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The map label for this gene is hexR [H]

Identifier: 91781786

GI number: 91781786

Start: 446101

End: 446988

Strand: Direct

Name: hexR [H]

Synonym: Bxe_A4059

Alternate gene names: 91781786

Gene position: 446101-446988 (Clockwise)

Preceding gene: 91781784

Following gene: 91781787

Centisome position: 9.11

GC content: 67.79

Gene sequence:

>888_bases
ATGAACTCAACCGCCGAACCGCTGGCTTTCGACATCGTCGCGCGCATTGCCGAATGCGCGCCCGAGCTGCGCTCGGCCGA
ACGCAAGGTCGCCGCGCTGATTCTCGACGATCTGACCGGCGCCTCGCGCGCCAGCATCGGCGCGCTCGCGCAGCAGGCCG
AGGTGAGCGTCGCGACCGTGACGCGCTTTGCCAAGGCGGTGGGTTGCCGCGACGTGCGCGAACTCAAGCTGCGGCTGGCG
CAGGCCGCGGCGGTCGGTCAGCGCTTCCTGCAGCCAGGCCCGAGCGGCGCGCCTGAGCCGATCGCGACCCGGGTGTTCGA
CGAATTGCAGACCACGCTGGCGCACAACCATCAGTTGCTGCGCCAGGCGCCGCTCGGCGAAGCGGCTGCCGCCTTGCGCG
CTGCACGCATGATCTACGTGTTCGGCATGGGTGGCGGTTCCACCGCGCTCGCCGACGAGATGCGCTTCAGGCTCGTGCGT
CTCGGCCGGCCCGTGGCGACCTATCAGGACGGCTTGCTGCAACGCATGGTGGCGAGCACCGTGTCGCGTGACTGTGTGGT
GATCGCGCTGTCCACCACGGGGCGTGTGCCCGAGATGGTCGAAAACTGCAAGATCGCGCGCAGCTACGGCGCGACCGTGG
TCGCGCTGACCGCGCCGGCTTCGCCGCTTGCGAGGCTGGCCGATTGGGTGATCCCGATCGTCGCGTTTGAAACTGATTTC
ATTTACAAGCCGTCGTCGTCGCGCTACGCAATGATGATGGCGCTCGATGTGCTCGTCACCGAACTCGCCGTCAGTCAGGG
CGACGAGAGCCGCGAACTGCTGCGCCGCATGAAGCATGCGCTCGACACGCACCGCGGCGGCGGCGATCGACAACCGTTAG
GAGACTGA

Upstream 100 bases:

>100_bases
CGAAAGTACGATGGATGAAGAAATGTTATTTAGTACCACGGTTTGCCGGAGGCGCGTTGTCAGCCTTCGTTGAGCCTTCG
CGCCACATCCACAGTCCGCA

Downstream 100 bases:

>100_bases
TCCATGCATTCGCATCCCGAAGCCGCCGATACGCTGATCTTCGGCGCGCAACTGTACGACGGCACGGGCGCGCCGCCGGT
CGAGCGCGATGTCGCGGTGC

Product: RpiR family transcriptional regulator

Products: NA

Alternate protein names: Hex regulon repressor [H]

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MNSTAEPLAFDIVARIAECAPELRSAERKVAALILDDLTGASRASIGALAQQAEVSVATVTRFAKAVGCRDVRELKLRLA
QAAAVGQRFLQPGPSGAPEPIATRVFDELQTTLAHNHQLLRQAPLGEAAAALRAARMIYVFGMGGGSTALADEMRFRLVR
LGRPVATYQDGLLQRMVASTVSRDCVVIALSTTGRVPEMVENCKIARSYGATVVALTAPASPLARLADWVIPIVAFETDF
IYKPSSSRYAMMMALDVLVTELAVSQGDESRELLRRMKHALDTHRGGGDRQPLGD

Sequences:

>Translated_295_residues
MNSTAEPLAFDIVARIAECAPELRSAERKVAALILDDLTGASRASIGALAQQAEVSVATVTRFAKAVGCRDVRELKLRLA
QAAAVGQRFLQPGPSGAPEPIATRVFDELQTTLAHNHQLLRQAPLGEAAAALRAARMIYVFGMGGGSTALADEMRFRLVR
LGRPVATYQDGLLQRMVASTVSRDCVVIALSTTGRVPEMVENCKIARSYGATVVALTAPASPLARLADWVIPIVAFETDF
IYKPSSSRYAMMMALDVLVTELAVSQGDESRELLRRMKHALDTHRGGGDRQPLGD
>Mature_295_residues
MNSTAEPLAFDIVARIAECAPELRSAERKVAALILDDLTGASRASIGALAQQAEVSVATVTRFAKAVGCRDVRELKLRLA
QAAAVGQRFLQPGPSGAPEPIATRVFDELQTTLAHNHQLLRQAPLGEAAAALRAARMIYVFGMGGGSTALADEMRFRLVR
LGRPVATYQDGLLQRMVASTVSRDCVVIALSTTGRVPEMVENCKIARSYGATVVALTAPASPLARLADWVIPIVAFETDF
IYKPSSSRYAMMMALDVLVTELAVSQGDESRELLRRMKHALDTHRGGGDRQPLGD

Specific function: Represses the expression of the hex regulon (zwf, eda, glp and gap) [H]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788159, Length=286, Percent_Identity=33.5664335664336, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1788767, Length=279, Percent_Identity=26.1648745519713, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI87082369, Length=230, Percent_Identity=25.2173913043478, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 31670; Mature: 31670

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSTAEPLAFDIVARIAECAPELRSAERKVAALILDDLTGASRASIGALAQQAEVSVATV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
TRFAKAVGCRDVRELKLRLAQAAAVGQRFLQPGPSGAPEPIATRVFDELQTTLAHNHQLL
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RQAPLGEAAAALRAARMIYVFGMGGGSTALADEMRFRLVRLGRPVATYQDGLLQRMVAST
HHCCCCHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
VSRDCVVIALSTTGRVPEMVENCKIARSYGATVVALTAPASPLARLADWVIPIVAFETDF
HCCCEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCE
IYKPSSSRYAMMMALDVLVTELAVSQGDESRELLRRMKHALDTHRGGGDRQPLGD
EECCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MNSTAEPLAFDIVARIAECAPELRSAERKVAALILDDLTGASRASIGALAQQAEVSVATV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
TRFAKAVGCRDVRELKLRLAQAAAVGQRFLQPGPSGAPEPIATRVFDELQTTLAHNHQLL
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RQAPLGEAAAALRAARMIYVFGMGGGSTALADEMRFRLVRLGRPVATYQDGLLQRMVAST
HHCCCCHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
VSRDCVVIALSTTGRVPEMVENCKIARSYGATVVALTAPASPLARLADWVIPIVAFETDF
HCCCEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCE
IYKPSSSRYAMMMALDVLVTELAVSQGDESRELLRRMKHALDTHRGGGDRQPLGD
EECCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]