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The map label for this gene is wecB [H]

Identifier: 91782102

GI number: 91782102

Start: 811192

End: 812301

Strand: Direct

Name: wecB [H]

Synonym: Bxe_A3733

Alternate gene names: 91782102

Gene position: 811192-812301 (Clockwise)

Preceding gene: 91782100

Following gene: 91782104

Centisome position: 16.57

GC content: 54.14

Gene sequence:

>1110_bases
TTGAGAAAACGTAAAATCATTGTCACTGTCGGCACCCGCCCCGAAGCAGTGAAGATGGCGCCGCTGATCAAGCAACTGCA
ACATGAAGAATGGGCAGACTGCCGTGTGCTCGCGACGGCGCAACACCGGGGTATGCTTGATCAAGTACTGCGTCTGTTCG
AGATCAAACCAGACATTGACTTGGATATCATGCAGCCGAACCAGTCTTTGCCCACGCTAACCTCACGACTAATAACGAAG
TTAGACGAGGTACTCGCGACTGAGGAACCAGATGTTCTTCTTGCGCAAGGGGACACGACTACAGTCCTGACGGCAGCGCT
AGCGTGCTTCTACCGGCGAGTACCTTTCGGGCACGTCGAAGCGGGTCTTCGAACAGGCGATCTTTCGAATCCGTTTCCGG
AGGAAATGAACCGCGTCGTCGCGGGCCGGATGGCACGCTGGCATTTCGCGCCGACAACCTGCGCGAAGGAAAATTTGCTT
CGGGAGGGAATTGATCAGTCGAGTGTGTTTGTTACCGGAAATACCGTTATCGATGCGTTGCTGGATGTCGCCAAACGTTG
CGACGGTGCGTCACCATATAAAGGCGATCGACGATTGATTCTCGTGACGTCGCATCGTCGCGAGAATTTTGGTGAGGCGT
TTCAAAACATATTGCGAGCGATTAAAACAATCGCAGACGAGAACGTCGACATTCAAGTGCTTTATCCCGTTCATCCGAAT
CCAAATGTACGGACGGGCGCGTACGCATCCCTGGGCGATCATCCTCGTATTACACTCTGCGAACCGCTTGACTACCTGCC
ATTCGTCGCCGCGATGAAACAAGCTTATTTGATCCTGACGGACTCGGGAGGCGTGCAAGAGGAGGCACCGGCGCTAGGCA
AACCCGTGCTCGTCTTGCGACGAGAGACGGAGCGCCCTGAGGCGGTCAGGCACGAAGTGGTAAAGCTGATAGGTACGGAC
TACGCGGATATTGTCAGCAATACGCAACGCTTGCTCGATAACCCTGCAGACTATAGGCGTATGGCGCGTGGCGTATCGCC
ATACGGTGATGGCCTGGCTTCCGGACGGATTGCTCGTATTTTGAAGGGATATTTCGACTTATCCAACTGA

Upstream 100 bases:

>100_bases
CCGGCGGCTTATTGTAAGAGGCTGATTCTCAGATAGAATTTATTACTCGGCTACGCTGGCCATATCGTTTAACATTAATA
TACTGACATTGAGAGGCGCC

Downstream 100 bases:

>100_bases
ACGGGGCGGGACATGGCCGTTCCTTTATGAATCGAGTGGAGGCAACAGATCTTAAACGATCGCTGTGCTTTCGCGTTGAC
GGCTCGTTCCGCTTACCTGC

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MRKRKIIVTVGTRPEAVKMAPLIKQLQHEEWADCRVLATAQHRGMLDQVLRLFEIKPDIDLDIMQPNQSLPTLTSRLITK
LDEVLATEEPDVLLAQGDTTTVLTAALACFYRRVPFGHVEAGLRTGDLSNPFPEEMNRVVAGRMARWHFAPTTCAKENLL
REGIDQSSVFVTGNTVIDALLDVAKRCDGASPYKGDRRLILVTSHRRENFGEAFQNILRAIKTIADENVDIQVLYPVHPN
PNVRTGAYASLGDHPRITLCEPLDYLPFVAAMKQAYLILTDSGGVQEEAPALGKPVLVLRRETERPEAVRHEVVKLIGTD
YADIVSNTQRLLDNPADYRRMARGVSPYGDGLASGRIARILKGYFDLSN

Sequences:

>Translated_369_residues
MRKRKIIVTVGTRPEAVKMAPLIKQLQHEEWADCRVLATAQHRGMLDQVLRLFEIKPDIDLDIMQPNQSLPTLTSRLITK
LDEVLATEEPDVLLAQGDTTTVLTAALACFYRRVPFGHVEAGLRTGDLSNPFPEEMNRVVAGRMARWHFAPTTCAKENLL
REGIDQSSVFVTGNTVIDALLDVAKRCDGASPYKGDRRLILVTSHRRENFGEAFQNILRAIKTIADENVDIQVLYPVHPN
PNVRTGAYASLGDHPRITLCEPLDYLPFVAAMKQAYLILTDSGGVQEEAPALGKPVLVLRRETERPEAVRHEVVKLIGTD
YADIVSNTQRLLDNPADYRRMARGVSPYGDGLASGRIARILKGYFDLSN
>Mature_369_residues
MRKRKIIVTVGTRPEAVKMAPLIKQLQHEEWADCRVLATAQHRGMLDQVLRLFEIKPDIDLDIMQPNQSLPTLTSRLITK
LDEVLATEEPDVLLAQGDTTTVLTAALACFYRRVPFGHVEAGLRTGDLSNPFPEEMNRVVAGRMARWHFAPTTCAKENLL
REGIDQSSVFVTGNTVIDALLDVAKRCDGASPYKGDRRLILVTSHRRENFGEAFQNILRAIKTIADENVDIQVLYPVHPN
PNVRTGAYASLGDHPRITLCEPLDYLPFVAAMKQAYLILTDSGGVQEEAPALGKPVLVLRRETERPEAVRHEVVKLIGTD
YADIVSNTQRLLDNPADYRRMARGVSPYGDGLASGRIARILKGYFDLSN

Specific function: Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=370, Percent_Identity=52.4324324324324, Blast_Score=370, Evalue=1e-104,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 41117; Mature: 41117

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKRKIIVTVGTRPEAVKMAPLIKQLQHEEWADCRVLATAQHRGMLDQVLRLFEIKPDID
CCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCEEEEHHHHCCHHHHHHHHHHCCCCCC
LDIMQPNQSLPTLTSRLITKLDEVLATEEPDVLLAQGDTTTVLTAALACFYRRVPFGHVE
EEEECCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCHHH
AGLRTGDLSNPFPEEMNRVVAGRMARWHFAPTTCAKENLLREGIDQSSVFVTGNTVIDAL
CCCCCCCCCCCCHHHHHHHHHHHHHHEECCCHHHHHHHHHHHCCCCCCEEEECHHHHHHH
LDVAKRCDGASPYKGDRRLILVTSHRRENFGEAFQNILRAIKTIADENVDIQVLYPVHPN
HHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCC
PNVRTGAYASLGDHPRITLCEPLDYLPFVAAMKQAYLILTDSGGVQEEAPALGKPVLVLR
CCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHCEEEEEECCCCCCCCCCCCCCCEEEEE
RETERPEAVRHEVVKLIGTDYADIVSNTQRLLDNPADYRRMARGVSPYGDGLASGRIARI
CCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHH
LKGYFDLSN
HHHHHCCCC
>Mature Secondary Structure
MRKRKIIVTVGTRPEAVKMAPLIKQLQHEEWADCRVLATAQHRGMLDQVLRLFEIKPDID
CCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCEEEEHHHHCCHHHHHHHHHHCCCCCC
LDIMQPNQSLPTLTSRLITKLDEVLATEEPDVLLAQGDTTTVLTAALACFYRRVPFGHVE
EEEECCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCHHH
AGLRTGDLSNPFPEEMNRVVAGRMARWHFAPTTCAKENLLREGIDQSSVFVTGNTVIDAL
CCCCCCCCCCCCHHHHHHHHHHHHHHEECCCHHHHHHHHHHHCCCCCCEEEECHHHHHHH
LDVAKRCDGASPYKGDRRLILVTSHRRENFGEAFQNILRAIKTIADENVDIQVLYPVHPN
HHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCC
PNVRTGAYASLGDHPRITLCEPLDYLPFVAAMKQAYLILTDSGGVQEEAPALGKPVLVLR
CCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHCEEEEEECCCCCCCCCCCCCCCEEEEE
RETERPEAVRHEVVKLIGTDYADIVSNTQRLLDNPADYRRMARGVSPYGDGLASGRIARI
CCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHH
LKGYFDLSN
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]