Definition Burkholderia xenovorans LB400 chromosome 1, complete sequence.
Accession NC_007951
Length 4,895,836

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The map label for this gene is livF [H]

Identifier: 91782126

GI number: 91782126

Start: 836979

End: 837713

Strand: Reverse

Name: livF [H]

Synonym: Bxe_A3709

Alternate gene names: 91782126

Gene position: 837713-836979 (Counterclockwise)

Preceding gene: 91782127

Following gene: 91782125

Centisome position: 17.11

GC content: 63.27

Gene sequence:

>735_bases
ATGTTATCGATCAGAAATCTGCATGCGGGCTACGGCAAAGTCAAAGTGCTGCACGGCATTTCGATCGACGTGCCGAAAGC
ATCCGTCGTCACGCTGATCGGCTCGAACGGCGCCGGCAAAACCACGACCATGCGAGCGATCTCTGGCATGATCCGGCCGA
GTGCCGGCGAGATCACGATGGGCGTCGGCGCGGACGCGAAGCGCATCGACGCACTGGAATCGCACCGCATCGCACGGCTC
GGACTCGCGCATTCGCCGGAAGGCAGGCGCGTGTTCGCGACGATGAGCGTGACCGACAACCTGCTACTGGGCGCCTTCCC
GCGTCTGACCTCGGCGCGGCCGCGCGGCGACGTGAAGGCCGATCTGGAACGCGCAATCGAGATGTTTCCGCGGCTCAAGG
AGCGCCGCCATCAACTCGCCGGCACGCTCTCCGGCGGCGAGCAGCAGATGCTGGCAATGGCGCGCGCGATCATGATGAAC
CCGGAGCTGGTGCTGCTCGACGAACCGTCGATGGGACTCGCGCCCATTCTGGTCGAAGAAGTGTTCCGCATTATCGGGAA
TCTGAAAAGCCAGGGCGTCACCATGTTGCTGGTCGAACAGTTCGCCGCGGCCGCGCTCAATGTGGCCGATTATGGTTATG
TGCTCGAGAACGGCAGGATCGCAGCGCATGGACCCGCAGCGGAGTTGCGCAACGATCCTTCGGTGAAGGCCGCGTATCTC
GGCGCGAGTCATTGA

Upstream 100 bases:

>100_bases
CCGATATTCAGTCCAACGAAAAAGTCATCGAAGCCTATCTCGGCGGCCAGCCTGCCGGCCAGACGGCATGAGCTCGCCGG
GCGCCTTTACAGGAACAGAC

Downstream 100 bases:

>100_bases
GGCGCACACGACAGTCGGGCTGGCGTGGTGCCGATGTGTTTCGCGTTTCGCGGTGTGGGGTGTGGGCCGGCGGGTGATAT
CGGGTCGATCACTTCCACCG

Product: branched chain amino acid ABC transporter ATPase

Products: ADP; phosphate; L-leucine [Cytoplasm]; ADP; L-valine [Cytoplasm]; L-iso-leucine [Cytoplasm] [C]

Alternate protein names: LIV-I protein F [H]

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MLSIRNLHAGYGKVKVLHGISIDVPKASVVTLIGSNGAGKTTTMRAISGMIRPSAGEITMGVGADAKRIDALESHRIARL
GLAHSPEGRRVFATMSVTDNLLLGAFPRLTSARPRGDVKADLERAIEMFPRLKERRHQLAGTLSGGEQQMLAMARAIMMN
PELVLLDEPSMGLAPILVEEVFRIIGNLKSQGVTMLLVEQFAAAALNVADYGYVLENGRIAAHGPAAELRNDPSVKAAYL
GASH

Sequences:

>Translated_244_residues
MLSIRNLHAGYGKVKVLHGISIDVPKASVVTLIGSNGAGKTTTMRAISGMIRPSAGEITMGVGADAKRIDALESHRIARL
GLAHSPEGRRVFATMSVTDNLLLGAFPRLTSARPRGDVKADLERAIEMFPRLKERRHQLAGTLSGGEQQMLAMARAIMMN
PELVLLDEPSMGLAPILVEEVFRIIGNLKSQGVTMLLVEQFAAAALNVADYGYVLENGRIAAHGPAAELRNDPSVKAAYL
GASH
>Mature_244_residues
MLSIRNLHAGYGKVKVLHGISIDVPKASVVTLIGSNGAGKTTTMRAISGMIRPSAGEITMGVGADAKRIDALESHRIARL
GLAHSPEGRRVFATMSVTDNLLLGAFPRLTSARPRGDVKADLERAIEMFPRLKERRHQLAGTLSGGEQQMLAMARAIMMN
PELVLLDEPSMGLAPILVEEVFRIIGNLKSQGVTMLLVEQFAAAALNVADYGYVLENGRIAAHGPAAELRNDPSVKAAYL
GASH

Specific function: Component of the leucine-specific transport system [H]

COG id: COG0410

COG function: function code E; ABC-type branched-chain amino acid transport systems, ATPase component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI27477115, Length=233, Percent_Identity=27.8969957081545, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI153792144, Length=233, Percent_Identity=28.3261802575107, Blast_Score=88, Evalue=6e-18,
Organism=Homo sapiens, GI27436953, Length=233, Percent_Identity=24.8927038626609, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI45446740, Length=209, Percent_Identity=28.7081339712919, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI47078218, Length=209, Percent_Identity=28.7081339712919, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI6005701, Length=214, Percent_Identity=28.0373831775701, Blast_Score=81, Evalue=7e-16,
Organism=Homo sapiens, GI4505771, Length=219, Percent_Identity=29.6803652968037, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI9961252, Length=219, Percent_Identity=29.6803652968037, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI42741659, Length=221, Percent_Identity=29.4117647058824, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI9961250, Length=225, Percent_Identity=28.8888888888889, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI148612844, Length=225, Percent_Identity=30.6666666666667, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI255708477, Length=225, Percent_Identity=30.6666666666667, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI105990541, Length=212, Percent_Identity=25, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI21536376, Length=236, Percent_Identity=26.6949152542373, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI27881501, Length=223, Percent_Identity=27.3542600896861, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI30795238, Length=223, Percent_Identity=27.3542600896861, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI31657092, Length=220, Percent_Identity=25.9090909090909, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI171184400, Length=246, Percent_Identity=26.4227642276423, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI27262624, Length=220, Percent_Identity=24.5454545454545, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI27262626, Length=220, Percent_Identity=24.5454545454545, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI42490749, Length=237, Percent_Identity=29.535864978903, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI150417984, Length=239, Percent_Identity=27.1966527196653, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI87082268, Length=241, Percent_Identity=46.4730290456432, Blast_Score=214, Evalue=6e-57,
Organism=Escherichia coli, GI1789864, Length=255, Percent_Identity=30.1960784313725, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1789593, Length=244, Percent_Identity=32.7868852459016, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1788225, Length=238, Percent_Identity=33.6134453781513, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1787029, Length=239, Percent_Identity=30.5439330543933, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1787792, Length=251, Percent_Identity=27.8884462151394, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1786872, Length=236, Percent_Identity=30.5084745762712, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1789672, Length=239, Percent_Identity=28.4518828451883, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1788761, Length=239, Percent_Identity=30.1255230125523, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1790162, Length=246, Percent_Identity=28.8617886178862, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI87081709, Length=253, Percent_Identity=28.4584980237154, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1787089, Length=244, Percent_Identity=26.6393442622951, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788644, Length=244, Percent_Identity=30.327868852459, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1789991, Length=237, Percent_Identity=26.1603375527426, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1790190, Length=238, Percent_Identity=25.6302521008403, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1790739, Length=235, Percent_Identity=31.063829787234, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1789586, Length=238, Percent_Identity=29.8319327731092, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1788897, Length=214, Percent_Identity=28.5046728971963, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI1788472, Length=237, Percent_Identity=27.0042194092827, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790525, Length=242, Percent_Identity=26.0330578512397, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI48994943, Length=228, Percent_Identity=30.7017543859649, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI48995001, Length=232, Percent_Identity=26.7241379310345, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87081782, Length=182, Percent_Identity=31.8681318681319, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1786398, Length=237, Percent_Identity=24.4725738396624, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788450, Length=231, Percent_Identity=30.3030303030303, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI87081791, Length=248, Percent_Identity=25.8064516129032, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787105, Length=232, Percent_Identity=29.3103448275862, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI48994997, Length=243, Percent_Identity=27.5720164609054, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790544, Length=247, Percent_Identity=27.5303643724696, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1786253, Length=226, Percent_Identity=28.3185840707965, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1787712, Length=247, Percent_Identity=27.9352226720648, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI87081834, Length=206, Percent_Identity=29.6116504854369, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1786345, Length=240, Percent_Identity=27.9166666666667, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1789032, Length=242, Percent_Identity=24.7933884297521, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790467, Length=247, Percent_Identity=26.7206477732794, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1786319, Length=228, Percent_Identity=26.7543859649123, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1789873, Length=199, Percent_Identity=28.643216080402, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1787164, Length=211, Percent_Identity=29.3838862559242, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788165, Length=176, Percent_Identity=27.8409090909091, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787370, Length=221, Percent_Identity=26.6968325791855, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI87082267, Length=237, Percent_Identity=26.5822784810127, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786803, Length=231, Percent_Identity=25.5411255411255, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1786703, Length=191, Percent_Identity=27.2251308900524, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1786563, Length=173, Percent_Identity=30.635838150289, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1788053, Length=172, Percent_Identity=30.2325581395349, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788210, Length=209, Percent_Identity=29.1866028708134, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1787758, Length=249, Percent_Identity=23.2931726907631, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1787112, Length=233, Percent_Identity=26.6094420600858, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1786981, Length=224, Percent_Identity=31.25, Blast_Score=61, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17510237, Length=221, Percent_Identity=28.9592760180996, Blast_Score=89, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71983516, Length=216, Percent_Identity=29.1666666666667, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71983510, Length=216, Percent_Identity=29.1666666666667, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71983523, Length=216, Percent_Identity=29.1666666666667, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI115533608, Length=239, Percent_Identity=28.0334728033473, Blast_Score=78, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17565586, Length=221, Percent_Identity=27.1493212669683, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI193211015, Length=226, Percent_Identity=27.4336283185841, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193211017, Length=226, Percent_Identity=27.4336283185841, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI115534520, Length=235, Percent_Identity=25.9574468085106, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71984940, Length=216, Percent_Identity=28.2407407407407, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71996809, Length=226, Percent_Identity=27.4336283185841, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI193208177, Length=238, Percent_Identity=27.3109243697479, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71996550, Length=245, Percent_Identity=25.7142857142857, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI212646699, Length=222, Percent_Identity=26.5765765765766, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25146777, Length=237, Percent_Identity=27.0042194092827, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17558664, Length=164, Percent_Identity=31.0975609756098, Blast_Score=64, Evalue=9e-11,
Organism=Drosophila melanogaster, GI221512771, Length=230, Percent_Identity=29.1304347826087, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24666092, Length=223, Percent_Identity=28.2511210762332, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24643674, Length=229, Percent_Identity=27.5109170305677, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI85725262, Length=199, Percent_Identity=27.6381909547739, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24650853, Length=236, Percent_Identity=27.1186440677966, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24650855, Length=236, Percent_Identity=27.1186440677966, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI281362751, Length=204, Percent_Identity=28.4313725490196, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24648314, Length=233, Percent_Identity=25.7510729613734, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI28574533, Length=220, Percent_Identity=25.4545454545455, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24582014, Length=197, Percent_Identity=27.4111675126904, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24582012, Length=197, Percent_Identity=27.4111675126904, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI19920532, Length=218, Percent_Identity=27.0642201834862, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24580930, Length=218, Percent_Identity=27.0642201834862, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24662800, Length=222, Percent_Identity=25.2252252252252, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28574150, Length=219, Percent_Identity=26.027397260274, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI116007328, Length=219, Percent_Identity=26.027397260274, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281363262, Length=237, Percent_Identity=28.2700421940928, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24653245, Length=237, Percent_Identity=28.2700421940928, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI28574744, Length=221, Percent_Identity=27.6018099547511, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI28571209, Length=216, Percent_Identity=25.462962962963, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 26040; Mature: 26040

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MLSIRNLHAGYGKVKVLHGISIDVPKASVVTLIGSNGAGKTTTMRAISGMIRPSAGEITM
CCCCCCCCCCCCEEEEEECCEECCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCCEEE
GVGADAKRIDALESHRIARLGLAHSPEGRRVFATMSVTDNLLLGAFPRLTSARPRGDVKA
ECCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHCCCCCCCCCCCCCHHH
DLERAIEMFPRLKERRHQLAGTLSGGEQQMLAMARAIMMNPELVLLDEPSMGLAPILVEE
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHH
VFRIIGNLKSQGVTMLLVEQFAAAALNVADYGYVLENGRIAAHGPAAELRNDPSVKAAYL
HHHHHHCHHHCCCHHHHHHHHHHHHHHHHHCCEEEECCEEEECCCHHHHCCCCCCEEEEC
GASH
CCCC
>Mature Secondary Structure
MLSIRNLHAGYGKVKVLHGISIDVPKASVVTLIGSNGAGKTTTMRAISGMIRPSAGEITM
CCCCCCCCCCCCEEEEEECCEECCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCCEEE
GVGADAKRIDALESHRIARLGLAHSPEGRRVFATMSVTDNLLLGAFPRLTSARPRGDVKA
ECCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHCCCCCCCCCCCCCHHH
DLERAIEMFPRLKERRHQLAGTLSGGEQQMLAMARAIMMNPELVLLDEPSMGLAPILVEE
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHH
VFRIIGNLKSQGVTMLLVEQFAAAALNVADYGYVLENGRIAAHGPAAELRNDPSVKAAYL
HHHHHHCHHHCCCHHHHHHHHHHHHHHHHHCCEEEECCEEEECCCHHHHCCCCCCEEEEC
GASH
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-leucine [Periplasm]; H2O; ATP; L-valine [Periplasm]; L-iso-leucine [Periplasm] [C]

Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2195019; 8041620; 9278503 [H]