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The map label for this gene is dppA [H]

Identifier: 91781596

GI number: 91781596

Start: 245908

End: 247494

Strand: Reverse

Name: dppA [H]

Synonym: Bxe_A4250

Alternate gene names: 91781596

Gene position: 247494-245908 (Counterclockwise)

Preceding gene: 91781597

Following gene: 91781594

Centisome position: 5.06

GC content: 61.18

Gene sequence:

>1587_bases
ATGCGCTTCAAACTGCTCGCAGCCGCCGTACTGTTCACGGCGCCCGCGCTCGTGCTCGCCAAACCGCTGACCGTCTGTAC
CGAGTCGAGCCCCGACGGCTTCGATGTCGTGCAGTTCAATTCGCTCGTCACGACCAATGCGTCGGCCGACGTGATCTTCA
ACTCGCTGGTCTCGTACGACGAGGCCGCGAAGAAAGTGGTACCGGCGCTGGCCGACAAGTGGGACGTGAGTGCCGACGGC
CTCACGTACACGTTCCATCTGCGCCCCAACGTGCAGTTCCAGACCACCGACTACTTCAAGCCCACCCGGCCGCTGAATGC
CGACGACGTCGTCTTCACGTTCGAGCGCATGCTCGACGACAGCAATCCGTGGCACAAGGTAGCGGGCGCGAGCGGCTTCC
CGCATGCGCAGTCGATGGGCCTGCCGAAGCTCATCAAATCCATCAGCAAGGTCGACGACAACACCGTCAAGTTCGAACTG
AACGCGCCGGACGCAACCTTCGTGTCGATCCTCACAATGGGTTTCGCCTCGATCTATTCGGCTGAATACGCCGACCAGTT
GCTCAAGGCCGGCAAGCAGGCCGATCTGAATTCGAAGCCGATCGGCACGGGTCCGTTCGAACTGAAGAGCTATACGAAAG
ACGCCGTGATCCGCTACGACGTGAACCCGGCCTACTGGGGTCCAAAGCCGAAGATCGACCGCCTGATCTATGCGATCACG
CCGGACGCCACGGTGCGGGCGCAAAAGGTGAAAGCGGGCGAATGCCAGATCGCCTTGTCGCCGAAGCCGCAGGATCTTGC
CGAAGCGAAAAGCGACAAGTCGCTCGCCATCGTGCAGACGCCGGCCTTCATGACGGCGTTCGTCGCGTTGAACACGCAAA
AGAAGCCGCTCGACAACCAGAAGGTGCGCGCGGCACTGAACATGGCGTTCGACCGCACCACGTATCTGAAGACGGTGTTC
GACAACACGGCGACGCCGGCCGTGAACCCGTATCCGCCGAACACGTGGAGCTACAACAAGTCCGTGAAGGCGTGGCCGTA
CGACCCGGCAAAGGCAAAGAAACTGCTCGCCGACGCGGGCTATCCGAACGGCTTCGAAACGACCATCTGGGTACGCCCGA
ACGGCAGCGTGCTGAATCCGAATCCGAAGGCCGGCGCGGAACTGCTGCAAGCCGACTTCGCGAAGATCGGCGTGAAGGCC
GAGGTGAAGGTGATCGAGTGGGGTGAACTGATCAAGGAGGCCAAGCAAGGCCAGCATGATTCGCTGTTCATGGGCTGGGC
GGGCGACAACGGCGATCCGGATAATTACCTCTCGCCGCTGTTCAGCTGCAACGCGGTGAAATCGGGCATCAACTTCGCGC
GTTTCTGCGATCAGGATCTGGACAAGCTGATTGCGGACGGCAAGGCAACGCCGGATCAGTCAAAGCGCGCGAAAGCCTAT
GAGCAGGCGCAGCAGGTCATTCACGATCAGGCGTTGTGGATTCCGCTGGGCTATCCGACCGCGGCGGCGATCACGCGTAC
GAACGTGAGCGGCTATCACGTGAGTCCGTTTGGACGGCAGAACTTCGGGACGGTGTCGGTGCAGTAA

Upstream 100 bases:

>100_bases
AAAGAAGGCGGCTACGCTGGACAGCCGCCCATTTCTCGTCAACGGAACATAACCACACAACCAGACGCACTGCCTGACTG
CGCTCGTTATGGGAGATCCT

Downstream 100 bases:

>100_bases
TCGCTTCTGCGTGTGAACGCGCAGAAAAAAGCCCGGTTGCGTCAGCACCGGGCTTTTTTATCTGCGCGCCACCCGCGATC
ACGCGGGCGAAAACCGTATC

Product: peptide ABC transporter periplasmic ligand-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 528; Mature: 528

Protein sequence:

>528_residues
MRFKLLAAAVLFTAPALVLAKPLTVCTESSPDGFDVVQFNSLVTTNASADVIFNSLVSYDEAAKKVVPALADKWDVSADG
LTYTFHLRPNVQFQTTDYFKPTRPLNADDVVFTFERMLDDSNPWHKVAGASGFPHAQSMGLPKLIKSISKVDDNTVKFEL
NAPDATFVSILTMGFASIYSAEYADQLLKAGKQADLNSKPIGTGPFELKSYTKDAVIRYDVNPAYWGPKPKIDRLIYAIT
PDATVRAQKVKAGECQIALSPKPQDLAEAKSDKSLAIVQTPAFMTAFVALNTQKKPLDNQKVRAALNMAFDRTTYLKTVF
DNTATPAVNPYPPNTWSYNKSVKAWPYDPAKAKKLLADAGYPNGFETTIWVRPNGSVLNPNPKAGAELLQADFAKIGVKA
EVKVIEWGELIKEAKQGQHDSLFMGWAGDNGDPDNYLSPLFSCNAVKSGINFARFCDQDLDKLIADGKATPDQSKRAKAY
EQAQQVIHDQALWIPLGYPTAAAITRTNVSGYHVSPFGRQNFGTVSVQ

Sequences:

>Translated_528_residues
MRFKLLAAAVLFTAPALVLAKPLTVCTESSPDGFDVVQFNSLVTTNASADVIFNSLVSYDEAAKKVVPALADKWDVSADG
LTYTFHLRPNVQFQTTDYFKPTRPLNADDVVFTFERMLDDSNPWHKVAGASGFPHAQSMGLPKLIKSISKVDDNTVKFEL
NAPDATFVSILTMGFASIYSAEYADQLLKAGKQADLNSKPIGTGPFELKSYTKDAVIRYDVNPAYWGPKPKIDRLIYAIT
PDATVRAQKVKAGECQIALSPKPQDLAEAKSDKSLAIVQTPAFMTAFVALNTQKKPLDNQKVRAALNMAFDRTTYLKTVF
DNTATPAVNPYPPNTWSYNKSVKAWPYDPAKAKKLLADAGYPNGFETTIWVRPNGSVLNPNPKAGAELLQADFAKIGVKA
EVKVIEWGELIKEAKQGQHDSLFMGWAGDNGDPDNYLSPLFSCNAVKSGINFARFCDQDLDKLIADGKATPDQSKRAKAY
EQAQQVIHDQALWIPLGYPTAAAITRTNVSGYHVSPFGRQNFGTVSVQ
>Mature_528_residues
MRFKLLAAAVLFTAPALVLAKPLTVCTESSPDGFDVVQFNSLVTTNASADVIFNSLVSYDEAAKKVVPALADKWDVSADG
LTYTFHLRPNVQFQTTDYFKPTRPLNADDVVFTFERMLDDSNPWHKVAGASGFPHAQSMGLPKLIKSISKVDDNTVKFEL
NAPDATFVSILTMGFASIYSAEYADQLLKAGKQADLNSKPIGTGPFELKSYTKDAVIRYDVNPAYWGPKPKIDRLIYAIT
PDATVRAQKVKAGECQIALSPKPQDLAEAKSDKSLAIVQTPAFMTAFVALNTQKKPLDNQKVRAALNMAFDRTTYLKTVF
DNTATPAVNPYPPNTWSYNKSVKAWPYDPAKAKKLLADAGYPNGFETTIWVRPNGSVLNPNPKAGAELLQADFAKIGVKA
EVKVIEWGELIKEAKQGQHDSLFMGWAGDNGDPDNYLSPLFSCNAVKSGINFARFCDQDLDKLIADGKATPDQSKRAKAY
EQAQQVIHDQALWIPLGYPTAAAITRTNVSGYHVSPFGRQNFGTVSVQ

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=526, Percent_Identity=46.1977186311787, Blast_Score=504, Evalue=1e-144,
Organism=Escherichia coli, GI1787551, Length=500, Percent_Identity=34.6, Blast_Score=323, Evalue=2e-89,
Organism=Escherichia coli, GI1787052, Length=520, Percent_Identity=31.3461538461538, Blast_Score=229, Evalue=3e-61,
Organism=Escherichia coli, GI1787762, Length=474, Percent_Identity=24.6835443037975, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1789887, Length=496, Percent_Identity=26.4112903225806, Blast_Score=129, Evalue=6e-31,
Organism=Escherichia coli, GI1787495, Length=537, Percent_Identity=23.8361266294227, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI87081878, Length=485, Percent_Identity=25.360824742268, Blast_Score=112, Evalue=8e-26,
Organism=Escherichia coli, GI1789397, Length=489, Percent_Identity=23.9263803680982, Blast_Score=98, Evalue=2e-21,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 57796; Mature: 57796

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFKLLAAAVLFTAPALVLAKPLTVCTESSPDGFDVVQFNSLVTTNASADVIFNSLVSYD
CCHHHHHHHHHHHCCHHHHHCCHHEEECCCCCCCEEEEECCEEECCCCHHHHHHHHHHHH
EAAKKVVPALADKWDVSADGLTYTFHLRPNVQFQTTDYFKPTRPLNADDVVFTFERMLDD
HHHHHHHHHHHHCCCCCCCCEEEEEEECCCEEEEECCCCCCCCCCCCCHHHHHHHHHHCC
SNPWHKVAGASGFPHAQSMGLPKLIKSISKVDDNTVKFELNAPDATFVSILTMGFASIYS
CCCHHHHCCCCCCCCHHHCCHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
AEYADQLLKAGKQADLNSKPIGTGPFELKSYTKDAVIRYDVNPAYWGPKPKIDRLIYAIT
HHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCEEEEEECCCCCCCCCCCCCEEEEEEC
PDATVRAQKVKAGECQIALSPKPQDLAEAKSDKSLAIVQTPAFMTAFVALNTQKKPLDNQ
CCCEEEEEEECCCCEEEEECCCCHHHHHCCCCCCEEEEECCHHHEEHHEECCCCCCCCHH
KVRAALNMAFDRTTYLKTVFDNTATPAVNPYPPNTWSYNKSVKAWPYDPAKAKKLLADAG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCC
YPNGFETTIWVRPNGSVLNPNPKAGAELLQADFAKIGVKAEVKVIEWGELIKEAKQGQHD
CCCCCCEEEEECCCCCEECCCCHHHHHHHHHHHHHCCCEEEEEEEHHHHHHHHHHCCCCC
SLFMGWAGDNGDPDNYLSPLFSCNAVKSGINFARFCDQDLDKLIADGKATPDQSKRAKAY
CEEEEECCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
EQAQQVIHDQALWIPLGYPTAAAITRTNVSGYHVSPFGRQNFGTVSVQ
HHHHHHHHCCEEEEEECCCCHHEEEECCCCCEEECCCCCCCCCEEEEC
>Mature Secondary Structure
MRFKLLAAAVLFTAPALVLAKPLTVCTESSPDGFDVVQFNSLVTTNASADVIFNSLVSYD
CCHHHHHHHHHHHCCHHHHHCCHHEEECCCCCCCEEEEECCEEECCCCHHHHHHHHHHHH
EAAKKVVPALADKWDVSADGLTYTFHLRPNVQFQTTDYFKPTRPLNADDVVFTFERMLDD
HHHHHHHHHHHHCCCCCCCCEEEEEEECCCEEEEECCCCCCCCCCCCCHHHHHHHHHHCC
SNPWHKVAGASGFPHAQSMGLPKLIKSISKVDDNTVKFELNAPDATFVSILTMGFASIYS
CCCHHHHCCCCCCCCHHHCCHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
AEYADQLLKAGKQADLNSKPIGTGPFELKSYTKDAVIRYDVNPAYWGPKPKIDRLIYAIT
HHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCEEEEEECCCCCCCCCCCCCEEEEEEC
PDATVRAQKVKAGECQIALSPKPQDLAEAKSDKSLAIVQTPAFMTAFVALNTQKKPLDNQ
CCCEEEEEEECCCCEEEEECCCCHHHHHCCCCCCEEEEECCHHHEEHHEECCCCCCCCHH
KVRAALNMAFDRTTYLKTVFDNTATPAVNPYPPNTWSYNKSVKAWPYDPAKAKKLLADAG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCC
YPNGFETTIWVRPNGSVLNPNPKAGAELLQADFAKIGVKAEVKVIEWGELIKEAKQGQHD
CCCCCCEEEEECCCCCEECCCCHHHHHHHHHHHHHCCCEEEEEEEHHHHHHHHHHCCCCC
SLFMGWAGDNGDPDNYLSPLFSCNAVKSGINFARFCDQDLDKLIADGKATPDQSKRAKAY
CEEEEECCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
EQAQQVIHDQALWIPLGYPTAAAITRTNVSGYHVSPFGRQNFGTVSVQ
HHHHHHHHCCEEEEEECCCCHHEEEECCCCCEEECCCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]