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The map label for this gene is galE [H]

Identifier: 91782062

GI number: 91782062

Start: 770344

End: 771300

Strand: Direct

Name: galE [H]

Synonym: Bxe_A3782

Alternate gene names: 91782062

Gene position: 770344-771300 (Clockwise)

Preceding gene: 91782061

Following gene: 91782063

Centisome position: 15.73

GC content: 63.32

Gene sequence:

>957_bases
ATGAGTCATGTGCTCGTCACGGGGGCCAACGGCTTTGTCGGTCATGCGCTATGCCGCGCATTGCTTAACGCTGGACATAC
GGTCACCGGCCTCGTTAGGCGCTCAGGGCAGCTTGAAAGCGATGTGAACGAATGGGTCGATGTCAGCGTGGATTTCGCCG
ACGTCGACGCGACATGGCCCGCCGCGCTGCAAGTGGACTGTGTCGTGCACCTAGCGGCGCGAGTCCACGTGATGCGCGAA
GAGTCTGCCGATCCCGACGCGGCGTTTCGCGCGACCAACGTTGATGGCGCGCTTCGCGTTGCCCAGGCCGCACGGCGTCA
TGGCGTGAGGCGTTTTGTCTTTGTCAGCAGCGTTAAGGCGCTGGCCGAAGGCGATTCGGGCCGTCCGGTGTGCGAAGACG
ATCCACCGATGCCACAGGACGCATATGGGCGCTCGAAGCTAGCCGCCGAACAGGCGTTGTGCAGCTACGGCGAAGAGTCC
GGCTTGGACGTCGTGATTGTGCGGCCGCCACTCGTGTATGGGCCACAGGTACGCGCCAATTTCTTGCGATTGATGGACGC
GGTCTGGAAGGGGATGCCGTTGCCGCTAGCTTCGATCGACGCGCGGCGCAGCCTGATCTATGTCGGGAACCTTGCAGACG
CCCTGATGCATTGCGCGGTAGATCCGCGCGCAGCGTACCAGTGCTTCCATGTTGCAGACGCCGCTGCTCCGACGGTCGCC
GAGCTGGCCCGGTCGCTCGCTGGGTATCTGCAAAAGACCTCACGGTTGCTGCCAGTACCGCTGGGCTTGTTGCATATCGC
GGGTCGGCTGACAGGCCGCTCGGCGCACGTGGACCGCCTTGTGTGCTCCCTCCAGCTCGACACCACGCGTATACGCACAA
TGCTCAGCTGGCAACCGCCATATTCCACCGACGAGGGGCTGGCCGAAACCGCCCGTTGGTATCGATCCACGCATTGA

Upstream 100 bases:

>100_bases
TGCATCACGGCGGCGGGGCGGTGCGCAAAGGCTCCGCGCACATTCGCATGTTCATGGCGTCGGCGTATAAATTCTTCAAC
CGGTTTGGCTGGAAGTGGCT

Downstream 100 bases:

>100_bases
GGGAGCGCATGCTGATGCACCTTTCGACCTTCCCAACGTGGGTTGCCGTAACCTTGATCGCGCTTGGCGCTGCCTGCGCA
TGCGCCGCCATTCTGTGGAC

Product: putative epimerase/dehydratase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MSHVLVTGANGFVGHALCRALLNAGHTVTGLVRRSGQLESDVNEWVDVSVDFADVDATWPAALQVDCVVHLAARVHVMRE
ESADPDAAFRATNVDGALRVAQAARRHGVRRFVFVSSVKALAEGDSGRPVCEDDPPMPQDAYGRSKLAAEQALCSYGEES
GLDVVIVRPPLVYGPQVRANFLRLMDAVWKGMPLPLASIDARRSLIYVGNLADALMHCAVDPRAAYQCFHVADAAAPTVA
ELARSLAGYLQKTSRLLPVPLGLLHIAGRLTGRSAHVDRLVCSLQLDTTRIRTMLSWQPPYSTDEGLAETARWYRSTH

Sequences:

>Translated_318_residues
MSHVLVTGANGFVGHALCRALLNAGHTVTGLVRRSGQLESDVNEWVDVSVDFADVDATWPAALQVDCVVHLAARVHVMRE
ESADPDAAFRATNVDGALRVAQAARRHGVRRFVFVSSVKALAEGDSGRPVCEDDPPMPQDAYGRSKLAAEQALCSYGEES
GLDVVIVRPPLVYGPQVRANFLRLMDAVWKGMPLPLASIDARRSLIYVGNLADALMHCAVDPRAAYQCFHVADAAAPTVA
ELARSLAGYLQKTSRLLPVPLGLLHIAGRLTGRSAHVDRLVCSLQLDTTRIRTMLSWQPPYSTDEGLAETARWYRSTH
>Mature_317_residues
SHVLVTGANGFVGHALCRALLNAGHTVTGLVRRSGQLESDVNEWVDVSVDFADVDATWPAALQVDCVVHLAARVHVMREE
SADPDAAFRATNVDGALRVAQAARRHGVRRFVFVSSVKALAEGDSGRPVCEDDPPMPQDAYGRSKLAAEQALCSYGEESG
LDVVIVRPPLVYGPQVRANFLRLMDAVWKGMPLPLASIDARRSLIYVGNLADALMHCAVDPRAAYQCFHVADAAAPTVAE
LARSLAGYLQKTSRLLPVPLGLLHIAGRLTGRSAHVDRLVCSLQLDTTRIRTMLSWQPPYSTDEGLAETARWYRSTH

Specific function: INVOLVED IN THE SYNTHESIS OF ENTEROBACTERIAL COMMON ANTIGEN (ECA) AND REQUIRED FOR SYNTHESIS OF LIPOPOLYSACCHARIDE O-SIDE CHAINS. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI310132178, Length=307, Percent_Identity=27.0358306188925, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI310113012, Length=307, Percent_Identity=27.0358306188925, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI239745448, Length=307, Percent_Identity=27.0358306188925, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI48994969, Length=342, Percent_Identity=26.0233918128655, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI87081792, Length=338, Percent_Identity=24.5562130177515, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 34497; Mature: 34366

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: PS00589 PTS_HPR_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHVLVTGANGFVGHALCRALLNAGHTVTGLVRRSGQLESDVNEWVDVSVDFADVDATWP
CCCEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHCCEEEEECCCCCCC
AALQVDCVVHLAARVHVMREESADPDAAFRATNVDGALRVAQAARRHGVRRFVFVSSVKA
CHHHHHHHHHHHHHHHHHHHCCCCCCHHEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHH
LAEGDSGRPVCEDDPPMPQDAYGRSKLAAEQALCSYGEESGLDVVIVRPPLVYGPQVRAN
HHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHH
FLRLMDAVWKGMPLPLASIDARRSLIYVGNLADALMHCAVDPRAAYQCFHVADAAAPTVA
HHHHHHHHHCCCCCCHHHHHCCCCEEEECCHHHHHHHHCCCHHHHHHHHHHHHHCCCHHH
ELARSLAGYLQKTSRLLPVPLGLLHIAGRLTGRSAHVDRLVCSLQLDTTRIRTMLSWQPP
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHEEECHHHHHHHHCCCCC
YSTDEGLAETARWYRSTH
CCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
SHVLVTGANGFVGHALCRALLNAGHTVTGLVRRSGQLESDVNEWVDVSVDFADVDATWP
CCEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHCCEEEEECCCCCCC
AALQVDCVVHLAARVHVMREESADPDAAFRATNVDGALRVAQAARRHGVRRFVFVSSVKA
CHHHHHHHHHHHHHHHHHHHCCCCCCHHEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHH
LAEGDSGRPVCEDDPPMPQDAYGRSKLAAEQALCSYGEESGLDVVIVRPPLVYGPQVRAN
HHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHH
FLRLMDAVWKGMPLPLASIDARRSLIYVGNLADALMHCAVDPRAAYQCFHVADAAAPTVA
HHHHHHHHHCCCCCCHHHHHCCCCEEEECCHHHHHHHHCCCHHHHHHHHHHHHHCCCHHH
ELARSLAGYLQKTSRLLPVPLGLLHIAGRLTGRSAHVDRLVCSLQLDTTRIRTMLSWQPP
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHEEECHHHHHHHHCCCCC
YSTDEGLAETARWYRSTH
CCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8820651; 10521656 [H]