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The map label for this gene is pcaR [H]

Identifier: 91781940

GI number: 91781940

Start: 622451

End: 623269

Strand: Direct

Name: pcaR [H]

Synonym: Bxe_A3903

Alternate gene names: 91781940

Gene position: 622451-623269 (Clockwise)

Preceding gene: 91781938

Following gene: 91781942

Centisome position: 12.71

GC content: 65.81

Gene sequence:

>819_bases
ATGTTTTGCAAACACGTCCGAGTGTACCACCCCATGACGCCTGCATCCACTCTCTCTGAACCGCTCGACGAGCGCAAATT
CGTTGTCGCCCTTGCACGCGGGCTGGATTTGCTGCGCGCGTTCAAACCGGGCGAAACCATGCTCGGCAACCGCGATTTCG
TCGAGCGCACGGGCTTGCCGAAGGCCACGGTCAACCGTCTTGCCTACACGCTGACCGTGCTCGGCTATCTGCGGTTGGAC
GAATCCCTGGGTAAATATGCGCTCGACGCCGGCGTGCTGTCGCTCGGATTCGCGCTGCTCTCGGGCACGGACACGCTCGA
ACTGGCACGCCCGCATATGCGCACGTTCGCGCGCGAGGTGGGCGCGGCGGTCTCGCTCGGTTGCCGCGACGGGCTCGACA
TGATCTATCTGGAGACGATCCGCAGTGAAACCGCGCTGACGCTCGGGCTGGCATCGGGTTCCAGACTGTCGATGCTGACC
AGTTCGATGGGGCGCGCCTATCTCGCCGTGCAACCGCTCGACGTGCGCGCCGCGTTGCTGGCGGAACTGCGCAAGGCGGC
GGGCAACGAAGGCGACGCGCTGGTCGCCGACGCGGAGAAAGAGATCGCCGCGTTCGCCGCGCAGCGCTGCTGCTATTCGT
TCCGGGCGTGGCACGACGACGTCAATGCGGTCGCGGTGCCGTTTCGCGAGCCGCGTGAAGGTCGCTGGCTGGTGCTGAGT
TGCAGCGGGCCGGCTTCATCGATGGGCGAAGAGGTGTTCCGTGACAACGTCGCGCCGCGGCTGATGGCGCTTGCGCGGCG
GTTAGGCGATACGGGCTGA

Upstream 100 bases:

>100_bases
CTTCCCAGTGAAACTGCGCGGCCTCGGCCATGACTTATCTCCTGATTTCTTGCTTGACGAAACGTGCGTGAGCTTGACTT
AAGTTCCGCTATGCGAAACA

Downstream 100 bases:

>100_bases
AGCGGCGGCGGCGCGAGCGGCCGCTTCGCCGGGCTCAATCCACGTGCCTCAAACCGCCCGGTCGTGATAATGCGCGTTGA
ACAGCGGCCCTTGCACGAAG

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MFCKHVRVYHPMTPASTLSEPLDERKFVVALARGLDLLRAFKPGETMLGNRDFVERTGLPKATVNRLAYTLTVLGYLRLD
ESLGKYALDAGVLSLGFALLSGTDTLELARPHMRTFAREVGAAVSLGCRDGLDMIYLETIRSETALTLGLASGSRLSMLT
SSMGRAYLAVQPLDVRAALLAELRKAAGNEGDALVADAEKEIAAFAAQRCCYSFRAWHDDVNAVAVPFREPREGRWLVLS
CSGPASSMGEEVFRDNVAPRLMALARRLGDTG

Sequences:

>Translated_272_residues
MFCKHVRVYHPMTPASTLSEPLDERKFVVALARGLDLLRAFKPGETMLGNRDFVERTGLPKATVNRLAYTLTVLGYLRLD
ESLGKYALDAGVLSLGFALLSGTDTLELARPHMRTFAREVGAAVSLGCRDGLDMIYLETIRSETALTLGLASGSRLSMLT
SSMGRAYLAVQPLDVRAALLAELRKAAGNEGDALVADAEKEIAAFAAQRCCYSFRAWHDDVNAVAVPFREPREGRWLVLS
CSGPASSMGEEVFRDNVAPRLMALARRLGDTG
>Mature_272_residues
MFCKHVRVYHPMTPASTLSEPLDERKFVVALARGLDLLRAFKPGETMLGNRDFVERTGLPKATVNRLAYTLTVLGYLRLD
ESLGKYALDAGVLSLGFALLSGTDTLELARPHMRTFAREVGAAVSLGCRDGLDMIYLETIRSETALTLGLASGSRLSMLT
SSMGRAYLAVQPLDVRAALLAELRKAAGNEGDALVADAEKEIAAFAAQRCCYSFRAWHDDVNAVAVPFREPREGRWLVLS
CSGPASSMGEEVFRDNVAPRLMALARRLGDTG

Specific function: Positive regulator of all genes within the pca regulon, pcaBDC, pcaIJ and pcaF. Also required for the chemotactic response to aromatic compounds [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI87082359, Length=144, Percent_Identity=27.0833333333333, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012794
- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 29585; Mature: 29585

Theoretical pI: Translated: 7.87; Mature: 7.87

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFCKHVRVYHPMTPASTLSEPLDERKFVVALARGLDLLRAFKPGETMLGNRDFVERTGLP
CCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCHHHHHCCCC
KATVNRLAYTLTVLGYLRLDESLGKYALDAGVLSLGFALLSGTDTLELARPHMRTFAREV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
GAAVSLGCRDGLDMIYLETIRSETALTLGLASGSRLSMLTSSMGRAYLAVQPLDVRAALL
HHHHCCCCCCCCHHHHHHHHHCCCEEEEEECCCCHHHHHHHHCCCEEEEECCHHHHHHHH
AELRKAAGNEGDALVADAEKEIAAFAAQRCCYSFRAWHDDVNAVAVPFREPREGRWLVLS
HHHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCEEEEE
CSGPASSMGEEVFRDNVAPRLMALARRLGDTG
CCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MFCKHVRVYHPMTPASTLSEPLDERKFVVALARGLDLLRAFKPGETMLGNRDFVERTGLP
CCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCHHHHHCCCC
KATVNRLAYTLTVLGYLRLDESLGKYALDAGVLSLGFALLSGTDTLELARPHMRTFAREV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
GAAVSLGCRDGLDMIYLETIRSETALTLGLASGSRLSMLTSSMGRAYLAVQPLDVRAALL
HHHHCCCCCCCCHHHHHHHHHCCCEEEEEECCCCHHHHHHHHCCCEEEEECCHHHHHHHH
AELRKAAGNEGDALVADAEKEIAAFAAQRCCYSFRAWHDDVNAVAVPFREPREGRWLVLS
HHHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCEEEEE
CSGPASSMGEEVFRDNVAPRLMALARRLGDTG
CCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8083169 [H]