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The map label for this gene is glcR [H]

Identifier: 91781642

GI number: 91781642

Start: 291486

End: 292256

Strand: Reverse

Name: glcR [H]

Synonym: Bxe_A4204

Alternate gene names: 91781642

Gene position: 292256-291486 (Counterclockwise)

Preceding gene: 91781652

Following gene: 91781640

Centisome position: 5.97

GC content: 64.59

Gene sequence:

>771_bases
ATGTGGCAGGAAGACCGTCATCAGAGAATTCGAGCGTTGCTGTCCACGCTTCAACGCGTGTCCACGGAACGGATCATGGC
GGACCTCGGGGTGTCGCGCGAAACCGTGCGGCGCGATCTGCTCGACCTCGAAGCGCTCGGTGAACTGCGGCGCGTGCATG
GCGGCGCGATCAAGCCCGCGGACGAAGCGCCGATCGCCGAGCGCGTGCACATGCGCGTCAAATCCAAAACCGCCATCGCG
AAGGCGGCTACAGGATTGATCGCGAGCGGCCAGACGCTTTTCATCGACGCCGGCACCACCACCACCGCGCTGGCCGAGGA
ACTGGCGAAGCTCGCGAACCTCACCGTCGTCACCAATTCGATCGACGTCGCGCTGAAGATGCGCGGAGCGGTCGATCAGG
CCGAAGCCGCCAACGAAGTCATCCTGCTCGGCGGCTCGATCAGCGACCGCGCGATGGCGACCACCGGCGCCACCACCGTG
CTCGACATCCAGCGCTATCGCGCGGACCTTGCGCTGCTGTCGCCCGTCGGCGTCGATCACCGGCATGGCGCGACCAACTA
CGACCACGCCGAAACCGAAGTGGCGCGCGCGATGGTCGCCAACGCCGACCGCGTGGTGATCCTCGCCGATTACAGCAAGA
TCGGCCAGCGCAGCCGTATTTCCTACTGCCCAGTCGATCGCATCGACGTGCTCGTCACCAACAAGAAGGCGGCCGAAGCC
GCCGATTTTGCGTCGCTGAAAAAGAAGCTCGAAGAGATCGTTCTCGCTTAG

Upstream 100 bases:

>100_bases
AAGTAGTACGCTTGACATCGTCCGGACACACATTCGTGACCACGATGTCGCAGTTAACAACAAGCTAAACAAACGCGCGT
ACGCATCCAGGGAAACATGT

Downstream 100 bases:

>100_bases
GGTCGAGGCCTGTACCCGGGGCTCGATGCGAGGTGCGAGGTGCGAGGTGCGAGGTGCGAGGTGCGAGGTGCGAGGTGCGA
GGTGCGAGGTGCGAGGCGTA

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MWQEDRHQRIRALLSTLQRVSTERIMADLGVSRETVRRDLLDLEALGELRRVHGGAIKPADEAPIAERVHMRVKSKTAIA
KAATGLIASGQTLFIDAGTTTTALAEELAKLANLTVVTNSIDVALKMRGAVDQAEAANEVILLGGSISDRAMATTGATTV
LDIQRYRADLALLSPVGVDHRHGATNYDHAETEVARAMVANADRVVILADYSKIGQRSRISYCPVDRIDVLVTNKKAAEA
ADFASLKKKLEEIVLA

Sequences:

>Translated_256_residues
MWQEDRHQRIRALLSTLQRVSTERIMADLGVSRETVRRDLLDLEALGELRRVHGGAIKPADEAPIAERVHMRVKSKTAIA
KAATGLIASGQTLFIDAGTTTTALAEELAKLANLTVVTNSIDVALKMRGAVDQAEAANEVILLGGSISDRAMATTGATTV
LDIQRYRADLALLSPVGVDHRHGATNYDHAETEVARAMVANADRVVILADYSKIGQRSRISYCPVDRIDVLVTNKKAAEA
ADFASLKKKLEEIVLA
>Mature_256_residues
MWQEDRHQRIRALLSTLQRVSTERIMADLGVSRETVRRDLLDLEALGELRRVHGGAIKPADEAPIAERVHMRVKSKTAIA
KAATGLIASGQTLFIDAGTTTTALAEELAKLANLTVVTNSIDVALKMRGAVDQAEAANEVILLGGSISDRAMATTGATTV
LDIQRYRADLALLSPVGVDHRHGATNYDHAETEVARAMVANADRVVILADYSKIGQRSRISYCPVDRIDVLVTNKKAAEA
ADFASLKKKLEEIVLA

Specific function: Plays a role in carbon catabolite repression (CCR). Specifically required for transcriptional repression of the levanase operon by glucose but not by other sugars [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=236, Percent_Identity=31.7796610169492, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1789059, Length=232, Percent_Identity=27.5862068965517, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1788069, Length=238, Percent_Identity=27.7310924369748, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1787540, Length=243, Percent_Identity=30.4526748971193, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1789519, Length=256, Percent_Identity=27.34375, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1790635, Length=241, Percent_Identity=27.3858921161826, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI226510968, Length=253, Percent_Identity=28.0632411067194, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI87082344, Length=257, Percent_Identity=28.0155642023346, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1787063, Length=240, Percent_Identity=28.3333333333333, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1789170, Length=237, Percent_Identity=24.8945147679325, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27688; Mature: 27688

Theoretical pI: Translated: 7.77; Mature: 7.77

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWQEDRHQRIRALLSTLQRVSTERIMADLGVSRETVRRDLLDLEALGELRRVHGGAIKPA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
DEAPIAERVHMRVKSKTAIAKAATGLIASGQTLFIDAGTTTTALAEELAKLANLTVVTNS
CCCCHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEECCCHHHHHHHHHHHHHCEEEEECC
IDVALKMRGAVDQAEAANEVILLGGSISDRAMATTGATTVLDIQRYRADLALLSPVGVDH
CEEEEEECCCCCHHHCCCCEEEECCCCCCCCEECCCCHHHHHHHHHHHHHHHCCCCCCCC
RHGATNYDHAETEVARAMVANADRVVILADYSKIGQRSRISYCPVDRIDVLVTNKKAAEA
CCCCCCCCHHHHHHHHHHHCCCCEEEEEECCHHCCCCCCCCCCCCCCEEEEEECCHHHHH
ADFASLKKKLEEIVLA
HHHHHHHHHHHHHHCC
>Mature Secondary Structure
MWQEDRHQRIRALLSTLQRVSTERIMADLGVSRETVRRDLLDLEALGELRRVHGGAIKPA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
DEAPIAERVHMRVKSKTAIAKAATGLIASGQTLFIDAGTTTTALAEELAKLANLTVVTNS
CCCCHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEECCCHHHHHHHHHHHHHCEEEEECC
IDVALKMRGAVDQAEAANEVILLGGSISDRAMATTGATTVLDIQRYRADLALLSPVGVDH
CEEEEEECCCCCHHHCCCCEEEECCCCCCCCEECCCCHHHHHHHHHHHHHHHCCCCCCCC
RHGATNYDHAETEVARAMVANADRVVILADYSKIGQRSRISYCPVDRIDVLVTNKKAAEA
CCCCCCCCHHHHHHHHHHHCCCCEEEEEECCHHCCCCCCCCCCCCCCEEEEEECCHHHHH
ADFASLKKKLEEIVLA
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]