BacMap

Definition	Burkholderia xenovorans LB400 chromosome 1, complete sequence.
Accession	NC_007951
Length	4,895,836

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The map label for this gene is fabG [H]

Identifier: 91782571

GI number: 91782571

Start: 1338267

End: 1339046

Strand: Direct

Name: fabG [H]

Synonym: Bxe_A3257

Alternate gene names: 91782571

Gene position: 1338267-1339046 (Clockwise)

Preceding gene: 91782563

Following gene: 91782572

Centisome position: 27.33

GC content: 66.79

Gene sequence:

>780_bases
ATGGACATGGGAATCGCAGGACGCACCGCGCTGGTCTGCGCGGCCAGCAAGGGACTGGGGCGCGGCTGTGCGGAAGCGCT
CGCCGCCGAAGGCGTCGACCTGACGATCGTCGCGCGCACCGCCGAGACGCTTGAAGCGACCGCCGCGGAGATCCGCAAGC
AAAGCGGCGTGGAAGTGAAAACGGTGGCATGCGACATCACCACGCCCGAAGGCCGCGCCGCGGCGCTCGCGGCCTGTCCG
CAGCCGGACATTCTGGTCAACAACGCGGGCGGCCCGCCGCCGGGCGACTTCCGCAACTTCACGCACGAAGACTGGATCCG
CGCGCTGGAAAGCAACATGCTCACGCCGATCGAGCTGATTCGCGCGACCATCGACTCGATGAGCGCACGCGGCTATGGGC
GTATCGTCAACATCACGAGTTCGGCGGTGAAGGCGCCCATCGACGTGCTCGGTTTGTCGAACGGCGCGCGTTCGGGGCTG
ACCGGCTTCGTCGCGGGCCTCGCGCGCAAGGTTGCGCCCACCGGCGTGACCATCAACAACCTGCTGCCGGGAATTTTCGA
CACCGATCGCATTGCGGTGACCTTCGCGGCGCAGGCCAGGTCGCAGAACATTTCGGTCGACCAGGCGCGCCAGCAGCGCA
TGAAAACGATTCCCGCCGGCCGCTTCGGCAACCGTGACGAATTCGGCCGCGCCTGTGCGTTCCTGTGCAGCGTGCATGCC
GGCTACATTACCGGACAGAACTGGCTGATCGACGGCGGCGCCTATCCGGGTACGTTCTGA

Upstream 100 bases:

>100_bases
CGCGCCGGACCTGCCGCTTCGCGCGATCTCCCGAAGGAACCGCCAACCCGGCACGGCCCGGCGCTTTCTCACGACACACA
ACTTCACGAGGACACCACAG

Downstream 100 bases:

>100_bases
GCGGCACGAACCGCGGTTTCATCATCACGACAACAACGACAATCACAACGGTTTCAGGAGTCTTGCGTCATGACCACCCG
TATCGCGCTGATCGCGCACG

Product: putative 3-oxoacyl-acyl carrier protein reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MDMGIAGRTALVCAASKGLGRGCAEALAAEGVDLTIVARTAETLEATAAEIRKQSGVEVKTVACDITTPEGRAAALAACP
QPDILVNNAGGPPPGDFRNFTHEDWIRALESNMLTPIELIRATIDSMSARGYGRIVNITSSAVKAPIDVLGLSNGARSGL
TGFVAGLARKVAPTGVTINNLLPGIFDTDRIAVTFAAQARSQNISVDQARQQRMKTIPAGRFGNRDEFGRACAFLCSVHA
GYITGQNWLIDGGAYPGTF

Sequences:

>Translated_259_residues
MDMGIAGRTALVCAASKGLGRGCAEALAAEGVDLTIVARTAETLEATAAEIRKQSGVEVKTVACDITTPEGRAAALAACP
QPDILVNNAGGPPPGDFRNFTHEDWIRALESNMLTPIELIRATIDSMSARGYGRIVNITSSAVKAPIDVLGLSNGARSGL
TGFVAGLARKVAPTGVTINNLLPGIFDTDRIAVTFAAQARSQNISVDQARQQRMKTIPAGRFGNRDEFGRACAFLCSVHA
GYITGQNWLIDGGAYPGTF
>Mature_259_residues
MDMGIAGRTALVCAASKGLGRGCAEALAAEGVDLTIVARTAETLEATAAEIRKQSGVEVKTVACDITTPEGRAAALAACP
QPDILVNNAGGPPPGDFRNFTHEDWIRALESNMLTPIELIRATIDSMSARGYGRIVNITSSAVKAPIDVLGLSNGARSGL
TGFVAGLARKVAPTGVTINNLLPGIFDTDRIAVTFAAQARSQNISVDQARQQRMKTIPAGRFGNRDEFGRACAFLCSVHA
GYITGQNWLIDGGAYPGTF

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=255, Percent_Identity=28.2352941176471, Blast_Score=102, Evalue=2e-22,
Organism=Homo sapiens, GI5031737, Length=253, Percent_Identity=27.2727272727273, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI40254992, Length=249, Percent_Identity=27.710843373494, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI7705925, Length=256, Percent_Identity=26.953125, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI19923817, Length=259, Percent_Identity=26.6409266409266, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI33667109, Length=190, Percent_Identity=28.9473684210526, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI66933014, Length=211, Percent_Identity=25.1184834123223, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI4557649, Length=184, Percent_Identity=28.804347826087, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI126723750, Length=259, Percent_Identity=25.0965250965251, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI7705855, Length=183, Percent_Identity=25.1366120218579, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI126723191, Length=193, Percent_Identity=26.9430051813472, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI4503301, Length=258, Percent_Identity=25.1937984496124, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1787335, Length=259, Percent_Identity=34.7490347490347, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI87082160, Length=258, Percent_Identity=28.6821705426357, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87082100, Length=258, Percent_Identity=30.6201550387597, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1788459, Length=252, Percent_Identity=26.984126984127, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1787905, Length=256, Percent_Identity=25.390625, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1789208, Length=258, Percent_Identity=27.5193798449612, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790717, Length=255, Percent_Identity=23.921568627451, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1786812, Length=263, Percent_Identity=25.4752851711027, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560676, Length=256, Percent_Identity=28.90625, Blast_Score=113, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI17562910, Length=262, Percent_Identity=27.8625954198473, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17561402, Length=255, Percent_Identity=25.8823529411765, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI193204405, Length=267, Percent_Identity=29.2134831460674, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=262, Percent_Identity=29.0076335877863, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17559104, Length=263, Percent_Identity=28.8973384030418, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17538486, Length=265, Percent_Identity=29.4339622641509, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17562906, Length=267, Percent_Identity=28.8389513108614, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17565030, Length=259, Percent_Identity=30.5019305019305, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71994600, Length=252, Percent_Identity=26.984126984127, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=263, Percent_Identity=26.9961977186312, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17560332, Length=264, Percent_Identity=29.1666666666667, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=274, Percent_Identity=28.1021897810219, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI72000259, Length=263, Percent_Identity=27.7566539923954, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17560150, Length=262, Percent_Identity=28.6259541984733, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=265, Percent_Identity=29.4339622641509, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71994604, Length=251, Percent_Identity=27.4900398406374, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17538480, Length=268, Percent_Identity=28.7313432835821, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17563726, Length=259, Percent_Identity=26.2548262548263, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=261, Percent_Identity=27.2030651340996, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17508651, Length=249, Percent_Identity=25.3012048192771, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17555706, Length=259, Percent_Identity=25.8687258687259, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17531453, Length=267, Percent_Identity=26.9662921348315, Blast_Score=64, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=259, Percent_Identity=22.7799227799228, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI21355319, Length=254, Percent_Identity=27.5590551181102, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI23397609, Length=261, Percent_Identity=30.6513409961686, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21357041, Length=256, Percent_Identity=30.078125, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24639444, Length=261, Percent_Identity=27.2030651340996, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24644339, Length=258, Percent_Identity=27.906976744186, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI28571526, Length=253, Percent_Identity=28.8537549407115, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24643142, Length=253, Percent_Identity=23.7154150197628, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 27062; Mature: 27062

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDMGIAGRTALVCAASKGLGRGCAEALAAEGVDLTIVARTAETLEATAAEIRKQSGVEVK
CCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHCCCEEE
TVACDITTPEGRAAALAACPQPDILVNNAGGPPPGDFRNFTHEDWIRALESNMLTPIELI
EEEEEEECCCCCEEEEEECCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHH
RATIDSMSARGYGRIVNITSSAVKAPIDVLGLSNGARSGLTGFVAGLARKVAPTGVTINN
HHHHHHHCCCCCCEEEEECHHHHHCCHHEEECCCCCCCHHHHHHHHHHHHHCCCCEEHHH
LLPGIFDTDRIAVTFAAQARSQNISVDQARQQRMKTIPAGRFGNRDEFGRACAFLCSVHA
HCCCCCCCCCEEEEEEEHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHC
GYITGQNWLIDGGAYPGTF
CEEECCCEEEECCCCCCCC
>Mature Secondary Structure
MDMGIAGRTALVCAASKGLGRGCAEALAAEGVDLTIVARTAETLEATAAEIRKQSGVEVK
CCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHCCCEEE
TVACDITTPEGRAAALAACPQPDILVNNAGGPPPGDFRNFTHEDWIRALESNMLTPIELI
EEEEEEECCCCCEEEEEECCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHH
RATIDSMSARGYGRIVNITSSAVKAPIDVLGLSNGARSGLTGFVAGLARKVAPTGVTINN
HHHHHHHCCCCCCEEEEECHHHHHCCHHEEECCCCCCCHHHHHHHHHHHHHCCCCEEHHH
LLPGIFDTDRIAVTFAAQARSQNISVDQARQQRMKTIPAGRFGNRDEFGRACAFLCSVHA
HCCCCCCCCCEEEEEEEHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHC
GYITGQNWLIDGGAYPGTF
CEEECCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]