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The map label for this gene is panC [H]

Identifier: 91782343

GI number: 91782343

Start: 1072739

End: 1073572

Strand: Reverse

Name: panC [H]

Synonym: Bxe_A3488

Alternate gene names: 91782343

Gene position: 1073572-1072739 (Counterclockwise)

Preceding gene: 91782344

Following gene: 91782342

Centisome position: 21.93

GC content: 64.39

Gene sequence:

>834_bases
ATGAAAGTCATCAGCTCGATCCATGAATTGCGCGACCAGTTGCGCGGCCAGAATCGCACCGCGTTTGTGCCGACTATGGG
CAATCTGCACGAGGGTCATCTGTCGCTGATGCGCCTCGCGCGCCAGCACGGCGACCCGGTGGTGGCCAGCATCTTCGTCA
ACCGGCTGCAGTTCGGTCCGAACGAGGACTTCGACAAATACCCGCGCACGATGGAAGCGGACATCGAGAAGCTGCAGAAG
GAAAACGTCTACGTACTGTTCGCGCCGACGGAAAAGGACCTCTATCCGGAGCCGCAGGAGTACCGCGTGCATCCGCCGCA
CGATCTGGGCGATATCCTCGAAGGCGAATTCCGGCCGGGCTTCTTCCAGGGCGTGTGCACGGTGGTGATGAAGCTGATGT
CGTGCGTGCAGCCGCGCGTCGCCGTGTTCGGCAAGAAGGACTACCAGCAGTTGATGATCGTGCGCCGCATGTGCAACCAG
TTCGCGCTGCCCACCGACATCATCGCCGCCGAAACCGTGCGCGATGCCGACGGCCTCGCGCTCAGCTCGCGCAATCGCTA
TCTGCAGGCCGCCGAGCGCGCCGAGGCGCCGAGGCTGGCCGCCGAACTGAATCAGGTGCGCGAAGCGGTGCTTGGCGGCG
AACGCGACTTCGCAAAAATCGAGCGGGCGGCAATGGCGGCTCTCGCCGCGCGCGGCTGGCAACCCGACTATATCGCCGTG
CGCAAGCGCTCGAATCTGCTGCCGCCGGGTCCGGAAGACGCGAATGCGGAACTGGTGGTGCTGGCCGCCGCCAGGCTCGG
CGCCACCCGTCTGATCGACAACCTCGAAATCTGA

Upstream 100 bases:

>100_bases
CTCCGAACCTGTCATTACCAGTGAGGCGGCGGCCCGCGCGATTCCTTAGGGTTTTGCGTCCACCCAGTCTCGCGCCGCGC
GAGGAAATCCCTGTCCGATC

Downstream 100 bases:

>100_bases
AACCGTCTTGCACGGGCGTCGACACGCATTAGAAATCACACAGGATTGGTCATGCAACGCAACATGCTGAAGTCGAAGAT
CCACCGCGTCGCGGTCACGC

Product: pantoate--beta-alanine ligase

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme [H]

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MKVISSIHELRDQLRGQNRTAFVPTMGNLHEGHLSLMRLARQHGDPVVASIFVNRLQFGPNEDFDKYPRTMEADIEKLQK
ENVYVLFAPTEKDLYPEPQEYRVHPPHDLGDILEGEFRPGFFQGVCTVVMKLMSCVQPRVAVFGKKDYQQLMIVRRMCNQ
FALPTDIIAAETVRDADGLALSSRNRYLQAAERAEAPRLAAELNQVREAVLGGERDFAKIERAAMAALAARGWQPDYIAV
RKRSNLLPPGPEDANAELVVLAAARLGATRLIDNLEI

Sequences:

>Translated_277_residues
MKVISSIHELRDQLRGQNRTAFVPTMGNLHEGHLSLMRLARQHGDPVVASIFVNRLQFGPNEDFDKYPRTMEADIEKLQK
ENVYVLFAPTEKDLYPEPQEYRVHPPHDLGDILEGEFRPGFFQGVCTVVMKLMSCVQPRVAVFGKKDYQQLMIVRRMCNQ
FALPTDIIAAETVRDADGLALSSRNRYLQAAERAEAPRLAAELNQVREAVLGGERDFAKIERAAMAALAARGWQPDYIAV
RKRSNLLPPGPEDANAELVVLAAARLGATRLIDNLEI
>Mature_277_residues
MKVISSIHELRDQLRGQNRTAFVPTMGNLHEGHLSLMRLARQHGDPVVASIFVNRLQFGPNEDFDKYPRTMEADIEKLQK
ENVYVLFAPTEKDLYPEPQEYRVHPPHDLGDILEGEFRPGFFQGVCTVVMKLMSCVQPRVAVFGKKDYQQLMIVRRMCNQ
FALPTDIIAAETVRDADGLALSSRNRYLQAAERAEAPRLAAELNQVREAVLGGERDFAKIERAAMAALAARGWQPDYIAV
RKRSNLLPPGPEDANAELVVLAAARLGATRLIDNLEI

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate [H]

COG id: COG0414

COG function: function code H; Panthothenate synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pantothenate synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786325, Length=279, Percent_Identity=43.010752688172, Blast_Score=211, Evalue=3e-56,
Organism=Saccharomyces cerevisiae, GI6322046, Length=301, Percent_Identity=35.2159468438538, Blast_Score=148, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR003721
- InterPro:   IPR014729 [H]

Pfam domain/function: PF02569 Pantoate_ligase [H]

EC number: =6.3.2.1 [H]

Molecular weight: Translated: 31132; Mature: 31132

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVISSIHELRDQLRGQNRTAFVPTMGNLHEGHLSLMRLARQHGDPVVASIFVNRLQFGP
CHHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
NEDFDKYPRTMEADIEKLQKENVYVLFAPTEKDLYPEPQEYRVHPPHDLGDILEGEFRPG
CCCHHHCCCHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCH
FFQGVCTVVMKLMSCVQPRVAVFGKKDYQQLMIVRRMCNQFALPTDIIAAETVRDADGLA
HHHHHHHHHHHHHHHHCHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCE
LSSRNRYLQAAERAEAPRLAAELNQVREAVLGGERDFAKIERAAMAALAARGWQPDYIAV
ECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHEE
RKRSNLLPPGPEDANAELVVLAAARLGATRLIDNLEI
ECCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKVISSIHELRDQLRGQNRTAFVPTMGNLHEGHLSLMRLARQHGDPVVASIFVNRLQFGP
CHHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
NEDFDKYPRTMEADIEKLQKENVYVLFAPTEKDLYPEPQEYRVHPPHDLGDILEGEFRPG
CCCHHHCCCHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCH
FFQGVCTVVMKLMSCVQPRVAVFGKKDYQQLMIVRRMCNQFALPTDIIAAETVRDADGLA
HHHHHHHHHHHHHHHHCHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCE
LSSRNRYLQAAERAEAPRLAAELNQVREAVLGGERDFAKIERAAMAALAARGWQPDYIAV
ECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHEE
RKRSNLLPPGPEDANAELVVLAAARLGATRLIDNLEI
ECCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA