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The map label for this gene is dprE1 [H]

Identifier: 91782059

GI number: 91782059

Start: 766411

End: 767727

Strand: Reverse

Name: dprE1 [H]

Synonym: Bxe_A3785

Alternate gene names: 91782059

Gene position: 767727-766411 (Counterclockwise)

Preceding gene: 91782060

Following gene: 91782058

Centisome position: 15.68

GC content: 60.74

Gene sequence:

>1317_bases
ATGAGTACTGTACTGTCCTGGGGACGTTACCCACATCTGCCGCAGGAAGTCCACGGCGTTGCATGGCGTGACTCCGCACA
AGCCGCGTGGCTGGACGCGAGCCGCGAAAGCGGAACCACCCTCGCGTTCGGCAATGGCCGCAGTTATGGCGACAGTTGTC
TCGCCGCCTCGGGCCATGTCGTGCAGACTCTAGCGCTCGACCGCCTGATTGCAGCGGACTGGCAAACCGGCGTGCTGCGC
GCGGAACCTGGCGTGACACTCGAACAGATTCTCGATGTCGCCATTCCCCGCGGCTGGATGTTGCCGGTGACGCCTGGCAC
CAAATACGCGACTTTGGGCGGCGCTATCGCCAACGATGTCCACGGCAAGAATCATCACGTGCGCGGCACCTTCGGCCGGC
ACGTGCGCCGCTTTGCGCTCGCGCGCAGTGACGGCACGCAGTTTGAATGCTCACCCGACGAACAGCCTGAATTCTTCGCC
GCAACAATTGGTGGACTCGGTCTCACCGGTTTGATCCTGTGGGCGGAGATTCAATTGATGCCGATCCGCTCGAGCATGAT
CGCCATGAAGAGCATTCGCTTCACCAATCTCGACGAGTTCTTCGCACTATCCGAACGGCTCGACCCCCTGCACGAATACA
GCGTTGCATGGGTTGATTGCCAAAGCCGCGGCTCGGCGCTCGGGCGCGGCATCTTCATGGTGGGCGACCATGCAACGGAG
GGCCCGCTCGAAGTTGAACGCCGCACGAAGCGCATCGTCCCGTTTACGCTGCCGATTCCAGTGTTCAACCGCGTTACATT
ACGTGCACTCAACGAGCTCTACTATCAGAAGCAACAAAGCGGCGAAGTCAGCGCAACGGTCAGTTACGACACCTACTTCT
ACCCGCTGGACAGCTTGCTGGAATGGAACCGCATCTATGGCCGCGCGGGCTTTCAGCAGTATCAGTGCGTGGTGCCGCCG
AGCTCGGCACGTGAAGCAACGCGCGAGATTCTCGACGCCATTTCCGAAAGCGGCACCGGCTCGTTTCTCGCGGTGATGAA
ACGCTGCGGCGATTTGCGTTCGCCCGGTTTGTTATCCTTTCCGCGCGAAGGCACATCGCTCGCACTTGATTTCCCCCAGC
GCGATGCGTTGAATACACGACTTTTCGCCAGACTCGATGCGATCGTGAGCGAAGCGGGTGGTCGCATCTACCCGGCCAAG
GACGCGCACATGTCTGGCGCCGACTTTCGCACCGCCTACCCTCAATGGCATCAACTCGAAGCGCTGCGCGACCCTGCCCT
GCTTTCGCGCTTCTGGGAACGGACTACTCGAACATGA

Upstream 100 bases:

>100_bases
TCTGATGCACGACGACCCGATCGTTTTCGCGGCGCGCGATCGTGTCAGCCTCGCTGTCGTCGTGCTGTGCGGCCTGGTTT
TCTGGGCGGCCATCTAATCG

Downstream 100 bases:

>100_bases
AAAACATTCTTATCGTCGGCGCTACGTCGGCGATTGCCATTGCTTGTGCCCGCAAATGGGCTTCAGAAGGCGCACGCTTT
TTTCTGGTGGCTCGCAATGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 437

Protein sequence:

>438_residues
MSTVLSWGRYPHLPQEVHGVAWRDSAQAAWLDASRESGTTLAFGNGRSYGDSCLAASGHVVQTLALDRLIAADWQTGVLR
AEPGVTLEQILDVAIPRGWMLPVTPGTKYATLGGAIANDVHGKNHHVRGTFGRHVRRFALARSDGTQFECSPDEQPEFFA
ATIGGLGLTGLILWAEIQLMPIRSSMIAMKSIRFTNLDEFFALSERLDPLHEYSVAWVDCQSRGSALGRGIFMVGDHATE
GPLEVERRTKRIVPFTLPIPVFNRVTLRALNELYYQKQQSGEVSATVSYDTYFYPLDSLLEWNRIYGRAGFQQYQCVVPP
SSAREATREILDAISESGTGSFLAVMKRCGDLRSPGLLSFPREGTSLALDFPQRDALNTRLFARLDAIVSEAGGRIYPAK
DAHMSGADFRTAYPQWHQLEALRDPALLSRFWERTTRT

Sequences:

>Translated_438_residues
MSTVLSWGRYPHLPQEVHGVAWRDSAQAAWLDASRESGTTLAFGNGRSYGDSCLAASGHVVQTLALDRLIAADWQTGVLR
AEPGVTLEQILDVAIPRGWMLPVTPGTKYATLGGAIANDVHGKNHHVRGTFGRHVRRFALARSDGTQFECSPDEQPEFFA
ATIGGLGLTGLILWAEIQLMPIRSSMIAMKSIRFTNLDEFFALSERLDPLHEYSVAWVDCQSRGSALGRGIFMVGDHATE
GPLEVERRTKRIVPFTLPIPVFNRVTLRALNELYYQKQQSGEVSATVSYDTYFYPLDSLLEWNRIYGRAGFQQYQCVVPP
SSAREATREILDAISESGTGSFLAVMKRCGDLRSPGLLSFPREGTSLALDFPQRDALNTRLFARLDAIVSEAGGRIYPAK
DAHMSGADFRTAYPQWHQLEALRDPALLSRFWERTTRT
>Mature_437_residues
STVLSWGRYPHLPQEVHGVAWRDSAQAAWLDASRESGTTLAFGNGRSYGDSCLAASGHVVQTLALDRLIAADWQTGVLRA
EPGVTLEQILDVAIPRGWMLPVTPGTKYATLGGAIANDVHGKNHHVRGTFGRHVRRFALARSDGTQFECSPDEQPEFFAA
TIGGLGLTGLILWAEIQLMPIRSSMIAMKSIRFTNLDEFFALSERLDPLHEYSVAWVDCQSRGSALGRGIFMVGDHATEG
PLEVERRTKRIVPFTLPIPVFNRVTLRALNELYYQKQQSGEVSATVSYDTYFYPLDSLLEWNRIYGRAGFQQYQCVVPPS
SAREATREILDAISESGTGSFLAVMKRCGDLRSPGLLSFPREGTSLALDFPQRDALNTRLFARLDAIVSEAGGRIYPAKD
AHMSGADFRTAYPQWHQLEALRDPALLSRFWERTTRT

Specific function: Involved in the epimerization of decaprenylphosphoryl ribose (DPR) to decaprenylphosphoryl arabinose (DPA) a precursor for arabinan synthesis in mycobacterial cell wall biosynthesis. Probably catalyzes the oxidation at C-2 of decaprenylphosphoryl ribose (

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007173
- InterPro:   IPR016166
- InterPro:   IPR016168
- InterPro:   IPR006094 [H]

Pfam domain/function: PF04030 ALO; PF01565 FAD_binding_4 [H]

EC number: NA

Molecular weight: Translated: 48627; Mature: 48495

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTVLSWGRYPHLPQEVHGVAWRDSAQAAWLDASRESGTTLAFGNGRSYGDSCLAASGHV
CCCCCCCCCCCCCCHHHCCCEECCCCCEEEEECCCCCCCEEEECCCCCCCCHHHHCCCHH
VQTLALDRLIAADWQTGVLRAEPGVTLEQILDVAIPRGWMLPVTPGTKYATLGGAIANDV
HHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHCCCCCEEECCCCCCEEECCCHHHHCC
HGKNHHVRGTFGRHVRRFALARSDGTQFECSPDEQPEFFAATIGGLGLTGLILWAEIQLM
CCCCCEECCHHHHHHHHHHHHCCCCCEEECCCCCCCCEEHHHHCCCHHHHHHEEHEEEEE
PIRSSMIAMKSIRFTNLDEFFALSERLDPLHEYSVAWVDCQSRGSALGRGIFMVGDHATE
ECHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHCCEEEEECCCCCCHHCCCEEEECCCCCC
GPLEVERRTKRIVPFTLPIPVFNRVTLRALNELYYQKQQSGEVSATVSYDTYFYPLDSLL
CCHHHHHHHCEECEEEECCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECEEECCHHHHH
EWNRIYGRAGFQQYQCVVPPSSAREATREILDAISESGTGSFLAVMKRCGDLRSPGLLSF
HHHHHHCCCCCCCCEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCC
PREGTSLALDFPQRDALNTRLFARLDAIVSEAGGRIYPAKDAHMSGADFRTAYPQWHQLE
CCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCHHHHH
ALRDPALLSRFWERTTRT
HHCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
STVLSWGRYPHLPQEVHGVAWRDSAQAAWLDASRESGTTLAFGNGRSYGDSCLAASGHV
CCCCCCCCCCCCCHHHCCCEECCCCCEEEEECCCCCCCEEEECCCCCCCCHHHHCCCHH
VQTLALDRLIAADWQTGVLRAEPGVTLEQILDVAIPRGWMLPVTPGTKYATLGGAIANDV
HHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHCCCCCEEECCCCCCEEECCCHHHHCC
HGKNHHVRGTFGRHVRRFALARSDGTQFECSPDEQPEFFAATIGGLGLTGLILWAEIQLM
CCCCCEECCHHHHHHHHHHHHCCCCCEEECCCCCCCCEEHHHHCCCHHHHHHEEHEEEEE
PIRSSMIAMKSIRFTNLDEFFALSERLDPLHEYSVAWVDCQSRGSALGRGIFMVGDHATE
ECHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHCCEEEEECCCCCCHHCCCEEEECCCCCC
GPLEVERRTKRIVPFTLPIPVFNRVTLRALNELYYQKQQSGEVSATVSYDTYFYPLDSLL
CCHHHHHHHCEECEEEECCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECEEECCHHHHH
EWNRIYGRAGFQQYQCVVPPSSAREATREILDAISESGTGSFLAVMKRCGDLRSPGLLSF
HHHHHHCCCCCCCCEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCC
PREGTSLALDFPQRDALNTRLFARLDAIVSEAGGRIYPAKDAHMSGADFRTAYPQWHQLE
CCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCHHHHH
ALRDPALLSRFWERTTRT
HHCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]