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The map label for this gene is ytcI [H]

Identifier: 91782261

GI number: 91782261

Start: 986800

End: 988524

Strand: Direct

Name: ytcI [H]

Synonym: Bxe_A3573

Alternate gene names: 91782261

Gene position: 986800-988524 (Clockwise)

Preceding gene: 91782260

Following gene: 91782262

Centisome position: 20.16

GC content: 60.58

Gene sequence:

>1725_bases
ATGGAGACAAAATTGACAGGGTTTACGCATTCTGCACAGGCTTTCCTCGACGCGCGTGATCTGCTGGTGCGTCACCGCAC
CGACTATGAGCGCGCATATCAGGAATTTGCATGGCCGAAGCTCGACACCTTCAACTGGGCGCTCGACTATTTCGACGAAA
TGGCGCGTGGCAACGACAGCCCGGCGCTGTGGATCGTCGATGATCCTGCCAGTGCCGGAACACGGCTCACCTTCGCGCAA
ATGGCTGAGCGGTCCTCGCGCGTGGCAAATTTCCTCCGGGAGCAGGGCGTTGCTCGAGGCGACCGACTGCTGCTGATGCT
GCCCAATCGCGTTGAGTTATGGGAGGTGATGCTCGCAGCGATGAAGCTTGGCGCGGTTGTGCTGCCTGCGACAACGCAGC
TGTCATCCGATGACGTTTGTGAGCGGGTCGAGGTCGGGGCCGTGCGATTCGTCATCGTCGACGGGAGCGAGGTAGGGAAA
TTTGATGGGATCGAAGCCACTGTAAAGCGCATTGTGGTCGGCACACGAGCGGCGGTGACTCAAGGCTGGATCGATTTTGC
CTTGGCCTATGAAGCGAGCCCGGCCTTCAAACCGGACGGCCCGACGAACGCCTCCGATCCGCTACTGCTGTACTTCACAT
CGGGCACGACGTCCAGACCGAAACTTGTCGAGCATACCCATCAGAGCTATCCGGTCGGTCATCTTTCGACGATGTACTGG
ATCGGGTTGCGGCCCGGCGACGTGCACTGGAACATCAGTTCCCCCGGCTGGGCGAAGCATGCGTGGAGCTGTTTTTTTGC
GCCGTGGAATGCGGGCGCATGCGTGTTCGTCTATGACTACACGCGCTTCGTACCGAAAGATACGCTGAATGTGCTGGTGC
AATGTGGCGTCACGACACTCTGCGCGCCGCCCACAGTCTGGCGGATGCTGGTGCAGGAACCCCTCGCTTCGTATCCGGTG
AAGTTGCGGGAGATTGTCGGAGCGGGCGAACCGCTCAATCCGGAAATCATCGAGCGCGTGCGCCACGCCTGGGGTACCAC
GATTCGCGATGGTTTTGGTCAAACCGAAACCACCTGCCAGATCGGCAACTCTCCGGGCCAGCCGGTCGTCGCGGGATCGA
TGGGGCGCCCGCTGCCCGGCTACCGTATCGAGCTCGTCGACGCGGACGACCACGCCGCAAGCGAGGGAGAAATTGCCCTG
TCGCTCGCGCATCGTCCGACCGGTCTGATGACTGGCTATGCCAATAACCCGCAGGCAACGGAATACGCCATGCGCAACGG
CCTTTACCATACATCCGACGTCGCGTTGCGGCGTGAGGACGGCTACTTCGTCTACGTCGGACGAGCGGACGACGTATTCA
AGTCCTCCGACTACCGCCTGAGCCCTTTCGAACTGGAGAGCGTGCTCATCGAGCACGAGGCGATTGCCGAGGCGGCCGTC
GTGCCGAGTGCGGATGCGGTTCGTCTGTCGGTGCCGAAAGCATTCGTCATCGTGCGCCATGGCTACCAGATAGGACCGGA
ACTTGCACGCGAGGTTTTTCGCTTCTCACGCGAGAAACTCGCGCCTTATAAACGGATCCGGCGATTGCAGTTCAGCGATT
TGCCCAAGACCATCTCGGGCAAGATTCGCCGCGTTGAACTGCGGCGTCGCGAAATGGAACGCGACATGGGAGCAGGGCGC
TTCCCCGACGAATACTGGGAAGAGGACTTTCCTGAACTGCGCTGA

Upstream 100 bases:

>100_bases
GAGCGAGGTACAGCGCATGGTGATCGCGCGCCAGCTGTAGCTCGCCGCTCCGCGCCCACCGTTCAGGCAACGTAAGTAAT
AAAAGGGCGCTTGTGCGCCG

Downstream 100 bases:

>100_bases
ACATGTATCCGCATGTGGTAGTGCTGCGTGCGGTATCTCAGCATTGGCGACCGTTCCCTGGTCTACGGAGAAGCTGAATG
ATCGAGTTTGAACTTAGCCA

Product: putative AMP-binding protein

Products: AMP; diphosphate; acetyl-CoA

Alternate protein names: NA

Number of amino acids: Translated: 574; Mature: 574

Protein sequence:

>574_residues
METKLTGFTHSAQAFLDARDLLVRHRTDYERAYQEFAWPKLDTFNWALDYFDEMARGNDSPALWIVDDPASAGTRLTFAQ
MAERSSRVANFLREQGVARGDRLLLMLPNRVELWEVMLAAMKLGAVVLPATTQLSSDDVCERVEVGAVRFVIVDGSEVGK
FDGIEATVKRIVVGTRAAVTQGWIDFALAYEASPAFKPDGPTNASDPLLLYFTSGTTSRPKLVEHTHQSYPVGHLSTMYW
IGLRPGDVHWNISSPGWAKHAWSCFFAPWNAGACVFVYDYTRFVPKDTLNVLVQCGVTTLCAPPTVWRMLVQEPLASYPV
KLREIVGAGEPLNPEIIERVRHAWGTTIRDGFGQTETTCQIGNSPGQPVVAGSMGRPLPGYRIELVDADDHAASEGEIAL
SLAHRPTGLMTGYANNPQATEYAMRNGLYHTSDVALRREDGYFVYVGRADDVFKSSDYRLSPFELESVLIEHEAIAEAAV
VPSADAVRLSVPKAFVIVRHGYQIGPELAREVFRFSREKLAPYKRIRRLQFSDLPKTISGKIRRVELRRREMERDMGAGR
FPDEYWEEDFPELR

Sequences:

>Translated_574_residues
METKLTGFTHSAQAFLDARDLLVRHRTDYERAYQEFAWPKLDTFNWALDYFDEMARGNDSPALWIVDDPASAGTRLTFAQ
MAERSSRVANFLREQGVARGDRLLLMLPNRVELWEVMLAAMKLGAVVLPATTQLSSDDVCERVEVGAVRFVIVDGSEVGK
FDGIEATVKRIVVGTRAAVTQGWIDFALAYEASPAFKPDGPTNASDPLLLYFTSGTTSRPKLVEHTHQSYPVGHLSTMYW
IGLRPGDVHWNISSPGWAKHAWSCFFAPWNAGACVFVYDYTRFVPKDTLNVLVQCGVTTLCAPPTVWRMLVQEPLASYPV
KLREIVGAGEPLNPEIIERVRHAWGTTIRDGFGQTETTCQIGNSPGQPVVAGSMGRPLPGYRIELVDADDHAASEGEIAL
SLAHRPTGLMTGYANNPQATEYAMRNGLYHTSDVALRREDGYFVYVGRADDVFKSSDYRLSPFELESVLIEHEAIAEAAV
VPSADAVRLSVPKAFVIVRHGYQIGPELAREVFRFSREKLAPYKRIRRLQFSDLPKTISGKIRRVELRRREMERDMGAGR
FPDEYWEEDFPELR
>Mature_574_residues
METKLTGFTHSAQAFLDARDLLVRHRTDYERAYQEFAWPKLDTFNWALDYFDEMARGNDSPALWIVDDPASAGTRLTFAQ
MAERSSRVANFLREQGVARGDRLLLMLPNRVELWEVMLAAMKLGAVVLPATTQLSSDDVCERVEVGAVRFVIVDGSEVGK
FDGIEATVKRIVVGTRAAVTQGWIDFALAYEASPAFKPDGPTNASDPLLLYFTSGTTSRPKLVEHTHQSYPVGHLSTMYW
IGLRPGDVHWNISSPGWAKHAWSCFFAPWNAGACVFVYDYTRFVPKDTLNVLVQCGVTTLCAPPTVWRMLVQEPLASYPV
KLREIVGAGEPLNPEIIERVRHAWGTTIRDGFGQTETTCQIGNSPGQPVVAGSMGRPLPGYRIELVDADDHAASEGEIAL
SLAHRPTGLMTGYANNPQATEYAMRNGLYHTSDVALRREDGYFVYVGRADDVFKSSDYRLSPFELESVLIEHEAIAEAAV
VPSADAVRLSVPKAFVIVRHGYQIGPELAREVFRFSREKLAPYKRIRRLQFSDLPKTISGKIRRVELRRREMERDMGAGR
FPDEYWEEDFPELR

Specific function: Enables The Cell To Use Acetate During Aerobic Growth To Generate Energy Via The Tca Cycle, And Biosynthetic Compounds Via The Glyoxylate Shunt. Acetylates Chey, The Response Regulator Involved In Flagellar Movement And Chemotaxis. [C]

COG id: COG0365

COG function: function code I; Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]

Homologues:

Organism=Homo sapiens, GI42544132, Length=555, Percent_Identity=36.036036036036, Blast_Score=361, Evalue=1e-99,
Organism=Homo sapiens, GI122937307, Length=534, Percent_Identity=37.8277153558052, Blast_Score=328, Evalue=6e-90,
Organism=Homo sapiens, GI38505220, Length=529, Percent_Identity=37.8071833648393, Blast_Score=328, Evalue=7e-90,
Organism=Homo sapiens, GI58082049, Length=529, Percent_Identity=33.648393194707, Blast_Score=293, Evalue=3e-79,
Organism=Homo sapiens, GI157311624, Length=529, Percent_Identity=33.4593572778828, Blast_Score=290, Evalue=2e-78,
Organism=Homo sapiens, GI157311622, Length=529, Percent_Identity=33.4593572778828, Blast_Score=290, Evalue=2e-78,
Organism=Homo sapiens, GI115511026, Length=553, Percent_Identity=30.379746835443, Blast_Score=253, Evalue=5e-67,
Organism=Homo sapiens, GI42544134, Length=385, Percent_Identity=32.4675324675325, Blast_Score=229, Evalue=7e-60,
Organism=Homo sapiens, GI195947378, Length=437, Percent_Identity=28.8329519450801, Blast_Score=187, Evalue=3e-47,
Organism=Homo sapiens, GI8923896, Length=606, Percent_Identity=28.3828382838284, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI13375727, Length=547, Percent_Identity=27.0566727605119, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI28416953, Length=577, Percent_Identity=26.8630849220104, Blast_Score=139, Evalue=1e-32,
Organism=Homo sapiens, GI253970489, Length=391, Percent_Identity=31.2020460358056, Blast_Score=136, Evalue=7e-32,
Organism=Homo sapiens, GI31982927, Length=547, Percent_Identity=22.3034734917733, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI156151445, Length=529, Percent_Identity=24.5746691871456, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI187761345, Length=391, Percent_Identity=23.7851662404092, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI187761343, Length=391, Percent_Identity=23.7851662404092, Blast_Score=82, Evalue=2e-15,
Organism=Escherichia coli, GI1790505, Length=567, Percent_Identity=29.8059964726631, Blast_Score=178, Evalue=1e-45,
Organism=Escherichia coli, GI221142682, Length=514, Percent_Identity=25.875486381323, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI1788107, Length=552, Percent_Identity=25.1811594202899, Blast_Score=126, Evalue=5e-30,
Organism=Escherichia coli, GI1786529, Length=527, Percent_Identity=25.8064516129032, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI145693145, Length=523, Percent_Identity=24.6653919694073, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1786810, Length=551, Percent_Identity=23.956442831216, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1788595, Length=475, Percent_Identity=24, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1786801, Length=463, Percent_Identity=25.0539956803456, Blast_Score=79, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI71983001, Length=554, Percent_Identity=29.6028880866426, Blast_Score=150, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI71982997, Length=554, Percent_Identity=29.6028880866426, Blast_Score=150, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17531443, Length=495, Percent_Identity=24.8484848484848, Blast_Score=112, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI17559526, Length=568, Percent_Identity=24.1197183098592, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71996755, Length=490, Percent_Identity=24.6938775510204, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17557194, Length=509, Percent_Identity=23.7721021611002, Blast_Score=94, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71985884, Length=368, Percent_Identity=27.1739130434783, Blast_Score=92, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI71994703, Length=524, Percent_Identity=21.9465648854962, Blast_Score=90, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71994694, Length=524, Percent_Identity=21.9465648854962, Blast_Score=90, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71994690, Length=524, Percent_Identity=21.9465648854962, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI32563687, Length=488, Percent_Identity=21.7213114754098, Blast_Score=89, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17558820, Length=505, Percent_Identity=21.5841584158416, Blast_Score=88, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17538037, Length=521, Percent_Identity=22.0729366602687, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17560140, Length=512, Percent_Identity=21.6796875, Blast_Score=77, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6323182, Length=569, Percent_Identity=27.5922671353251, Blast_Score=151, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6319264, Length=572, Percent_Identity=26.2237762237762, Blast_Score=137, Evalue=5e-33,
Organism=Saccharomyces cerevisiae, GI6319699, Length=347, Percent_Identity=25.3602305475504, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24667955, Length=593, Percent_Identity=27.6559865092749, Blast_Score=171, Evalue=1e-42,
Organism=Drosophila melanogaster, GI62472339, Length=542, Percent_Identity=28.9667896678967, Blast_Score=166, Evalue=4e-41,
Organism=Drosophila melanogaster, GI24667959, Length=502, Percent_Identity=28.8844621513944, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI21355225, Length=536, Percent_Identity=27.6119402985075, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI21355181, Length=496, Percent_Identity=24.7983870967742, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI18859661, Length=511, Percent_Identity=24.853228962818, Blast_Score=115, Evalue=6e-26,
Organism=Drosophila melanogaster, GI24581924, Length=536, Percent_Identity=23.8805970149254, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI21356947, Length=488, Percent_Identity=22.5409836065574, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24653035, Length=498, Percent_Identity=23.0923694779116, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI161076582, Length=516, Percent_Identity=22.2868217054264, Blast_Score=73, Evalue=6e-13,
Organism=Drosophila melanogaster, GI20130357, Length=511, Percent_Identity=22.3091976516634, Blast_Score=73, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020845
- InterPro:   IPR000873 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: 6.2.1.1

Molecular weight: Translated: 64359; Mature: 64359

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METKLTGFTHSAQAFLDARDLLVRHRTDYERAYQEFAWPKLDTFNWALDYFDEMARGNDS
CCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCC
PALWIVDDPASAGTRLTFAQMAERSSRVANFLREQGVARGDRLLLMLPNRVELWEVMLAA
CEEEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHH
MKLGAVVLPATTQLSSDDVCERVEVGAVRFVIVDGSEVGKFDGIEATVKRIVVGTRAAVT
HHHCEEEECCCCCCCCHHHHHHHCCCEEEEEEEECCCCCCCCCHHHHHHHHHHCCHHHHH
QGWIDFALAYEASPAFKPDGPTNASDPLLLYFTSGTTSRPKLVEHTHQSYPVGHLSTMYW
HHHHHEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHCCCCCCCCCCCEEEE
IGLRPGDVHWNISSPGWAKHAWSCFFAPWNAGACVFVYDYTRFVPKDTLNVLVQCGVTTL
EECCCCCEEEECCCCCCCCCCEEEEECCCCCCCEEEEEECHHHCCHHHHHHHHHCCCHHH
CAPPTVWRMLVQEPLASYPVKLREIVGAGEPLNPEIIERVRHAWGTTIRDGFGQTETTCQ
CCCHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHCCCCCCCCEEE
IGNSPGQPVVAGSMGRPLPGYRIELVDADDHAASEGEIALSLAHRPTGLMTGYANNPQAT
ECCCCCCCEEECCCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCEEECCCCCCCHH
EYAMRNGLYHTSDVALRREDGYFVYVGRADDVFKSSDYRLSPFELESVLIEHEAIAEAAV
HHHHHCCCCCCCCEEEEECCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
VPSADAVRLSVPKAFVIVRHGYQIGPELAREVFRFSREKLAPYKRIRRLQFSDLPKTISG
CCCCCCEEEECCEEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHC
KIRRVELRRREMERDMGAGRFPDEYWEEDFPELR
HHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCC
>Mature Secondary Structure
METKLTGFTHSAQAFLDARDLLVRHRTDYERAYQEFAWPKLDTFNWALDYFDEMARGNDS
CCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCC
PALWIVDDPASAGTRLTFAQMAERSSRVANFLREQGVARGDRLLLMLPNRVELWEVMLAA
CEEEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHH
MKLGAVVLPATTQLSSDDVCERVEVGAVRFVIVDGSEVGKFDGIEATVKRIVVGTRAAVT
HHHCEEEECCCCCCCCHHHHHHHCCCEEEEEEEECCCCCCCCCHHHHHHHHHHCCHHHHH
QGWIDFALAYEASPAFKPDGPTNASDPLLLYFTSGTTSRPKLVEHTHQSYPVGHLSTMYW
HHHHHEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHCCCCCCCCCCCEEEE
IGLRPGDVHWNISSPGWAKHAWSCFFAPWNAGACVFVYDYTRFVPKDTLNVLVQCGVTTL
EECCCCCEEEECCCCCCCCCCEEEEECCCCCCCEEEEEECHHHCCHHHHHHHHHCCCHHH
CAPPTVWRMLVQEPLASYPVKLREIVGAGEPLNPEIIERVRHAWGTTIRDGFGQTETTCQ
CCCHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHCCCCCCCCEEE
IGNSPGQPVVAGSMGRPLPGYRIELVDADDHAASEGEIALSLAHRPTGLMTGYANNPQAT
ECCCCCCCEEECCCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCEEECCCCCCCHH
EYAMRNGLYHTSDVALRREDGYFVYVGRADDVFKSSDYRLSPFELESVLIEHEAIAEAAV
HHHHHCCCCCCCCEEEEECCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
VPSADAVRLSVPKAFVIVRHGYQIGPELAREVFRFSREKLAPYKRIRRLQFSDLPKTISG
CCCCCCEEEECCEEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHC
KIRRVELRRREMERDMGAGRFPDEYWEEDFPELR
HHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; acetate; CoA

Specific reaction: ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA

General reaction: Acid-thiol ligation [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]