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The map label for this gene is kdgK [H]

Identifier: 91213032

GI number: 91213032

Start: 3945691

End: 3946968

Strand: Direct

Name: kdgK [H]

Synonym: UTI89_C4058

Alternate gene names: 91213032

Gene position: 3945691-3946968 (Clockwise)

Preceding gene: 91213029

Following gene: 91213042

Centisome position: 77.89

GC content: 53.83

Gene sequence:

>1278_bases
TTGATAGATCGGCTGCCAGGTGTAAGCACGCTCACACTGCAACCAAAAACGCCGTTCCTGCAAGCTCTCGATGCTTGCTT
CAGGGTTGCTTATTCGCTGGATAACCTGCCTTATCATCAAAGATGTCCTGTGTTTAAAAGTGATGCTGCCCGGACTCGAC
AAAGATTATCGGCGCGCAAGGGCAGAACTTTACCGCCTGGCCGGGGTAAATTTCCCCACTCCACAACGGAATCTTTCAGG
AATACGTTCTGGCTCAAAAAAATAATGGAACACTGTTTTAATATGGTTGACCAGCAAACCACCACAGCGCAAACTAACGC
TAATTTTTTACAGATCAGGTTCACGACTATGTCCAAAAAGATTGCCGTGATTGGCGAATGCATGATTGAGCTTTCCGAGA
AAGGCGCGGACGTTAAGCGCGGTTTCGGCGGCGATACCCTGAACACTTCCGTCTATATCGCCCGTCAGGTCGATCCTGCG
GCATTAACCGTTCATTACGTAACGGCGCTGGGAACGGACAGTTTTAGCCAGCAGATGCTGGACGCCTGGCGCGGCGAGAA
CGTTGATACTTCCCTGACCCAACGGATGGAAAACCGTCTGCCGGGCCTTTACTACATTGAAACCGACAGCACCGGCGAAC
GTACGTTCTACTACTGGCGTAACGAAGCCGCCGCCAAATTCTGGCTGGAGAGTGAGCAATCCGCGGCGATTTGCGAAGAG
CTGGCGAATTTCGATTATCTCTACCTGAGCGGGATTAGCCTGGCGATCTTAAGCCCGACCAGCCGCGAAAAGCTGCTTTC
CCTGCTGCGCGAATGCCGCGCCAACGGCGGAAAAGTGATTTTCGACAATAACTATCGTCCGCGCCTGTGGGCCAGCAAAG
AAGAGACACAGCAGGTGTACCAACAAATGCTGGAATGCACGGATATCGCCTTCCTGACGCTGGACGATGAAGACGCGCTG
TGGGGTCAACAGCCGGTGGAAGACGTCATTGCGCGCACCCATAACGCGGGCGTGAAAGAAGTGGTGGTGAAACGCGGGGC
GGATTCTTGCCTGGTGTCCATTGCTGGCGAAGGGTTAGTGGATGTTCCGGCGGTAAAACTGCCGAAAGAAAAAGTGATCG
ATACCACCGCAGCTGGCGACTCTTTCAGTGCCGGTTATCTGGCGGTACGTTTGACGGGCGGAATTGCGGAAGACGCAGCG
AAACGCGGGCACCTGACCGCAAGTACCGTTATTCAGTATCGCGGCGCGATTATCCCGCGTGAAGCGATGCCAGCGTAA

Upstream 100 bases:

>100_bases
TGATTTCAGTAAAATAGCGATCCGGCGGCAGGCGTTGCGAAGGGTTCAAGGGATGCGTGACCACCGTTAATAGCTCCACG
GCCATTAACCGCCCGCATGT

Downstream 100 bases:

>100_bases
AAGCAGCATATGCAAAAGGCTGGATAGAGTGTTACCCCTCTATCCAGCTCATCCATAAATACCTGATGGTTGTGCTAACT
CATCACCATCAGGCATTACT

Product: 2-dehydro-3-deoxygluconokinase

Products: NA

Alternate protein names: 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase [H]

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MIDRLPGVSTLTLQPKTPFLQALDACFRVAYSLDNLPYHQRCPVFKSDAARTRQRLSARKGRTLPPGRGKFPHSTTESFR
NTFWLKKIMEHCFNMVDQQTTTAQTNANFLQIRFTTMSKKIAVIGECMIELSEKGADVKRGFGGDTLNTSVYIARQVDPA
ALTVHYVTALGTDSFSQQMLDAWRGENVDTSLTQRMENRLPGLYYIETDSTGERTFYYWRNEAAAKFWLESEQSAAICEE
LANFDYLYLSGISLAILSPTSREKLLSLLRECRANGGKVIFDNNYRPRLWASKEETQQVYQQMLECTDIAFLTLDDEDAL
WGQQPVEDVIARTHNAGVKEVVVKRGADSCLVSIAGEGLVDVPAVKLPKEKVIDTTAAGDSFSAGYLAVRLTGGIAEDAA
KRGHLTASTVIQYRGAIIPREAMPA

Sequences:

>Translated_425_residues
MIDRLPGVSTLTLQPKTPFLQALDACFRVAYSLDNLPYHQRCPVFKSDAARTRQRLSARKGRTLPPGRGKFPHSTTESFR
NTFWLKKIMEHCFNMVDQQTTTAQTNANFLQIRFTTMSKKIAVIGECMIELSEKGADVKRGFGGDTLNTSVYIARQVDPA
ALTVHYVTALGTDSFSQQMLDAWRGENVDTSLTQRMENRLPGLYYIETDSTGERTFYYWRNEAAAKFWLESEQSAAICEE
LANFDYLYLSGISLAILSPTSREKLLSLLRECRANGGKVIFDNNYRPRLWASKEETQQVYQQMLECTDIAFLTLDDEDAL
WGQQPVEDVIARTHNAGVKEVVVKRGADSCLVSIAGEGLVDVPAVKLPKEKVIDTTAAGDSFSAGYLAVRLTGGIAEDAA
KRGHLTASTVIQYRGAIIPREAMPA
>Mature_425_residues
MIDRLPGVSTLTLQPKTPFLQALDACFRVAYSLDNLPYHQRCPVFKSDAARTRQRLSARKGRTLPPGRGKFPHSTTESFR
NTFWLKKIMEHCFNMVDQQTTTAQTNANFLQIRFTTMSKKIAVIGECMIELSEKGADVKRGFGGDTLNTSVYIARQVDPA
ALTVHYVTALGTDSFSQQMLDAWRGENVDTSLTQRMENRLPGLYYIETDSTGERTFYYWRNEAAAKFWLESEQSAAICEE
LANFDYLYLSGISLAILSPTSREKLLSLLRECRANGGKVIFDNNYRPRLWASKEETQQVYQQMLECTDIAFLTLDDEDAL
WGQQPVEDVIARTHNAGVKEVVVKRGADSCLVSIAGEGLVDVPAVKLPKEKVIDTTAAGDSFSAGYLAVRLTGGIAEDAA
KRGHLTASTVIQYRGAIIPREAMPA

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI87082281, Length=309, Percent_Identity=99.3527508090615, Blast_Score=634, Evalue=0.0,
Organism=Escherichia coli, GI87081971, Length=276, Percent_Identity=28.2608695652174, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.45 [H]

Molecular weight: Translated: 47368; Mature: 47368

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDRLPGVSTLTLQPKTPFLQALDACFRVAYSLDNLPYHQRCPVFKSDAARTRQRLSARK
CCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCHHHHHHHHHHHHC
GRTLPPGRGKFPHSTTESFRNTFWLKKIMEHCFNMVDQQTTTAQTNANFLQIRFTTMSKK
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEHHHH
IAVIGECMIELSEKGADVKRGFGGDTLNTSVYIARQVDPAALTVHYVTALGTDSFSQQML
HHHHHHHHHHHHHCCCHHHCCCCCCCCCCEEEEEEECCCHHEEEEEHHHHCCCHHHHHHH
DAWRGENVDTSLTQRMENRLPGLYYIETDSTGERTFYYWRNEAAAKFWLESEQSAAICEE
HHHCCCCCCHHHHHHHHHCCCCEEEEECCCCCCEEEEEEECCCHHHHHHCCCCHHHHHHH
LANFDYLYLSGISLAILSPTSREKLLSLLRECRANGGKVIFDNNYRPRLWASKEETQQVY
HCCCCEEEECCCEEEEECCCCHHHHHHHHHHHHCCCCEEEECCCCCCCEECCHHHHHHHH
QQMLECTDIAFLTLDDEDALWGQQPVEDVIARTHNAGVKEVVVKRGADSCLVSIAGEGLV
HHHHHHCCEEEEEECCCCCCCCCCCHHHHHHHHCCCCHHHHHHHCCCCCEEEEECCCCCE
DVPAVKLPKEKVIDTTAAGDSFSAGYLAVRLTGGIAEDAAKRGHLTASTVIQYRGAIIPR
ECCCCCCCHHHHHCCCCCCCCCCCCEEEEEEECCHHHHHHHCCCCHHHHHHHHCCCCCCH
EAMPA
HCCCC
>Mature Secondary Structure
MIDRLPGVSTLTLQPKTPFLQALDACFRVAYSLDNLPYHQRCPVFKSDAARTRQRLSARK
CCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCHHHHHHHHHHHHC
GRTLPPGRGKFPHSTTESFRNTFWLKKIMEHCFNMVDQQTTTAQTNANFLQIRFTTMSKK
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEHHHH
IAVIGECMIELSEKGADVKRGFGGDTLNTSVYIARQVDPAALTVHYVTALGTDSFSQQML
HHHHHHHHHHHHHCCCHHHCCCCCCCCCCEEEEEEECCCHHEEEEEHHHHCCCHHHHHHH
DAWRGENVDTSLTQRMENRLPGLYYIETDSTGERTFYYWRNEAAAKFWLESEQSAAICEE
HHHCCCCCCHHHHHHHHHCCCCEEEEECCCCCCEEEEEEECCCHHHHHHCCCCHHHHHHH
LANFDYLYLSGISLAILSPTSREKLLSLLRECRANGGKVIFDNNYRPRLWASKEETQQVY
HCCCCEEEECCCEEEEECCCCHHHHHHHHHHHHCCCCEEEECCCCCCCEECCHHHHHHHH
QQMLECTDIAFLTLDDEDALWGQQPVEDVIARTHNAGVKEVVVKRGADSCLVSIAGEGLV
HHHHHHCCEEEEEECCCCCCCCCCCHHHHHHHHCCCCHHHHHHHCCCCCEEEEECCCCCE
DVPAVKLPKEKVIDTTAAGDSFSAGYLAVRLTGGIAEDAAKRGHLTASTVIQYRGAIIPR
ECCCCCCCHHHHHCCCCCCCCCCCCEEEEEEECCHHHHHHHCCCCHHHHHHHHCCCCCCH
EAMPA
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503 [H]