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The map label for this gene is mmgC [H]

Identifier: 91782635

GI number: 91782635

Start: 1407110

End: 1408237

Strand: Direct

Name: mmgC [H]

Synonym: Bxe_A3191

Alternate gene names: 91782635

Gene position: 1407110-1408237 (Clockwise)

Preceding gene: 91782634

Following gene: 91782636

Centisome position: 28.74

GC content: 65.6

Gene sequence:

>1128_bases
ATGGACTTCACTTTCAACGAAGAACAGCAGCAATTTGCGGATGCGTTGCGCCGCTATCTGGACAGGAGCTATGGGTTCGA
AGCGCGCCAGGCGATCGTGCGATCTGAACCCGGTGTATCCGATGCGCATTGGGCCGCGTTTGCCGAACTGGGCCTGACTG
CGTTGCCGGTGCCGGAAGCGCAAGGCGGTTTCAACGGCGGCCCGATCGACATGCTTGTCGTCATGCAGGAACTCGGCCGC
GCGCTGGTCGTCGAGCCTTATTGGGCGACGGCGGTCGGCATCGAGGCGTTGCGCCTCGCGGGTAGCGAACAAGGCGAAGA
CGCGTCGCTGCTCGAACGTGCGGCTCGGGGCGAGATCAAACTGGCTGTGGCCTTTCACGAACCCCACGCTCGCTACGACC
TTTTCTCGATTGAGACAACCGCGAGCGGGCAAGGCGGACAGCACACATTGACCGGCACCAAGTCGGTCGTACTGCACGGT
GCGCAGGCCGACCACTGGATCGTGCCGGCCCGGCTGAACGGCGAGATCGCACTCTTTGTCGTGGCGCGCCATGCGGCCGG
CGTCAGCGTAACGGACTACCGCACGATCGACGGCCAGCGTGCCGCCACGCTAGAGTTCAACGGCACGCCTGCGCGCCAGC
TTGCCGGCCAACACGCTGGCGCGGCGGCGCTCGAACATATCGCCGACTACGGCACGGTGCTGCTGTGCGCCGAGGCAATC
GGCGCGCTCGACGCCTTGAACCTCGCCACGGTGGACTACACGAAGACGCGCCAGCAGTTCGGCCAGCCGATCGCGCGTTT
TCAGGCCTTGCAGCATCGCATGGTGGAGATGCTGATTCACGCCGAGCAGGCGCGTTCCGTCACGTATCTGGCCGCCATGC
GCTACACCAGCACGGACGTCGACGAACGTCGCCGCGCGGTTTCCGCCGCGAAGGCGCGGGTGGGGCAGGCCGCGCGCTTC
GTCGGCCAGCAGGCGGTCCAGTTGCATGGCGGCATGGGCGTCACGAACGAAGTAGCGGCGGCACATCTGTTCAAACGGCT
TGCCATCATCGAAACCACATTGGGCGATGTCGATCACCATCTCGCGCGGTTCGCCGCGCTGCCCGGCTTCGTCACGGCCG
AGGCGTGA

Upstream 100 bases:

>100_bases
TACTACTTCAACTTCCGCAAGACATCGATTTACGGTGGCTCGAACGAAATTCAAAAGAACATCATCGCGCAGATGATTCT
CGGACTTTGAGGAGCGGCGC

Downstream 100 bases:

>100_bases
TCAGCCGCCCGAATCGAATAAAAGGAGATACGACAATGGGTTTGAGTTACGAGGACTTGATAGTCGGCACGAGCATCGAA
ATCGGCAAGCACACGTTCAC

Product: putative pimeloyl-CoA dehydrogenase (small subunit), PimD-like

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MDFTFNEEQQQFADALRRYLDRSYGFEARQAIVRSEPGVSDAHWAAFAELGLTALPVPEAQGGFNGGPIDMLVVMQELGR
ALVVEPYWATAVGIEALRLAGSEQGEDASLLERAARGEIKLAVAFHEPHARYDLFSIETTASGQGGQHTLTGTKSVVLHG
AQADHWIVPARLNGEIALFVVARHAAGVSVTDYRTIDGQRAATLEFNGTPARQLAGQHAGAAALEHIADYGTVLLCAEAI
GALDALNLATVDYTKTRQQFGQPIARFQALQHRMVEMLIHAEQARSVTYLAAMRYTSTDVDERRRAVSAAKARVGQAARF
VGQQAVQLHGGMGVTNEVAAAHLFKRLAIIETTLGDVDHHLARFAALPGFVTAEA

Sequences:

>Translated_375_residues
MDFTFNEEQQQFADALRRYLDRSYGFEARQAIVRSEPGVSDAHWAAFAELGLTALPVPEAQGGFNGGPIDMLVVMQELGR
ALVVEPYWATAVGIEALRLAGSEQGEDASLLERAARGEIKLAVAFHEPHARYDLFSIETTASGQGGQHTLTGTKSVVLHG
AQADHWIVPARLNGEIALFVVARHAAGVSVTDYRTIDGQRAATLEFNGTPARQLAGQHAGAAALEHIADYGTVLLCAEAI
GALDALNLATVDYTKTRQQFGQPIARFQALQHRMVEMLIHAEQARSVTYLAAMRYTSTDVDERRRAVSAAKARVGQAARF
VGQQAVQLHGGMGVTNEVAAAHLFKRLAIIETTLGDVDHHLARFAALPGFVTAEA
>Mature_375_residues
MDFTFNEEQQQFADALRRYLDRSYGFEARQAIVRSEPGVSDAHWAAFAELGLTALPVPEAQGGFNGGPIDMLVVMQELGR
ALVVEPYWATAVGIEALRLAGSEQGEDASLLERAARGEIKLAVAFHEPHARYDLFSIETTASGQGGQHTLTGTKSVVLHG
AQADHWIVPARLNGEIALFVVARHAAGVSVTDYRTIDGQRAATLEFNGTPARQLAGQHAGAAALEHIADYGTVLLCAEAI
GALDALNLATVDYTKTRQQFGQPIARFQALQHRMVEMLIHAEQARSVTYLAAMRYTSTDVDERRRAVSAAKARVGQAARF
VGQQAVQLHGGMGVTNEVAAAHLFKRLAIIETTLGDVDHHLARFAALPGFVTAEA

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557235, Length=392, Percent_Identity=26.2755102040816, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI76496475, Length=392, Percent_Identity=26.2755102040816, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI226958412, Length=370, Percent_Identity=24.8648648648649, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI226958414, Length=331, Percent_Identity=25.6797583081571, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI4557233, Length=318, Percent_Identity=27.0440251572327, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI4557231, Length=384, Percent_Identity=26.5625, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI187960098, Length=384, Percent_Identity=26.5625, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI21361497, Length=390, Percent_Identity=24.3589743589744, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI4501857, Length=329, Percent_Identity=26.1398176291793, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI7656849, Length=236, Percent_Identity=26.271186440678, Blast_Score=69, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17538396, Length=369, Percent_Identity=24.6612466124661, Blast_Score=95, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17506239, Length=337, Percent_Identity=27.0029673590504, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI71985184, Length=345, Percent_Identity=26.9565217391304, Blast_Score=81, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17508101, Length=384, Percent_Identity=24.21875, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17534899, Length=319, Percent_Identity=25.0783699059561, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17569725, Length=330, Percent_Identity=25.7575757575758, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71990804, Length=260, Percent_Identity=23.0769230769231, Blast_Score=64, Evalue=9e-11,
Organism=Drosophila melanogaster, GI21355753, Length=330, Percent_Identity=27.5757575757576, Blast_Score=91, Evalue=9e-19,
Organism=Drosophila melanogaster, GI21356377, Length=321, Percent_Identity=27.1028037383178, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24646207, Length=326, Percent_Identity=27.3006134969325, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24660351, Length=326, Percent_Identity=26.0736196319018, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24666513, Length=348, Percent_Identity=25, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 40417; Mature: 40417

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFTFNEEQQQFADALRRYLDRSYGFEARQAIVRSEPGVSDAHWAAFAELGLTALPVPEA
CCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHCCCEECCCCCC
QGGFNGGPIDMLVVMQELGRALVVEPYWATAVGIEALRLAGSEQGEDASLLERAARGEIK
CCCCCCCHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCEE
LAVAFHEPHARYDLFSIETTASGQGGQHTLTGTKSVVLHGAQADHWIVPARLNGEIALFV
EEEEEECCCCCEEEEEEEEECCCCCCCEEECCCCEEEEECCCCCCEEEEEEECCCEEEEE
VARHAAGVSVTDYRTIDGQRAATLEFNGTPARQLAGQHAGAAALEHIADYGTVLLCAEAI
EEECCCCCEEECEEECCCCEEEEEEECCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
GALDALNLATVDYTKTRQQFGQPIARFQALQHRMVEMLIHAEQARSVTYLAAMRYTSTDV
HHHHHHHEEECCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
DERRRAVSAAKARVGQAARFVGQQAVQLHGGMGVTNEVAAAHLFKRLAIIETTLGDVDHH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LARFAALPGFVTAEA
HHHHHHCCCCEECCC
>Mature Secondary Structure
MDFTFNEEQQQFADALRRYLDRSYGFEARQAIVRSEPGVSDAHWAAFAELGLTALPVPEA
CCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHCCCEECCCCCC
QGGFNGGPIDMLVVMQELGRALVVEPYWATAVGIEALRLAGSEQGEDASLLERAARGEIK
CCCCCCCHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCEE
LAVAFHEPHARYDLFSIETTASGQGGQHTLTGTKSVVLHGAQADHWIVPARLNGEIALFV
EEEEEECCCCCEEEEEEEEECCCCCCCEEECCCCEEEEECCCCCCEEEEEEECCCEEEEE
VARHAAGVSVTDYRTIDGQRAATLEFNGTPARQLAGQHAGAAALEHIADYGTVLLCAEAI
EEECCCCCEEECEEECCCCEEEEEEECCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
GALDALNLATVDYTKTRQQFGQPIARFQALQHRMVEMLIHAEQARSVTYLAAMRYTSTDV
HHHHHHHEEECCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
DERRRAVSAAKARVGQAARFVGQQAVQLHGGMGVTNEVAAAHLFKRLAIIETTLGDVDHH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LARFAALPGFVTAEA
HHHHHHCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]