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The map label for this gene is fucR [H]

Identifier: 91212174

GI number: 91212174

Start: 3093864

End: 3094604

Strand: Direct

Name: fucR [H]

Synonym: UTI89_C3177

Alternate gene names: 91212174

Gene position: 3093864-3094604 (Clockwise)

Preceding gene: 91212173

Following gene: 91212178

Centisome position: 61.07

GC content: 47.91

Gene sequence:

>741_bases
GTGAAAAATATGAAAGCGGCACGCCAGCAAGCGATAGTCGACCTGCTGCTGAACCATACCAGCCTGACCACGGAAGCTCT
CTCTGAACAGCTAAAGGTCAGTAAAGAAACCATTCGTCGCGATCTCAATGAATTACAGACGCAGGGTAAAATTCTGCGCA
ATCATGGGCGCGCTAAATATATCCACCGTCAAAATCAAGACAGTGGCGATCCCTTTCACATCCGGCTGAAAAGCCATTAT
GCGCATAAAGCAGATATCGCGCGCGAGGCGCTCGCGTGGATTGAAGAAGGGATGGTGATAGCCTTAGACGCCAGTTCAAC
CTGCTGGTATCTGGCACGCCAGTTGCCTGACATCAACATCCAGGTCTTCACCAATAGCCATCCGATTTGCCATGAACTCG
GTAAACGCGAACGCATTAAACTGATCAGTTCCGGCGGCACACTTGAGCGCAAATATGGCTGTTACGTCAATCCCTCGCTG
ATTTCCCAACTTAAATCGCTGGAAATCGATCTGTTTATTTTTTCTTGTGAAGGGATCGATAGCAGCGGCGCACTGTGGGA
CTCCAATGCCATCAACGCTGATTACAAATCAATGTTATTAAAACGTGCCGCGCAATCGTTGTTATTGATTGATAAAAGTA
AATTTAATCGTTCAGGGGAAGCCCGCATCGGGCATCTGGATGAGGTAACGCACATTATTTCTGATGAGCGCCAGGTTACA
ACTTCTTTGGTAACAGCCTGA

Upstream 100 bases:

>100_bases
CGAACGAGCGAAGTACGGGAATATTCTTTTAAAAAAAGGGGTAACACCGTAATCTCATACCGGTACGCCCGCATGACGCG
GGCGGTTATCGAATGATGGG

Downstream 100 bases:

>100_bases
CGGAAAGGGTAGCAGGCCGGAGACGACGCCCCGGCCTTACCTGTTATCGCTCGTCGCGACGACCACCCACCGCAGCCCAG
ATACGGCGGACGTGCACCGT

Product: DNA-binding transcriptional activator FucR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MKNMKAARQQAIVDLLLNHTSLTTEALSEQLKVSKETIRRDLNELQTQGKILRNHGRAKYIHRQNQDSGDPFHIRLKSHY
AHKADIAREALAWIEEGMVIALDASSTCWYLARQLPDINIQVFTNSHPICHELGKRERIKLISSGGTLERKYGCYVNPSL
ISQLKSLEIDLFIFSCEGIDSSGALWDSNAINADYKSMLLKRAAQSLLLIDKSKFNRSGEARIGHLDEVTHIISDERQVT
TSLVTA

Sequences:

>Translated_246_residues
MKNMKAARQQAIVDLLLNHTSLTTEALSEQLKVSKETIRRDLNELQTQGKILRNHGRAKYIHRQNQDSGDPFHIRLKSHY
AHKADIAREALAWIEEGMVIALDASSTCWYLARQLPDINIQVFTNSHPICHELGKRERIKLISSGGTLERKYGCYVNPSL
ISQLKSLEIDLFIFSCEGIDSSGALWDSNAINADYKSMLLKRAAQSLLLIDKSKFNRSGEARIGHLDEVTHIISDERQVT
TSLVTA
>Mature_246_residues
MKNMKAARQQAIVDLLLNHTSLTTEALSEQLKVSKETIRRDLNELQTQGKILRNHGRAKYIHRQNQDSGDPFHIRLKSHY
AHKADIAREALAWIEEGMVIALDASSTCWYLARQLPDINIQVFTNSHPICHELGKRERIKLISSGGTLERKYGCYVNPSL
ISQLKSLEIDLFIFSCEGIDSSGALWDSNAINADYKSMLLKRAAQSLLLIDKSKFNRSGEARIGHLDEVTHIISDERQVT
TSLVTA

Specific function: Transcriptional activator of the fuc operon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789170, Length=243, Percent_Identity=99.1769547325103, Blast_Score=498, Evalue=1e-142,
Organism=Escherichia coli, GI1788069, Length=231, Percent_Identity=33.3333333333333, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1789829, Length=232, Percent_Identity=28.448275862069, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI87082344, Length=230, Percent_Identity=28.695652173913, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787540, Length=233, Percent_Identity=25.3218884120172, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1790753, Length=236, Percent_Identity=23.3050847457627, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1789059, Length=231, Percent_Identity=27.2727272727273, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790635, Length=231, Percent_Identity=23.8095238095238, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789519, Length=232, Percent_Identity=27.1551724137931, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI226510968, Length=238, Percent_Identity=26.0504201680672, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27766; Mature: 27766

Theoretical pI: Translated: 8.62; Mature: 8.62

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNMKAARQQAIVDLLLNHTSLTTEALSEQLKVSKETIRRDLNELQTQGKILRNHGRAKY
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
IHRQNQDSGDPFHIRLKSHYAHKADIAREALAWIEEGMVIALDASSTCWYLARQLPDINI
HCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHCCCCEE
QVFTNSHPICHELGKRERIKLISSGGTLERKYGCYVNPSLISQLKSLEIDLFIFSCEGID
EEEECCCCHHHHCCCHHEEEEEECCCCEEECCCCEECHHHHHHHHHCEEEEEEEEECCCC
SSGALWDSNAINADYKSMLLKRAAQSLLLIDKSKFNRSGEARIGHLDEVTHIISDERQVT
CCCCEECCCCCCHHHHHHHHHHHHHHHEEEEHHHCCCCCCCCCCHHHHHHHHHCCCHHHH
TSLVTA
HHHHCC
>Mature Secondary Structure
MKNMKAARQQAIVDLLLNHTSLTTEALSEQLKVSKETIRRDLNELQTQGKILRNHGRAKY
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
IHRQNQDSGDPFHIRLKSHYAHKADIAREALAWIEEGMVIALDASSTCWYLARQLPDINI
HCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHCCCCEE
QVFTNSHPICHELGKRERIKLISSGGTLERKYGCYVNPSLISQLKSLEIDLFIFSCEGID
EEEECCCCHHHHCCCHHEEEEEECCCCEEECCCCEECHHHHHHHHHCEEEEEEEEECCCC
SSGALWDSNAINADYKSMLLKRAAQSLLLIDKSKFNRSGEARIGHLDEVTHIISDERQVT
CCCCEECCCCCCHHHHHHHHHHHHHHHEEEEHHHCCCCCCCCCCHHHHHHHHHCCCHHHH
TSLVTA
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2664711; 9278503 [H]