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The map label for this gene is yeiQ [H]

Identifier: 91211462

GI number: 91211462

Start: 2406284

End: 2407759

Strand: Direct

Name: yeiQ [H]

Synonym: UTI89_C2449

Alternate gene names: 91211462

Gene position: 2406284-2407759 (Clockwise)

Preceding gene: 91211461

Following gene: 91211463

Centisome position: 47.5

GC content: 51.49

Gene sequence:

>1476_bases
GTGACTCCTATGAATACAATCGCCTCCGTTACGCTCCCGCATCATGTACACGCTCCACGCTACGATCGACAGCAGTTGCA
ATCACGTATCGTTCATTTTGGCTTTGGAGCCTTTCACCGCGCACATCAGGCATTACTGACCGATCGTGTGCTGAATGCCC
AGGGCGGCGACTGGGGGATCTGTGAAATCAGCTTGTTCAGCGGCGATCAACTGATGAGCCAACTCCGCGCACAGAACCAT
TTATATACCGTGCTGGAGAAAGGTGCGGACGGCAATCAGGCGATAATTGTCGGTGCCGTTCACGAATGTCTGAATGCAAA
ACTGGATTCCTTAGCGGCAATTATTGAGAAATTTTGCGAGCCACAGGTGGCAATTGTTTCCCTGACAATTACCGAAAAAG
GCTATTGTATTGACCCGGCCATCGGTGCACTCGACACCAGCAATCCGCGTATTATTCACGATCTACAAAACCCTGAAGAA
CCTCACTCCGCGCCAGGTATTCTCGTCGAAGCACTGAAACGCCGCCGTGAGCGCGGCCTTACACCGTTTACCGTGCTCTC
CTGCGACAATATTCCCGACAATGGCCATGTGGTGAAAAACGCGGTGCTGGGAATGGCAGAAAAACGTTCGCCAGAACTCG
CCGGGTGGATAAAAGAACACGTCAGTTTTCCGGGAACTATGGTCGACCGCATTGTTCCGGCTGCAACCAACGAATCACTG
GCGGAAATAAGCCAGCATCTGGGGGTGAATGATCCCTGCGCGATTAGCTGCGAACCGTTTATCCAGTGGGTGGTTGAAGA
TAACTTCGTCGCTGGGCGTCCTGCCTGGGAAGTCGCAGGTGTACAAATGGTGAATGATGTCCTGCCATGGGAAGAGATGA
AACTGCGTATGCTTAATGGCAGCCACTCTTTTCTCGCTTATCTGGGTTACCTCTCAGGATTCGCCCATATCAGTGATTGC
ATGCAGGATCGCGCATTTCGCCATGCCGCCAGAACATTAATGCTGGATGAGCAAGCGCCGACACTGCGGATTAAAGATGT
CGATTTAACACAATATGCGGATAAGTTAATTGCACGTTTTGCTAATCCGGCACTGAAACATAAGACCTGGCAAATCGCGA
TGGATGGCAGCCAAAAATTACCGCAACGCATGCTGGCAGGTATTCGCATACATCTGGGGCGCGAAACGGACTGGTCGTTG
CTGGCATTAGGCGTTGCAGGCTGGATGCGTTACGTCAGCGGCGTTGATGATGCCGGAAATGCCATTGATGTTCGCGATCC
GCTTAGCGATAAAATTCGTGAACTTGTTGCGGTCAGCAGCAGTGAACAACGCGTAACCGCCCTGCTTTCCCTGCGTGAAA
TTTTCGGTGATGATCTGCCAGATAACCCGCATTTTGTGCAGGCCATCGAACAAGCCTGGCAACAAATCGCACAATTCGGC
GCGCATCAGGCGCTATTAAACACCCTCAAAATTTAA

Upstream 100 bases:

>100_bases
ATTGATCGCCCTCACACTTCATCGCATTAACAATCCAGACCAATTTCAATTGTTGTCATATAACTTTACACTGTCATTGT
TAATTAATCGTTACTAAGAC

Downstream 100 bases:

>100_bases
CGATTTCTGCGGTTAAAGCGGATGAAGCTCGCCTTCGTCCGCTCTCCCCTTCTCTTTTCTGCCTTTTTTAGCCAGGATTA
ACGCTCAGTTAACTTACCAG

Product: oxidoreductase YeiQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 491; Mature: 490

Protein sequence:

>491_residues
MTPMNTIASVTLPHHVHAPRYDRQQLQSRIVHFGFGAFHRAHQALLTDRVLNAQGGDWGICEISLFSGDQLMSQLRAQNH
LYTVLEKGADGNQAIIVGAVHECLNAKLDSLAAIIEKFCEPQVAIVSLTITEKGYCIDPAIGALDTSNPRIIHDLQNPEE
PHSAPGILVEALKRRRERGLTPFTVLSCDNIPDNGHVVKNAVLGMAEKRSPELAGWIKEHVSFPGTMVDRIVPAATNESL
AEISQHLGVNDPCAISCEPFIQWVVEDNFVAGRPAWEVAGVQMVNDVLPWEEMKLRMLNGSHSFLAYLGYLSGFAHISDC
MQDRAFRHAARTLMLDEQAPTLRIKDVDLTQYADKLIARFANPALKHKTWQIAMDGSQKLPQRMLAGIRIHLGRETDWSL
LALGVAGWMRYVSGVDDAGNAIDVRDPLSDKIRELVAVSSSEQRVTALLSLREIFGDDLPDNPHFVQAIEQAWQQIAQFG
AHQALLNTLKI

Sequences:

>Translated_491_residues
MTPMNTIASVTLPHHVHAPRYDRQQLQSRIVHFGFGAFHRAHQALLTDRVLNAQGGDWGICEISLFSGDQLMSQLRAQNH
LYTVLEKGADGNQAIIVGAVHECLNAKLDSLAAIIEKFCEPQVAIVSLTITEKGYCIDPAIGALDTSNPRIIHDLQNPEE
PHSAPGILVEALKRRRERGLTPFTVLSCDNIPDNGHVVKNAVLGMAEKRSPELAGWIKEHVSFPGTMVDRIVPAATNESL
AEISQHLGVNDPCAISCEPFIQWVVEDNFVAGRPAWEVAGVQMVNDVLPWEEMKLRMLNGSHSFLAYLGYLSGFAHISDC
MQDRAFRHAARTLMLDEQAPTLRIKDVDLTQYADKLIARFANPALKHKTWQIAMDGSQKLPQRMLAGIRIHLGRETDWSL
LALGVAGWMRYVSGVDDAGNAIDVRDPLSDKIRELVAVSSSEQRVTALLSLREIFGDDLPDNPHFVQAIEQAWQQIAQFG
AHQALLNTLKI
>Mature_490_residues
TPMNTIASVTLPHHVHAPRYDRQQLQSRIVHFGFGAFHRAHQALLTDRVLNAQGGDWGICEISLFSGDQLMSQLRAQNHL
YTVLEKGADGNQAIIVGAVHECLNAKLDSLAAIIEKFCEPQVAIVSLTITEKGYCIDPAIGALDTSNPRIIHDLQNPEEP
HSAPGILVEALKRRRERGLTPFTVLSCDNIPDNGHVVKNAVLGMAEKRSPELAGWIKEHVSFPGTMVDRIVPAATNESLA
EISQHLGVNDPCAISCEPFIQWVVEDNFVAGRPAWEVAGVQMVNDVLPWEEMKLRMLNGSHSFLAYLGYLSGFAHISDCM
QDRAFRHAARTLMLDEQAPTLRIKDVDLTQYADKLIARFANPALKHKTWQIAMDGSQKLPQRMLAGIRIHLGRETDWSLL
ALGVAGWMRYVSGVDDAGNAIDVRDPLSDKIRELVAVSSSEQRVTALLSLREIFGDDLPDNPHFVQAIEQAWQQIAQFGA
HQALLNTLKI

Specific function: Unknown

COG id: COG0246

COG function: function code G; Mannitol-1-phosphate/altronate dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannitol dehydrogenase family. UxuB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788497, Length=488, Percent_Identity=97.9508196721311, Blast_Score=991, Evalue=0.0,
Organism=Escherichia coli, GI1790779, Length=485, Percent_Identity=56.701030927835, Blast_Score=558, Evalue=1e-160,
Organism=Escherichia coli, GI1787823, Length=464, Percent_Identity=55.3879310344828, Blast_Score=550, Evalue=1e-157,
Organism=Escherichia coli, GI1790028, Length=232, Percent_Identity=28.8793103448276, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI48994885, Length=481, Percent_Identity=22.4532224532225, Blast_Score=95, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6324401, Length=476, Percent_Identity=39.2857142857143, Blast_Score=362, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6320765, Length=476, Percent_Identity=39.2857142857143, Blast_Score=362, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR000669
- InterPro:   IPR013118
- InterPro:   IPR023027
- InterPro:   IPR013131
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01232 Mannitol_dh; PF08125 Mannitol_dh_C [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 54371; Mature: 54240

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS00974 MANNITOL_DHGENASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPMNTIASVTLPHHVHAPRYDRQQLQSRIVHFGFGAFHRAHQALLTDRVLNAQGGDWGI
CCCCHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
CEISLFSGDQLMSQLRAQNHLYTVLEKGADGNQAIIVGAVHECLNAKLDSLAAIIEKFCE
EEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCC
PQVAIVSLTITEKGYCIDPAIGALDTSNPRIIHDLQNPEEPHSAPGILVEALKRRRERGL
CCEEEEEEEEECCCCEECCCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHCCC
TPFTVLSCDNIPDNGHVVKNAVLGMAEKRSPELAGWIKEHVSFPGTMVDRIVPAATNESL
CCEEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHCCCCCCHHH
AEISQHLGVNDPCAISCEPFIQWVVEDNFVAGRPAWEVAGVQMVNDVLPWEEMKLRMLNG
HHHHHHCCCCCCCEECHHHHHHHHHCCCEECCCCCHHHHHHHHHHHCCCHHHHHHHHHCC
SHSFLAYLGYLSGFAHISDCMQDRAFRHAARTLMLDEQAPTLRIKDVDLTQYADKLIARF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEECCHHHHHHHHHHHHH
ANPALKHKTWQIAMDGSQKLPQRMLAGIRIHLGRETDWSLLALGVAGWMRYVSGVDDAGN
CCHHHHCCEEEEEECCHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCC
AIDVRDPLSDKIRELVAVSSSEQRVTALLSLREIFGDDLPDNPHFVQAIEQAWQQIAQFG
EEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
AHQALLNTLKI
HHHHHHHHHCC
>Mature Secondary Structure 
TPMNTIASVTLPHHVHAPRYDRQQLQSRIVHFGFGAFHRAHQALLTDRVLNAQGGDWGI
CCCHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
CEISLFSGDQLMSQLRAQNHLYTVLEKGADGNQAIIVGAVHECLNAKLDSLAAIIEKFCE
EEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCC
PQVAIVSLTITEKGYCIDPAIGALDTSNPRIIHDLQNPEEPHSAPGILVEALKRRRERGL
CCEEEEEEEEECCCCEECCCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHCCC
TPFTVLSCDNIPDNGHVVKNAVLGMAEKRSPELAGWIKEHVSFPGTMVDRIVPAATNESL
CCEEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHCCCCCCHHH
AEISQHLGVNDPCAISCEPFIQWVVEDNFVAGRPAWEVAGVQMVNDVLPWEEMKLRMLNG
HHHHHHCCCCCCCEECHHHHHHHHHCCCEECCCCCHHHHHHHHHHHCCCHHHHHHHHHCC
SHSFLAYLGYLSGFAHISDCMQDRAFRHAARTLMLDEQAPTLRIKDVDLTQYADKLIARF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEECCHHHHHHHHHHHHH
ANPALKHKTWQIAMDGSQKLPQRMLAGIRIHLGRETDWSLLALGVAGWMRYVSGVDDAGN
CCHHHHCCEEEEEECCHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCC
AIDVRDPLSDKIRELVAVSSSEQRVTALLSLREIFGDDLPDNPHFVQAIEQAWQQIAQFG
EEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
AHQALLNTLKI
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]