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The map label for this gene is mdlA [H]

Identifier: 91782474

GI number: 91782474

Start: 1224270

End: 1225436

Strand: Direct

Name: mdlA [H]

Synonym: Bxe_A3357

Alternate gene names: 91782474

Gene position: 1224270-1225436 (Clockwise)

Preceding gene: 91782468

Following gene: 91782475

Centisome position: 25.01

GC content: 60.67

Gene sequence:

>1167_bases
ATGAGAATCGTTGAAATCCGCGAAAAGACCATTCCGATCAGCTCACCCATCCGCAATGCCTATATCGACTTCAGCAAGAT
GACGCTGAGTCTCGTGGCCGTGGTGACTGACGTGATCCGTGACGGCAAACCGGTGGTCGGATACGGCTTCAACTCCAACG
GTCGCTACGGGCAAGGCACGCTGATGCGCGAACGTTTCATTCCGCGCATTCTCGAAGCGGACCCGGCCAGTCTCGTCAAC
GACGCCGGCGACAACCTCGATCCGCACAAGATCTGGGCGACGATGTTCAGCAACGAGAAACCCGGCGGCCACGGCGAGCG
CTCGGTTGCCATCGGGACGATCGACATGGCCGTGTGGGACGCCGTGGCGAAGATCGAAGGCCTGCCGCTGTTCCAGTTGC
TGGCCGACCGTTATGGCAACGGCCAGCCTGATCGCAAGATCTTCGTCTACGCCGCGGGCGGTTACTACTATCCGGGCCAG
GACCACGGCAAGCTCAAGGACGAGATGCGCAGCTATATCGACCGGGGCTACACCGTCGTGAAGAAGAAGATCGGCGGTGC
GTCGCTGGATGAAGATCTGCGTCGCATCGATTCGATCCTGAGCGTGCTGGGCGACGGCCAGAAGCTGGCGGTCGACGCCA
ACGGCAGATTCGATCTCGACACCGCCATTCAATACGCGAAGGCGCTGTCGCAATACGACCTGTTCTGGTACGAGGAACCG
GGCGATCCGCTCGACTTCGAATTGCAAGCGACACTTCGCAACTATTACGACAAGCCGATGGCAACCGGCGAAGATCTGTT
CTCGATGCAGGACGCGCGCAACCTGATTCGCTACGGCGGCATGCGCCCCGACCGCGACTGGCTGCAGTTCGACTGCGCGT
TGAGCTACGGACTGGTCGAATACCTGCGCACGCTGGAGATGCTGCATCAGCACGGCTGGTCGCCGAGCCGCTGCATTCCG
CACGGCGGGCATCAGATGTCGTTGAACATTGCGGCTGGCCTCGGGCTCGGCGGCAACGAATCCTATCCGGACCTGTTCCA
GCCTTTTGGCGGCTTCCCGGATGGCGTGAAGGTCGAAAACGGACATATCACCATGCCCGATCTGCCCGGCATCGGCTTTG
AAGGAAAGGCCGATCTGTTTGCCGAGATGCAGCGGTTGTCCGCATGA

Upstream 100 bases:

>100_bases
GTGACCGTGAGTGAATCATAGCGCTACTTTTCGCGACTAACCTAGCGACTCCCACAGCCCGTTGCATTGGCAACGTGCGA
TGCCCCATCAGGAGACATCC

Downstream 100 bases:

>100_bases
GCCGTTCGCCGGCAACTGCGCCGACCGGAAGTGTCGGCGCGGCATTGACAGAATAAGAAGAGGAATGCCGGCGGATTCGA
TTCGGGCTCACGGTAGCGGC

Product: putative mandelate racemase

Products: NA

Alternate protein names: MR [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MRIVEIREKTIPISSPIRNAYIDFSKMTLSLVAVVTDVIRDGKPVVGYGFNSNGRYGQGTLMRERFIPRILEADPASLVN
DAGDNLDPHKIWATMFSNEKPGGHGERSVAIGTIDMAVWDAVAKIEGLPLFQLLADRYGNGQPDRKIFVYAAGGYYYPGQ
DHGKLKDEMRSYIDRGYTVVKKKIGGASLDEDLRRIDSILSVLGDGQKLAVDANGRFDLDTAIQYAKALSQYDLFWYEEP
GDPLDFELQATLRNYYDKPMATGEDLFSMQDARNLIRYGGMRPDRDWLQFDCALSYGLVEYLRTLEMLHQHGWSPSRCIP
HGGHQMSLNIAAGLGLGGNESYPDLFQPFGGFPDGVKVENGHITMPDLPGIGFEGKADLFAEMQRLSA

Sequences:

>Translated_388_residues
MRIVEIREKTIPISSPIRNAYIDFSKMTLSLVAVVTDVIRDGKPVVGYGFNSNGRYGQGTLMRERFIPRILEADPASLVN
DAGDNLDPHKIWATMFSNEKPGGHGERSVAIGTIDMAVWDAVAKIEGLPLFQLLADRYGNGQPDRKIFVYAAGGYYYPGQ
DHGKLKDEMRSYIDRGYTVVKKKIGGASLDEDLRRIDSILSVLGDGQKLAVDANGRFDLDTAIQYAKALSQYDLFWYEEP
GDPLDFELQATLRNYYDKPMATGEDLFSMQDARNLIRYGGMRPDRDWLQFDCALSYGLVEYLRTLEMLHQHGWSPSRCIP
HGGHQMSLNIAAGLGLGGNESYPDLFQPFGGFPDGVKVENGHITMPDLPGIGFEGKADLFAEMQRLSA
>Mature_388_residues
MRIVEIREKTIPISSPIRNAYIDFSKMTLSLVAVVTDVIRDGKPVVGYGFNSNGRYGQGTLMRERFIPRILEADPASLVN
DAGDNLDPHKIWATMFSNEKPGGHGERSVAIGTIDMAVWDAVAKIEGLPLFQLLADRYGNGQPDRKIFVYAAGGYYYPGQ
DHGKLKDEMRSYIDRGYTVVKKKIGGASLDEDLRRIDSILSVLGDGQKLAVDANGRFDLDTAIQYAKALSQYDLFWYEEP
GDPLDFELQATLRNYYDKPMATGEDLFSMQDARNLIRYGGMRPDRDWLQFDCALSYGLVEYLRTLEMLHQHGWSPSRCIP
HGGHQMSLNIAAGLGLGGNESYPDLFQPFGGFPDGVKVENGHITMPDLPGIGFEGKADLFAEMQRLSA

Specific function: Probably Involved In The Degradation Of Homoserine Lactone (Hsl) Or Of A Metabolite Of Hsl That Signals Starvation. [C]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018110
- InterPro:   IPR015654
- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =5.1.2.2 [H]

Molecular weight: Translated: 43209; Mature: 43209

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIVEIREKTIPISSPIRNAYIDFSKMTLSLVAVVTDVIRDGKPVVGYGFNSNGRYGQGT
CCEEEEHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCH
LMRERFIPRILEADPASLVNDAGDNLDPHKIWATMFSNEKPGGHGERSVAIGTIDMAVWD
HHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEHHHHHHH
AVAKIEGLPLFQLLADRYGNGQPDRKIFVYAAGGYYYPGQDHGKLKDEMRSYIDRGYTVV
HHHHHCCCHHHHHHHHHCCCCCCCCEEEEEECCCEECCCCCCCHHHHHHHHHHHCCHHHH
KKKIGGASLDEDLRRIDSILSVLGDGQKLAVDANGRFDLDTAIQYAKALSQYDLFWYEEP
HHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCEEEEECC
GDPLDFELQATLRNYYDKPMATGEDLFSMQDARNLIRYGGMRPDRDWLQFDCALSYGLVE
CCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
YLRTLEMLHQHGWSPSRCIPHGGHQMSLNIAAGLGLGGNESYPDLFQPFGGFPDGVKVEN
HHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCHHHHHCCCCCCCEEECC
GHITMPDLPGIGFEGKADLFAEMQRLSA
CEEECCCCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MRIVEIREKTIPISSPIRNAYIDFSKMTLSLVAVVTDVIRDGKPVVGYGFNSNGRYGQGT
CCEEEEHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCH
LMRERFIPRILEADPASLVNDAGDNLDPHKIWATMFSNEKPGGHGERSVAIGTIDMAVWD
HHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEHHHHHHH
AVAKIEGLPLFQLLADRYGNGQPDRKIFVYAAGGYYYPGQDHGKLKDEMRSYIDRGYTVV
HHHHHCCCHHHHHHHHHCCCCCCCCEEEEEECCCEECCCCCCCHHHHHHHHHHHCCHHHH
KKKIGGASLDEDLRRIDSILSVLGDGQKLAVDANGRFDLDTAIQYAKALSQYDLFWYEEP
HHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCEEEEECC
GDPLDFELQATLRNYYDKPMATGEDLFSMQDARNLIRYGGMRPDRDWLQFDCALSYGLVE
CCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
YLRTLEMLHQHGWSPSRCIPHGGHQMSLNIAAGLGLGGNESYPDLFQPFGGFPDGVKVEN
HHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCHHHHHCCCCCCCEEECC
GHITMPDLPGIGFEGKADLFAEMQRLSA
CEEECCCCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2831968; 2271624; 2215699; 1909893; 1892834; 7893689; 7893690 [H]