BacMap

Definition	Burkholderia xenovorans LB400 chromosome 1, complete sequence.
Accession	NC_007951
Length	4,895,836

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The map label for this gene is astD [H]

Identifier: 91782902

GI number: 91782902

Start: 1697181

End: 1698650

Strand: Direct

Name: astD [H]

Synonym: Bxe_A2920

Alternate gene names: 91782902

Gene position: 1697181-1698650 (Clockwise)

Preceding gene: 91782901

Following gene: 91782903

Centisome position: 34.67

GC content: 66.67

Gene sequence:

>1470_bases
ATGATCATGAGCGAGCTTTTCATCGGCGGCGAATGGGCCGCCGGCACAGGACCCGCATTCGCGTCGCGCAACCCGGGCAC
GGGCGCGGCGGTGTGGGAAGGCAACAGCGCGTCGGCTGACGACGTGGACCGCGCGGTGCGCAGCGCGCGCCGTGCGTTCG
CCGCCTGGTCGGCGTCGAGTGTCGACGAACGTTGCGCCGTGGTGCGTCGCTTCGCCGCGCTCGTGACCGAACGCAAGGAA
GCGCTGGCCGAAGCGATCGGCCGCGAAACCGGCAAGCCGTTGTGGGAAGCGCGCACGGAAGCCGCTTCGATGGCGGCCAA
GGTCGAGATTTCGATTCAGGCCTATAACGAACGTACTGGCGAGAAGCGCTCGGCAATGGCGGACGGCACGGCCGTGTTGA
GGCATCGGCCGCATGGCGTGGTGGCCGTGTTCGGGCCGTATAACTTTCCTGGGCATCTGCCGAACGGCCATATCGTGCCG
GCGCTGATCGCGGGCAATGCGGTCGTGTTCAAGCCGTCGGAACTCGCGCCCGGCGTGGCCGCGCTCACCGTGCAGATCTG
GCGCGACGCCGGTTTGCCGGCAGGCGTGCTGAACCTCGTGCAGGGCGAGAAAGACACGGGCATTGCGCTGGCGAATCACC
GGCAGATCGACGGCCTCTTCTTCACAGGTAGTTCGGATACCGGAACATTGCTGCACAAGCAGTTCGGCGGCCGCCCCGAG
ATCGTGCTGGCGCTGGAAATGGGCGGCAACAATCCGCTCGTGATCGGGCCGGTGGCCGATGTCGATGCCGCCGTGCATCA
CACGATCCAGTCAGCGTTTCTGTCGGCGGGGCAGCGTTGCACGTGTGCGCGCCGCATCTTCGTGCCGAACGACGCAGCGG
GCGATCGCTTCCTGGAGCGCTTCACCGAGGTCACCTCGCGCATCACTGTCGGCGAATACAACGCCGATCCGCAACCGTTC
ATGGGCGCGGTGATTTCGGTGCGCGCGGCGTCGCGTCTCGTCGCCGCGCAGGAACGCTTGCTGGCTGACGGCGCCAAAGC
ATTGCTGAAGATGGAGCAACGCGATCCGAAGCTCGGCTTCGTCACGCCCGCGATTCTCGACGTCACGAACGTGGCGAATC
GGCCGGACGAAGAACACTTCGGTCCTTTGGCGCAGATCATCCGCTACGGCAGCTTTAACGAAGCGCTGGAACAGGCCAAC
GACACCGAGTTCGGCCTCTCGGCGGGCCTCCTCGCCGACGACGAAGCGCTCTGGGCGCACTTCCAGCGCACCATCCGCGC
GGGCATCGTCAACTGGAACCGGCCGACCAACGGCGCCTCGTCGGGCGCGCCGTTCGGCGGTCCGGGCCGCTCGGGCAATC
ACCGGCCGAGCGCGTACTACGCCGCCGACTACTGCGCGTTCCCGATGGCTTCCGTCGAAAGCGCGCAACTGCAAATGCCC
GCGAGCGTCTCGCCGGGCCTTCAATTCTAA

Upstream 100 bases:

>100_bases
CGCAGGACGGTGTGTTCCGCCTCAGCGCGGCCGAGGCCTCGGCACTCGACGTCGAGGCGGGCGACCTCGTGCGCGTGCTG
CCGCAGAAACACAAACAGGG

Downstream 100 bases:

>100_bases
GGATCGACGATGCAAGCCACTGAAGCCAATTTCGACGGCCTGGTCGGCCCGACCCACAACTACGCGGGGCTCTCGTTCGG
CAACGTCGCGTCGCAGAACA

Product: succinylglutamic semialdehyde dehydrogenase

Products: NA

Alternate protein names: Succinylglutamic semialdehyde dehydrogenase; SGSD [H]

Number of amino acids: Translated: 489; Mature: 489

Protein sequence:

>489_residues
MIMSELFIGGEWAAGTGPAFASRNPGTGAAVWEGNSASADDVDRAVRSARRAFAAWSASSVDERCAVVRRFAALVTERKE
ALAEAIGRETGKPLWEARTEAASMAAKVEISIQAYNERTGEKRSAMADGTAVLRHRPHGVVAVFGPYNFPGHLPNGHIVP
ALIAGNAVVFKPSELAPGVAALTVQIWRDAGLPAGVLNLVQGEKDTGIALANHRQIDGLFFTGSSDTGTLLHKQFGGRPE
IVLALEMGGNNPLVIGPVADVDAAVHHTIQSAFLSAGQRCTCARRIFVPNDAAGDRFLERFTEVTSRITVGEYNADPQPF
MGAVISVRAASRLVAAQERLLADGAKALLKMEQRDPKLGFVTPAILDVTNVANRPDEEHFGPLAQIIRYGSFNEALEQAN
DTEFGLSAGLLADDEALWAHFQRTIRAGIVNWNRPTNGASSGAPFGGPGRSGNHRPSAYYAADYCAFPMASVESAQLQMP
ASVSPGLQF

Sequences:

>Translated_489_residues
MIMSELFIGGEWAAGTGPAFASRNPGTGAAVWEGNSASADDVDRAVRSARRAFAAWSASSVDERCAVVRRFAALVTERKE
ALAEAIGRETGKPLWEARTEAASMAAKVEISIQAYNERTGEKRSAMADGTAVLRHRPHGVVAVFGPYNFPGHLPNGHIVP
ALIAGNAVVFKPSELAPGVAALTVQIWRDAGLPAGVLNLVQGEKDTGIALANHRQIDGLFFTGSSDTGTLLHKQFGGRPE
IVLALEMGGNNPLVIGPVADVDAAVHHTIQSAFLSAGQRCTCARRIFVPNDAAGDRFLERFTEVTSRITVGEYNADPQPF
MGAVISVRAASRLVAAQERLLADGAKALLKMEQRDPKLGFVTPAILDVTNVANRPDEEHFGPLAQIIRYGSFNEALEQAN
DTEFGLSAGLLADDEALWAHFQRTIRAGIVNWNRPTNGASSGAPFGGPGRSGNHRPSAYYAADYCAFPMASVESAQLQMP
ASVSPGLQF
>Mature_489_residues
MIMSELFIGGEWAAGTGPAFASRNPGTGAAVWEGNSASADDVDRAVRSARRAFAAWSASSVDERCAVVRRFAALVTERKE
ALAEAIGRETGKPLWEARTEAASMAAKVEISIQAYNERTGEKRSAMADGTAVLRHRPHGVVAVFGPYNFPGHLPNGHIVP
ALIAGNAVVFKPSELAPGVAALTVQIWRDAGLPAGVLNLVQGEKDTGIALANHRQIDGLFFTGSSDTGTLLHKQFGGRPE
IVLALEMGGNNPLVIGPVADVDAAVHHTIQSAFLSAGQRCTCARRIFVPNDAAGDRFLERFTEVTSRITVGEYNADPQPF
MGAVISVRAASRLVAAQERLLADGAKALLKMEQRDPKLGFVTPAILDVTNVANRPDEEHFGPLAQIIRYGSFNEALEQAN
DTEFGLSAGLLADDEALWAHFQRTIRAGIVNWNRPTNGASSGAPFGGPGRSGNHRPSAYYAADYCAFPMASVESAQLQMP
ASVSPGLQF

Specific function: Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate [H]

COG id: COG1012

COG function: function code C; NAD-dependent aldehyde dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family. AstD subfamily [H]

Homologues:

Organism=Homo sapiens, GI25777724, Length=465, Percent_Identity=32.258064516129, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI25777730, Length=463, Percent_Identity=31.7494600431965, Blast_Score=198, Evalue=9e-51,
Organism=Homo sapiens, GI153266822, Length=480, Percent_Identity=30, Blast_Score=197, Evalue=3e-50,
Organism=Homo sapiens, GI115387104, Length=492, Percent_Identity=31.7073170731707, Blast_Score=196, Evalue=6e-50,
Organism=Homo sapiens, GI12007648, Length=476, Percent_Identity=29.8319327731092, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI21361176, Length=482, Percent_Identity=30.2904564315353, Blast_Score=191, Evalue=2e-48,
Organism=Homo sapiens, GI25777732, Length=468, Percent_Identity=28.4188034188034, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI25777728, Length=402, Percent_Identity=31.8407960199005, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI25777726, Length=464, Percent_Identity=29.0948275862069, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI11095441, Length=444, Percent_Identity=27.4774774774775, Blast_Score=159, Evalue=7e-39,
Organism=Homo sapiens, GI4507229, Length=472, Percent_Identity=29.4491525423729, Blast_Score=156, Evalue=4e-38,
Organism=Homo sapiens, GI188035924, Length=466, Percent_Identity=26.1802575107296, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI310128093, Length=466, Percent_Identity=26.1802575107296, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI310128103, Length=466, Percent_Identity=26.1802575107296, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI25777721, Length=485, Percent_Identity=28.659793814433, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI21614513, Length=472, Percent_Identity=28.3898305084746, Blast_Score=146, Evalue=4e-35,
Organism=Homo sapiens, GI238814322, Length=468, Percent_Identity=27.7777777777778, Blast_Score=143, Evalue=4e-34,
Organism=Homo sapiens, GI310128091, Length=467, Percent_Identity=25.6959314775161, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI301500698, Length=473, Percent_Identity=26.215644820296, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI25952152, Length=277, Percent_Identity=31.0469314079422, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI4502043, Length=437, Percent_Identity=26.7734553775744, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI238814371, Length=437, Percent_Identity=26.7734553775744, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI238859541, Length=437, Percent_Identity=28.1464530892449, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI25777736, Length=437, Percent_Identity=28.1464530892449, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI25777734, Length=437, Percent_Identity=28.1464530892449, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI310128089, Length=298, Percent_Identity=28.1879194630872, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI206597441, Length=419, Percent_Identity=25.5369928400955, Blast_Score=109, Evalue=7e-24,
Organism=Homo sapiens, GI206597439, Length=419, Percent_Identity=25.5369928400955, Blast_Score=109, Evalue=7e-24,
Organism=Homo sapiens, GI22907049, Length=419, Percent_Identity=25.5369928400955, Blast_Score=109, Evalue=7e-24,
Organism=Homo sapiens, GI71773324, Length=431, Percent_Identity=25.754060324826, Blast_Score=106, Evalue=6e-23,
Organism=Homo sapiens, GI310128095, Length=313, Percent_Identity=27.1565495207668, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI310128087, Length=288, Percent_Identity=26.3888888888889, Blast_Score=102, Evalue=9e-22,
Organism=Homo sapiens, GI4557303, Length=421, Percent_Identity=22.8028503562945, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI73466520, Length=417, Percent_Identity=23.021582733813, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI73695881, Length=353, Percent_Identity=26.9121813031161, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI73695879, Length=353, Percent_Identity=26.9121813031161, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI310128097, Length=262, Percent_Identity=28.2442748091603, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI310128099, Length=236, Percent_Identity=24.1525423728814, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI310128101, Length=232, Percent_Identity=25, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI1788042, Length=484, Percent_Identity=56.198347107438, Blast_Score=559, Evalue=1e-160,
Organism=Escherichia coli, GI1789015, Length=469, Percent_Identity=33.0490405117271, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI1787558, Length=473, Percent_Identity=32.76955602537, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI1786504, Length=488, Percent_Identity=30.327868852459, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI87082295, Length=472, Percent_Identity=31.1440677966102, Blast_Score=171, Evalue=9e-44,
Organism=Escherichia coli, GI87081926, Length=446, Percent_Identity=28.9237668161435, Blast_Score=162, Evalue=5e-41,
Organism=Escherichia coli, GI1787684, Length=441, Percent_Identity=27.891156462585, Blast_Score=159, Evalue=4e-40,
Organism=Escherichia coli, GI1787250, Length=436, Percent_Identity=30.2752293577982, Blast_Score=155, Evalue=5e-39,
Organism=Escherichia coli, GI87081896, Length=473, Percent_Identity=28.7526427061311, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1787715, Length=475, Percent_Identity=27.7894736842105, Blast_Score=133, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI25143874, Length=439, Percent_Identity=30.751708428246, Blast_Score=187, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI25143876, Length=439, Percent_Identity=30.751708428246, Blast_Score=187, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17562198, Length=485, Percent_Identity=29.8969072164948, Blast_Score=184, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI71995606, Length=451, Percent_Identity=30.5986696230599, Blast_Score=179, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI17551164, Length=466, Percent_Identity=29.6137339055794, Blast_Score=178, Evalue=5e-45,
Organism=Caenorhabditis elegans, GI25144435, Length=495, Percent_Identity=28.6868686868687, Blast_Score=177, Evalue=8e-45,
Organism=Caenorhabditis elegans, GI17534119, Length=466, Percent_Identity=27.8969957081545, Blast_Score=174, Evalue=9e-44,
Organism=Caenorhabditis elegans, GI71995613, Length=405, Percent_Identity=30.8641975308642, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI133930964, Length=460, Percent_Identity=28.9130434782609, Blast_Score=164, Evalue=8e-41,
Organism=Caenorhabditis elegans, GI32564736, Length=434, Percent_Identity=28.8018433179723, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI115534176, Length=470, Percent_Identity=28.0851063829787, Blast_Score=155, Evalue=5e-38,
Organism=Caenorhabditis elegans, GI71986308, Length=444, Percent_Identity=26.5765765765766, Blast_Score=129, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI17534447, Length=444, Percent_Identity=25.6756756756757, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI32566756, Length=430, Percent_Identity=25.3488372093023, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI25146394, Length=430, Percent_Identity=25.3488372093023, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI25146391, Length=430, Percent_Identity=25.3488372093023, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI115532534, Length=335, Percent_Identity=27.7611940298507, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI32564151, Length=411, Percent_Identity=25.3041362530414, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17564084, Length=432, Percent_Identity=25.462962962963, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71990744, Length=295, Percent_Identity=24.0677966101695, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323821, Length=476, Percent_Identity=29.4117647058824, Blast_Score=184, Evalue=2e-47,
Organism=Saccharomyces cerevisiae, GI6320917, Length=455, Percent_Identity=30.1098901098901, Blast_Score=184, Evalue=3e-47,
Organism=Saccharomyces cerevisiae, GI6323822, Length=468, Percent_Identity=29.7008547008547, Blast_Score=181, Evalue=3e-46,
Organism=Saccharomyces cerevisiae, GI6319478, Length=474, Percent_Identity=28.6919831223629, Blast_Score=180, Evalue=5e-46,
Organism=Saccharomyces cerevisiae, GI6324950, Length=452, Percent_Identity=28.3185840707965, Blast_Score=170, Evalue=4e-43,
Organism=Saccharomyces cerevisiae, GI6325196, Length=457, Percent_Identity=28.0087527352298, Blast_Score=159, Evalue=8e-40,
Organism=Saccharomyces cerevisiae, GI6321826, Length=469, Percent_Identity=26.865671641791, Blast_Score=115, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6321828, Length=458, Percent_Identity=24.235807860262, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6323757, Length=334, Percent_Identity=25.4491017964072, Blast_Score=77, Evalue=5e-15,
Organism=Drosophila melanogaster, GI20129399, Length=492, Percent_Identity=31.3008130081301, Blast_Score=204, Evalue=1e-52,
Organism=Drosophila melanogaster, GI281362580, Length=474, Percent_Identity=28.9029535864979, Blast_Score=176, Evalue=4e-44,
Organism=Drosophila melanogaster, GI62472918, Length=474, Percent_Identity=28.9029535864979, Blast_Score=176, Evalue=4e-44,
Organism=Drosophila melanogaster, GI62472926, Length=474, Percent_Identity=28.9029535864979, Blast_Score=176, Evalue=4e-44,
Organism=Drosophila melanogaster, GI62472936, Length=474, Percent_Identity=28.9029535864979, Blast_Score=176, Evalue=4e-44,
Organism=Drosophila melanogaster, GI21356737, Length=474, Percent_Identity=28.9029535864979, Blast_Score=176, Evalue=4e-44,
Organism=Drosophila melanogaster, GI24650465, Length=466, Percent_Identity=28.9699570815451, Blast_Score=165, Evalue=8e-41,
Organism=Drosophila melanogaster, GI24585660, Length=468, Percent_Identity=29.4871794871795, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24666674, Length=476, Percent_Identity=28.3613445378151, Blast_Score=155, Evalue=7e-38,
Organism=Drosophila melanogaster, GI24638878, Length=439, Percent_Identity=28.0182232346241, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24638876, Length=439, Percent_Identity=28.0182232346241, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI24668425, Length=441, Percent_Identity=27.891156462585, Blast_Score=115, Evalue=6e-26,
Organism=Drosophila melanogaster, GI24668417, Length=441, Percent_Identity=27.891156462585, Blast_Score=115, Evalue=6e-26,
Organism=Drosophila melanogaster, GI24668413, Length=441, Percent_Identity=27.891156462585, Blast_Score=115, Evalue=6e-26,
Organism=Drosophila melanogaster, GI28571806, Length=434, Percent_Identity=25.8064516129032, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI28571802, Length=434, Percent_Identity=25.8064516129032, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI28571800, Length=434, Percent_Identity=25.8064516129032, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI28571798, Length=434, Percent_Identity=25.8064516129032, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI28571796, Length=434, Percent_Identity=25.8064516129032, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI28571794, Length=434, Percent_Identity=25.8064516129032, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI28574525, Length=444, Percent_Identity=26.3513513513513, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI45552499, Length=428, Percent_Identity=25.2336448598131, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI281360303, Length=428, Percent_Identity=25.2336448598131, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI281360301, Length=428, Percent_Identity=25, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI281360299, Length=428, Percent_Identity=25, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI281360297, Length=428, Percent_Identity=25, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI281360295, Length=428, Percent_Identity=25, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24586250, Length=428, Percent_Identity=25, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI281360293, Length=250, Percent_Identity=25.2, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR017649 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.2.1.71 [H]

Molecular weight: Translated: 51950; Mature: 51950

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU ; PS00070 ALDEHYDE_DEHYDR_CYS ; PS00177 TOPOISOMERASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIMSELFIGGEWAAGTGPAFASRNPGTGAAVWEGNSASADDVDRAVRSARRAFAAWSASS
CCHHHEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCC
VDERCAVVRRFAALVTERKEALAEAIGRETGKPLWEARTEAASMAAKVEISIQAYNERTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEEEEEEEEECCCCCC
EKRSAMADGTAVLRHRPHGVVAVFGPYNFPGHLPNGHIVPALIAGNAVVFKPSELAPGVA
HHHHHHHCCHHHEEECCCCEEEEECCCCCCCCCCCCCEEEEEEECCEEEECCHHHCCCHH
ALTVQIWRDAGLPAGVLNLVQGEKDTGIALANHRQIDGLFFTGSSDTGTLLHKQFGGRPE
HHEEHHHHCCCCCHHHHHHHCCCCCCCEEEECCCEECEEEEECCCCCCHHHHHHHCCCCC
IVLALEMGGNNPLVIGPVADVDAAVHHTIQSAFLSAGQRCTCARRIFVPNDAAGDRFLER
EEEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHH
FTEVTSRITVGEYNADPQPFMGAVISVRAASRLVAAQERLLADGAKALLKMEQRDPKLGF
HHHHHHCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
VTPAILDVTNVANRPDEEHFGPLAQIIRYGSFNEALEQANDTEFGLSAGLLADDEALWAH
CCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHH
FQRTIRAGIVNWNRPTNGASSGAPFGGPGRSGNHRPSAYYAADYCAFPMASVESAQLQMP
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHCCCCCCCCHHEECC
ASVSPGLQF
CCCCCCCCC
>Mature Secondary Structure
MIMSELFIGGEWAAGTGPAFASRNPGTGAAVWEGNSASADDVDRAVRSARRAFAAWSASS
CCHHHEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCC
VDERCAVVRRFAALVTERKEALAEAIGRETGKPLWEARTEAASMAAKVEISIQAYNERTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEEEEEEEEECCCCCC
EKRSAMADGTAVLRHRPHGVVAVFGPYNFPGHLPNGHIVPALIAGNAVVFKPSELAPGVA
HHHHHHHCCHHHEEECCCCEEEEECCCCCCCCCCCCCEEEEEEECCEEEECCHHHCCCHH
ALTVQIWRDAGLPAGVLNLVQGEKDTGIALANHRQIDGLFFTGSSDTGTLLHKQFGGRPE
HHEEHHHHCCCCCHHHHHHHCCCCCCCEEEECCCEECEEEEECCCCCCHHHHHHHCCCCC
IVLALEMGGNNPLVIGPVADVDAAVHHTIQSAFLSAGQRCTCARRIFVPNDAAGDRFLER
EEEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHH
FTEVTSRITVGEYNADPQPFMGAVISVRAASRLVAAQERLLADGAKALLKMEQRDPKLGF
HHHHHHCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
VTPAILDVTNVANRPDEEHFGPLAQIIRYGSFNEALEQANDTEFGLSAGLLADDEALWAH
CCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHH
FQRTIRAGIVNWNRPTNGASSGAPFGGPGRSGNHRPSAYYAADYCAFPMASVESAQLQMP
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHCCCCCCCCHHEECC
ASVSPGLQF
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA