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The map label for this gene is degS [H]

Identifier: 91781919

GI number: 91781919

Start: 605011

End: 606102

Strand: Reverse

Name: degS [H]

Synonym: Bxe_A3924

Alternate gene names: 91781919

Gene position: 606102-605011 (Counterclockwise)

Preceding gene: 91781921

Following gene: 91781917

Centisome position: 12.38

GC content: 62.27

Gene sequence:

>1092_bases
ATGCGCGAAGCTCCCATTCACACCGAGGAGAGCTTCCGCCTGCTAGTCGAAGCAATCGACGACTACGCAATCTTCATGCT
GGACGCATCAGGCAACGTCGTGAACTGGAACACCGGCGCACGGAAGATGAAAGGGTATGAGGTCGATGAAATCATCGGCC
GCCACTTCTCGGTCTTTTACACGCCCGAGGACGTTGCAGCAGGCCAGCCCGGTCTTCTGCTCGCGGCAGCGGTCGCGCAA
GGCAGAGTGGTGAGCGAGGGCTGGCGCGTTCGCAAGGACGGTTCGAAATTCTGGGCGAACGTTGTCATCACAACCGTCCG
CACCCCTACCGGCGAGCTCCGCGGTTTTGCAAAGGTGACGCAGGACCTGACCGAACGAAAACGGCTGGAAGAATTCGAAC
AACTCAGAGCGTTAGCCGCGCACATTCAGGCCGCTCGCGAGGAAGAGCAGATCCGCATCGCCCGCGAACTTCACGATGAC
ATAGGCCAGCAACTCACCGCGCTCAAGATGGCGCTTGCGGGTCTCGACAGCATCGTTCGCGACCAGGAGGCAGGCGCCGC
ACGCACCGCGCCTCACATTGCGGACATGCATCAACTGATCGACGCGACGGTCGCCTCGCTACGGCGAATCGCAGCCGGAT
TGCGTCCCGTCATGCTGGAGACGCTGGGGCTCATCCCGACACTCGAATGGCTCATCGACGATTTCATGCAGCGGTACGAC
ATTGCCGTCGAGGCACGGATCGAGGCCGATGACATGAAGCTGAGCGAAGCGGCTGACGAAGGCCTGTTCCATATCGTGCA
GGAAGCACTGACCAACGTGGCCCGGCATGCGCACGCCGACCGGGTGACGATCGATCTGGCGCGCGACGGCCGCACCTGTG
TATTGCGCGTTACGGACGACGGGCAGGGAATGACGCCGGCGGCGCCTTCGCGCCCGACCTCTTTCGGCCTGCTGGGCATG
CGTGAGCGAGTTCATCACCTGAATGGCACGATGTCGATCGACAGCGCGCCCGGCCGCGGTTTTCGTCTTACCCTCATCTT
TCCACTGGACGCCGTCGAGCGAAAGCCCTCGAGCCCGGAAGGAGCCGCGTAA

Upstream 100 bases:

>100_bases
ACAGGTCGGGGGCTCAACCTTTTCGGTTCGTGCCAATCGGGCTCTCGGGTCGGAGAAAACGATGACGGGTAAGGCAGATG
CTGGACCGCGGGGTAACACA

Downstream 100 bases:

>100_bases
TTCCGCATTCCGCCTCTCAGAAAAGAACGGCGTCCGAATCCTGGCAAATTCAGGCGGACAGAATGCCGATCCCATGCGAC
GGCGCCGCCTATCCCATCCG

Product: PAS/PAC sensor Signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MREAPIHTEESFRLLVEAIDDYAIFMLDASGNVVNWNTGARKMKGYEVDEIIGRHFSVFYTPEDVAAGQPGLLLAAAVAQ
GRVVSEGWRVRKDGSKFWANVVITTVRTPTGELRGFAKVTQDLTERKRLEEFEQLRALAAHIQAAREEEQIRIARELHDD
IGQQLTALKMALAGLDSIVRDQEAGAARTAPHIADMHQLIDATVASLRRIAAGLRPVMLETLGLIPTLEWLIDDFMQRYD
IAVEARIEADDMKLSEAADEGLFHIVQEALTNVARHAHADRVTIDLARDGRTCVLRVTDDGQGMTPAAPSRPTSFGLLGM
RERVHHLNGTMSIDSAPGRGFRLTLIFPLDAVERKPSSPEGAA

Sequences:

>Translated_363_residues
MREAPIHTEESFRLLVEAIDDYAIFMLDASGNVVNWNTGARKMKGYEVDEIIGRHFSVFYTPEDVAAGQPGLLLAAAVAQ
GRVVSEGWRVRKDGSKFWANVVITTVRTPTGELRGFAKVTQDLTERKRLEEFEQLRALAAHIQAAREEEQIRIARELHDD
IGQQLTALKMALAGLDSIVRDQEAGAARTAPHIADMHQLIDATVASLRRIAAGLRPVMLETLGLIPTLEWLIDDFMQRYD
IAVEARIEADDMKLSEAADEGLFHIVQEALTNVARHAHADRVTIDLARDGRTCVLRVTDDGQGMTPAAPSRPTSFGLLGM
RERVHHLNGTMSIDSAPGRGFRLTLIFPLDAVERKPSSPEGAA
>Mature_363_residues
MREAPIHTEESFRLLVEAIDDYAIFMLDASGNVVNWNTGARKMKGYEVDEIIGRHFSVFYTPEDVAAGQPGLLLAAAVAQ
GRVVSEGWRVRKDGSKFWANVVITTVRTPTGELRGFAKVTQDLTERKRLEEFEQLRALAAHIQAAREEEQIRIARELHDD
IGQQLTALKMALAGLDSIVRDQEAGAARTAPHIADMHQLIDATVASLRRIAAGLRPVMLETLGLIPTLEWLIDDFMQRYD
IAVEARIEADDMKLSEAADEGLFHIVQEALTNVARHAHADRVTIDLARDGRTCVLRVTDDGQGMTPAAPSRPTSFGLLGM
RERVHHLNGTMSIDSAPGRGFRLTLIFPLDAVERKPSSPEGAA

Specific function: Member of the two-component regulatory system degS/degU. Involved in a sensory transduction pathway that affect the production of enzymes that degrade polymeric carbon and nitrogen sources. DegS probably acts as a kinase that phosphorylates degU [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI87082311, Length=208, Percent_Identity=31.7307692307692, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787474, Length=200, Percent_Identity=26.5, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788812, Length=203, Percent_Identity=27.5862068965517, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR008595
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR016381 [H]

Pfam domain/function: PF05384 DegS; PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 40058; Mature: 40058

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREAPIHTEESFRLLVEAIDDYAIFMLDASGNVVNWNTGARKMKGYEVDEIIGRHFSVFY
CCCCCCCCHHHHHHHHHHHCCEEEEEEECCCCEEECCCCCHHCCCCCHHHHHCCCEEEEE
TPEDVAAGQPGLLLAAAVAQGRVVSEGWRVRKDGSKFWANVVITTVRTPTGELRGFAKVT
CCHHHCCCCCCHHHHHHHHCCCEECCCCEECCCCHHHEEEEEEEEEECCCHHHHHHHHHH
QDLTERKRLEEFEQLRALAAHIQAAREEEQIRIARELHDDIGQQLTALKMALAGLDSIVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DQEAGAARTAPHIADMHQLIDATVASLRRIAAGLRPVMLETLGLIPTLEWLIDDFMQRYD
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHC
IAVEARIEADDMKLSEAADEGLFHIVQEALTNVARHAHADRVTIDLARDGRTCVLRVTDD
EEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEEECC
GQGMTPAAPSRPTSFGLLGMRERVHHLNGTMSIDSAPGRGFRLTLIFPLDAVERKPSSPE
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEECCCCCCCEEEEEEECCHHHHCCCCCCC
GAA
CCC
>Mature Secondary Structure
MREAPIHTEESFRLLVEAIDDYAIFMLDASGNVVNWNTGARKMKGYEVDEIIGRHFSVFY
CCCCCCCCHHHHHHHHHHHCCEEEEEEECCCCEEECCCCCHHCCCCCHHHHHCCCEEEEE
TPEDVAAGQPGLLLAAAVAQGRVVSEGWRVRKDGSKFWANVVITTVRTPTGELRGFAKVT
CCHHHCCCCCCHHHHHHHHCCCEECCCCEECCCCHHHEEEEEEEEEECCCHHHHHHHHHH
QDLTERKRLEEFEQLRALAAHIQAAREEEQIRIARELHDDIGQQLTALKMALAGLDSIVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DQEAGAARTAPHIADMHQLIDATVASLRRIAAGLRPVMLETLGLIPTLEWLIDDFMQRYD
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHC
IAVEARIEADDMKLSEAADEGLFHIVQEALTNVARHAHADRVTIDLARDGRTCVLRVTDD
EEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEEECC
GQGMTPAAPSRPTSFGLLGMRERVHHLNGTMSIDSAPGRGFRLTLIFPLDAVERKPSSPE
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEECCCCCCCEEEEEEECCHHHHCCCCCCC
GAA
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3141378; 3141377; 9384377; 3136143 [H]