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The map label for this gene is fucP [H]

Identifier: 91212170

GI number: 91212170

Start: 3088740

End: 3090056

Strand: Direct

Name: fucP [H]

Synonym: UTI89_C3173

Alternate gene names: 91212170

Gene position: 3088740-3090056 (Clockwise)

Preceding gene: 91212169

Following gene: 91212171

Centisome position: 60.97

GC content: 47.68

Gene sequence:

>1317_bases
ATGGGAAACACATCAATACAAACGCAGAGTTACCGTGCGGTAGATAAAGATGCAGGGCAAAGCAGAAGTTACATTATTCC
ATTCGCGCTGCTGTGCTCACTGTTTTTTCTTTGGGCGGTAGCCAATAACCTTAACGACATTTTATTGCCTCAATTCCAGC
AGGCTTTTACGCTGACAAATTTCCAGGCTGGCCTGATCCAATCGGCCTTTTACTTTGGTTATTTCATTATCCCAATCCCT
GCCGGGATATTGATGAAAAAACTCAGTTATAAAGCAGGGATTATTACCGGATTGTTTTTATATGCCTTCGGCGCTGCATT
ATTCTGGCCCGCCGCAGAAATAATGAACTACACCTTGTTTTTAGTTGGCCTATTTATTATTGCAGCCGGATTAGGTTGTC
TGGAAACTGCCGCAAACCCTTTTGTTACGGTATTAGGGCCGGAAAGCAGTGGTCACTTCCGCTTAAATCTTGCGCAAACA
TTTAACTCATTTGGCGCAATTATCGCGGTTGTCTTTGGGCAAAGTCTTATTTTGTCTAACGTGCCACATCAATCGCAAGA
CGTTCTCGATAAAATGTCTCCAGAGCAATTGAGTGCGTATAAACACAGCCTGGTATTATCGGTACAGACACCTTATATGA
TCATCGTGGCTATCGTGTTACTGGTCGCCCTGCTGATCATGCTGACGAAATTCCCGGCATTGCAGAGTGATAATCACAGT
GACGCCAAACAAGGATCGTTCTCCGCATCGCTTTCTCGCCTGGCGCGTATTCGCCACTGGCGCTGGGCAGTATTAGCGCA
ATTCTGCTACGTCGGCGCACAAACAGCCTGCTGGAGCTATTTGATTCGCTACGCTGTAGAAGAAATTCCAGGTATGACAG
CAGGTTTTGCCGCTAACTATTTAACCGGAACCATGGTGTGCTTCTTTATTGGTCGTTTCACCGGTACCTGGCTCATCAGT
CGCTTCGCACCACACAAAGTCCTGGCAGCCTACGCATTAATCGCTATGGCACTGTGCCTGATCTCAGCCTTCGCTGGCGG
TCATGTGGGTTTAATAGCCCTGACTTTATGCAGTGCCTTTATGTCGATTCAGTACCCAACAATCTTCTCGCTGGGCATTA
AGAATCTCGGCCAGGACACCAAATACGGTTCGTCCTTCATCGTTATGACCATTATTGGCGGCGGTATTGTCACTCCGGTC
ATGGGGTTTGTCAGTGACGCAGCGGGCAACATCCCCACTGCCGAACTGCTCCCGGCACTCTGCTTCGCAGTCATCTTTAT
CTTTGCCCGTTTCCGTTCTCAAACGGCAACTAACTGA

Upstream 100 bases:

>100_bases
CAGGCAAATATTCACTGATATGAAGCCCGAACTCGCTGGTTTTGCACTTTTGAAAACATAACCGATTACGTGCTTAAGCT
TCTGAACCTAAGAGGATGCT

Downstream 100 bases:

>100_bases
ACATATTTTCCGAATAAAGTGAGGAATCAGTAATGAAAAAAATCAGCTTACCGAAAATTGGTATCCGCCCGGTTATTGAC
GGTCGTCGCATGGGTGTTCG

Product: L-fucose transporter

Products: Proton [Cytoplasm]; L-fucose [Cytoplasm] [C]

Alternate protein names: 6-deoxy-L-galactose permease; L-fucose permease [H]

Number of amino acids: Translated: 438; Mature: 437

Protein sequence:

>438_residues
MGNTSIQTQSYRAVDKDAGQSRSYIIPFALLCSLFFLWAVANNLNDILLPQFQQAFTLTNFQAGLIQSAFYFGYFIIPIP
AGILMKKLSYKAGIITGLFLYAFGAALFWPAAEIMNYTLFLVGLFIIAAGLGCLETAANPFVTVLGPESSGHFRLNLAQT
FNSFGAIIAVVFGQSLILSNVPHQSQDVLDKMSPEQLSAYKHSLVLSVQTPYMIIVAIVLLVALLIMLTKFPALQSDNHS
DAKQGSFSASLSRLARIRHWRWAVLAQFCYVGAQTACWSYLIRYAVEEIPGMTAGFAANYLTGTMVCFFIGRFTGTWLIS
RFAPHKVLAAYALIAMALCLISAFAGGHVGLIALTLCSAFMSIQYPTIFSLGIKNLGQDTKYGSSFIVMTIIGGGIVTPV
MGFVSDAAGNIPTAELLPALCFAVIFIFARFRSQTATN

Sequences:

>Translated_438_residues
MGNTSIQTQSYRAVDKDAGQSRSYIIPFALLCSLFFLWAVANNLNDILLPQFQQAFTLTNFQAGLIQSAFYFGYFIIPIP
AGILMKKLSYKAGIITGLFLYAFGAALFWPAAEIMNYTLFLVGLFIIAAGLGCLETAANPFVTVLGPESSGHFRLNLAQT
FNSFGAIIAVVFGQSLILSNVPHQSQDVLDKMSPEQLSAYKHSLVLSVQTPYMIIVAIVLLVALLIMLTKFPALQSDNHS
DAKQGSFSASLSRLARIRHWRWAVLAQFCYVGAQTACWSYLIRYAVEEIPGMTAGFAANYLTGTMVCFFIGRFTGTWLIS
RFAPHKVLAAYALIAMALCLISAFAGGHVGLIALTLCSAFMSIQYPTIFSLGIKNLGQDTKYGSSFIVMTIIGGGIVTPV
MGFVSDAAGNIPTAELLPALCFAVIFIFARFRSQTATN
>Mature_437_residues
GNTSIQTQSYRAVDKDAGQSRSYIIPFALLCSLFFLWAVANNLNDILLPQFQQAFTLTNFQAGLIQSAFYFGYFIIPIPA
GILMKKLSYKAGIITGLFLYAFGAALFWPAAEIMNYTLFLVGLFIIAAGLGCLETAANPFVTVLGPESSGHFRLNLAQTF
NSFGAIIAVVFGQSLILSNVPHQSQDVLDKMSPEQLSAYKHSLVLSVQTPYMIIVAIVLLVALLIMLTKFPALQSDNHSD
AKQGSFSASLSRLARIRHWRWAVLAQFCYVGAQTACWSYLIRYAVEEIPGMTAGFAANYLTGTMVCFFIGRFTGTWLISR
FAPHKVLAAYALIAMALCLISAFAGGHVGLIALTLCSAFMSIQYPTIFSLGIKNLGQDTKYGSSFIVMTIIGGGIVTPVM
GFVSDAAGNIPTAELLPALCFAVIFIFARFRSQTATN

Specific function: Mediates the uptake of L-fucose across the boundary membrane with the concomitant transport of protons into the cell (symport system). Can also transport L-galactose and D-arabinose, but at reduced rates compared with L-fucose. Is not able to transport L-

COG id: COG0738

COG function: function code G; Fucose permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family [H]

Homologues:

Organism=Escherichia coli, GI1789166, Length=438, Percent_Identity=99.5433789954338, Blast_Score=884, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005275
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47579; Mature: 47448

Theoretical pI: Translated: 8.83; Mature: 8.83

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GNTSIQTQSYRAVDKDAGQSRSYIIPFALLCSLFFLWAVANNLNDILLPQFQQAFTLTN
CCCCCCCHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
FQAGLIQSAFYFGYFIIPIPAGILMKKLSYKAGIITGLFLYAFGAALFWPAAEIMNYTLF
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVGLFIIAAGLGCLETAANPFVTVLGPESSGHFRLNLAQTFNSFGAIIAVVFGQSLILSN
HHHHHHHHHCCHHHHHCCCCEEEEECCCCCCCEEEEHHHHHHHHHHHHHHHHCCHHHHCC
VPHQSQDVLDKMSPEQLSAYKHSLVLSVQTPYMIIVAIVLLVALLIMLTKFPALQSDNHS
CCCCHHHHHHCCCHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
DAKQGSFSASLSRLARIRHWRWAVLAQFCYVGAQTACWSYLIRYAVEEIPGMTAGFAANY
CHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHH
LTGTMVCFFIGRFTGTWLISRFAPHKVLAAYALIAMALCLISAFAGGHVGLIALTLCSAF
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
MSIQYPTIFSLGIKNLGQDTKYGSSFIVMTIIGGGIVTPVMGFVSDAAGNIPTAELLPAL
HHCCCCHHHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHH
CFAVIFIFARFRSQTATN
HHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-fucose [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-fucose [Periplasm] = Proton [Cytoplasm] + L-fucose [Cytoplasm] [C]

General reaction: Permease [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2664711; 9278503; 2553671; 8052131; 2829831; 7783647 [H]