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The map label for this gene is mdtA [H]

Identifier: 91781483

GI number: 91781483

Start: 116909

End: 118312

Strand: Reverse

Name: mdtA [H]

Synonym: Bxe_A4363

Alternate gene names: 91781483

Gene position: 118312-116909 (Counterclockwise)

Preceding gene: 91781484

Following gene: 91781482

Centisome position: 2.42

GC content: 66.81

Gene sequence:

>1404_bases
ATGGAAGGACAACGTCCAGACAGCTCCGGCACCACGCGCGATCCGGCGAAGACAAAGCGCGCACGCTGGATCGCCGTCGC
GGTCGCCGTGGCGGTCATTGCGCTCGCGGCACAAGGTATCTGGTCGCGTCACGACGCGCATGCGGCGCTCGAACGCGATG
CCGAGCACGCCAGCCAGACGAGCGTCGAAGTCGTGCGGCCGCAGAAATCGACGGCCGGACTCGATCTCGTGCTGCCCGGC
AACGTACAGGCGTTTCTCGACACGCCGATTTACGCCCGCACCAACGGCTATTTGAAGAAGTGGTACGCGGATATCGGCGC
GAAGGTGAAAAACGGTCAGTTGCTGGCGGAGATCGACACGCCGGAAGTGGACGATCAACTGCGCGCGGCCCGCGCCGATC
TCGCGAATGCCGAGGCCAACTATGCGCTCGCGAAAAGCACCGCCGCGCGCTGGACCGAGATGCTGAAAAGCAAATCGGTC
TCGAAGCAGGAAACCGACGAAAAGGTCGGCGACATGCTCGCAAAGAAAGCCACGCTCGACGCCGCGCGCTTCAACGTGGC
GCGACTCGAGAAAACGCAGTCGTTCCAGAAAGTGTATGCGCCGTTCGACGGCATCGTGACGGCGCGCAATGTCGATGTCG
GCGCGCTGATCGACGCGGGCAGTTCGGGCGGCCCGGCAAAGGAGCTGTTTCACGTCGCGCAGGCGGATCGGCTGCGCGTT
TATGTGAACGTGCCGCAGGCCTACGCGCAGCAGGTTCGCGCGCGGCAGACCGCGTTCCTGACGCTGACCGAGACGCCGTC
GCGACATTATCCGGGCACCGTGGCGCGCACCGCGGGCGCCGTCGATCCGCAACAGCGCACGATGCTGGTGGAAGTCGACG
TCGACAACCGTAACGGCGATTTGCTGCCGGGCGCGTATGCGCAAGTGCACTTCGAATTGGGCACAGGCGCGGCGCCGTTC
ACGCTGCCCGGTAACGCGCTGCTGTTCCGCCCGGATGGCGTGAAACTCGCGACCGTCGACGCGCAGCACAAGGTGAAGCT
GATCGCGGTGTCGCTGGGAACGGACTTCGGCACGCGTGTCGCGATTGCGTCCGGCCTGCAGGGCGATGAGCAGGTGATCC
TGAATCCGCAGGACTCGATCATCGACGGCGCGCCGGTGCGGATCGTGGCGGCGAAAGCGGGAACTGCCACGGGCGCGTCA
GGAGCGACCGGTGCTTCCGGCTCGGCGGCGGGTGGTGAGGGCACGGCGGGCGCATCCGGCGCCGCGGCGAGCCGCGATGG
TGCGGCAAGCGCCAGCGGCGCAGCCGCGGGCAATGATCGGGCGGCGGGCGGCTCCAACGCTGTTGCGGCAGACACGCCCA
CCACGCATGTCGCCGCGTCGCTGTCCGTAAAGGCATCGTCATGA

Upstream 100 bases:

>100_bases
TCGTGCCGGCCATAGCGGCAACAGCAACAGCAGGCAGCACGAGAGGCAGCTCCGACTGCCCGAGCATCTTCACAGTAACC
ATTTTTGCACGGGAAGTTTG

Downstream 100 bases:

>100_bases
ACGCGCCGGCATCCCGTCGCCGTTTCGTCGTGCGGCCGCTGCGGCGCGTCTCGCTGCATGCGTGCGCCTTGACACTCGCA
AGCGCGTGCGCACTCACCGC

Product: RND efflux system membrane fusion protein

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MEGQRPDSSGTTRDPAKTKRARWIAVAVAVAVIALAAQGIWSRHDAHAALERDAEHASQTSVEVVRPQKSTAGLDLVLPG
NVQAFLDTPIYARTNGYLKKWYADIGAKVKNGQLLAEIDTPEVDDQLRAARADLANAEANYALAKSTAARWTEMLKSKSV
SKQETDEKVGDMLAKKATLDAARFNVARLEKTQSFQKVYAPFDGIVTARNVDVGALIDAGSSGGPAKELFHVAQADRLRV
YVNVPQAYAQQVRARQTAFLTLTETPSRHYPGTVARTAGAVDPQQRTMLVEVDVDNRNGDLLPGAYAQVHFELGTGAAPF
TLPGNALLFRPDGVKLATVDAQHKVKLIAVSLGTDFGTRVAIASGLQGDEQVILNPQDSIIDGAPVRIVAAKAGTATGAS
GATGASGSAAGGEGTAGASGAAASRDGAASASGAAAGNDRAAGGSNAVAADTPTTHVAASLSVKASS

Sequences:

>Translated_467_residues
MEGQRPDSSGTTRDPAKTKRARWIAVAVAVAVIALAAQGIWSRHDAHAALERDAEHASQTSVEVVRPQKSTAGLDLVLPG
NVQAFLDTPIYARTNGYLKKWYADIGAKVKNGQLLAEIDTPEVDDQLRAARADLANAEANYALAKSTAARWTEMLKSKSV
SKQETDEKVGDMLAKKATLDAARFNVARLEKTQSFQKVYAPFDGIVTARNVDVGALIDAGSSGGPAKELFHVAQADRLRV
YVNVPQAYAQQVRARQTAFLTLTETPSRHYPGTVARTAGAVDPQQRTMLVEVDVDNRNGDLLPGAYAQVHFELGTGAAPF
TLPGNALLFRPDGVKLATVDAQHKVKLIAVSLGTDFGTRVAIASGLQGDEQVILNPQDSIIDGAPVRIVAAKAGTATGAS
GATGASGSAAGGEGTAGASGAAASRDGAASASGAAAGNDRAAGGSNAVAADTPTTHVAASLSVKASS
>Mature_467_residues
MEGQRPDSSGTTRDPAKTKRARWIAVAVAVAVIALAAQGIWSRHDAHAALERDAEHASQTSVEVVRPQKSTAGLDLVLPG
NVQAFLDTPIYARTNGYLKKWYADIGAKVKNGQLLAEIDTPEVDDQLRAARADLANAEANYALAKSTAARWTEMLKSKSV
SKQETDEKVGDMLAKKATLDAARFNVARLEKTQSFQKVYAPFDGIVTARNVDVGALIDAGSSGGPAKELFHVAQADRLRV
YVNVPQAYAQQVRARQTAFLTLTETPSRHYPGTVARTAGAVDPQQRTMLVEVDVDNRNGDLLPGAYAQVHFELGTGAAPF
TLPGNALLFRPDGVKLATVDAQHKVKLIAVSLGTDFGTRVAIASGLQGDEQVILNPQDSIIDGAPVRIVAAKAGTATGAS
GATGASGSAAGGEGTAGASGAAASRDGAASASGAAAGNDRAAGGSNAVAADTPTTHVAASLSVKASS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=322, Percent_Identity=25.1552795031056, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI87081796, Length=319, Percent_Identity=28.5266457680251, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1789665, Length=382, Percent_Identity=25.130890052356, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789929, Length=364, Percent_Identity=23.9010989010989, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786668, Length=353, Percent_Identity=24.929178470255, Blast_Score=66, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 48296; Mature: 48296

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGQRPDSSGTTRDPAKTKRARWIAVAVAVAVIALAAQGIWSRHDAHAALERDAEHASQT
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
SVEVVRPQKSTAGLDLVLPGNVQAFLDTPIYARTNGYLKKWYADIGAKVKNGQLLAEIDT
CEEEECCCCCCCCEEEEECCCCEEEECCCEEECCCCHHHHHHHHHCCEEECCEEEEEECC
PEVDDQLRAARADLANAEANYALAKSTAARWTEMLKSKSVSKQETDEKVGDMLAKKATLD
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
AARFNVARLEKTQSFQKVYAPFDGIVTARNVDVGALIDAGSSGGPAKELFHVAQADRLRV
HHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEECCCCCCCHHHHHHHHCCCEEEE
YVNVPQAYAQQVRARQTAFLTLTETPSRHYPGTVARTAGAVDPQQRTMLVEVDVDNRNGD
EEECCHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHCCCCCCCCCEEEEEEEECCCCCC
LLPGAYAQVHFELGTGAAPFTLPGNALLFRPDGVKLATVDAQHKVKLIAVSLGTDFGTRV
CCCCCEEEEEEEECCCCCCEECCCCEEEECCCCCEEEEECCCCEEEEEEEEECCCCCCCE
AIASGLQGDEQVILNPQDSIIDGAPVRIVAAKAGTATGASGATGASGSAAGGEGTAGASG
EEECCCCCCCEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AAASRDGAASASGAAAGNDRAAGGSNAVAADTPTTHVAASLSVKASS
CCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCEEEEEEEEEECC
>Mature Secondary Structure
MEGQRPDSSGTTRDPAKTKRARWIAVAVAVAVIALAAQGIWSRHDAHAALERDAEHASQT
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
SVEVVRPQKSTAGLDLVLPGNVQAFLDTPIYARTNGYLKKWYADIGAKVKNGQLLAEIDT
CEEEECCCCCCCCEEEEECCCCEEEECCCEEECCCCHHHHHHHHHCCEEECCEEEEEECC
PEVDDQLRAARADLANAEANYALAKSTAARWTEMLKSKSVSKQETDEKVGDMLAKKATLD
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
AARFNVARLEKTQSFQKVYAPFDGIVTARNVDVGALIDAGSSGGPAKELFHVAQADRLRV
HHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEECCCCCCCHHHHHHHHCCCEEEE
YVNVPQAYAQQVRARQTAFLTLTETPSRHYPGTVARTAGAVDPQQRTMLVEVDVDNRNGD
EEECCHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHCCCCCCCCCEEEEEEEECCCCCC
LLPGAYAQVHFELGTGAAPFTLPGNALLFRPDGVKLATVDAQHKVKLIAVSLGTDFGTRV
CCCCCEEEEEEEECCCCCCEECCCCEEEECCCCCEEEEECCCCEEEEEEEEECCCCCCCE
AIASGLQGDEQVILNPQDSIIDGAPVRIVAAKAGTATGASGATGASGSAAGGEGTAGASG
EEECCCCCCCEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AAASRDGAASASGAAAGNDRAAGGSNAVAADTPTTHVAASLSVKASS
CCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA