERLVFPNATVKPGLRAGLMVIETTQDTLSKLV
CEEEEEEECCCEEECCCCCCCCCCHHCEEEEEECHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA