Click here to switch to the map view.

The map label for this gene is rmlA1 [H]

Identifier: 91782043

GI number: 91782043

Start: 743984

End: 744862

Strand: Direct

Name: rmlA1 [H]

Synonym: Bxe_A3801

Alternate gene names: 91782043

Gene position: 743984-744862 (Clockwise)

Preceding gene: 91782042

Following gene: 91782044

Centisome position: 15.2

GC content: 56.54

Gene sequence:

>879_bases
ATGCGTAAAGGCATTATCCTAGCCGGTGGGTCCGGCACGCGTCTTTACCCGATCACGCGGTCGGTGTCGAAGCAACTGCT
ACCCGTCTACGACAAGCCGATGATCTACTATCCGCTGTCGACGCTGATGCTGGCGGGTATTCGCGACATCCTTGTGATCT
CCACGGCGGAAGATACGCCGCGTTTTGCAGAGATGCTCGGCGACGGCAGCGCTTGGGGCATCGATCTGCAATACGCCGTG
CAGCCTTCGCCCGATGGACTTGCGCAGGCCTTTATTATCGGCCGTGAATTCATCGGCTCTGATCCTTGCACGTTGATTCT
CGGCGACAACATTTTCCACGGGCATGATCTCGTGCGTCAGCTGACACGTGCGGGGCAGTCCGAGCAGGGCGCGACTGTAT
TCGCCTATCACGTGCACGATCCGGAGCGTTATGGGGTAGTTGAGTTCGACGAGAATTTCCACGCGCTATCGCTGGAAGAA
AAGCCGCTCAAGCCGCGCTCCAATTATGCGGTGACTGGTCTTTATTTCTACGACAACCAGGTCTGCGACATTGCAGCTGA
CGTCAAGCCGTCAGCACGTGGCGAGCTCGAAATCACGGATGTCAACAAACGATATCTGGAAATAGCTCAGCTCGACGTTG
AGATCATGGGGCGTGGATATGCGTGGCTGGATACAGGCACGCACGATTCGCTGCTTGAGGCCGCCAGTTTCATAGCGACG
CTGCAGAGTCGGCAGGGGCTGATGGTGGCCTGCCCGGAAGAGATTGCGTACCGCAGCCATTGGATCAGTGCCGAACAGGT
CGAACGCCTCGCTGGACCGCTTGCCAAAAATCGATACGGCCAATACCTGAAACAGATCATTTCGGAAGCAGTTAAATGA

Upstream 100 bases:

>100_bases
CGATACGCACAAGCTGCGCCAAACCTTCGGTATCAATCTCCCCGATTGGCGCGACGGTGTGCACCACCTGCTAGAACAGA
TTCTTCCGTGAGTAAAAAAC

Downstream 100 bases:

>100_bases
GCATGACCGTCATCGCAACCGAGATCCCGGACGTATTGATCCTCGAACCCAAGGTGTTCGGAGATGATCGCGGCTTCTTT
TATGAAAGCTTTAATGCTCG

Product: glucose-1-phosphate thymidylyltransferase

Products: NA

Alternate protein names: G1P-TT 1; dTDP-glucose pyrophosphorylase 1; dTDP-glucose synthase 1 [H]

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MRKGIILAGGSGTRLYPITRSVSKQLLPVYDKPMIYYPLSTLMLAGIRDILVISTAEDTPRFAEMLGDGSAWGIDLQYAV
QPSPDGLAQAFIIGREFIGSDPCTLILGDNIFHGHDLVRQLTRAGQSEQGATVFAYHVHDPERYGVVEFDENFHALSLEE
KPLKPRSNYAVTGLYFYDNQVCDIAADVKPSARGELEITDVNKRYLEIAQLDVEIMGRGYAWLDTGTHDSLLEAASFIAT
LQSRQGLMVACPEEIAYRSHWISAEQVERLAGPLAKNRYGQYLKQIISEAVK

Sequences:

>Translated_292_residues
MRKGIILAGGSGTRLYPITRSVSKQLLPVYDKPMIYYPLSTLMLAGIRDILVISTAEDTPRFAEMLGDGSAWGIDLQYAV
QPSPDGLAQAFIIGREFIGSDPCTLILGDNIFHGHDLVRQLTRAGQSEQGATVFAYHVHDPERYGVVEFDENFHALSLEE
KPLKPRSNYAVTGLYFYDNQVCDIAADVKPSARGELEITDVNKRYLEIAQLDVEIMGRGYAWLDTGTHDSLLEAASFIAT
LQSRQGLMVACPEEIAYRSHWISAEQVERLAGPLAKNRYGQYLKQIISEAVK
>Mature_292_residues
MRKGIILAGGSGTRLYPITRSVSKQLLPVYDKPMIYYPLSTLMLAGIRDILVISTAEDTPRFAEMLGDGSAWGIDLQYAV
QPSPDGLAQAFIIGREFIGSDPCTLILGDNIFHGHDLVRQLTRAGQSEQGATVFAYHVHDPERYGVVEFDENFHALSLEE
KPLKPRSNYAVTGLYFYDNQVCDIAADVKPSARGELEITDVNKRYLEIAQLDVEIMGRGYAWLDTGTHDSLLEAASFIAT
LQSRQGLMVACPEEIAYRSHWISAEQVERLAGPLAKNRYGQYLKQIISEAVK

Specific function: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis [H]

COG id: COG1209

COG function: function code M; dTDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucose-1-phosphate thymidylyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1788351, Length=290, Percent_Identity=72.4137931034483, Blast_Score=452, Evalue=1e-128,
Organism=Escherichia coli, GI1790224, Length=285, Percent_Identity=64.2105263157895, Blast_Score=390, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI133931050, Length=242, Percent_Identity=23.5537190082645, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320148, Length=248, Percent_Identity=25.8064516129032, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21355443, Length=248, Percent_Identity=27.4193548387097, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24644084, Length=248, Percent_Identity=27.4193548387097, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005907
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.24 [H]

Molecular weight: Translated: 32445; Mature: 32445

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKGIILAGGSGTRLYPITRSVSKQLLPVYDKPMIYYPLSTLMLAGIRDILVISTAEDTP
CCCCEEEECCCCCEEEEEHHHHHHHHCCCCCCCEEEECHHHHHHHCCCEEEEEECCCCCH
RFAEMLGDGSAWGIDLQYAVQPSPDGLAQAFIIGREFIGSDPCTLILGDNIFHGHDLVRQ
HHHHHHCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEECCCEECHHHHHHH
LTRAGQSEQGATVFAYHVHDPERYGVVEFDENFHALSLEEKPLKPRSNYAVTGLYFYDNQ
HHHCCCCCCCCEEEEEEECCCCCCCEEEECCCEEEEECCCCCCCCCCCEEEEEEEEECCC
VCDIAADVKPSARGELEITDVNKRYLEIAQLDVEIMGRGYAWLDTGTHDSLLEAASFIAT
EEEEEECCCCCCCCCEEEEECCHHHHHHHHHCEEEECCCEEEEECCCCHHHHHHHHHHHH
LQSRQGLMVACPEEIAYRSHWISAEQVERLAGPLAKNRYGQYLKQIISEAVK
HHHCCCEEEECCHHHHHHHHCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRKGIILAGGSGTRLYPITRSVSKQLLPVYDKPMIYYPLSTLMLAGIRDILVISTAEDTP
CCCCEEEECCCCCEEEEEHHHHHHHHCCCCCCCEEEECHHHHHHHCCCEEEEEECCCCCH
RFAEMLGDGSAWGIDLQYAVQPSPDGLAQAFIIGREFIGSDPCTLILGDNIFHGHDLVRQ
HHHHHHCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEECCCEECHHHHHHH
LTRAGQSEQGATVFAYHVHDPERYGVVEFDENFHALSLEEKPLKPRSNYAVTGLYFYDNQ
HHHCCCCCCCCEEEEEEECCCCCCCEEEECCCEEEEECCCCCCCCCCCEEEEEEEEECCC
VCDIAADVKPSARGELEITDVNKRYLEIAQLDVEIMGRGYAWLDTGTHDSLLEAASFIAT
EEEEEECCCCCCCCCEEEEECCHHHHHHHHHCEEEECCCEEEEECCCCHHHHHHHHHHHH
LQSRQGLMVACPEEIAYRSHWISAEQVERLAGPLAKNRYGQYLKQIISEAVK
HHHCCCEEEECCHHHHHHHHCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7517391; 9097040; 9278503; 7517390 [H]