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The map label for this gene is cobC [H]

Identifier: 91782336

GI number: 91782336

Start: 1066433

End: 1067503

Strand: Reverse

Name: cobC [H]

Synonym: Bxe_A3495

Alternate gene names: 91782336

Gene position: 1067503-1066433 (Counterclockwise)

Preceding gene: 91782337

Following gene: 91782335

Centisome position: 21.8

GC content: 67.97

Gene sequence:

>1071_bases
ATGAAAGGCCGCGTGAGCGAAGCGAACCAGGTGAAAAACGAACCCGGCGGCGCCGTGCGTGCCGTCGCCCACGGCGGCAA
TCTGCACGAAGCGGCCCGACGCTACGGCATTCCCTACGCGGACTGGCTCGATCTGTCGACGGGCATCAATCCGCACGGCT
ATCCGGTCCCACCGGTTCCAGCGGAACTCTGGCGCCGCCTGCCCGACGATGGCGACGATTTCGCCGCCTGCGCCGCGCGC
TACTACGGCGCGCCCGACGCCGCGCACGTGCTGCCGGTCGCAGGCAGCCAGGCGGCGATTCGCGCGCTGCCCGCATTGCT
GCCGCGCGCACGGGTCGGCATTGCGCCGCTCACGTACGGCGAATACGCGCCCGCGTTCGAACGCAACGGCCATGAAGCGA
CCCTGCTCGATATCTCGCGCGACACGCTGCCCGACACGCTCACCCATGCAGTCGTCGTGAATCCGAACAATCCGACCGCC
GAGCATCTGAGCACCGCGAAGCTGTTGCACTGGCATGCGCAGTTGAGCGCGCGCGGCGGCACGCTACTGGTCGATGAAGC
CTTCGCCGATACGATGCCCTCGGCCTCGCTCGCGGCGAACACCCATCGCGAAGGCTTGCTCGTACTGCGCTCGCCGGGAA
AGTTCTTCGGCCTCGCCGGCGTGCGCGCGGGCTTCGTGCTCGGCGCGCCTGCGCTGCTCGAACGTTTGCGCCACACGCTC
GGCGCGTGGACCGTCAGCGGGCCGGCACGTCACGCTGTCAAAGCCGCATTCGCCGATGTGGACTGGCAACGGCAGATGCG
CTCGCGCCTCGAAGCCGACAGCGCGCGGCTGGTCGAGTTGTTGCAGGCGCAACGTTTCGACATGCGCAGCACACCGCTCT
TCGCGTGGACTTGCGACGCCCGCGCCGCCGCTTTGCATGAAGCTTTAGCGCGGCGCGGCGTATGGACACGTCTGTTCACG
CCGTCGGCAAGCGTCAGATTCGGCTTGCCCGCGAACGAGGCCGAATGGACACGCTTCAGCGAGCGCTTGCACGAGGCCGT
TCGAGAGATCGACTCCATGCGAGCGGGTTGA

Upstream 100 bases:

>100_bases
GTGAACGCCGCGTTGTTGCTGGTCGAGCGCACGGTCGTTCTGTGGCTCGCCGTGCTGATCGTGCTGGCGCTGCTGAGCGT
GCCGTTTCATGTGTGACGGG

Downstream 100 bases:

>100_bases
TGCAGCAAAGAACTCGCGTTATTGCCACGCTCACGCCACGTCCGCCGCCTCTGCGCCAATGATCCGACTCGCCCGCTTCG
CCCTCGCCGCCGCGCTCCTC

Product: putative threonine-phosphate decarboxylase

Products: NA

Alternate protein names: L-threonine-O-3-phosphate decarboxylase [H]

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MKGRVSEANQVKNEPGGAVRAVAHGGNLHEAARRYGIPYADWLDLSTGINPHGYPVPPVPAELWRRLPDDGDDFAACAAR
YYGAPDAAHVLPVAGSQAAIRALPALLPRARVGIAPLTYGEYAPAFERNGHEATLLDISRDTLPDTLTHAVVVNPNNPTA
EHLSTAKLLHWHAQLSARGGTLLVDEAFADTMPSASLAANTHREGLLVLRSPGKFFGLAGVRAGFVLGAPALLERLRHTL
GAWTVSGPARHAVKAAFADVDWQRQMRSRLEADSARLVELLQAQRFDMRSTPLFAWTCDARAAALHEALARRGVWTRLFT
PSASVRFGLPANEAEWTRFSERLHEAVREIDSMRAG

Sequences:

>Translated_356_residues
MKGRVSEANQVKNEPGGAVRAVAHGGNLHEAARRYGIPYADWLDLSTGINPHGYPVPPVPAELWRRLPDDGDDFAACAAR
YYGAPDAAHVLPVAGSQAAIRALPALLPRARVGIAPLTYGEYAPAFERNGHEATLLDISRDTLPDTLTHAVVVNPNNPTA
EHLSTAKLLHWHAQLSARGGTLLVDEAFADTMPSASLAANTHREGLLVLRSPGKFFGLAGVRAGFVLGAPALLERLRHTL
GAWTVSGPARHAVKAAFADVDWQRQMRSRLEADSARLVELLQAQRFDMRSTPLFAWTCDARAAALHEALARRGVWTRLFT
PSASVRFGLPANEAEWTRFSERLHEAVREIDSMRAG
>Mature_356_residues
MKGRVSEANQVKNEPGGAVRAVAHGGNLHEAARRYGIPYADWLDLSTGINPHGYPVPPVPAELWRRLPDDGDDFAACAAR
YYGAPDAAHVLPVAGSQAAIRALPALLPRARVGIAPLTYGEYAPAFERNGHEATLLDISRDTLPDTLTHAVVVNPNNPTA
EHLSTAKLLHWHAQLSARGGTLLVDEAFADTMPSASLAANTHREGLLVLRSPGKFFGLAGVRAGFVLGAPALLERLRHTL
GAWTVSGPARHAVKAAFADVDWQRQMRSRLEADSARLVELLQAQRFDMRSTPLFAWTCDARAAALHEALARRGVWTRLFT
PSASVRFGLPANEAEWTRFSERLHEAVREIDSMRAG

Specific function: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1- amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin [H]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR005860
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =4.1.1.81 [H]

Molecular weight: Translated: 38634; Mature: 38634

Theoretical pI: Translated: 8.70; Mature: 8.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGRVSEANQVKNEPGGAVRAVAHGGNLHEAARRYGIPYADWLDLSTGINPHGYPVPPVP
CCCCCCCHHHHCCCCCCEEEEEECCCCHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCC
AELWRRLPDDGDDFAACAARYYGAPDAAHVLPVAGSQAAIRALPALLPRARVGIAPLTYG
HHHHHHCCCCCCHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCC
EYAPAFERNGHEATLLDISRDTLPDTLTHAVVVNPNNPTAEHLSTAKLLHWHAQLSARGG
CCCCHHHCCCCEEEEEECCHHCCCHHHCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCC
TLLVDEAFADTMPSASLAANTHREGLLVLRSPGKFFGLAGVRAGFVLGAPALLERLRHTL
EEEEEHHHHHCCCCCHHHHCCCCCCEEEEECCCCEEEHHHHHHHHHCCCHHHHHHHHHHH
GAWTVSGPARHAVKAAFADVDWQRQMRSRLEADSARLVELLQAQRFDMRSTPLFAWTCDA
CCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEECCH
RAAALHEALARRGVWTRLFTPSASVRFGLPANEAEWTRFSERLHEAVREIDSMRAG
HHHHHHHHHHHCCCEEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKGRVSEANQVKNEPGGAVRAVAHGGNLHEAARRYGIPYADWLDLSTGINPHGYPVPPVP
CCCCCCCHHHHCCCCCCEEEEEECCCCHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCC
AELWRRLPDDGDDFAACAARYYGAPDAAHVLPVAGSQAAIRALPALLPRARVGIAPLTYG
HHHHHHCCCCCCHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCC
EYAPAFERNGHEATLLDISRDTLPDTLTHAVVVNPNNPTAEHLSTAKLLHWHAQLSARGG
CCCCHHHCCCCEEEEEECCHHCCCHHHCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCC
TLLVDEAFADTMPSASLAANTHREGLLVLRSPGKFFGLAGVRAGFVLGAPALLERLRHTL
EEEEEHHHHHCCCCCHHHHCCCCCCEEEEECCCCEEEHHHHHHHHHCCCHHHHHHHHHHH
GAWTVSGPARHAVKAAFADVDWQRQMRSRLEADSARLVELLQAQRFDMRSTPLFAWTCDA
CCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEECCH
RAAALHEALARRGVWTRLFTPSASVRFGLPANEAEWTRFSERLHEAVREIDSMRAG
HHHHHHHHHHHCCCEEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]