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The map label for this gene is xseA

Identifier: 91211832

GI number: 91211832

Start: 2770056

End: 2771432

Strand: Direct

Name: xseA

Synonym: UTI89_C2827

Alternate gene names: 91211832

Gene position: 2770056-2771432 (Clockwise)

Preceding gene: 91211829

Following gene: 91211844

Centisome position: 54.68

GC content: 54.25

Gene sequence:

>1377_bases
ATGTTACCTTCTCAATCCCCTGCAATTTTTACCGTTAGCCGCCTGAATCAAACGGTTCGTCTGCTGCTTGAGCATGAGAT
GGGGCAGGTGTGGATCAGCGGCGAAATCTCTAATTTTACACAACCAGCCTCCGGTCACTGGTACTTTACGCTTAAAGACG
ATACCGCGCAGGTGCGCTGTGCGATGTTCCGAAACAGCAACCGCCGGGTCACCTTCCGCCCACAGCACGGGCAACAGGTT
TTAGTTCGCGCCAATATTACACTCTACGAGCCGCGCGGCGATTATCAAATTATCGTCGAAAGTATGCAGCCGGCCGGTGA
AGGATTGCTGCAACTGAAGTACGAACAGCTTAAAGCGAAGTTGCAGGCTGAAGGTTTGTTCGATCTGCAATACAAAAAAT
CACTCCCCTCCCCTGCGCATTGCGTTGGTGTGATCACCTCAAAAACCGGTGCTGCGCTACATGATATTTTGCATGTGTTA
AAACGTCGCGATCCTTCTCTGCCGGTGATCATCTACCCCACCGCCGTTCAGGGCGATGACGCGCCAGGGCAAATTGTTCG
CGCCATTGAACTGGCGAATCAGCGCAATGAGTGCGACGTGTTGATCGTTGGGCGCGGCGGCGGTTCGCTGGAAGATTTAT
GGAGTTTTAACGACGAACGTGTAGCGCGGGCGATTTTTGCCAGCCGCATTCCGATAGTCAGCGCCGTCGGGCATGAAACC
GATGTGACGATTGCCGACTTTGTCGCTGATCTGCGTGCGCCAACGCCGTCAGCCGCCGCTGAAGTGGTGAGCCGCAATCA
GCAAGAGTTACTGCGCCAGGTGCAATCGACCCATCAACGGCTGGAGATGGCGATGGATTATTATCTCGCCAACCGCACGC
GTCGTTTTACGCAGATCCATCATCGCTTGCAGCAGCAGCATCCGCAGCTCCGGCTGGCACGTCAGCAAACTATGCTCGAA
CGTCTGCAAAAGCGGATGAGCTTTGCGCTGGAGAGTCAGCTTAAACGCGCGGGTCAGCAACAGCAGCGATTAACACGGCA
ACTCGTCCAGCAAAATCCGCAGTCGCGTATTCATCGCGCGCAAACGCGCATTCAGCAACTGGAATATCGTTTAGCAGAAA
CCCTGCGCGCACAGCTTAGCGCCACGCGTGAACGTTTCGGTAATGCAGTAACACACCTCGAAGCCGTAAGCCCACTGTCA
ACGCTGGCGCGCGGTTATAGCGTCACCAGCGCCGCTGATGGCGCGGTGTTAAAACAGGTTAAGCAAGTGAAAGTGGGTGA
GACACTGACCACACGACTGGGAGATGGTGTGGTGATTAGTGAAGTCAGCGCCGTAACAAAAACCCGCAAATCACGTAAAA
AAACGTCTAATCCGTAG

Upstream 100 bases:

>100_bases
GATTGCATCTACCCCTTTTTGCAAAAAATGCTTGCTATCCCCGGAGGGCGGGTTACTATCGACTGAATAACCTGCTGATT
TAGAATTTGATCTCGCTCAC

Downstream 100 bases:

>100_bases
ACCGGATAAGAGGCGCCAGCATCGCATCCGGCAATAGCTCCCAGGCTACGCCAGATCCGCCATGCTGGTTACTGGAAGCA
GGTCACCAGACCCGGTTTAT

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MLPSQSPAIFTVSRLNQTVRLLLEHEMGQVWISGEISNFTQPASGHWYFTLKDDTAQVRCAMFRNSNRRVTFRPQHGQQV
LVRANITLYEPRGDYQIIVESMQPAGEGLLQLKYEQLKAKLQAEGLFDLQYKKSLPSPAHCVGVITSKTGAALHDILHVL
KRRDPSLPVIIYPTAVQGDDAPGQIVRAIELANQRNECDVLIVGRGGGSLEDLWSFNDERVARAIFASRIPIVSAVGHET
DVTIADFVADLRAPTPSAAAEVVSRNQQELLRQVQSTHQRLEMAMDYYLANRTRRFTQIHHRLQQQHPQLRLARQQTMLE
RLQKRMSFALESQLKRAGQQQQRLTRQLVQQNPQSRIHRAQTRIQQLEYRLAETLRAQLSATRERFGNAVTHLEAVSPLS
TLARGYSVTSAADGAVLKQVKQVKVGETLTTRLGDGVVISEVSAVTKTRKSRKKTSNP

Sequences:

>Translated_458_residues
MLPSQSPAIFTVSRLNQTVRLLLEHEMGQVWISGEISNFTQPASGHWYFTLKDDTAQVRCAMFRNSNRRVTFRPQHGQQV
LVRANITLYEPRGDYQIIVESMQPAGEGLLQLKYEQLKAKLQAEGLFDLQYKKSLPSPAHCVGVITSKTGAALHDILHVL
KRRDPSLPVIIYPTAVQGDDAPGQIVRAIELANQRNECDVLIVGRGGGSLEDLWSFNDERVARAIFASRIPIVSAVGHET
DVTIADFVADLRAPTPSAAAEVVSRNQQELLRQVQSTHQRLEMAMDYYLANRTRRFTQIHHRLQQQHPQLRLARQQTMLE
RLQKRMSFALESQLKRAGQQQQRLTRQLVQQNPQSRIHRAQTRIQQLEYRLAETLRAQLSATRERFGNAVTHLEAVSPLS
TLARGYSVTSAADGAVLKQVKQVKVGETLTTRLGDGVVISEVSAVTKTRKSRKKTSNP
>Mature_458_residues
MLPSQSPAIFTVSRLNQTVRLLLEHEMGQVWISGEISNFTQPASGHWYFTLKDDTAQVRCAMFRNSNRRVTFRPQHGQQV
LVRANITLYEPRGDYQIIVESMQPAGEGLLQLKYEQLKAKLQAEGLFDLQYKKSLPSPAHCVGVITSKTGAALHDILHVL
KRRDPSLPVIIYPTAVQGDDAPGQIVRAIELANQRNECDVLIVGRGGGSLEDLWSFNDERVARAIFASRIPIVSAVGHET
DVTIADFVADLRAPTPSAAAEVVSRNQQELLRQVQSTHQRLEMAMDYYLANRTRRFTQIHHRLQQQHPQLRLARQQTMLE
RLQKRMSFALESQLKRAGQQQQRLTRQLVQQNPQSRIHRAQTRIQQLEYRLAETLRAQLSATRERFGNAVTHLEAVSPLS
TLARGYSVTSAADGAVLKQVKQVKVGETLTTRLGDGVVISEVSAVTKTRKSRKKTSNP

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family

Homologues:

Organism=Escherichia coli, GI1788856, Length=454, Percent_Identity=93.1718061674009, Blast_Score=848, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): EX7L_ECO45 (B7MHZ0)

Other databases:

- EMBL:   CU928161
- RefSeq:   YP_002392346.1
- EnsemblBacteria:   EBESCT00000138371
- GeneID:   7128875
- GenomeReviews:   CU928161_GR
- GeneTree:   EBGT00050000011693
- HOGENOM:   HBG634411
- OMA:   EISNFTR
- ProtClustDB:   PRK00286
- BioCyc:   ECOL585035:ECS88_2681-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00378
- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365
- TIGRFAMs:   TIGR00237

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti

EC number: =3.1.11.6

Molecular weight: Translated: 51555; Mature: 51555

Theoretical pI: Translated: 10.62; Mature: 10.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPSQSPAIFTVSRLNQTVRLLLEHEMGQVWISGEISNFTQPASGHWYFTLKDDTAQVRC
CCCCCCCCEEEHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEEEEECCCHHHHH
AMFRNSNRRVTFRPQHGQQVLVRANITLYEPRGDYQIIVESMQPAGEGLLQLKYEQLKAK
HHHCCCCCEEEECCCCCCEEEEEEEEEEECCCCCCEEHEEHHCCCCCHHHHHHHHHHHHH
LQAEGLFDLQYKKSLPSPAHCVGVITSKTGAALHDILHVLKRRDPSLPVIIYPTAVQGDD
HHHCCCEEEHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCC
APGQIVRAIELANQRNECDVLIVGRGGGSLEDLWSFNDERVARAIFASRIPIVSAVGHET
CHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHCCCHHHHHHHHHHHCCCHHEECCCCC
DVTIADFVADLRAPTPSAAAEVVSRNQQELLRQVQSTHQRLEMAMDYYLANRTRRFTQIH
CCHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HRLQQQHPQLRLARQQTMLERLQKRMSFALESQLKRAGQQQQRLTRQLVQQNPQSRIHRA
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
QTRIQQLEYRLAETLRAQLSATRERFGNAVTHLEAVSPLSTLARGYSVTSAADGAVLKQV
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
KQVKVGETLTTRLGDGVVISEVSAVTKTRKSRKKTSNP
HHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLPSQSPAIFTVSRLNQTVRLLLEHEMGQVWISGEISNFTQPASGHWYFTLKDDTAQVRC
CCCCCCCCEEEHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEEEEECCCHHHHH
AMFRNSNRRVTFRPQHGQQVLVRANITLYEPRGDYQIIVESMQPAGEGLLQLKYEQLKAK
HHHCCCCCEEEECCCCCCEEEEEEEEEEECCCCCCEEHEEHHCCCCCHHHHHHHHHHHHH
LQAEGLFDLQYKKSLPSPAHCVGVITSKTGAALHDILHVLKRRDPSLPVIIYPTAVQGDD
HHHCCCEEEHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCC
APGQIVRAIELANQRNECDVLIVGRGGGSLEDLWSFNDERVARAIFASRIPIVSAVGHET
CHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHCCCHHHHHHHHHHHCCCHHEECCCCC
DVTIADFVADLRAPTPSAAAEVVSRNQQELLRQVQSTHQRLEMAMDYYLANRTRRFTQIH
CCHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HRLQQQHPQLRLARQQTMLERLQKRMSFALESQLKRAGQQQQRLTRQLVQQNPQSRIHRA
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
QTRIQQLEYRLAETLRAQLSATRERFGNAVTHLEAVSPLSTLARGYSVTSAADGAVLKQV
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
KQVKVGETLTTRLGDGVVISEVSAVTKTRKSRKKTSNP
HHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA