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The map label for this gene is queD [H]

Identifier: 91781441

GI number: 91781441

Start: 73010

End: 73456

Strand: Direct

Name: queD [H]

Synonym: Bxe_A4405

Alternate gene names: 91781441

Gene position: 73010-73456 (Clockwise)

Preceding gene: 91781440

Following gene: 91781442

Centisome position: 1.49

GC content: 59.96

Gene sequence:

>447_bases
GTGCTGACGATTACACGAAAACTCGAATTCGACGCGGGTCACCGCATTCCCGATCACCGCAGCCAGTGCCGTAATCTGCA
CGGTCATCGCTATGTGCTCGAAATCACGCTGCAAGGCGATCTGGTCGACACCGAAGGCGCGCCCGACCGCGGCATGGTGA
TGGACTTCGCCGACGTGAAGTCGCTCGCCGTCGAGCATCTGGTCGACAAGTGGGATCATGCGTTTCTGGTCTATGAAGGC
GACACGCAGGTGCGCGGTTTCCTTGAAACGATGGCCGGGCACAAGACGGTCGTGCTCGATCGCATTCCCACCGTCGAAAA
TCTGGCCGCCGTCGCGTTCGGCATTCTCGCGAACGTCTACGATGCCCACTACGGCGTGAATCTCCGTTTGCACAAGCTGC
GTCTGTACGAGACGCCGAATTGCTGGGCCGACGTGATCCGCGACTAG

Upstream 100 bases:

>100_bases
CGAGATCAACACCAGGCTCGCGATCGACTGGTGCAAACGCCATCCGCAATGGCGCCTGTCGATGCAGACCCACAAGTATC
TGAACATTCCCTGATTTGCC

Downstream 100 bases:

>100_bases
ACTCGGCGCCGCCGCATTCCCGCCGCATTCCCGCAGGAAGTCGCGTCGGGTGGCGCGCCAACCCTCGCGTTATTGTCACG
GTATGATCGCTCCGATAACC

Product: putative 6-pyruvoyl tetrahydropterin synthase

Products: NA

Alternate protein names: CPH4 synthase; Queuosine biosynthesis protein queD [H]

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MLTITRKLEFDAGHRIPDHRSQCRNLHGHRYVLEITLQGDLVDTEGAPDRGMVMDFADVKSLAVEHLVDKWDHAFLVYEG
DTQVRGFLETMAGHKTVVLDRIPTVENLAAVAFGILANVYDAHYGVNLRLHKLRLYETPNCWADVIRD

Sequences:

>Translated_148_residues
MLTITRKLEFDAGHRIPDHRSQCRNLHGHRYVLEITLQGDLVDTEGAPDRGMVMDFADVKSLAVEHLVDKWDHAFLVYEG
DTQVRGFLETMAGHKTVVLDRIPTVENLAAVAFGILANVYDAHYGVNLRLHKLRLYETPNCWADVIRD
>Mature_148_residues
MLTITRKLEFDAGHRIPDHRSQCRNLHGHRYVLEITLQGDLVDTEGAPDRGMVMDFADVKSLAVEHLVDKWDHAFLVYEG
DTQVRGFLETMAGHKTVVLDRIPTVENLAAVAFGILANVYDAHYGVNLRLHKLRLYETPNCWADVIRD

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde [H]

COG id: COG0720

COG function: function code H; 6-pyruvoyl-tetrahydropterin synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTPS family. QueD subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007115 [H]

Pfam domain/function: PF01242 PTPS [H]

EC number: NA

Molecular weight: Translated: 16851; Mature: 16851

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTITRKLEFDAGHRIPDHRSQCRNLHGHRYVLEITLQGDLVDTEGAPDRGMVMDFADVK
CEEEEEEEECCCCCCCCCHHHHHHCCCCCEEEEEEEEECCEECCCCCCCCCEEEEHHHHH
SLAVEHLVDKWDHAFLVYEGDTQVRGFLETMAGHKTVVLDRIPTVENLAAVAFGILANVY
HHHHHHHHHCCCCEEEEEECCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHH
DAHYGVNLRLHKLRLYETPNCWADVIRD
HHCCCCEEEEEEEEEECCCCHHHHHHCC
>Mature Secondary Structure
MLTITRKLEFDAGHRIPDHRSQCRNLHGHRYVLEITLQGDLVDTEGAPDRGMVMDFADVK
CEEEEEEEECCCCCCCCCHHHHHHCCCCCEEEEEEEEECCEECCCCCCCCCEEEEHHHHH
SLAVEHLVDKWDHAFLVYEGDTQVRGFLETMAGHKTVVLDRIPTVENLAAVAFGILANVY
HHHHHHHHHCCCCEEEEEECCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHH
DAHYGVNLRLHKLRLYETPNCWADVIRD
HHCCCCEEEEEEEEEECCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]