Click here to switch to the map view.

The map label for this gene is strD [H]

Identifier: 91781819

GI number: 91781819

Start: 487271

End: 487996

Strand: Reverse

Name: strD [H]

Synonym: Bxe_A4026

Alternate gene names: 91781819

Gene position: 487996-487271 (Counterclockwise)

Preceding gene: 91781820

Following gene: 91781817

Centisome position: 9.97

GC content: 65.29

Gene sequence:

>726_bases
ATGACGATGTCCGTGAAGAAAGCAATGATTTTCGCCGCAGGCCGCGGCGAGCGCATGCGGCCGCTGACCGACACGCGTCC
CAAGCCTTTGCTCGAAGTGGGCGGCAAGCCGCTGATCGTCTGGCAGATCGAACGGCTCGCGCAGGCGGGCTTTCGAACCA
TCGTGATCAACCACGCGTGGCTCGGCGAGCAGATCGAAGCCACCCTCGGCAACGGCTCGCGCTGGCAGGTGGCGTTGCGC
TACTCGCCCGAGCGCGAGGCGCTGGAGACGGCGGGCGGCATCGTGCAGGCGTTGCCGCTGCTCGAAGATAGCGGCGCGAG
TGAAGTGTTCGTCGCGGTCAGCGGCGATGTGTATGCGGACTTCGATTACGCCACGTTGAATGCGCGCGCGGAGAAGCTCG
CCGCATTGCCCGAACCGGGCATGCATCTCGTGATGGTGCCTAATCCGGCGTTTCATCCTGAAGGCGACTTCGGTCTGGCT
GACGGCGCGCTGTCGCTCGAAGCGCAGCCGCGCTTCACGTTCGGCAACATCGGTCTTTACGACACCCGCATGTTCCGTGA
TTTGCCGCGCGACACGCGGCGCGCGCTCACGCCGTATTACCGCGAGACGATTGCACGCGGTCTGGCGAGTGGCGAGTTGT
ACGAGGGCTTGTGGGAGAACGTCGGCACGCCCGCTCAGTTGGGGGAACTGGATCAGCGTTTGCGCGCGGCAGGAGCCGGG
AGCTAG

Upstream 100 bases:

>100_bases
GCGCAAGGTCGCCGAACGCTATGCGCCGCTGCGTCCGTTCGCGAGGCTGCTCGACGATCTCGAAGGCCGCGCGAATGAAG
TCGGCTACACCTTCTGACCG

Downstream 100 bases:

>100_bases
GCGTTTGGCGTTTGGCGTTTGGCGTTTGGCGTTTGGCGTTTGGCGTTTGGCGTTTGGCGTTTGGCGTTTGGCGTTTGGCG
TTTGGCGCCAAAGCCTGGCG

Product: putative nucleotidyl transferase

Products: NA

Alternate protein names: Sugar-nucleotidylation enzyme; dTDP-glucose pyrophosphorylase; dTDP-glucose synthase [H]

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MTMSVKKAMIFAAGRGERMRPLTDTRPKPLLEVGGKPLIVWQIERLAQAGFRTIVINHAWLGEQIEATLGNGSRWQVALR
YSPEREALETAGGIVQALPLLEDSGASEVFVAVSGDVYADFDYATLNARAEKLAALPEPGMHLVMVPNPAFHPEGDFGLA
DGALSLEAQPRFTFGNIGLYDTRMFRDLPRDTRRALTPYYRETIARGLASGELYEGLWENVGTPAQLGELDQRLRAAGAG
S

Sequences:

>Translated_241_residues
MTMSVKKAMIFAAGRGERMRPLTDTRPKPLLEVGGKPLIVWQIERLAQAGFRTIVINHAWLGEQIEATLGNGSRWQVALR
YSPEREALETAGGIVQALPLLEDSGASEVFVAVSGDVYADFDYATLNARAEKLAALPEPGMHLVMVPNPAFHPEGDFGLA
DGALSLEAQPRFTFGNIGLYDTRMFRDLPRDTRRALTPYYRETIARGLASGELYEGLWENVGTPAQLGELDQRLRAAGAG
S
>Mature_240_residues
TMSVKKAMIFAAGRGERMRPLTDTRPKPLLEVGGKPLIVWQIERLAQAGFRTIVINHAWLGEQIEATLGNGSRWQVALRY
SPEREALETAGGIVQALPLLEDSGASEVFVAVSGDVYADFDYATLNARAEKLAALPEPGMHLVMVPNPAFHPEGDFGLAD
GALSLEAQPRFTFGNIGLYDTRMFRDLPRDTRRALTPYYRETIARGLASGELYEGLWENVGTPAQLGELDQRLRAAGAGS

Specific function: Involved in the biosynthesis of the streptose moiety of streptomycin. Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis [H]

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucose-1-phosphate thymidylyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=121, Percent_Identity=32.2314049586777, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI11761619, Length=121, Percent_Identity=32.2314049586777, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI133931050, Length=239, Percent_Identity=29.7071129707113, Blast_Score=80, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6320148, Length=121, Percent_Identity=36.3636363636364, Blast_Score=70, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21355443, Length=121, Percent_Identity=37.1900826446281, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24644084, Length=121, Percent_Identity=37.1900826446281, Blast_Score=79, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005908
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.24 [H]

Molecular weight: Translated: 26342; Mature: 26211

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMSVKKAMIFAAGRGERMRPLTDTRPKPLLEVGGKPLIVWQIERLAQAGFRTIVINHAW
CCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHCCCCEEEEEEHHHHHHCCCEEEEEECCC
LGEQIEATLGNGSRWQVALRYSPEREALETAGGIVQALPLLEDSGASEVFVAVSGDVYAD
CCCHHHHCCCCCCEEEEEEEECCCHHHHHHHCCHHHHHHHHCCCCCCEEEEEECCCEEEC
FDYATLNARAEKLAALPEPGMHLVMVPNPAFHPEGDFGLADGALSLEAQPRFTFGNIGLY
CCEEEHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCEEEECCCCCEEECCCCCH
DTRMFRDLPRDTRRALTPYYRETIARGLASGELYEGLWENVGTPAQLGELDQRLRAAGAG
HHHHHHHCCHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCC
S
C
>Mature Secondary Structure 
TMSVKKAMIFAAGRGERMRPLTDTRPKPLLEVGGKPLIVWQIERLAQAGFRTIVINHAW
CCCCCEEEEEECCCCCCCCCCCCCCCCCHHHCCCCEEEEEEHHHHHHCCCEEEEEECCC
LGEQIEATLGNGSRWQVALRYSPEREALETAGGIVQALPLLEDSGASEVFVAVSGDVYAD
CCCHHHHCCCCCCEEEEEEEECCCHHHHHHHCCHHHHHHHHCCCCCCEEEEEECCCEEEC
FDYATLNARAEKLAALPEPGMHLVMVPNPAFHPEGDFGLADGALSLEAQPRFTFGNIGLY
CCEEEHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCEEEECCCCCEEECCCCCH
DTRMFRDLPRDTRRALTPYYRETIARGLASGELYEGLWENVGTPAQLGELDQRLRAAGAG
HHHHHHHCCHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCC
S
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3118332 [H]