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The map label for this gene is ttuB [H]

Identifier: 91782237

GI number: 91782237

Start: 957280

End: 958629

Strand: Direct

Name: ttuB [H]

Synonym: Bxe_A3598

Alternate gene names: 91782237

Gene position: 957280-958629 (Clockwise)

Preceding gene: 91782236

Following gene: 91782238

Centisome position: 19.55

GC content: 59.19

Gene sequence:

>1350_bases
ATGAAAGCCGATGAAGGCATGGTCGCCGAGATCGAACGGCGTATCGTTTCGAAGGTGAACTGGCGGGTGATGCTGATTTT
CATGCTGGGGTACCTGATTTCCTTCGTGGACCGGGCAAATCTGGGAGTCCTCGCCGGTCCCATCTCCAAGGACCTGCATC
TGTCTGCGGCAAGCTTTGGTCTTGCGGCTGGTGTCTTTTATATTGGCTATTTGCTGTTCGCCATTCCATCCAATATGGCG
ATCGTGCGTTTCGGCGGCCGCTTCTGGATGGGTTGCATCATGGCAGGTTGGGGGTTGGTATGTTTCGGGCTGGCAGCCGC
ACGAAGCGAAACTTGGCTTCTCGCGTGTCGCATTCTGCTGGGCGTGACCGAAGCGGGTTTCTATCCTGGTGCGATGTTTC
TGATGACGTTGTGGTATCCGCCGCGCGCACTGGCTAAAGCCTACGCCACCTATACCGCATTCACGCCGCTCGCACTCGTA
TTCGGCGCGTTGGCAACCTCCGCGTTGCTTTCCCTTCACGGCTTCGGACCCATTGCCGATTGGCGTCTGGTCTTCGTACT
CGAAGGCATTCCAGCGTTTCTGCTTGGCATCTATACGTGGCTCTCATTGCCGTCGCGTCCCAAGGATGCGAAATGGTTGA
GCGCTGAGGAAAAGGCGTATCTCGCCTCGCAGATTCCGGAAGTCGCGCGAGGCCAACGGGGAGATGCGACGCGTGCCTTG
GTCAAGACGTTGAAAGATCCCTTTTCGTGGCTTTTCGCGTTGCTCTATTTCCTGATGCTGCTTGGCTACTGGGGACTTAT
CTATTTCATGCCCCGTATTCTGCAGAGCCGGTTTCACACCGACCCGGTGCACGCGGGCTTCATTTCCACATTGCCGTGGC
TCTTTGCCTGCGTGCTGATCTACGCGATGGGCAAGAGCTCGGCGATGACGGGCGAGCGTCGCTGGCACATGGCGATCGGT
CTGATTCTTTCGGGCGCGGGCCTGTATCTGGCAGCGTCGACCGACTCCAGTGTGCTGACGCTTCTTGGCCTGTGTCTCGG
CGCCGGCGGCGCCCCCGCTGCGGCTGCATTCTTCTGGACAATGCCTGCGACTGTGTTCGCCGGCGCCACCGTCGCGATCG
CAATGGCAATGGTCAACTCGGTGGGCAATCTCAGCGGCTTCGCTGGGCCTTGGGTGATCGGAGTGTTGACGGATCTCTCC
GGTGACAGCCGGCTTGCCCTGTACGTTCTGGCCTGCATGTGCATCCTGGCCGCAGCCCTTGCATTCACGATGGCGTCCAT
CGTGCAGCGGCGTGGCGCCTCATGGGGTGTGACTGCGGATAAATCGTTGTCTGGCGCGACAGGACATTGA

Upstream 100 bases:

>100_bases
CATTGCAAACAGGCAGATCAACGACGATATTCAAAGAAAAACACTTGCCGGTGCCATGCGCCTTCGGGCGCCGAAGCGCT
GGCTTCCAATGGAGACGAGT

Downstream 100 bases:

>100_bases
GGCGCACATTGTTTAGCCGATGTTCGTCACATCGCGTTAATGATCGGGAGCCGGCTGGCCGGCCCCCGATTGCAGCCGCA
GCGAGCGTCGAAAATGATCC

Product: major facilitator superfamily metabolite/H(+) symporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MKADEGMVAEIERRIVSKVNWRVMLIFMLGYLISFVDRANLGVLAGPISKDLHLSAASFGLAAGVFYIGYLLFAIPSNMA
IVRFGGRFWMGCIMAGWGLVCFGLAAARSETWLLACRILLGVTEAGFYPGAMFLMTLWYPPRALAKAYATYTAFTPLALV
FGALATSALLSLHGFGPIADWRLVFVLEGIPAFLLGIYTWLSLPSRPKDAKWLSAEEKAYLASQIPEVARGQRGDATRAL
VKTLKDPFSWLFALLYFLMLLGYWGLIYFMPRILQSRFHTDPVHAGFISTLPWLFACVLIYAMGKSSAMTGERRWHMAIG
LILSGAGLYLAASTDSSVLTLLGLCLGAGGAPAAAAFFWTMPATVFAGATVAIAMAMVNSVGNLSGFAGPWVIGVLTDLS
GDSRLALYVLACMCILAAALAFTMASIVQRRGASWGVTADKSLSGATGH

Sequences:

>Translated_449_residues
MKADEGMVAEIERRIVSKVNWRVMLIFMLGYLISFVDRANLGVLAGPISKDLHLSAASFGLAAGVFYIGYLLFAIPSNMA
IVRFGGRFWMGCIMAGWGLVCFGLAAARSETWLLACRILLGVTEAGFYPGAMFLMTLWYPPRALAKAYATYTAFTPLALV
FGALATSALLSLHGFGPIADWRLVFVLEGIPAFLLGIYTWLSLPSRPKDAKWLSAEEKAYLASQIPEVARGQRGDATRAL
VKTLKDPFSWLFALLYFLMLLGYWGLIYFMPRILQSRFHTDPVHAGFISTLPWLFACVLIYAMGKSSAMTGERRWHMAIG
LILSGAGLYLAASTDSSVLTLLGLCLGAGGAPAAAAFFWTMPATVFAGATVAIAMAMVNSVGNLSGFAGPWVIGVLTDLS
GDSRLALYVLACMCILAAALAFTMASIVQRRGASWGVTADKSLSGATGH
>Mature_449_residues
MKADEGMVAEIERRIVSKVNWRVMLIFMLGYLISFVDRANLGVLAGPISKDLHLSAASFGLAAGVFYIGYLLFAIPSNMA
IVRFGGRFWMGCIMAGWGLVCFGLAAARSETWLLACRILLGVTEAGFYPGAMFLMTLWYPPRALAKAYATYTAFTPLALV
FGALATSALLSLHGFGPIADWRLVFVLEGIPAFLLGIYTWLSLPSRPKDAKWLSAEEKAYLASQIPEVARGQRGDATRAL
VKTLKDPFSWLFALLYFLMLLGYWGLIYFMPRILQSRFHTDPVHAGFISTLPWLFACVLIYAMGKSSAMTGERRWHMAIG
LILSGAGLYLAASTDSSVLTLLGLCLGAGGAPAAAAFFWTMPATVFAGATVAIAMAMVNSVGNLSGFAGPWVIGVLTDLS
GDSRLALYVLACMCILAAALAFTMASIVQRRGASWGVTADKSLSGATGH

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=412, Percent_Identity=32.0388349514563, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI2367379, Length=452, Percent_Identity=23.6725663716814, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1789515, Length=442, Percent_Identity=22.3981900452489, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI87082320, Length=415, Percent_Identity=22.1686746987952, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1789152, Length=458, Percent_Identity=20.3056768558952, Blast_Score=62, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6319876, Length=470, Percent_Identity=21.9148936170213, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6321698, Length=296, Percent_Identity=23.9864864864865, Blast_Score=82, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6322025, Length=263, Percent_Identity=20.1520912547529, Blast_Score=77, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6323032, Length=253, Percent_Identity=25.296442687747, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322612, Length=433, Percent_Identity=22.1709006928406, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24583789, Length=370, Percent_Identity=21.0810810810811, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24655271, Length=437, Percent_Identity=22.1967963386728, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI20130135, Length=437, Percent_Identity=22.1967963386728, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48265; Mature: 48265

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKADEGMVAEIERRIVSKVNWRVMLIFMLGYLISFVDRANLGVLAGPISKDLHLSAASFG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHH
LAAGVFYIGYLLFAIPSNMAIVRFGGRFWMGCIMAGWGLVCFGLAAARSETWLLACRILL
HHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
GVTEAGFYPGAMFLMTLWYPPRALAKAYATYTAFTPLALVFGALATSALLSLHGFGPIAD
HHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
WRLVFVLEGIPAFLLGIYTWLSLPSRPKDAKWLSAEEKAYLASQIPEVARGQRGDATRAL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCHHHHCCCCCCHHHHH
VKTLKDPFSWLFALLYFLMLLGYWGLIYFMPRILQSRFHTDPVHAGFISTLPWLFACVLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
YAMGKSSAMTGERRWHMAIGLILSGAGLYLAASTDSSVLTLLGLCLGAGGAPAAAAFFWT
HHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHH
MPATVFAGATVAIAMAMVNSVGNLSGFAGPWVIGVLTDLSGDSRLALYVLACMCILAAAL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
AFTMASIVQRRGASWGVTADKSLSGATGH
HHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKADEGMVAEIERRIVSKVNWRVMLIFMLGYLISFVDRANLGVLAGPISKDLHLSAASFG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHH
LAAGVFYIGYLLFAIPSNMAIVRFGGRFWMGCIMAGWGLVCFGLAAARSETWLLACRILL
HHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
GVTEAGFYPGAMFLMTLWYPPRALAKAYATYTAFTPLALVFGALATSALLSLHGFGPIAD
HHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
WRLVFVLEGIPAFLLGIYTWLSLPSRPKDAKWLSAEEKAYLASQIPEVARGQRGDATRAL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCHHHHCCCCCCHHHHH
VKTLKDPFSWLFALLYFLMLLGYWGLIYFMPRILQSRFHTDPVHAGFISTLPWLFACVLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
YAMGKSSAMTGERRWHMAIGLILSGAGLYLAASTDSSVLTLLGLCLGAGGAPAAAAFFWT
HHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHH
MPATVFAGATVAIAMAMVNSVGNLSGFAGPWVIGVLTDLSGDSRLALYVLACMCILAAAL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
AFTMASIVQRRGASWGVTADKSLSGATGH
HHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]