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The map label for this gene is glcD [H]

Identifier: 91781867

GI number: 91781867

Start: 541719

End: 543212

Strand: Reverse

Name: glcD [H]

Synonym: Bxe_A3978

Alternate gene names: 91781867

Gene position: 543212-541719 (Counterclockwise)

Preceding gene: 91781868

Following gene: 91781866

Centisome position: 11.1

GC content: 65.8

Gene sequence:

>1494_bases
ATGAACGCACCCGCTGAACTGACCGCCGAGGTACTCGCCCAGCGCCAGCGCGAAGTCGTGCAGGCGCTGATGGCCGTGTT
GCCGACCCACTGTCTGCTGTATCGCGAAGAAGACACCGTCGCCTATGAATGCGACGGTCTCGCCGCCTACCGGCGTCTGC
CGCTCGCGGTCGCGTTGCCGGAGACGGAATCGCAGGTGCAGCGCATCGTGCAGATCTGCCACCGCCTCGACGTGCCGATC
GTCCCGCGCGGTGCGGGCACCGGCCTGTCCGGCGGCGCCATGCCGATCCGCCACGGTGTGGTGGTGTCGCTCGCGCGCTT
GCGCAAGATCGTCGAGGTCGATTCGTACGCGCGAACCGCCACGGTGCAGCCGGGCGTGCGCAACCTGTCCATCTCCGAAG
CCGCCGCACCTTACGGCCTGTATTACGCGCCGGACCCGTCGTCGCAGATTGCCTGCACGATCGGCGGCAATGTCTCGGAG
AATTCCGGCGGCGTTCACTGCCTCAAATACGGTCTGACGGTGCATAACGTGCTGCGCGTGCGCGCCGTCACGATGGAAGG
CGAAATCGTCGAGTTCGGCTCGCTCGCGCCGGATGCGCCCGGCCTCGATCTGCTGGCGGTGCTGATCGGCAGCGAAGGCA
TGTTTGCGATCGTCACCGAAGTCACCGTCAAGCTGATCCCCAAGCCGCAAACGGCGCAGGTCATCATGGCCAGTTTCGAC
GACGTCGTGAAAGGCGGCGACGCGGTTGCCGGCATCATTGCGGCGGGCATCATCCCGGCGGGTCTGGAAATGATGGACAA
GCCGGCCACGCGCGCCGTCGAGGAATTCGTCAACGCGGGCTACGATCTCGACGCGGCGGCGATCCTGCTGTGCGAATCGG
ACGGCACGCCCGACGAAGTCGCCGACGAGATCGTGCGCATGACCGCGGTGCTGCGCGAACACGGCGCCACGCGCATCCAG
ATTTCGCGCTCGGAAAACGAACGGCTGCGCTTCTGGTCGGGGCGCAAGAACGCCTTCCCGGCCGCCGGGCGCATTTCACC
CGACTATTACTGCATGGACGGCACCGTGCCGCGCCGCAGTATTGGCCCGCTGCTCACGCGCATCGAGGCGATGGAGAAGA
TCTACAACTTGCGCTGCATCAACGTCTTCCACGCGGGAGACGGCAACATGCATCCGCTGATCCTGTTCAACGGCAACGAC
CGGGACGAGTGGCACCGGGCCGAAGCGTTCGGTTGCGACATTCTCGAAGCATGCGTGGAACTGGGCGGCACGGTGACCGG
CGAGCACGGCGTCGGCATCGAGAAGATCAATTCCATGTGCGTGCAGTTTTCGCCCGAAGAGCGCGACGCGTTCCACGCGG
TCAAGCGGGCTTTCGACGCGCCTGGCCTCCTGAACCCCGACAAAGGCATTCCCACGCGCGCCCGCTGCGCCGAATACGGC
AAGATGCACGTACGCGGCGGCTTGCTGCCGCATCCGGACCTGCCGCGTTTCTAA

Upstream 100 bases:

>100_bases
CGGGCAAGATCTTCTCCTGGGCGGCTTGAGGCATGGTCAGGCGCGGCTGCATCAGAAAGCCGGCCGCGCCGGACTTGAAA
GGCATGAGGAGACAGGTCAC

Downstream 100 bases:

>100_bases
CATTGCCGTACCCGCCGACGCATTGCGCATAACCCGCGCCGGTGCCGCTGTTCCTGCTTTCACCCTGATTACCCGATACG
GGTCCGCTCCGGGTTGCGAG

Product: D-lactate dehydrogenase (cytochrome)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 497; Mature: 497

Protein sequence:

>497_residues
MNAPAELTAEVLAQRQREVVQALMAVLPTHCLLYREEDTVAYECDGLAAYRRLPLAVALPETESQVQRIVQICHRLDVPI
VPRGAGTGLSGGAMPIRHGVVVSLARLRKIVEVDSYARTATVQPGVRNLSISEAAAPYGLYYAPDPSSQIACTIGGNVSE
NSGGVHCLKYGLTVHNVLRVRAVTMEGEIVEFGSLAPDAPGLDLLAVLIGSEGMFAIVTEVTVKLIPKPQTAQVIMASFD
DVVKGGDAVAGIIAAGIIPAGLEMMDKPATRAVEEFVNAGYDLDAAAILLCESDGTPDEVADEIVRMTAVLREHGATRIQ
ISRSENERLRFWSGRKNAFPAAGRISPDYYCMDGTVPRRSIGPLLTRIEAMEKIYNLRCINVFHAGDGNMHPLILFNGND
RDEWHRAEAFGCDILEACVELGGTVTGEHGVGIEKINSMCVQFSPEERDAFHAVKRAFDAPGLLNPDKGIPTRARCAEYG
KMHVRGGLLPHPDLPRF

Sequences:

>Translated_497_residues
MNAPAELTAEVLAQRQREVVQALMAVLPTHCLLYREEDTVAYECDGLAAYRRLPLAVALPETESQVQRIVQICHRLDVPI
VPRGAGTGLSGGAMPIRHGVVVSLARLRKIVEVDSYARTATVQPGVRNLSISEAAAPYGLYYAPDPSSQIACTIGGNVSE
NSGGVHCLKYGLTVHNVLRVRAVTMEGEIVEFGSLAPDAPGLDLLAVLIGSEGMFAIVTEVTVKLIPKPQTAQVIMASFD
DVVKGGDAVAGIIAAGIIPAGLEMMDKPATRAVEEFVNAGYDLDAAAILLCESDGTPDEVADEIVRMTAVLREHGATRIQ
ISRSENERLRFWSGRKNAFPAAGRISPDYYCMDGTVPRRSIGPLLTRIEAMEKIYNLRCINVFHAGDGNMHPLILFNGND
RDEWHRAEAFGCDILEACVELGGTVTGEHGVGIEKINSMCVQFSPEERDAFHAVKRAFDAPGLLNPDKGIPTRARCAEYG
KMHVRGGLLPHPDLPRF
>Mature_497_residues
MNAPAELTAEVLAQRQREVVQALMAVLPTHCLLYREEDTVAYECDGLAAYRRLPLAVALPETESQVQRIVQICHRLDVPI
VPRGAGTGLSGGAMPIRHGVVVSLARLRKIVEVDSYARTATVQPGVRNLSISEAAAPYGLYYAPDPSSQIACTIGGNVSE
NSGGVHCLKYGLTVHNVLRVRAVTMEGEIVEFGSLAPDAPGLDLLAVLIGSEGMFAIVTEVTVKLIPKPQTAQVIMASFD
DVVKGGDAVAGIIAAGIIPAGLEMMDKPATRAVEEFVNAGYDLDAAAILLCESDGTPDEVADEIVRMTAVLREHGATRIQ
ISRSENERLRFWSGRKNAFPAAGRISPDYYCMDGTVPRRSIGPLLTRIEAMEKIYNLRCINVFHAGDGNMHPLILFNGND
RDEWHRAEAFGCDILEACVELGGTVTGEHGVGIEKINSMCVQFSPEERDAFHAVKRAFDAPGLLNPDKGIPTRARCAEYG
KMHVRGGLLPHPDLPRF

Specific function: Unknown

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI37595756, Length=465, Percent_Identity=27.3118279569892, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI37595754, Length=489, Percent_Identity=26.5848670756646, Blast_Score=180, Evalue=3e-45,
Organism=Homo sapiens, GI119964728, Length=456, Percent_Identity=25.219298245614, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI4501993, Length=222, Percent_Identity=27.027027027027, Blast_Score=84, Evalue=3e-16,
Organism=Escherichia coli, GI1789351, Length=479, Percent_Identity=59.0814196242171, Blast_Score=592, Evalue=1e-170,
Organism=Escherichia coli, GI1787977, Length=497, Percent_Identity=22.9376257545272, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI48994907, Length=444, Percent_Identity=23.4234234234234, Blast_Score=75, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI71992373, Length=425, Percent_Identity=25.6470588235294, Blast_Score=169, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI71992381, Length=425, Percent_Identity=24, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI71992392, Length=358, Percent_Identity=24.8603351955307, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17534361, Length=455, Percent_Identity=24.6153846153846, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17556096, Length=220, Percent_Identity=26.3636363636364, Blast_Score=81, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320027, Length=431, Percent_Identity=25.754060324826, Blast_Score=154, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6320023, Length=460, Percent_Identity=28.695652173913, Blast_Score=154, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6320764, Length=501, Percent_Identity=24.750499001996, Blast_Score=136, Evalue=7e-33,
Organism=Drosophila melanogaster, GI18921117, Length=455, Percent_Identity=28.1318681318681, Blast_Score=132, Evalue=7e-31,
Organism=Drosophila melanogaster, GI24639277, Length=455, Percent_Identity=28.1318681318681, Blast_Score=132, Evalue=7e-31,
Organism=Drosophila melanogaster, GI24639275, Length=455, Percent_Identity=28.1318681318681, Blast_Score=132, Evalue=7e-31,
Organism=Drosophila melanogaster, GI24653753, Length=222, Percent_Identity=25.2252252252252, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR016164
- InterPro:   IPR016168
- InterPro:   IPR004113
- InterPro:   IPR004490
- InterPro:   IPR006094
- InterPro:   IPR016171 [H]

Pfam domain/function: PF02913 FAD-oxidase_C; PF01565 FAD_binding_4 [H]

EC number: NA

Molecular weight: Translated: 53682; Mature: 53682

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPAELTAEVLAQRQREVVQALMAVLPTHCLLYREEDTVAYECDGLAAYRRLPLAVALP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEECCCHHHHHHCCEEEECC
ETESQVQRIVQICHRLDVPIVPRGAGTGLSGGAMPIRHGVVVSLARLRKIVEVDSYARTA
CCHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEE
TVQPGVRNLSISEAAAPYGLYYAPDPSSQIACTIGGNVSENSGGVHCLKYGLTVHNVLRV
ECCCCCCCCCHHHHCCCCCEEECCCCCCCEEEEECCCCCCCCCCEEEEEECCHHHHHHEE
RAVTMEGEIVEFGSLAPDAPGLDLLAVLIGSEGMFAIVTEVTVKLIPKPQTAQVIMASFD
EEEEECCCEEECCCCCCCCCCHHHHHHHHCCCCCEEEEEEHHHEECCCCCHHHHHHHHHH
DVVKGGDAVAGIIAAGIIPAGLEMMDKPATRAVEEFVNAGYDLDAAAILLCESDGTPDEV
HHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHH
ADEIVRMTAVLREHGATRIQISRSENERLRFWSGRKNAFPAAGRISPDYYCMDGTVPRRS
HHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCCCCEEEECCCCCCHH
IGPLLTRIEAMEKIYNLRCINVFHAGDGNMHPLILFNGNDRDEWHRAEAFGCDILEACVE
HHHHHHHHHHHHHHHCEEEEEEEECCCCCCCEEEEECCCCCHHHHHHHHCCHHHHHHHHH
LGGTVTGEHGVGIEKINSMCVQFSPEERDAFHAVKRAFDAPGLLNPDKGIPTRARCAEYG
HCCEEECCCCCCHHHHHHHHEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHC
KMHVRGGLLPHPDLPRF
CEEECCCCCCCCCCCCC
>Mature Secondary Structure
MNAPAELTAEVLAQRQREVVQALMAVLPTHCLLYREEDTVAYECDGLAAYRRLPLAVALP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEECCCHHHHHHCCEEEECC
ETESQVQRIVQICHRLDVPIVPRGAGTGLSGGAMPIRHGVVVSLARLRKIVEVDSYARTA
CCHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEE
TVQPGVRNLSISEAAAPYGLYYAPDPSSQIACTIGGNVSENSGGVHCLKYGLTVHNVLRV
ECCCCCCCCCHHHHCCCCCEEECCCCCCCEEEEECCCCCCCCCCEEEEEECCHHHHHHEE
RAVTMEGEIVEFGSLAPDAPGLDLLAVLIGSEGMFAIVTEVTVKLIPKPQTAQVIMASFD
EEEEECCCEEECCCCCCCCCCHHHHHHHHCCCCCEEEEEEHHHEECCCCCHHHHHHHHHH
DVVKGGDAVAGIIAAGIIPAGLEMMDKPATRAVEEFVNAGYDLDAAAILLCESDGTPDEV
HHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHH
ADEIVRMTAVLREHGATRIQISRSENERLRFWSGRKNAFPAAGRISPDYYCMDGTVPRRS
HHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCCCCEEEECCCCCCHH
IGPLLTRIEAMEKIYNLRCINVFHAGDGNMHPLILFNGNDRDEWHRAEAFGCDILEACVE
HHHHHHHHHHHHHHHCEEEEEEEECCCCCCCEEEEECCCCCHHHHHHHHCCHHHHHHHHH
LGGTVTGEHGVGIEKINSMCVQFSPEERDAFHAVKRAFDAPGLLNPDKGIPTRARCAEYG
HCCEEECCCCCCHHHHHHHHEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHC
KMHVRGGLLPHPDLPRF
CEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]