| Definition | Burkholderia xenovorans LB400 chromosome 1, complete sequence. |
|---|---|
| Accession | NC_007951 |
| Length | 4,895,836 |
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The map label for this gene is cmtB [H]
Identifier: 91782281
GI number: 91782281
Start: 1009272
End: 1010042
Strand: Direct
Name: cmtB [H]
Synonym: Bxe_A3553
Alternate gene names: 91782281
Gene position: 1009272-1010042 (Clockwise)
Preceding gene: 91782280
Following gene: 91782282
Centisome position: 20.61
GC content: 61.35
Gene sequence:
>771_bases ATGAAGAAAAAACAGACCAGTCTGGAAGGGCAGGTTGCGGTGGTCAGTGGTGGCGCTCATGGCATCGGACTGGGCATTGT CGAGCGGCTGCTGCAACTTGGCGCGAAGGTCGTGGCATCGGACATCGACAGGGACGGTCTTGCGGTGTCTCGCGAGCGTC TCGCGAAGTCGTTCGGCACTTCGATCGCAGTGCAGGCAGCTGACCTGTCGAAGGAGCGCGGTGCACAGGCCCTGCATCGT GCGGTGGCCAAACGGTTTGGGCCGGCGCAGATCCTCGTGAACTGCGCAGGTGGTGGTGTGATCCGTCCTTTTCTCGAGCA CACGCCCGAGACGCTCAAGGCGACGATAGACAGGAATCTGTGGACGGTGATCTGGTGCAGCCGCGTATTTCTGCCTGACA TGATCGGCGCGAAGTACGGCCGGATCGTGAACATTGGTGCCGATTCGGTCCGCAACGGCTTGCCCGCACATGCGGGGTAC AACGCGGCCAAAGGCGGGATGCATGGGCTCACGACAGGCCTTGCGCGCGAGTTTGCGCTGAATGGCATTACGGTCAACAC CGTGGCGCCATGCGCGGTGAACACCGAAGTCTGGGCGAAGGTGAAGAAGTCGAATCCCAGGCTCGCCCAGGCGTTCGTGG ACGTTATTCCGATGGGGCGCGTGGGTGAAATAGAGGAGGTCGCTTCAATGGTGGGTTACCTGGCATTGCCGGAGGCGGCC TTTGTCACCGGCCAGGTGATCAGCGTCAATGGTGGCAGTGCGATGTTGTGA
Upstream 100 bases:
>100_bases GCGCGGTGCCGGACGGACAGTTCGGCCGCAGTGGTCCGATTGAACGGGAAGCGGTCGAAGTTTCCACTCAAAAAATCCAG AAGGTGGTTGGTTAAGCGAA
Downstream 100 bases:
>100_bases GGATGAGGATGAGTACAACCACTGAAATGGTCGATCTGTGTGCAACCGGCGAGGTTGGTGACGGCGATATCCGCCGTGGT GCGCTGCCGTCGGGGCACGC
Product: 2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase(CmtB)
Products: NA
Alternate protein names: Biphenyl-2,3-dihydro-2,3-diol dehydrogenase [H]
Number of amino acids: Translated: 256; Mature: 256
Protein sequence:
>256_residues MKKKQTSLEGQVAVVSGGAHGIGLGIVERLLQLGAKVVASDIDRDGLAVSRERLAKSFGTSIAVQAADLSKERGAQALHR AVAKRFGPAQILVNCAGGGVIRPFLEHTPETLKATIDRNLWTVIWCSRVFLPDMIGAKYGRIVNIGADSVRNGLPAHAGY NAAKGGMHGLTTGLAREFALNGITVNTVAPCAVNTEVWAKVKKSNPRLAQAFVDVIPMGRVGEIEEVASMVGYLALPEAA FVTGQVISVNGGSAML
Sequences:
>Translated_256_residues MKKKQTSLEGQVAVVSGGAHGIGLGIVERLLQLGAKVVASDIDRDGLAVSRERLAKSFGTSIAVQAADLSKERGAQALHR AVAKRFGPAQILVNCAGGGVIRPFLEHTPETLKATIDRNLWTVIWCSRVFLPDMIGAKYGRIVNIGADSVRNGLPAHAGY NAAKGGMHGLTTGLAREFALNGITVNTVAPCAVNTEVWAKVKKSNPRLAQAFVDVIPMGRVGEIEEVASMVGYLALPEAA FVTGQVISVNGGSAML >Mature_256_residues MKKKQTSLEGQVAVVSGGAHGIGLGIVERLLQLGAKVVASDIDRDGLAVSRERLAKSFGTSIAVQAADLSKERGAQALHR AVAKRFGPAQILVNCAGGGVIRPFLEHTPETLKATIDRNLWTVIWCSRVFLPDMIGAKYGRIVNIGADSVRNGLPAHAGY NAAKGGMHGLTTGLAREFALNGITVNTVAPCAVNTEVWAKVKKSNPRLAQAFVDVIPMGRVGEIEEVASMVGYLALPEAA FVTGQVISVNGGSAML
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI19923817, Length=257, Percent_Identity=31.5175097276265, Blast_Score=112, Evalue=3e-25, Organism=Homo sapiens, GI4758504, Length=262, Percent_Identity=30.5343511450382, Blast_Score=99, Evalue=5e-21, Organism=Homo sapiens, GI7705925, Length=249, Percent_Identity=31.3253012048193, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI15277342, Length=262, Percent_Identity=30.5343511450382, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI40254992, Length=259, Percent_Identity=30.1158301158301, Blast_Score=93, Evalue=2e-19, Organism=Homo sapiens, GI83715985, Length=264, Percent_Identity=29.5454545454545, Blast_Score=85, Evalue=7e-17, Organism=Homo sapiens, GI32483357, Length=258, Percent_Identity=27.1317829457364, Blast_Score=85, Evalue=7e-17, Organism=Homo sapiens, GI10190704, Length=249, Percent_Identity=30.1204819277108, Blast_Score=84, Evalue=9e-17, Organism=Homo sapiens, GI5031737, Length=252, Percent_Identity=29.3650793650794, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI66933014, Length=227, Percent_Identity=29.0748898678414, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI40807363, Length=244, Percent_Identity=22.5409836065574, Blast_Score=75, Evalue=4e-14, Organism=Homo sapiens, GI142976729, Length=196, Percent_Identity=25, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI4503301, Length=256, Percent_Identity=25.390625, Blast_Score=68, Evalue=9e-12, Organism=Homo sapiens, GI126723750, Length=258, Percent_Identity=24.4186046511628, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI210032110, Length=196, Percent_Identity=25.5102040816327, Blast_Score=66, Evalue=3e-11, Organism=Escherichia coli, GI1787335, Length=253, Percent_Identity=33.201581027668, Blast_Score=119, Evalue=3e-28, Organism=Escherichia coli, GI1789057, Length=257, Percent_Identity=30.7392996108949, Blast_Score=99, Evalue=3e-22, Organism=Escherichia coli, GI87082100, Length=259, Percent_Identity=30.1158301158301, Blast_Score=98, Evalue=5e-22, Organism=Escherichia coli, GI87082160, Length=246, Percent_Identity=28.8617886178862, Blast_Score=94, Evalue=1e-20, Organism=Escherichia coli, GI2367175, Length=246, Percent_Identity=32.520325203252, Blast_Score=88, Evalue=5e-19, Organism=Escherichia coli, GI1787905, Length=245, Percent_Identity=27.7551020408163, Blast_Score=88, Evalue=6e-19, Organism=Escherichia coli, GI1789208, Length=248, Percent_Identity=31.8548387096774, Blast_Score=87, Evalue=1e-18, Organism=Escherichia coli, GI1790717, Length=246, Percent_Identity=26.8292682926829, Blast_Score=85, Evalue=4e-18, Organism=Escherichia coli, GI2367365, Length=250, Percent_Identity=32, Blast_Score=85, Evalue=6e-18, Organism=Escherichia coli, GI1788459, Length=245, Percent_Identity=30.6122448979592, Blast_Score=83, Evalue=1e-17, Organism=Escherichia coli, GI1789378, Length=250, Percent_Identity=27.6, Blast_Score=77, Evalue=8e-16, Organism=Escherichia coli, GI1787820, Length=171, Percent_Identity=25.1461988304094, Blast_Score=62, Evalue=5e-11, Organism=Caenorhabditis elegans, GI25147288, Length=250, Percent_Identity=33.6, Blast_Score=104, Evalue=5e-23, Organism=Caenorhabditis elegans, GI17555706, Length=253, Percent_Identity=27.6679841897233, Blast_Score=94, Evalue=6e-20, Organism=Caenorhabditis elegans, GI17561402, Length=251, Percent_Identity=28.6852589641434, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17562910, Length=262, Percent_Identity=28.6259541984733, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI71994604, Length=257, Percent_Identity=28.4046692607004, Blast_Score=81, Evalue=7e-16, Organism=Caenorhabditis elegans, GI71994600, Length=258, Percent_Identity=29.0697674418605, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17544670, Length=267, Percent_Identity=26.2172284644195, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17536025, Length=250, Percent_Identity=27.6, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17562906, Length=265, Percent_Identity=26.0377358490566, Blast_Score=77, Evalue=6e-15, Organism=Caenorhabditis elegans, GI17560332, Length=263, Percent_Identity=27.3764258555133, Blast_Score=77, Evalue=7e-15, Organism=Caenorhabditis elegans, GI17538182, Length=266, Percent_Identity=28.5714285714286, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17538480, Length=269, Percent_Identity=26.3940520446097, Blast_Score=75, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17565030, Length=264, Percent_Identity=27.6515151515151, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17559104, Length=268, Percent_Identity=25.7462686567164, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17551412, Length=261, Percent_Identity=26.8199233716475, Blast_Score=75, Evalue=5e-14, Organism=Caenorhabditis elegans, GI193204405, Length=265, Percent_Identity=26.7924528301887, Blast_Score=74, Evalue=6e-14, Organism=Caenorhabditis elegans, GI17562904, Length=266, Percent_Identity=26.3157894736842, Blast_Score=74, Evalue=8e-14, Organism=Caenorhabditis elegans, GI115534694, Length=240, Percent_Identity=27.5, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17560150, Length=264, Percent_Identity=26.1363636363636, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17564282, Length=246, Percent_Identity=23.5772357723577, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI193203115, Length=245, Percent_Identity=25.3061224489796, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI193203117, Length=240, Percent_Identity=25.8333333333333, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17560676, Length=257, Percent_Identity=26.4591439688716, Blast_Score=70, Evalue=9e-13, Organism=Caenorhabditis elegans, GI72000259, Length=263, Percent_Identity=25.0950570342205, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17538486, Length=263, Percent_Identity=25.8555133079848, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17560220, Length=263, Percent_Identity=24.3346007604563, Blast_Score=67, Evalue=8e-12, Organism=Caenorhabditis elegans, GI17536651, Length=250, Percent_Identity=26, Blast_Score=67, Evalue=9e-12, Organism=Caenorhabditis elegans, GI17562908, Length=265, Percent_Identity=24.1509433962264, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17531453, Length=265, Percent_Identity=24.5283018867925, Blast_Score=64, Evalue=8e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=249, Percent_Identity=28.1124497991968, Blast_Score=85, Evalue=1e-17, Organism=Saccharomyces cerevisiae, GI6322861, Length=197, Percent_Identity=30.9644670050761, Blast_Score=68, Evalue=1e-12, Organism=Drosophila melanogaster, GI24643142, Length=254, Percent_Identity=31.8897637795276, Blast_Score=99, Evalue=4e-21, Organism=Drosophila melanogaster, GI23397609, Length=257, Percent_Identity=31.1284046692607, Blast_Score=94, Evalue=9e-20, Organism=Drosophila melanogaster, GI24639444, Length=250, Percent_Identity=31.6, Blast_Score=91, Evalue=1e-18, Organism=Drosophila melanogaster, GI21355319, Length=246, Percent_Identity=28.8617886178862, Blast_Score=91, Evalue=1e-18, Organism=Drosophila melanogaster, GI21357041, Length=253, Percent_Identity=27.6679841897233, Blast_Score=89, Evalue=3e-18, Organism=Drosophila melanogaster, GI17737361, Length=264, Percent_Identity=28.4090909090909, Blast_Score=87, Evalue=8e-18, Organism=Drosophila melanogaster, GI21356301, Length=216, Percent_Identity=28.7037037037037, Blast_Score=81, Evalue=7e-16, Organism=Drosophila melanogaster, GI28571526, Length=250, Percent_Identity=24.8, Blast_Score=81, Evalue=7e-16, Organism=Drosophila melanogaster, GI24644339, Length=249, Percent_Identity=24.8995983935743, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI24649181, Length=192, Percent_Identity=29.1666666666667, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI21355631, Length=182, Percent_Identity=31.8681318681319, Blast_Score=74, Evalue=7e-14, Organism=Drosophila melanogaster, GI281364892, Length=212, Percent_Identity=25.9433962264151, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI24640492, Length=206, Percent_Identity=24.2718446601942, Blast_Score=71, Evalue=6e-13, Organism=Drosophila melanogaster, GI24581726, Length=215, Percent_Identity=26.046511627907, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI281364494, Length=204, Percent_Identity=29.9019607843137, Blast_Score=67, Evalue=9e-12, Organism=Drosophila melanogaster, GI24665243, Length=204, Percent_Identity=29.9019607843137, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI221331218, Length=198, Percent_Identity=30.8080808080808, Blast_Score=66, Evalue=3e-11, Organism=Drosophila melanogaster, GI24665247, Length=204, Percent_Identity=29.9019607843137, Blast_Score=65, Evalue=5e-11, Organism=Drosophila melanogaster, GI221331216, Length=198, Percent_Identity=30.8080808080808, Blast_Score=64, Evalue=8e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.3.1.58 [H]
Molecular weight: Translated: 26834; Mature: 26834
Theoretical pI: Translated: 10.16; Mature: 10.16
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 3.5 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 3.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKKKQTSLEGQVAVVSGGAHGIGLGIVERLLQLGAKVVASDIDRDGLAVSRERLAKSFGT CCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC SIAVQAADLSKERGAQALHRAVAKRFGPAQILVNCAGGGVIRPFLEHTPETLKATIDRNL EEEEEHHHCCHHHHHHHHHHHHHHHCCCHHEEEECCCCCEEHHHHHCCHHHHHHHHCCCH WTVIWCSRVFLPDMIGAKYGRIVNIGADSVRNGLPAHAGYNAAKGGMHGLTTGLAREFAL HHHHHHHHHHHHHHHCCCCCCEEECCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHH NGITVNTVAPCAVNTEVWAKVKKSNPRLAQAFVDVIPMGRVGEIEEVASMVGYLALPEAA CCEEEECCCCCEECHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHH FVTGQVISVNGGSAML HHCCEEEEECCCCCCC >Mature Secondary Structure MKKKQTSLEGQVAVVSGGAHGIGLGIVERLLQLGAKVVASDIDRDGLAVSRERLAKSFGT CCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC SIAVQAADLSKERGAQALHRAVAKRFGPAQILVNCAGGGVIRPFLEHTPETLKATIDRNL EEEEEHHHCCHHHHHHHHHHHHHHHCCCHHEEEECCCCCEEHHHHHCCHHHHHHHHCCCH WTVIWCSRVFLPDMIGAKYGRIVNIGADSVRNGLPAHAGYNAAKGGMHGLTTGLAREFAL HHHHHHHHHHHHHHHCCCCCCEEECCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHH NGITVNTVAPCAVNTEVWAKVKKSNPRLAQAFVDVIPMGRVGEIEEVASMVGYLALPEAA CCEEEECCCCCEECHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHH FVTGQVISVNGGSAML HHCCEEEEECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 8631713 [H]