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The map label for this gene is lldD [H]

Identifier: 91782463

GI number: 91782463

Start: 1210057

End: 1211277

Strand: Direct

Name: lldD [H]

Synonym: Bxe_A3368

Alternate gene names: 91782463

Gene position: 1210057-1211277 (Clockwise)

Preceding gene: 91782462

Following gene: 91782464

Centisome position: 24.72

GC content: 69.29

Gene sequence:

>1221_bases
ATGGCCGATACGATTACCTGTGTCGACGATCTGCAGCGGCTCGCGCGCCGGCGCGTGCCGAAGATTTTCTACGACTACGT
GGACAGCGGCTCGTGGACCGAGTCCACCTATCGGGCGAACGAAACGGACCTCGGCAGCCTGAGGTTCCGCCAGCGCGTGG
GCTGCAACGTCGAGGCGATCCGCACCGCGTCGACGCTGCTCGGCCACGCGTGCAGCCTGCCGCTCGCGCTTGCGCCGACC
GGCCTCGCAGGCATGGTGCACGCGGACGGCGAGATCCTCGCCGCGCGGGCGGCCGCAAGGTTCGGCGTACCGTTCACGCT
GTCCACGGTCAGCATCTGCTCGATCGAGGACGTGGCCGAGCAGGTCGCGCAGCCGTTCTGGTTCCAGCTGTACATGATGA
AGGACCGCGATTTCATCGTCCGGCTGATCGAGCGCGCGCGCGACGCGGGCTGCTCCGCGCTCGTGCTGACGCTCGATCTG
CCGATCCAGGGGCAGCGCCACAAGGACGTGCGCAACGGCCTGTCGGTGCCGCCGAAACTGAACGTGCGAAATCTGTCCAC
CATGCTGTCGCGGCCCGCATGGTGCGCGCGCATGCTGGGCACGCGGCGGCGCACGTTCGGCAATATCGTCGGGCATGCGA
AGGGCGTATCGGACACGTTCGCGTTCGCGGAATGGGTGAGCCGGCAGTTCGACCGCAGCGTGACGTGGGACGACGTCCGC
TGGATCAAGCGCCATTGGGGCGGCCGGCTGATCGTGAAGGGCATTCTCGACGCCGACGACGCGCGCCTCGCGGTCGCGGC
CGGCGCCGATGCGATCGTCGTGTCGAACCACGGCGGCCGGCAACTGGACGGCGCGCCCTCGTCGATCAGCGCGTTGCCGG
CGATCGCCGCGGCGGTCGGCAGGCAGACCGAAGTACTGATGGACGGCGGCATCCGCAGCGGCCAGGACGTGCTGCGCGCA
CTCGCATGGGGCGCGCACGGCGTGATGATCGGCCGTGCGTTTCTATACGGCCTCGGCGCGCTCGGTGAGGCGGGCGTCAC
GCGCACGCTCGAACTCATCCAGAAGGAACTCGAATCGACGATGGCGCTGTGCGGCATCACCGACGTCGCCGACGTCGGCC
GCGACGCGATCGTCTCGCCGGCGCACGGCGCCGCGCCCGCGTGGCCCGAACCGGTCGGCCGGCGCGTTGGTGAAAGCAAT
CTTCCGGTGCTTGCTTCGTGA

Upstream 100 bases:

>100_bases
GTCTACCTGCAGGCCGGCCAGACCGTGCGTGCCGGGATCGCGGGCCTTGGCGAGCAGTCGTCGCCGGTGGTCGCGTTCCA
CGCGACAGCGCAGGCCTGAC

Downstream 100 bases:

>100_bases
GCACCCCTTCATTTTTTCAAGGAGACATTTGATGTTCGGTAACTACAAGATGCACGAAGGCAGCGGTGTGAACCCGCCTT
ACTCGCCCGCTTATCCCGTC

Product: L-lactate dehydrogenase (cytochrome)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MADTITCVDDLQRLARRRVPKIFYDYVDSGSWTESTYRANETDLGSLRFRQRVGCNVEAIRTASTLLGHACSLPLALAPT
GLAGMVHADGEILAARAAARFGVPFTLSTVSICSIEDVAEQVAQPFWFQLYMMKDRDFIVRLIERARDAGCSALVLTLDL
PIQGQRHKDVRNGLSVPPKLNVRNLSTMLSRPAWCARMLGTRRRTFGNIVGHAKGVSDTFAFAEWVSRQFDRSVTWDDVR
WIKRHWGGRLIVKGILDADDARLAVAAGADAIVVSNHGGRQLDGAPSSISALPAIAAAVGRQTEVLMDGGIRSGQDVLRA
LAWGAHGVMIGRAFLYGLGALGEAGVTRTLELIQKELESTMALCGITDVADVGRDAIVSPAHGAAPAWPEPVGRRVGESN
LPVLAS

Sequences:

>Translated_406_residues
MADTITCVDDLQRLARRRVPKIFYDYVDSGSWTESTYRANETDLGSLRFRQRVGCNVEAIRTASTLLGHACSLPLALAPT
GLAGMVHADGEILAARAAARFGVPFTLSTVSICSIEDVAEQVAQPFWFQLYMMKDRDFIVRLIERARDAGCSALVLTLDL
PIQGQRHKDVRNGLSVPPKLNVRNLSTMLSRPAWCARMLGTRRRTFGNIVGHAKGVSDTFAFAEWVSRQFDRSVTWDDVR
WIKRHWGGRLIVKGILDADDARLAVAAGADAIVVSNHGGRQLDGAPSSISALPAIAAAVGRQTEVLMDGGIRSGQDVLRA
LAWGAHGVMIGRAFLYGLGALGEAGVTRTLELIQKELESTMALCGITDVADVGRDAIVSPAHGAAPAWPEPVGRRVGESN
LPVLAS
>Mature_405_residues
ADTITCVDDLQRLARRRVPKIFYDYVDSGSWTESTYRANETDLGSLRFRQRVGCNVEAIRTASTLLGHACSLPLALAPTG
LAGMVHADGEILAARAAARFGVPFTLSTVSICSIEDVAEQVAQPFWFQLYMMKDRDFIVRLIERARDAGCSALVLTLDLP
IQGQRHKDVRNGLSVPPKLNVRNLSTMLSRPAWCARMLGTRRRTFGNIVGHAKGVSDTFAFAEWVSRQFDRSVTWDDVRW
IKRHWGGRLIVKGILDADDARLAVAAGADAIVVSNHGGRQLDGAPSSISALPAIAAAVGRQTEVLMDGGIRSGQDVLRAL
AWGAHGVMIGRAFLYGLGALGEAGVTRTLELIQKELESTMALCGITDVADVGRDAIVSPAHGAAPAWPEPVGRRVGESNL
PVLAS

Specific function: Unknown

COG id: COG1304

COG function: function code C; L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FMN hydroxy acid dehydrogenase domain [H]

Homologues:

Organism=Homo sapiens, GI11068137, Length=375, Percent_Identity=36, Blast_Score=251, Evalue=9e-67,
Organism=Homo sapiens, GI54234014, Length=378, Percent_Identity=35.978835978836, Blast_Score=220, Evalue=2e-57,
Organism=Homo sapiens, GI7705393, Length=378, Percent_Identity=35.978835978836, Blast_Score=220, Evalue=2e-57,
Organism=Escherichia coli, GI1790033, Length=394, Percent_Identity=43.6548223350254, Blast_Score=327, Evalue=6e-91,
Organism=Caenorhabditis elegans, GI193208036, Length=375, Percent_Identity=36.5333333333333, Blast_Score=234, Evalue=6e-62,
Organism=Caenorhabditis elegans, GI32566217, Length=289, Percent_Identity=34.6020761245675, Blast_Score=165, Evalue=4e-41,
Organism=Saccharomyces cerevisiae, GI6323587, Length=386, Percent_Identity=29.2746113989637, Blast_Score=174, Evalue=3e-44,
Organism=Drosophila melanogaster, GI281363140, Length=384, Percent_Identity=38.28125, Blast_Score=251, Evalue=5e-67,
Organism=Drosophila melanogaster, GI78707190, Length=384, Percent_Identity=38.28125, Blast_Score=251, Evalue=5e-67,
Organism=Drosophila melanogaster, GI78707188, Length=381, Percent_Identity=38.3202099737533, Blast_Score=251, Evalue=6e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR012133
- InterPro:   IPR000262
- InterPro:   IPR008259
- InterPro:   IPR020920 [H]

Pfam domain/function: PF01070 FMN_dh [H]

EC number: =1.1.2.3 [H]

Molecular weight: Translated: 43822; Mature: 43691

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: PS00557 FMN_HYDROXY_ACID_DH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADTITCVDDLQRLARRRVPKIFYDYVDSGSWTESTYRANETDLGSLRFRQRVGCNVEAI
CCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHCCCCCCCCHHHHHHHHHCCCHHHH
RTASTLLGHACSLPLALAPTGLAGMVHADGEILAARAAARFGVPFTLSTVSICSIEDVAE
HHHHHHHHHHHCCCCEECCCCCCEEEECCCHHHHHHHHHHCCCCEEECCEEHHHHHHHHH
QVAQPFWFQLYMMKDRDFIVRLIERARDAGCSALVLTLDLPIQGQRHKDVRNGLSVPPKL
HHCCCCEEEEEEECCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHCCCCCCCCC
NVRNLSTMLSRPAWCARMLGTRRRTFGNIVGHAKGVSDTFAFAEWVSRQFDRSVTWDDVR
CHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHH
WIKRHWGGRLIVKGILDADDARLAVAAGADAIVVSNHGGRQLDGAPSSISALPAIAAAVG
HHHHHCCCEEEEEEECCCCCCEEEEECCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHC
RQTEVLMDGGIRSGQDVLRALAWGAHGVMIGRAFLYGLGALGEAGVTRTLELIQKELEST
CCCEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
MALCGITDVADVGRDAIVSPAHGAAPAWPEPVGRRVGESNLPVLAS
HHHHCCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCEECC
>Mature Secondary Structure 
ADTITCVDDLQRLARRRVPKIFYDYVDSGSWTESTYRANETDLGSLRFRQRVGCNVEAI
CCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHCCCCCCCCHHHHHHHHHCCCHHHH
RTASTLLGHACSLPLALAPTGLAGMVHADGEILAARAAARFGVPFTLSTVSICSIEDVAE
HHHHHHHHHHHCCCCEECCCCCCEEEECCCHHHHHHHHHHCCCCEEECCEEHHHHHHHHH
QVAQPFWFQLYMMKDRDFIVRLIERARDAGCSALVLTLDLPIQGQRHKDVRNGLSVPPKL
HHCCCCEEEEEEECCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHCCCCCCCCC
NVRNLSTMLSRPAWCARMLGTRRRTFGNIVGHAKGVSDTFAFAEWVSRQFDRSVTWDDVR
CHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHH
WIKRHWGGRLIVKGILDADDARLAVAAGADAIVVSNHGGRQLDGAPSSISALPAIAAAVG
HHHHHCCCEEEEEEECCCCCCEEEEECCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHC
RQTEVLMDGGIRSGQDVLRALAWGAHGVMIGRAFLYGLGALGEAGVTRTLELIQKELEST
CCCEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
MALCGITDVADVGRDAIVSPAHGAAPAWPEPVGRRVGESNLPVLAS
HHHHCCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA