| Definition | Escherichia coli UTI89 chromosome, complete genome. |
|---|---|
| Accession | NC_007946 |
| Length | 5,065,741 |
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The map label for this gene is tnaA [H]
Identifier: 91213233
GI number: 91213233
Start: 4150282
End: 4151712
Strand: Direct
Name: tnaA [H]
Synonym: UTI89_C4261
Alternate gene names: 91213233
Gene position: 4150282-4151712 (Clockwise)
Preceding gene: 91213232
Following gene: 91213234
Centisome position: 81.93
GC content: 50.45
Gene sequence:
>1431_bases ATGAAGGATTATGTAATGGAAAACTTTAAACATCTCCCTGAACCGTTCCGCATTCGTGTTATTGAGCCAGTAAAACGTAC CACTCGCGCTTATCGTGAAGAGGCAATTATTAAATCCGGTATGAACCCGTTCTTGCTGGATAGCGAAGATGTGTTTATCG ATTTACTGACCGACAGCGGCACCGGGGCGGTGACGCAGAGTATGCAGGCCGCGATGATGCGTGGCGACGAAGCCTACAGC GGCAGCCGCAGCTACTACGCGTTAGCCGAGTCAGTGAAAAATATCTTTGGTTATCAATACACTATTCCGACTCACCAGGG CCGTGGTGCAGAGCAAATCTATATTCCGGTACTGATTAAAAAACGCGAGCAGGAAAAAGGCCTGGATCGCAGCAAAATGG TGGCGTTCTCTAACTATTTCTTTGATACCACGCAGGGCCATAGCCAGATTAACGGCTGTACCGTGCGTAACGTCTATATC AAAGAAGCCTTCGATACTGGCGTGCGTTACGACTTTAAAGGCAACTTTGACCTTGAGGGATTAGAACGCGGTATTGAAGA AGTTGGCCCGAATAACGTGCCGTATATCGTTGCAACCATCACCAGTAACTCCGCAGGTGGTCAGCCGGTTTCACTGGCAA ACTTAAAAGCGATGTACAGCATCGCGAAGAAATACGATATTCCGGTGGTCATGGACTCCGCACGCTTTGCCGAAAACGCC TATTTCATCAAGCAGCGTGAAGCAGAATACAAAGACTGGACCATCGAGCAGATCACCCGCGAAACCTACAAATATGCCGA TATGCTGGCGATGTCCGCCAAGAAAGATGCGATGGTGCCGATGGGCGGCCTGCTGTGCATGAAAGACGACAGCTTCTTTG ATGTGTATACCGAATGCAGAACCCTTTGCGTGGTGCAGGAAGGCTTCCCGACATATGGCGGCCTGGAAGGCGGCGCTATG GAGCGTCTGGCGGTAGGTCTGTATGACGGCATGAATCTGGACTGGCTGGCTTATCGTATCGCGCAGGTGCAGTATCTGGT CGATGGTCTGGAAGAGATTGGCGTTGTCTGTCAGCAGGCGGGCGGTCACGCGGCATTCGTTGATGCAGGTAAACTGTTGC CGCATATCCCGGCAGATCAGTTCCCGGCACAGGCGCTGGCCTGCGAGCTGTATAAAGTCGCCGGTATCCGTGCGGTAGAA ATTGGCTCTTTCCTGTTAGGCCGCGATCCGAAAACCGGTAAACAACTGCCATGCCCGGCTGAACTGCTGCGTTTAACCAT TCCGCGCGCAACATATACTCAAACACATATGGACTTCATTATTGAAGCCTTTAAACATGTGAAAGAGAACGCGGCGAATA TTAAAGGGTTAACCTTTACCTACGAACCGAAAGTATTGCGTCACTTCACCGCAAAACTGAAAGAAGTTTAA
Upstream 100 bases:
>100_bases ATTTGCTTGTTTTAGTAAATGATGGTACTTGCATATATATCTGGCGAATTAATGAATATTGCAAATGTAATATTCACAGG GATCACTGTAATTAAAATAA
Downstream 100 bases:
>100_bases TTAAAACACTCAGAGTGGCTATAAGGATGTTAGCCACTCTATTACCCTACATCCTCAATAACAAAAATAGCCTTCCTCTA AAGGTGGCATCATGACTGAT
Product: tryptophanase
Products: NA
Alternate protein names: L-tryptophan indole-lyase; TNase [H]
Number of amino acids: Translated: 476; Mature: 476
Protein sequence:
>476_residues MKDYVMENFKHLPEPFRIRVIEPVKRTTRAYREEAIIKSGMNPFLLDSEDVFIDLLTDSGTGAVTQSMQAAMMRGDEAYS GSRSYYALAESVKNIFGYQYTIPTHQGRGAEQIYIPVLIKKREQEKGLDRSKMVAFSNYFFDTTQGHSQINGCTVRNVYI KEAFDTGVRYDFKGNFDLEGLERGIEEVGPNNVPYIVATITSNSAGGQPVSLANLKAMYSIAKKYDIPVVMDSARFAENA YFIKQREAEYKDWTIEQITRETYKYADMLAMSAKKDAMVPMGGLLCMKDDSFFDVYTECRTLCVVQEGFPTYGGLEGGAM ERLAVGLYDGMNLDWLAYRIAQVQYLVDGLEEIGVVCQQAGGHAAFVDAGKLLPHIPADQFPAQALACELYKVAGIRAVE IGSFLLGRDPKTGKQLPCPAELLRLTIPRATYTQTHMDFIIEAFKHVKENAANIKGLTFTYEPKVLRHFTAKLKEV
Sequences:
>Translated_476_residues MKDYVMENFKHLPEPFRIRVIEPVKRTTRAYREEAIIKSGMNPFLLDSEDVFIDLLTDSGTGAVTQSMQAAMMRGDEAYS GSRSYYALAESVKNIFGYQYTIPTHQGRGAEQIYIPVLIKKREQEKGLDRSKMVAFSNYFFDTTQGHSQINGCTVRNVYI KEAFDTGVRYDFKGNFDLEGLERGIEEVGPNNVPYIVATITSNSAGGQPVSLANLKAMYSIAKKYDIPVVMDSARFAENA YFIKQREAEYKDWTIEQITRETYKYADMLAMSAKKDAMVPMGGLLCMKDDSFFDVYTECRTLCVVQEGFPTYGGLEGGAM ERLAVGLYDGMNLDWLAYRIAQVQYLVDGLEEIGVVCQQAGGHAAFVDAGKLLPHIPADQFPAQALACELYKVAGIRAVE IGSFLLGRDPKTGKQLPCPAELLRLTIPRATYTQTHMDFIIEAFKHVKENAANIKGLTFTYEPKVLRHFTAKLKEV >Mature_476_residues MKDYVMENFKHLPEPFRIRVIEPVKRTTRAYREEAIIKSGMNPFLLDSEDVFIDLLTDSGTGAVTQSMQAAMMRGDEAYS GSRSYYALAESVKNIFGYQYTIPTHQGRGAEQIYIPVLIKKREQEKGLDRSKMVAFSNYFFDTTQGHSQINGCTVRNVYI KEAFDTGVRYDFKGNFDLEGLERGIEEVGPNNVPYIVATITSNSAGGQPVSLANLKAMYSIAKKYDIPVVMDSARFAENA YFIKQREAEYKDWTIEQITRETYKYADMLAMSAKKDAMVPMGGLLCMKDDSFFDVYTECRTLCVVQEGFPTYGGLEGGAM ERLAVGLYDGMNLDWLAYRIAQVQYLVDGLEEIGVVCQQAGGHAAFVDAGKLLPHIPADQFPAQALACELYKVAGIRAVE IGSFLLGRDPKTGKQLPCPAELLRLTIPRATYTQTHMDFIIEAFKHVKENAANIKGLTFTYEPKVLRHFTAKLKEV
Specific function: Tryptophan catabolism. [C]
COG id: COG3033
COG function: function code E; Tryptophanase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the beta-eliminating lyase family [H]
Homologues:
Organism=Escherichia coli, GI87082323, Length=471, Percent_Identity=100, Blast_Score=982, Evalue=0.0,
Paralogues:
None
Copy number: 7160 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 460 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001597 - InterPro: IPR015424 - InterPro: IPR015421 - InterPro: IPR015422 - InterPro: IPR011166 - InterPro: IPR013440 - InterPro: IPR018176 [H]
Pfam domain/function: PF01212 Beta_elim_lyase [H]
EC number: =4.1.99.1 [H]
Molecular weight: Translated: 53411; Mature: 53411
Theoretical pI: Translated: 6.14; Mature: 6.14
Prosite motif: PS00853 BETA_ELIM_LYASE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.5 %Cys (Translated Protein) 3.6 %Met (Translated Protein) 5.0 %Cys+Met (Translated Protein) 1.5 %Cys (Mature Protein) 3.6 %Met (Mature Protein) 5.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKDYVMENFKHLPEPFRIRVIEPVKRTTRAYREEAIIKSGMNPFLLDSEDVFIDLLTDSG CCCHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEEEEEECCC TGAVTQSMQAAMMRGDEAYSGSRSYYALAESVKNIFGYQYTIPTHQGRGAEQIYIPVLIK CCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCEEEECCCCCCCCCCEEEEEEEEE KREQEKGLDRSKMVAFSNYFFDTTQGHSQINGCTVRNVYIKEAFDTGVRYDFKGNFDLEG CCHHHCCCCHHHEEEEHHCEEECCCCCCCCCCEEEEEEEEEHHHCCCCEEEECCCCCHHH LERGIEEVGPNNVPYIVATITSNSAGGQPVSLANLKAMYSIAKKYDIPVVMDSARFAENA HHHHHHHHCCCCCCEEEEEEECCCCCCCCEEHHHHHHHHHHHHHCCCCEEECCHHHHCCE YFIKQREAEYKDWTIEQITRETYKYADMLAMSAKKDAMVPMGGLLCMKDDSFFDVYTECR EEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHH TLCVVQEGFPTYGGLEGGAMERLAVGLYDGMNLDWLAYRIAQVQYLVDGLEEIGVVCQQA HEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC GGHAAFVDAGKLLPHIPADQFPAQALACELYKVAGIRAVEIGSFLLGRDPKTGKQLPCPA CCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCEEEEECCHHHCCCCCCCCCCCCCHH ELLRLTIPRATYTQTHMDFIIEAFKHVKENAANIKGLTFTYEPKVLRHFTAKLKEV HHHHEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHCC >Mature Secondary Structure MKDYVMENFKHLPEPFRIRVIEPVKRTTRAYREEAIIKSGMNPFLLDSEDVFIDLLTDSG CCCHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEEEEEECCC TGAVTQSMQAAMMRGDEAYSGSRSYYALAESVKNIFGYQYTIPTHQGRGAEQIYIPVLIK CCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCEEEECCCCCCCCCCEEEEEEEEE KREQEKGLDRSKMVAFSNYFFDTTQGHSQINGCTVRNVYIKEAFDTGVRYDFKGNFDLEG CCHHHCCCCHHHEEEEHHCEEECCCCCCCCCCEEEEEEEEEHHHCCCCEEEECCCCCHHH LERGIEEVGPNNVPYIVATITSNSAGGQPVSLANLKAMYSIAKKYDIPVVMDSARFAENA HHHHHHHHCCCCCCEEEEEEECCCCCCCCEEHHHHHHHHHHHHHCCCCEEECCHHHHCCE YFIKQREAEYKDWTIEQITRETYKYADMLAMSAKKDAMVPMGGLLCMKDDSFFDVYTECR EEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHH TLCVVQEGFPTYGGLEGGAMERLAVGLYDGMNLDWLAYRIAQVQYLVDGLEEIGVVCQQA HEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC GGHAAFVDAGKLLPHIPADQFPAQALACELYKVAGIRAVEIGSFLLGRDPKTGKQLPCPA CCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCEEEEECCHHHCCCCCCCCCCCCCHH ELLRLTIPRATYTQTHMDFIIEAFKHVKENAANIKGLTFTYEPKVLRHFTAKLKEV HHHHEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA