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The map label for this gene is mngR [H]

Identifier: 91212973

GI number: 91212973

Start: 3885668

End: 3886423

Strand: Direct

Name: mngR [H]

Synonym: UTI89_C3999

Alternate gene names: 91212973

Gene position: 3885668-3886423 (Clockwise)

Preceding gene: 91212972

Following gene: 91212974

Centisome position: 76.7

GC content: 43.65

Gene sequence:

>756_bases
GTGCGCGCCATGAAATCATTGAGTAAGTCGTCACAAATACCGCTCTATCAACAAGCGGTGGAGTGGATAAGAGAAAGTAT
TTATACCGGGGATCTGGTGGAAGACGATCGCATTCCTTCGGAATACCAGATTATGGATATGCTGGAAGTGAGCCGGGGAA
CCGTTAAAAAAGCGGTCGCCCAACTGGTAAAAGAAGGCGTGTTGATACAGGTCCAGGGGAAGGGAACATTTGTCAAAAAA
GAGAACGTGGCATATCCGTTAGGTGAAGGATTATTGTCATTCGCGGAATCGCTGGAAAGCCAGAAAATACATTTTACCAC
TGAAGTTATTACGTCACGGATTGAACCGGCTAATCGTTATGTGGCAGAGAAATTAAGAATAACGCCCGGTCAGGATATTC
TTTACCTTGAGCGTTTACGTTCAATTGGTGATGAAAAAGCGATGCTGATAGAGAACCGTATCAATATTGAGCTATGCCCC
GGCATCGTGGAAATCGATTTTAATCAACACAATTTATTTCCAACAATAGAAAGTTTGTCGCAAAGAAAAATTCGTTACTC
GGAAAGTCGCTATGCCGCGCGATTAATTGGTAATGAACGCGGTCATTTTTTAGATATCAGTGAAGATGCACCCGTTTTGC
ATCTGGAGCAGTTAGTCTTTTTCTCCCGAGGATTACCCGTTGAGTTTGGCAACGTCTGGTTAAAAGGAAATAAATACTAT
CTTGGCACCGTGCTGCAACGGCGGGAAGTGAGTTAA

Upstream 100 bases:

>100_bases
CCCCTAAAATGTGAGACGCTTCGATCCTCTTTTTCGCCTGTTCACCTACTATACGCTTGAAGTTGTCCATGATTGTCCAT
AGACAACTGTAAATGTTCAG

Downstream 100 bases:

>100_bases
GTACACTTTTTTAAGAGGAATAAAATGCAAGGCATACAGTTTCAGGAAAATTTTATTCAACGACTTCCGGCAGGGTTAAG
CGTTGAACAGATCATCCATC

Product: putative regulator

Products: NA

Alternate protein names: Fatty acyl-responsive regulator; Protein P30 [H]

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MRAMKSLSKSSQIPLYQQAVEWIRESIYTGDLVEDDRIPSEYQIMDMLEVSRGTVKKAVAQLVKEGVLIQVQGKGTFVKK
ENVAYPLGEGLLSFAESLESQKIHFTTEVITSRIEPANRYVAEKLRITPGQDILYLERLRSIGDEKAMLIENRINIELCP
GIVEIDFNQHNLFPTIESLSQRKIRYSESRYAARLIGNERGHFLDISEDAPVLHLEQLVFFSRGLPVEFGNVWLKGNKYY
LGTVLQRREVS

Sequences:

>Translated_251_residues
MRAMKSLSKSSQIPLYQQAVEWIRESIYTGDLVEDDRIPSEYQIMDMLEVSRGTVKKAVAQLVKEGVLIQVQGKGTFVKK
ENVAYPLGEGLLSFAESLESQKIHFTTEVITSRIEPANRYVAEKLRITPGQDILYLERLRSIGDEKAMLIENRINIELCP
GIVEIDFNQHNLFPTIESLSQRKIRYSESRYAARLIGNERGHFLDISEDAPVLHLEQLVFFSRGLPVEFGNVWLKGNKYY
LGTVLQRREVS
>Mature_251_residues
MRAMKSLSKSSQIPLYQQAVEWIRESIYTGDLVEDDRIPSEYQIMDMLEVSRGTVKKAVAQLVKEGVLIQVQGKGTFVKK
ENVAYPLGEGLLSFAESLESQKIHFTTEVITSRIEPANRYVAEKLRITPGQDILYLERLRSIGDEKAMLIENRINIELCP
GIVEIDFNQHNLFPTIESLSQRKIRYSESRYAARLIGNERGHFLDISEDAPVLHLEQLVFFSRGLPVEFGNVWLKGNKYY
LGTVLQRREVS

Specific function: Represses mngA and mngB. Regulates its own expression [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786950, Length=235, Percent_Identity=28.5106382978723, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1790540, Length=184, Percent_Identity=29.3478260869565, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1788418, Length=231, Percent_Identity=24.2424242424242, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1790118, Length=144, Percent_Identity=26.3888888888889, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 28736; Mature: 28736

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAMKSLSKSSQIPLYQQAVEWIRESIYTGDLVEDDRIPSEYQIMDMLEVSRGTVKKAVA
CCHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
QLVKEGVLIQVQGKGTFVKKENVAYPLGEGLLSFAESLESQKIHFTTEVITSRIEPANRY
HHHHCCEEEEEECCCEEEECCCCCCCHHHHHHHHHHHHCCCEEEEHHHHHHHHCCHHHHH
VAEKLRITPGQDILYLERLRSIGDEKAMLIENRINIELCPGIVEIDFNQHNLFPTIESLS
HHHHHCCCCCCCHHHHHHHHHCCCCCEEEEECCCCEEECCCEEEEECCCCCCCCCHHHHH
QRKIRYSESRYAARLIGNERGHFLDISEDAPVLHLEQLVFFSRGLPVEFGNVWLKGNKYY
HHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHCCCCEEECCEEEECCCEE
LGTVLQRREVS
EHHHHHHHCCC
>Mature Secondary Structure
MRAMKSLSKSSQIPLYQQAVEWIRESIYTGDLVEDDRIPSEYQIMDMLEVSRGTVKKAVA
CCHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
QLVKEGVLIQVQGKGTFVKKENVAYPLGEGLLSFAESLESQKIHFTTEVITSRIEPANRY
HHHHCCEEEEEECCCEEEECCCCCCCHHHHHHHHHHHHCCCEEEEHHHHHHHHCCHHHHH
VAEKLRITPGQDILYLERLRSIGDEKAMLIENRINIELCPGIVEIDFNQHNLFPTIESLS
HHHHHCCCCCCCHHHHHHHHHCCCCCEEEEECCCCEEECCCEEEEECCCCCCCCCHHHHH
QRKIRYSESRYAARLIGNERGHFLDISEDAPVLHLEQLVFFSRGLPVEFGNVWLKGNKYY
HHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHCCCCEEECCEEEECCCEE
LGTVLQRREVS
EHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2548486; 9278503; 9063979; 8905232; 7805834 [H]