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The map label for this gene is argE [H]

Identifier: 91782368

GI number: 91782368

Start: 1104948

End: 1106114

Strand: Direct

Name: argE [H]

Synonym: Bxe_A3463

Alternate gene names: 91782368

Gene position: 1104948-1106114 (Clockwise)

Preceding gene: 91782367

Following gene: 91782370

Centisome position: 22.57

GC content: 63.84

Gene sequence:

>1167_bases
ATGAGTGACCGATCCAGCCAGGCGCTGCTGGAACAACTGATCGGCTTCGCCACGGTCAGCCGCGAGTCCAATCTGGACAT
GATCGGATTCATTCGGGATTACCTCGGGGAACTCGGAGTCGGGAGCGAGCTGTTCTACAACGCCGGGCGTACCAAGGCGA
ATCTGTTCGCGACCATCGGTCCGCGTGAGCGCGGCGGTATCGTGCTGTCCGGTCACACCGACGTGGTGCCGGTCGACGGC
CAGGCGTGGACCGTCGACGCCTTCCGCCTTACCGAACGCGACGGGCGGCTCTATGGCCGCGGCACGGCCGACATGAAGGG
CTTCATCGCTTCGGTGCTGGCGGCAGTGCCTGTGTTTCTTGAGCGCGAACTGAAGCTGCCGGTCCATCTCGCCTTTTCGT
ACGACGAGGAAGTGGGATGCCTCGGCGTGCGGCCCATGCTGGCGGAACTGGAGCGGCGCCCGCATAAGCCGGCTCTGTGC
CTGATCGGCGAGCCGACCGAACTCAAGCCGGTGCTGGGTCACAAGGGCAAGCTGGCGATGCGTTGTCACGTGAAAGGTGC
GGCTTGCCATTCGGCTTACGCGCCGTACGGCGTCAATGCCATTCAATACGCGGCGCGAATGATCGGCCATCTGGAAGAGA
TTGGCGAGCAACTGGCGCGGCCCGAGCATCACGACGAGCGATTCGATCCGCCGTTCTCCACCGTGCAGACGGGTGTGATC
AAAGGCGGCCACGCGCTCAACATCGTGCCCGCCGAATGTGAATTCGACTTCGAAGTGCGGGCGCTGCCCGGCTTTGACGC
CCACCAGGTAGCCGACGAGTTGCAGACCTACGCCGAAGCCGAATTGCTGCCGAAGATGCGCGCCGTGAAGTCCGACACCG
ACATCCGTTTTCAGTCGCTCTCCGCCTACCCGGGATTGGCTACTTCGCCCGATAGCGAAGCGGCGCGTCTCGTGGCGCTG
CTCAGCGGTTCCACCGAGTTCGGCACGGTTGCGTTCGGCACCGAGGGCGGCCTCTTCGATCAGGCTGGCATTCCCACGGT
GGTTTGCGGACCGGGCAGCATGGACCAGGGGCATAAGCCGGACGAGTTCGTCAGCGTCGAGCAATTGCGCCAGTGCGATG
CGATGCTGATTCGTCTGGCGGACCATCTGTCGGCCAATCTCGCCTGA

Upstream 100 bases:

>100_bases
CAGCTCGACCGTCTATGGCACGCATATCGGCCGCAGATGCAGGATTACGTGACCCGGGCGCTGAATCCGACTGCCGCGCC
CAGCTACGGAGTGCCAGGCG

Downstream 100 bases:

>100_bases
GGTTCCGCGCGGGACGGGCGGGACATCTGAACCGAAAGATGCGTTACGACGCTGCCTGCCCGCGGAGCATGGACGCTCCC
GGCGCACAGAGGTCCGATCA

Product: acetylornithine deacetylase

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO [H]

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MSDRSSQALLEQLIGFATVSRESNLDMIGFIRDYLGELGVGSELFYNAGRTKANLFATIGPRERGGIVLSGHTDVVPVDG
QAWTVDAFRLTERDGRLYGRGTADMKGFIASVLAAVPVFLERELKLPVHLAFSYDEEVGCLGVRPMLAELERRPHKPALC
LIGEPTELKPVLGHKGKLAMRCHVKGAACHSAYAPYGVNAIQYAARMIGHLEEIGEQLARPEHHDERFDPPFSTVQTGVI
KGGHALNIVPAECEFDFEVRALPGFDAHQVADELQTYAEAELLPKMRAVKSDTDIRFQSLSAYPGLATSPDSEAARLVAL
LSGSTEFGTVAFGTEGGLFDQAGIPTVVCGPGSMDQGHKPDEFVSVEQLRQCDAMLIRLADHLSANLA

Sequences:

>Translated_388_residues
MSDRSSQALLEQLIGFATVSRESNLDMIGFIRDYLGELGVGSELFYNAGRTKANLFATIGPRERGGIVLSGHTDVVPVDG
QAWTVDAFRLTERDGRLYGRGTADMKGFIASVLAAVPVFLERELKLPVHLAFSYDEEVGCLGVRPMLAELERRPHKPALC
LIGEPTELKPVLGHKGKLAMRCHVKGAACHSAYAPYGVNAIQYAARMIGHLEEIGEQLARPEHHDERFDPPFSTVQTGVI
KGGHALNIVPAECEFDFEVRALPGFDAHQVADELQTYAEAELLPKMRAVKSDTDIRFQSLSAYPGLATSPDSEAARLVAL
LSGSTEFGTVAFGTEGGLFDQAGIPTVVCGPGSMDQGHKPDEFVSVEQLRQCDAMLIRLADHLSANLA
>Mature_387_residues
SDRSSQALLEQLIGFATVSRESNLDMIGFIRDYLGELGVGSELFYNAGRTKANLFATIGPRERGGIVLSGHTDVVPVDGQ
AWTVDAFRLTERDGRLYGRGTADMKGFIASVLAAVPVFLERELKLPVHLAFSYDEEVGCLGVRPMLAELERRPHKPALCL
IGEPTELKPVLGHKGKLAMRCHVKGAACHSAYAPYGVNAIQYAARMIGHLEEIGEQLARPEHHDERFDPPFSTVQTGVIK
GGHALNIVPAECEFDFEVRALPGFDAHQVADELQTYAEAELLPKMRAVKSDTDIRFQSLSAYPGLATSPDSEAARLVALL
SGSTEFGTVAFGTEGGLFDQAGIPTVVCGPGSMDQGHKPDEFVSVEQLRQCDAMLIRLADHLSANLA

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=364, Percent_Identity=35.4395604395604, Blast_Score=198, Evalue=5e-52,
Organism=Escherichia coli, GI1788816, Length=217, Percent_Identity=31.3364055299539, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1789236, Length=335, Percent_Identity=24.1791044776119, Blast_Score=72, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17551016, Length=349, Percent_Identity=27.2206303724928, Blast_Score=89, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.16 [H]

Molecular weight: Translated: 42016; Mature: 41885

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS00759 ARGE_DAPE_CPG2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDRSSQALLEQLIGFATVSRESNLDMIGFIRDYLGELGVGSELFYNAGRTKANLFATIG
CCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCCCCEEEEEEEC
PRERGGIVLSGHTDVVPVDGQAWTVDAFRLTERDGRLYGRGTADMKGFIASVLAAVPVFL
CCCCCCEEEECCCCEEECCCCEEEEEEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHH
ERELKLPVHLAFSYDEEVGCLGVRPMLAELERRPHKPALCLIGEPTELKPVLGHKGKLAM
HHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCHHHCCCCCEEE
RCHVKGAACHSAYAPYGVNAIQYAARMIGHLEEIGEQLARPEHHDERFDPPFSTVQTGVI
EEEECCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHC
KGGHALNIVPAECEFDFEVRALPGFDAHQVADELQTYAEAELLPKMRAVKSDTDIRFQSL
CCCCEEEEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEC
SAYPGLATSPDSEAARLVALLSGSTEFGTVAFGTEGGLFDQAGIPTVVCGPGSMDQGHKP
CCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCEEEECCCCCCCCCCC
DEFVSVEQLRQCDAMLIRLADHLSANLA
HHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SDRSSQALLEQLIGFATVSRESNLDMIGFIRDYLGELGVGSELFYNAGRTKANLFATIG
CCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCCCCEEEEEEEC
PRERGGIVLSGHTDVVPVDGQAWTVDAFRLTERDGRLYGRGTADMKGFIASVLAAVPVFL
CCCCCCEEEECCCCEEECCCCEEEEEEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHH
ERELKLPVHLAFSYDEEVGCLGVRPMLAELERRPHKPALCLIGEPTELKPVLGHKGKLAM
HHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCHHHCCCCCEEE
RCHVKGAACHSAYAPYGVNAIQYAARMIGHLEEIGEQLARPEHHDERFDPPFSTVQTGVI
EEEECCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHC
KGGHALNIVPAECEFDFEVRALPGFDAHQVADELQTYAEAELLPKMRAVKSDTDIRFQSL
CCCCEEEEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEC
SAYPGLATSPDSEAARLVALLSGSTEFGTVAFGTEGGLFDQAGIPTVVCGPGSMDQGHKP
CCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCEEEECCCCCCCCCCC
DEFVSVEQLRQCDAMLIRLADHLSANLA
HHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9829957 [H]