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The map label for this gene is fmt [H]

Identifier: 91781431

GI number: 91781431

Start: 62833

End: 63819

Strand: Direct

Name: fmt [H]

Synonym: Bxe_A4415

Alternate gene names: 91781431

Gene position: 62833-63819 (Clockwise)

Preceding gene: 91781430

Following gene: 91781432

Centisome position: 1.28

GC content: 67.88

Gene sequence:

>987_bases
ATGAGTCATTCGTTGCGCGTCATCTTTGCCGGTACGCCGGAGTTCGCCGCGGCCGCACTGGCCGCGATCCACGGTGCAGG
TTTTCCGGTGCCGCTCGTGCTCACCCAGCCGGACCGGCCCGCCGGGCGCGGCATGAAACTGCAGGCGAGCCCGGTCAAGC
GCTATGCGCAGGAACATGGGCTCGCCGTCGCCCAGCCGCCTTCGCTGCGTCGCGCCGGCAAGTATCCTGAGCAAGCCGCC
GCCGCGATCGGGCAACTGCGCGCCACGCCGCACGACGTCATGGTGGTGGCTGCTTACGGTCTGATCCTGCCGCAGGAAGT
GCTCGATATTCCGCCGCTCGGCTGCATCAACATTCACGCGTCGTTATTGCCGCGCTGGCGTGGCGCGGCGCCGATCCATC
GTGCGATCGAAGCGGGCGACGCCGAAACCGGCATCACGCTGATGCAGATGGACGTTGGTCTCGACACCGGCGCCATGATC
TCCGAAACACGCACGGCGATTTCCGGCGACGACACCACGGCCACGCTGCACGACCGTCTCGCGCAAGACGGCGCGAAGCT
GATCGTCGAGGCGCTGGTCGAACTGGAGCGCACCGGCAGGCTGGCGGCAACGCCCCAACCTGCGGAAGGCGTCACCTACG
CGGAAAAGATCGGCAAGCACGAAGCCGCGCTCGACTGGCGCCGCCCGGCGGCCGTGCTCGCGCGCCAGGTGCGTGCGTTC
GACCCGTTCCCCGGCGGCGTCGGCACGCTGGAAGACGGCACGTCGATCAAGATCTGGGCCGCGATTCCCGCCGATACAAA
AGCTGGCGGCGCACCTGGCACGATCGCCGAGGTCACGCCCGAAGGCGTGGTCGTGGCTTGCGGCGAAGGCGCGCTGCGTC
TCACGCAATTGCAGAAACCCGGCGGCAAGCGCCTGCCGGTGCGCGAATTCCTGGCCGGTTCGACGCTGGCCGTGGGACAA
CGCTTTCAACTTCCCGAAGCAAAGTAA

Upstream 100 bases:

>100_bases
GAGTATCTGTCGTCGCTCAAGCAGACGCGCATCAAGAGCAAGATGAAGAAGCTCGCCCACGCAATGTAATGCGCGTTCAC
CTCGCCTACCGCCCCCGTTC

Downstream 100 bases:

>100_bases
CACGCTTGCGCATGGCCTGAACATCGTCCGTTCGGCCGATGTTCGAGCCCCGCTGGACAAGCCGGCCGCGCGTTAGAATC
CTCCCTGCAACATCCCGCAT

Product: methionyl-tRNA formyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MSHSLRVIFAGTPEFAAAALAAIHGAGFPVPLVLTQPDRPAGRGMKLQASPVKRYAQEHGLAVAQPPSLRRAGKYPEQAA
AAIGQLRATPHDVMVVAAYGLILPQEVLDIPPLGCINIHASLLPRWRGAAPIHRAIEAGDAETGITLMQMDVGLDTGAMI
SETRTAISGDDTTATLHDRLAQDGAKLIVEALVELERTGRLAATPQPAEGVTYAEKIGKHEAALDWRRPAAVLARQVRAF
DPFPGGVGTLEDGTSIKIWAAIPADTKAGGAPGTIAEVTPEGVVVACGEGALRLTQLQKPGGKRLPVREFLAGSTLAVGQ
RFQLPEAK

Sequences:

>Translated_328_residues
MSHSLRVIFAGTPEFAAAALAAIHGAGFPVPLVLTQPDRPAGRGMKLQASPVKRYAQEHGLAVAQPPSLRRAGKYPEQAA
AAIGQLRATPHDVMVVAAYGLILPQEVLDIPPLGCINIHASLLPRWRGAAPIHRAIEAGDAETGITLMQMDVGLDTGAMI
SETRTAISGDDTTATLHDRLAQDGAKLIVEALVELERTGRLAATPQPAEGVTYAEKIGKHEAALDWRRPAAVLARQVRAF
DPFPGGVGTLEDGTSIKIWAAIPADTKAGGAPGTIAEVTPEGVVVACGEGALRLTQLQKPGGKRLPVREFLAGSTLAVGQ
RFQLPEAK
>Mature_327_residues
SHSLRVIFAGTPEFAAAALAAIHGAGFPVPLVLTQPDRPAGRGMKLQASPVKRYAQEHGLAVAQPPSLRRAGKYPEQAAA
AIGQLRATPHDVMVVAAYGLILPQEVLDIPPLGCINIHASLLPRWRGAAPIHRAIEAGDAETGITLMQMDVGLDTGAMIS
ETRTAISGDDTTATLHDRLAQDGAKLIVEALVELERTGRLAATPQPAEGVTYAEKIGKHEAALDWRRPAAVLARQVRAFD
PFPGGVGTLEDGTSIKIWAAIPADTKAGGAPGTIAEVTPEGVVVACGEGALRLTQLQKPGGKRLPVREFLAGSTLAVGQR
FQLPEAK

Specific function: Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by:(I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-

COG id: COG0223

COG function: function code J; Methionyl-tRNA formyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fmt family [H]

Homologues:

Organism=Homo sapiens, GI238814322, Length=330, Percent_Identity=28.1818181818182, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI21614513, Length=243, Percent_Identity=29.6296296296296, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI164663775, Length=310, Percent_Identity=30, Blast_Score=99, Evalue=5e-21,
Organism=Escherichia coli, GI1789683, Length=311, Percent_Identity=51.1254019292604, Blast_Score=288, Evalue=2e-79,
Organism=Escherichia coli, GI1788589, Length=297, Percent_Identity=29.96632996633, Blast_Score=128, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI133930964, Length=332, Percent_Identity=25.3012048192771, Blast_Score=91, Evalue=9e-19,
Organism=Saccharomyces cerevisiae, GI6319458, Length=163, Percent_Identity=29.4478527607362, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI45550868, Length=316, Percent_Identity=27.8481012658228, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI28571984, Length=228, Percent_Identity=31.5789473684211, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24585660, Length=258, Percent_Identity=27.1317829457364, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005794
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR001555
- InterPro:   IPR015518 [H]

Pfam domain/function: PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: =2.1.2.9 [H]

Molecular weight: Translated: 34346; Mature: 34215

Theoretical pI: Translated: 7.74; Mature: 7.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHSLRVIFAGTPEFAAAALAAIHGAGFPVPLVLTQPDRPAGRGMKLQASPVKRYAQEHG
CCCCEEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEECHHHHHHHHHCC
LAVAQPPSLRRAGKYPEQAAAAIGQLRATPHDVMVVAAYGLILPQEVLDIPPLGCINIHA
CEEECCCCHHHCCCCHHHHHHHHHHHCCCCHHEEHHHHHHHHCCHHHHCCCCCCEEEHHH
SLLPRWRGAAPIHRAIEAGDAETGITLMQMDVGLDTGAMISETRTAISGDDTTATLHDRL
HHCCCCCCCCHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCCHHHHHHHH
AQDGAKLIVEALVELERTGRLAATPQPAEGVTYAEKIGKHEAALDWRRPAAVLARQVRAF
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCHHHHHCCCCHHHHHHHHHHHC
DPFPGGVGTLEDGTSIKIWAAIPADTKAGGAPGTIAEVTPEGVVVACGEGALRLTQLQKP
CCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCEEEECCCCEEEEECCCCEEEEEECCC
GGKRLPVREFLAGSTLAVGQRFQLPEAK
CCCCCCHHHHHCCCCHHCCCCCCCCCCC
>Mature Secondary Structure 
SHSLRVIFAGTPEFAAAALAAIHGAGFPVPLVLTQPDRPAGRGMKLQASPVKRYAQEHG
CCCEEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEECHHHHHHHHHCC
LAVAQPPSLRRAGKYPEQAAAAIGQLRATPHDVMVVAAYGLILPQEVLDIPPLGCINIHA
CEEECCCCHHHCCCCHHHHHHHHHHHCCCCHHEEHHHHHHHHCCHHHHCCCCCCEEEHHH
SLLPRWRGAAPIHRAIEAGDAETGITLMQMDVGLDTGAMISETRTAISGDDTTATLHDRL
HHCCCCCCCCHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCCHHHHHHHH
AQDGAKLIVEALVELERTGRLAATPQPAEGVTYAEKIGKHEAALDWRRPAAVLARQVRAF
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCHHHHHCCCCHHHHHHHHHHHC
DPFPGGVGTLEDGTSIKIWAAIPADTKAGGAPGTIAEVTPEGVVVACGEGALRLTQLQKP
CCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCEEEECCCCEEEEECCCCEEEEEECCC
GGKRLPVREFLAGSTLAVGQRFQLPEAK
CCCCCCHHHHHCCCCHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA