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The map label for this gene is degQ [H]

Identifier: 91212654

GI number: 91212654

Start: 3590368

End: 3591777

Strand: Direct

Name: degQ [H]

Synonym: UTI89_C3665

Alternate gene names: 91212654

Gene position: 3590368-3591777 (Clockwise)

Preceding gene: 91212653

Following gene: 91212655

Centisome position: 70.88

GC content: 51.77

Gene sequence:

>1410_bases
TTGAATCTCTTTTCTTATCATTCAGGTACGAGAGCAGGAATAATGAAAAAACAAACCCAGCTGTTGAGTGCATTAGCGTT
AAGTGTCGGGTTAACTCTCTCGGCGTCATTTCAGGCCGTCGCGTCGATTCCAGGCCAGGTTGCCGATCAGGCCCCCCTCC
CCAGTCTGGCTCCAATGCTGGAAAAAGTGCTTCCGGCAGTGGTGAGCGTACGGGTGGAAGGAACGGCCAGTCAGGGACAG
AAAATCCCGGAAGAATTCAAAAAGTTTTTTGGTGATGATTTACCGGATCAACCTGCACAACCCTTCGAAGGTTTAGGCTC
CGGTGTCATCATCAACGCCAATAAAGGCTATGTGCTGACCAACAACCATGTGATTAATCAGGCACAGAAAATCAGTATTC
AGCTCAATGATGGGCGCGAGTTTGATGCAAAACTGATTGGTAGCGATGACCAGAGCGATATCGCCCTGTTGCAAATTCAA
AACCCGAGCAAATTAACGCAAATCGCTATTGCCGACTCCGATAAATTGCGCGTCGGTGATTTTGCCGTGGCGGTCGGTAA
CCCATTTGGCCTTGGGCAAACCGCCACCTCTGGCATTATATCCGCATTAGGCCGCAGCGGGTTGAATCTTGAAGGTCTGG
AAAACTTTATCCAGACAGATGCTTCCATTAACCGCGGTAACTCCGGCGGTGCACTGTTAAACCTTAACGGTGAGTTAATT
GGCATCAACACTGCAATCCTTGCGCCTGGCGGCGGTAGCGTCGGGATTGGATTTGCCATTCCCAGTAATATGGCGCGAAC
ACTGGCGCAGCAGCTTATCGACTTTGGAGAAATCAAACGCGGCCTGTTAGGCATCAAAGGCACCGAGATGAGTGCCGATA
TCGCCAAGGCCTTCAACCTTGACGTGCAGCGTGGCGCGTTTGTCAGCGAAGTGTTGCCAGGTTCTGGCTCGGCGAAAGCG
GGCGTCAAAGCGGGCGATATTATTACCAGCCTCAACGGCAAACCGCTGAATAGCTTTGCTGAGTTGCGCTCTCGTATCGC
GACCACCGAGCCGGGCACAAAAGTGAAGCTTGGCCTGCTGCGTAACGGCAAACCACTGGAAGTAGAAGTGACGCTCGATA
CCAGCACCTCTTCGTCGGCCAGCGCTGAAATGATCACGCCAGCGCTGGAAGGTGCAACGTTGAGCGATGGTCAGCTAAAA
GATGGTGGCAAAGGTATTAAGATCGATGAGGTTGTCAAAGGAAGCCCAGCTGCTCAGGCTGGCTTGCAAAAAGACGATGT
GATCATTGGCGTCAACCGCGATCGGGTGAACTCGATTGCTGAAATGCGTAAAGTGCTGGCGGCAAAACCGGCCATCATTG
CCCTGCAAATTGTACGCGGCAATGAAAGCCTCTACCTACTAATGCGTTAA

Upstream 100 bases:

>100_bases
GGCGCAGCCATTGCGCCCTCCTCTTCTCTCCCTCCCCGACTATCATTTAATCTGGTGTCTCATTGTTAGCCGTCTGAAAA
TTCAATAACATCAAACTGTT

Downstream 100 bases:

>100_bases
TGTCGTAAACCGGGCATCAGGCTGACGTGTGATGTCCGGTTAACTCGTGGTATGCTGCTGCCGTTCCCTTTTTTAACGAT
GCCTCCATCATGTTTGTGAA

Product: serine endoprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 469; Mature: 469

Protein sequence:

>469_residues
MNLFSYHSGTRAGIMKKQTQLLSALALSVGLTLSASFQAVASIPGQVADQAPLPSLAPMLEKVLPAVVSVRVEGTASQGQ
KIPEEFKKFFGDDLPDQPAQPFEGLGSGVIINANKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQ
NPSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIISALGRSGLNLEGLENFIQTDASINRGNSGGALLNLNGELI
GINTAILAPGGGSVGIGFAIPSNMARTLAQQLIDFGEIKRGLLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKA
GVKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDTSTSSSASAEMITPALEGATLSDGQLK
DGGKGIKIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSIAEMRKVLAAKPAIIALQIVRGNESLYLLMR

Sequences:

>Translated_469_residues
MNLFSYHSGTRAGIMKKQTQLLSALALSVGLTLSASFQAVASIPGQVADQAPLPSLAPMLEKVLPAVVSVRVEGTASQGQ
KIPEEFKKFFGDDLPDQPAQPFEGLGSGVIINANKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQ
NPSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIISALGRSGLNLEGLENFIQTDASINRGNSGGALLNLNGELI
GINTAILAPGGGSVGIGFAIPSNMARTLAQQLIDFGEIKRGLLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKA
GVKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDTSTSSSASAEMITPALEGATLSDGQLK
DGGKGIKIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSIAEMRKVLAAKPAIIALQIVRGNESLYLLMR
>Mature_469_residues
MNLFSYHSGTRAGIMKKQTQLLSALALSVGLTLSASFQAVASIPGQVADQAPLPSLAPMLEKVLPAVVSVRVEGTASQGQ
KIPEEFKKFFGDDLPDQPAQPFEGLGSGVIINANKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQ
NPSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIISALGRSGLNLEGLENFIQTDASINRGNSGGALLNLNGELI
GINTAILAPGGGSVGIGFAIPSNMARTLAQQLIDFGEIKRGLLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKA
GVKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDTSTSSSASAEMITPALEGATLSDGQLK
DGGKGIKIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSIAEMRKVLAAKPAIIALQIVRGNESLYLLMR

Specific function: Protease with a shared specificity with degP [H]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI22129776, Length=316, Percent_Identity=36.0759493670886, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI4506141, Length=294, Percent_Identity=35.3741496598639, Blast_Score=158, Evalue=1e-38,
Organism=Homo sapiens, GI24308541, Length=305, Percent_Identity=30.4918032786885, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI7019477, Length=296, Percent_Identity=33.445945945946, Blast_Score=132, Evalue=5e-31,
Organism=Escherichia coli, GI1789629, Length=455, Percent_Identity=99.3406593406593, Blast_Score=887, Evalue=0.0,
Organism=Escherichia coli, GI1786356, Length=440, Percent_Identity=57.5, Blast_Score=504, Evalue=1e-144,
Organism=Escherichia coli, GI1789630, Length=271, Percent_Identity=45.0184501845018, Blast_Score=211, Evalue=1e-55,
Organism=Drosophila melanogaster, GI24646839, Length=289, Percent_Identity=33.2179930795848, Blast_Score=129, Evalue=5e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.-

Molecular weight: Translated: 48783; Mature: 48783

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLFSYHSGTRAGIMKKQTQLLSALALSVGLTLSASFQAVASIPGQVADQAPLPSLAPML
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEECCHHHHHHCCCHHCCCCCCCHHHHHH
EKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQPAQPFEGLGSGVIINANKGYVLT
HHHHHHHEEEEEECCHHCCCCCHHHHHHHHCCCCCCCCCCCHHHCCCCEEEECCCCEEEE
NNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQNPSKLTQIAIADSDKLRVGD
CCCEECCEEEEEEEECCCCCCCEEEECCCCCCCEEEEEECCCCCEEEEEEECCCCEEECE
FAVAVGNPFGLGQTATSGIISALGRSGLNLEGLENFIQTDASINRGNSGGALLNLNGELI
EEEEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCEEE
GINTAILAPGGGSVGIGFAIPSNMARTLAQQLIDFGEIKRGLLGIKGTEMSADIAKAFNL
EEEEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCC
DVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGLL
CCCCCCHHHHHCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEEEE
RNGKPLEVEVTLDTSTSSSASAEMITPALEGATLSDGQLKDGGKGIKIDEVVKGSPAAQA
CCCCEEEEEEEEECCCCCCCCHHHCCHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCHHHC
GLQKDDVIIGVNRDRVNSIAEMRKVLAAKPAIIALQIVRGNESLYLLMR
CCCCCCEEEECCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEEC
>Mature Secondary Structure
MNLFSYHSGTRAGIMKKQTQLLSALALSVGLTLSASFQAVASIPGQVADQAPLPSLAPML
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEECCHHHHHHCCCHHCCCCCCCHHHHHH
EKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQPAQPFEGLGSGVIINANKGYVLT
HHHHHHHEEEEEECCHHCCCCCHHHHHHHHCCCCCCCCCCCHHHCCCCEEEECCCCEEEE
NNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQNPSKLTQIAIADSDKLRVGD
CCCEECCEEEEEEEECCCCCCCEEEECCCCCCCEEEEEECCCCCEEEEEEECCCCEEECE
FAVAVGNPFGLGQTATSGIISALGRSGLNLEGLENFIQTDASINRGNSGGALLNLNGELI
EEEEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCEEE
GINTAILAPGGGSVGIGFAIPSNMARTLAQQLIDFGEIKRGLLGIKGTEMSADIAKAFNL
EEEEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCC
DVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGLL
CCCCCCHHHHHCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEEEE
RNGKPLEVEVTLDTSTSSSASAEMITPALEGATLSDGQLKDGGKGIKIDEVVKGSPAAQA
CCCCEEEEEEEEECCCCCCCCHHHCCHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCHHHC
GLQKDDVIIGVNRDRVNSIAEMRKVLAAKPAIIALQIVRGNESLYLLMR
CCCCCCEEEECCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8576051; 9278503 [H]