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The map label for this gene is atoS [H]

Identifier: 91211513

GI number: 91211513

Start: 2456334

End: 2458172

Strand: Direct

Name: atoS [H]

Synonym: UTI89_C2501

Alternate gene names: 91211513

Gene position: 2456334-2458172 (Clockwise)

Preceding gene: 91211511

Following gene: 91211514

Centisome position: 48.49

GC content: 48.83

Gene sequence:

>1839_bases
GTGGATTTCAGCATGCATTATATGAAGTGGATTTATCCACGCCGCTTACGCAATCAAATGATCCTGATGGCAATCCTGAT
GGTCATTGTCCCAACGCTTACTATTGGTTATATCGTAGAAACGGAAGGACGTTCAGCAGTCTTATCTGAAAAAGAGAAAA
AACTTTCTGCCGTGGTCAACCTGCTTAATCAGGCGCTAGGCAATCGCTACGATCTCTACATCGACTTACCGCGTGAGGAG
CGTATCCGCGCATTAAATGCAGAACTTGCCCCCATTACCGAAAATATCACTCACGCCTTCCCTGGCATCGGCGCTGGTTA
TTACAACAAAACGCTGGATGCGATAATCACCTACGCGCCTTCAGCGCTATATCAGAATAATGTGGGCGTTACCATTGCCG
CAGATCACCCTGGTCGCGAAGTCATGCGTACAAATACCCCTTTGGTTTATTCAGGCAGGCAGGTGCGCGGCGATATTTTG
AATTCAATGATTCCCATTGAGCGTAATGGTGAAATCCTCGGCTATATCTGGGCCAATGAATTAACCGAAGATATTCGCCG
CCAGGCCTGGAAAATGGATGTGAGGATTATCATTGTGCTCACCGCCGGTTTGCTGATAAGCCTGCTGTTGATTGTCCTTT
TCTCCCGTCGCCTGAGCGCCAATATAGATATCATCACCGATGGCCTCTCGACTCTGGCTCAAAATATTCCCACTCGATTA
CCACAATTGCCCGGTGAAATGGGGCAAATCAGTCAGAGTGTTAACAACCTCGCCCAGGCACTGCGTGAAACGCGAACACT
TAACGATCTGATTATTGAAAACGCTGCCGATGGCGTCATTGCCATTGACCGCCAGGGTGATGTAACCACCATGAACCCAG
CAGCAGAAGTCATCACTGGCTATCAACGTCATGAACTGGTAGGGCAGCCTTACTCCATGTTGTTCGACAATACTCAGTTC
TACAGTCCAGTACTGGATACGCTGGAACATGGCACCGAACATGTAGCACTGGAGATCAGTTTTCCAGGCCGTGACCGCAC
CATTGAACTCAGTGTCACGACCAGTCGTATTCATAACACGCACGGTGAAATGATAGGTGCTTTGGTGATTTTCTCTGATT
TAACTGCCCGCAAAGAAACCCAGCGCCGCATGGCGCAAGCAGAACGCCTCGCCACACTGGGTGAGCTGATGGCTGGCGTG
GCGCATGAAGTACGTAATCCGCTAACAGCTATTCGTGGTTATGTACAGATCTTGCGCCAACAAACCCGTGACCCAATACA
TCAGGAATATCTGTCCGTAGTACTCAAAGAAATCGATTCAATTAACAAAGTTATTCAGCAATTGCTCGAATTTTCACGTC
CACGCCACAGTCAATGGCAACAAGTCAGCCTCAATGCATTGGTTGAAGAAACTCTGGTACTGGTACAAACCGCCGGCGTA
CAAGCGCGGGTCGACTTCATAAGCGAACTGGATAATGAATTAAGCCCGATTAACGCCGATCGTGAACTGCTCAAACAGGT
ACTACTGAATATCCTGATCAATGCCGTCCAGGCTATCAGTGCACGAGGGAAAATTCGCATTCGAACCTGGCAGTATAGCG
ACTCGCAACAGGCCATTTCGATAGAGGACAACGGCAGTGGCATTGATCTCTCGCTGCAAAAAAAGATCTTCGATCCCTTT
TTCACTACCAAAGCCTCAGGAACCGGGCTTGGTCTGGCGTTAAGTCAACGCATCATTAATGCCCATCAGGGTGATATTCG
CGTCGCCAGTTTGCCGGGCTACGGCGCAACCTTCACGCTTATTTTACCGATCAACCCGCAGGGAAATCAGACTGTATGA

Upstream 100 bases:

>100_bases
AAGCGTGTTACCGCAATGTTCTCTCTTCTCTGGAATATGATACACCGCCGAGAAATCATCACCTTAACCTCTGATAATCG
TCATATACCGGACAAGACTA

Downstream 100 bases:

>100_bases
CTGCTATTAATCGCATCCTTATTGTGGATGATGAAGATAATGTTCGCCGTATGCTGAGCACCGCTTTTGCACTACAAGGA
TTCGAAACACATTGTGCGAA

Product: sensory histidine kinase AtoS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 612; Mature: 612

Protein sequence:

>612_residues
MDFSMHYMKWIYPRRLRNQMILMAILMVIVPTLTIGYIVETEGRSAVLSEKEKKLSAVVNLLNQALGNRYDLYIDLPREE
RIRALNAELAPITENITHAFPGIGAGYYNKTLDAIITYAPSALYQNNVGVTIAADHPGREVMRTNTPLVYSGRQVRGDIL
NSMIPIERNGEILGYIWANELTEDIRRQAWKMDVRIIIVLTAGLLISLLLIVLFSRRLSANIDIITDGLSTLAQNIPTRL
PQLPGEMGQISQSVNNLAQALRETRTLNDLIIENAADGVIAIDRQGDVTTMNPAAEVITGYQRHELVGQPYSMLFDNTQF
YSPVLDTLEHGTEHVALEISFPGRDRTIELSVTTSRIHNTHGEMIGALVIFSDLTARKETQRRMAQAERLATLGELMAGV
AHEVRNPLTAIRGYVQILRQQTRDPIHQEYLSVVLKEIDSINKVIQQLLEFSRPRHSQWQQVSLNALVEETLVLVQTAGV
QARVDFISELDNELSPINADRELLKQVLLNILINAVQAISARGKIRIRTWQYSDSQQAISIEDNGSGIDLSLQKKIFDPF
FTTKASGTGLGLALSQRIINAHQGDIRVASLPGYGATFTLILPINPQGNQTV

Sequences:

>Translated_612_residues
MDFSMHYMKWIYPRRLRNQMILMAILMVIVPTLTIGYIVETEGRSAVLSEKEKKLSAVVNLLNQALGNRYDLYIDLPREE
RIRALNAELAPITENITHAFPGIGAGYYNKTLDAIITYAPSALYQNNVGVTIAADHPGREVMRTNTPLVYSGRQVRGDIL
NSMIPIERNGEILGYIWANELTEDIRRQAWKMDVRIIIVLTAGLLISLLLIVLFSRRLSANIDIITDGLSTLAQNIPTRL
PQLPGEMGQISQSVNNLAQALRETRTLNDLIIENAADGVIAIDRQGDVTTMNPAAEVITGYQRHELVGQPYSMLFDNTQF
YSPVLDTLEHGTEHVALEISFPGRDRTIELSVTTSRIHNTHGEMIGALVIFSDLTARKETQRRMAQAERLATLGELMAGV
AHEVRNPLTAIRGYVQILRQQTRDPIHQEYLSVVLKEIDSINKVIQQLLEFSRPRHSQWQQVSLNALVEETLVLVQTAGV
QARVDFISELDNELSPINADRELLKQVLLNILINAVQAISARGKIRIRTWQYSDSQQAISIEDNGSGIDLSLQKKIFDPF
FTTKASGTGLGLALSQRIINAHQGDIRVASLPGYGATFTLILPINPQGNQTV
>Mature_612_residues
MDFSMHYMKWIYPRRLRNQMILMAILMVIVPTLTIGYIVETEGRSAVLSEKEKKLSAVVNLLNQALGNRYDLYIDLPREE
RIRALNAELAPITENITHAFPGIGAGYYNKTLDAIITYAPSALYQNNVGVTIAADHPGREVMRTNTPLVYSGRQVRGDIL
NSMIPIERNGEILGYIWANELTEDIRRQAWKMDVRIIIVLTAGLLISLLLIVLFSRRLSANIDIITDGLSTLAQNIPTRL
PQLPGEMGQISQSVNNLAQALRETRTLNDLIIENAADGVIAIDRQGDVTTMNPAAEVITGYQRHELVGQPYSMLFDNTQF
YSPVLDTLEHGTEHVALEISFPGRDRTIELSVTTSRIHNTHGEMIGALVIFSDLTARKETQRRMAQAERLATLGELMAGV
AHEVRNPLTAIRGYVQILRQQTRDPIHQEYLSVVLKEIDSINKVIQQLLEFSRPRHSQWQQVSLNALVEETLVLVQTAGV
QARVDFISELDNELSPINADRELLKQVLLNILINAVQAISARGKIRIRTWQYSDSQQAISIEDNGSGIDLSLQKKIFDPF
FTTKASGTGLGLALSQRIINAHQGDIRVASLPGYGATFTLILPINPQGNQTV

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=608, Percent_Identity=99.0131578947368, Blast_Score=1220, Evalue=0.0,
Organism=Escherichia coli, GI1790436, Length=242, Percent_Identity=42.1487603305785, Blast_Score=167, Evalue=2e-42,
Organism=Escherichia coli, GI1790300, Length=350, Percent_Identity=29.1428571428571, Blast_Score=125, Evalue=8e-30,
Organism=Escherichia coli, GI145693157, Length=273, Percent_Identity=29.6703296703297, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1786600, Length=365, Percent_Identity=23.8356164383562, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI48994928, Length=422, Percent_Identity=25.5924170616114, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1786912, Length=308, Percent_Identity=26.6233766233766, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1788713, Length=367, Percent_Identity=23.9782016348774, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1789149, Length=247, Percent_Identity=26.3157894736842, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1789808, Length=218, Percent_Identity=27.5229357798165, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI87081816, Length=267, Percent_Identity=27.3408239700375, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1788393, Length=264, Percent_Identity=25.7575757575758, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87082128, Length=260, Percent_Identity=26.5384615384615, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1788279, Length=225, Percent_Identity=25.3333333333333, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1790346, Length=234, Percent_Identity=26.9230769230769, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 68322; Mature: 68322

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFSMHYMKWIYPRRLRNQMILMAILMVIVPTLTIGYIVETEGRSAVLSEKEKKLSAVVN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCHHHHHHHHHHHHHHHH
LLNQALGNRYDLYIDLPREERIRALNAELAPITENITHAFPGIGAGYYNKTLDAIITYAP
HHHHHHCCCEEEEEECCHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC
SALYQNNVGVTIAADHPGREVMRTNTPLVYSGRQVRGDILNSMIPIERNGEILGYIWANE
HHHHCCCCCEEEECCCCCHHHHHCCCCEEECCCHHHHHHHHCCCCCCCCCCEEEEEEHHH
LTEDIRRQAWKMDVRIIIVLTAGLLISLLLIVLFSRRLSANIDIITDGLSTLAQNIPTRL
HHHHHHHHHHHCCHHEEHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHH
PQLPGEMGQISQSVNNLAQALRETRTLNDLIIENAADGVIAIDRQGDVTTMNPAAEVITG
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEECCCHHHHHHC
YQRHELVGQPYSMLFDNTQFYSPVLDTLEHGTEHVALEISFPGRDRTIELSVTTSRIHNT
HHHHHHCCCCHHHHHCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEEEEHHHHHHH
HGEMIGALVIFSDLTARKETQRRMAQAERLATLGELMAGVAHEVRNPLTAIRGYVQILRQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QTRDPIHQEYLSVVLKEIDSINKVIQQLLEFSRPRHSQWQQVSLNALVEETLVLVQTAGV
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
QARVDFISELDNELSPINADRELLKQVLLNILINAVQAISARGKIRIRTWQYSDSQQAIS
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCEEE
IEDNGSGIDLSLQKKIFDPFFTTKASGTGLGLALSQRIINAHQGDIRVASLPGYGATFTL
EECCCCCCEEEHHHHHCCHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCEEEE
ILPINPQGNQTV
EEEECCCCCCCC
>Mature Secondary Structure
MDFSMHYMKWIYPRRLRNQMILMAILMVIVPTLTIGYIVETEGRSAVLSEKEKKLSAVVN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCHHHHHHHHHHHHHHHH
LLNQALGNRYDLYIDLPREERIRALNAELAPITENITHAFPGIGAGYYNKTLDAIITYAP
HHHHHHCCCEEEEEECCHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC
SALYQNNVGVTIAADHPGREVMRTNTPLVYSGRQVRGDILNSMIPIERNGEILGYIWANE
HHHHCCCCCEEEECCCCCHHHHHCCCCEEECCCHHHHHHHHCCCCCCCCCCEEEEEEHHH
LTEDIRRQAWKMDVRIIIVLTAGLLISLLLIVLFSRRLSANIDIITDGLSTLAQNIPTRL
HHHHHHHHHHHCCHHEEHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHH
PQLPGEMGQISQSVNNLAQALRETRTLNDLIIENAADGVIAIDRQGDVTTMNPAAEVITG
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEECCCHHHHHHC
YQRHELVGQPYSMLFDNTQFYSPVLDTLEHGTEHVALEISFPGRDRTIELSVTTSRIHNT
HHHHHHCCCCHHHHHCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEEEEHHHHHHH
HGEMIGALVIFSDLTARKETQRRMAQAERLATLGELMAGVAHEVRNPLTAIRGYVQILRQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QTRDPIHQEYLSVVLKEIDSINKVIQQLLEFSRPRHSQWQQVSLNALVEETLVLVQTAGV
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
QARVDFISELDNELSPINADRELLKQVLLNILINAVQAISARGKIRIRTWQYSDSQQAIS
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCEEE
IEDNGSGIDLSLQKKIFDPFFTTKASGTGLGLALSQRIINAHQGDIRVASLPGYGATFTL
EECCCCCCEEEHHHHHCCHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCEEEE
ILPINPQGNQTV
EEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]