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The map label for this gene is ubiA [H]

Identifier: 91781862

GI number: 91781862

Start: 536656

End: 537519

Strand: Direct

Name: ubiA [H]

Synonym: Bxe_A3983

Alternate gene names: 91781862

Gene position: 536656-537519 (Clockwise)

Preceding gene: 91781861

Following gene: 91781869

Centisome position: 10.96

GC content: 64.24

Gene sequence:

>864_bases
ATGTTCGCCCGACTTCCCCTGTATCTGCGCCTCGTGCGCATGGACAAGCCGATCGGCAGCCTGCTGCTGCTATGGCCGAC
GCTCAACGCGCTGTGGATCGCGTCGGACGGTCGCCCGTCGTTGCCGCTGCTGGTGATCTTCACGGTGGGCACGGTGCTGA
TGCGCTCGGCGGGTTGCGCGATCAACGACTACGCCGATCGCGATTTCGATCGTTACGTGAGGCGCACGGAGAACCGTCCG
ATCACGTCGGGCAAGATCAGGGCGTGGGAAGCGGTGGCGCTGGCGGCCGCGTTGTCGCTGCTGGCATTTCTGCTGATCCT
GCCGCTGAATGCGCTGACTAAGGAACTCTCGGTGGCGGCGCTCTTCGTCGCCGGTTCGTATCCGTTCACCAAGCGCTTCT
TCGCCATTCCGCAGGCTTATCTGGGCATCGCGTTCGGTTTCGGCATTCCTATGGCGTTCGCCGCGATTCAGAACCACGTG
CCGATGCTCGCGTGGGTGATGCTGCTGGCCAATGTGTTCTGGTCGGTCGCGTACGACACCGAATATGCGATGGTCGACCG
CGACGACGACATCAAGATCGGCATCCGCACTTCGGCGCTGACGTTCGGCCGCTTCGACGTGGCCGCGATCATGCTCTGCT
ACGCGGTGACGCTGGGGATCTACGTGGGCATCGGCGTGCTGCTCGGTTTCGGCGCGCTGTACTGGCTGGGCTGGGCGGCG
GCCGCGGGCTGCGCGATCTATCACTACACGCTGATCCGAAATCGGGAACGGATGGCGTGCTTCGCCGCGTTCCGGCATAA
CAACTGGCTGGGCGGCGCGCTGTTCGCGGGTATCGCCGCGCATTACGCGGCGACGTGGTTCTAG

Upstream 100 bases:

>100_bases
TTTTCTGCGCAGCCTTGTCCGACCTGCTTGCGTCGCGGCGGCCCGCCGTCCGCATCCCGTAAAATAGCCGCACCGTCTCG
CACTTTCACCGACTCCGCCC

Downstream 100 bases:

>100_bases
TTTTTCCGCAGGGCTTTGCGCCGGCTTTGCGCCGGCTTTGCGGTGCTTCATCACTAACGCCGCGGCGGCCTGAATCGAAG
CGCCGCGGCGTTCAGTCCTA

Product: 4-hydroxybenzoate octaprenyltransferase

Products: @OCTA07.txt*3-Octaprenyl-4-Hydroxybenzoate!. [C]

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MFARLPLYLRLVRMDKPIGSLLLLWPTLNALWIASDGRPSLPLLVIFTVGTVLMRSAGCAINDYADRDFDRYVRRTENRP
ITSGKIRAWEAVALAAALSLLAFLLILPLNALTKELSVAALFVAGSYPFTKRFFAIPQAYLGIAFGFGIPMAFAAIQNHV
PMLAWVMLLANVFWSVAYDTEYAMVDRDDDIKIGIRTSALTFGRFDVAAIMLCYAVTLGIYVGIGVLLGFGALYWLGWAA
AAGCAIYHYTLIRNRERMACFAAFRHNNWLGGALFAGIAAHYAATWF

Sequences:

>Translated_287_residues
MFARLPLYLRLVRMDKPIGSLLLLWPTLNALWIASDGRPSLPLLVIFTVGTVLMRSAGCAINDYADRDFDRYVRRTENRP
ITSGKIRAWEAVALAAALSLLAFLLILPLNALTKELSVAALFVAGSYPFTKRFFAIPQAYLGIAFGFGIPMAFAAIQNHV
PMLAWVMLLANVFWSVAYDTEYAMVDRDDDIKIGIRTSALTFGRFDVAAIMLCYAVTLGIYVGIGVLLGFGALYWLGWAA
AAGCAIYHYTLIRNRERMACFAAFRHNNWLGGALFAGIAAHYAATWF
>Mature_287_residues
MFARLPLYLRLVRMDKPIGSLLLLWPTLNALWIASDGRPSLPLLVIFTVGTVLMRSAGCAINDYADRDFDRYVRRTENRP
ITSGKIRAWEAVALAAALSLLAFLLILPLNALTKELSVAALFVAGSYPFTKRFFAIPQAYLGIAFGFGIPMAFAAIQNHV
PMLAWVMLLANVFWSVAYDTEYAMVDRDDDIKIGIRTSALTFGRFDVAAIMLCYAVTLGIYVGIGVLLGFGALYWLGWAA
AAGCAIYHYTLIRNRERMACFAAFRHNNWLGGALFAGIAAHYAATWF

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=276, Percent_Identity=35.1449275362319, Blast_Score=143, Evalue=1e-34,
Organism=Escherichia coli, GI1790473, Length=279, Percent_Identity=52.3297491039427, Blast_Score=275, Evalue=3e-75,
Organism=Caenorhabditis elegans, GI17553718, Length=283, Percent_Identity=33.5689045936396, Blast_Score=139, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI32565247, Length=282, Percent_Identity=32.2695035460993, Blast_Score=129, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17553720, Length=338, Percent_Identity=28.698224852071, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI32565245, Length=141, Percent_Identity=39.7163120567376, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI32565243, Length=136, Percent_Identity=39.7058823529412, Blast_Score=87, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6324370, Length=214, Percent_Identity=34.5794392523364, Blast_Score=114, Evalue=2e-26,
Organism=Drosophila melanogaster, GI21355567, Length=200, Percent_Identity=38.5, Blast_Score=141, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.- [C]

Molecular weight: Translated: 31755; Mature: 31755

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFARLPLYLRLVRMDKPIGSLLLLWPTLNALWIASDGRPSLPLLVIFTVGTVLMRSAGCA
CCCCHHHHHHHHHHCCCHHHHEEHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCC
INDYADRDFDRYVRRTENRPITSGKIRAWEAVALAAALSLLAFLLILPLNALTKELSVAA
CCCHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
LFVAGSYPFTKRFFAIPQAYLGIAFGFGIPMAFAAIQNHVPMLAWVMLLANVFWSVAYDT
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCC
EYAMVDRDDDIKIGIRTSALTFGRFDVAAIMLCYAVTLGIYVGIGVLLGFGALYWLGWAA
EEEEECCCCCEEEEEEECEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAGCAIYHYTLIRNRERMACFAAFRHNNWLGGALFAGIAAHYAATWF
HHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFARLPLYLRLVRMDKPIGSLLLLWPTLNALWIASDGRPSLPLLVIFTVGTVLMRSAGCA
CCCCHHHHHHHHHHCCCHHHHEEHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCC
INDYADRDFDRYVRRTENRPITSGKIRAWEAVALAAALSLLAFLLILPLNALTKELSVAA
CCCHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
LFVAGSYPFTKRFFAIPQAYLGIAFGFGIPMAFAAIQNHVPMLAWVMLLANVFWSVAYDT
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCC
EYAMVDRDDDIKIGIRTSALTFGRFDVAAIMLCYAVTLGIYVGIGVLLGFGALYWLGWAA
EEEEECCCCCEEEEEEECEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAGCAIYHYTLIRNRERMACFAAFRHNNWLGGALFAGIAAHYAATWF
HHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 4-Hydroxybenzoate; Farnesylfarnesylgeraniol [C]

Specific reaction: 4-Hydroxybenzoate + Farnesylfarnesylgeraniol = @OCTA07.txt*3-Octaprenyl-4-Hydroxybenzoate!. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA