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The map label for this gene is yeiL [H]

Identifier: 91211450

GI number: 91211450

Start: 2395336

End: 2396034

Strand: Direct

Name: yeiL [H]

Synonym: UTI89_C2437

Alternate gene names: 91211450

Gene position: 2395336-2396034 (Clockwise)

Preceding gene: 91211448

Following gene: 91211454

Centisome position: 47.29

GC content: 43.35

Gene sequence:

>699_bases
GTGAAAGAAATCCACAATAATGATCTTAAGCAGCAATTGATGAGTGAATCTGCGTTTAAGGATTGCTTTTCAACGGATGT
TTCAGCCGATACGCGGCTGTTTCATTTTTTAGCGCGTGACTACATTGTGCAGGAAGGGCAACAGCCGTCCTGGCTGTTTT
ACCTGACGCGAGGCCGCGCCAGGCTTTACGTCACGCTTGCTAATGGTCGCGTGTCGCTAATCGATTTCTTTGCCGCGCCC
TGTTTTATTGGCGAGATTGAGTTAATCGACAAAGACCATGAACCGCGTGCAGTGCAGGCTATTGAAGAGTGTTGGTGCCT
TGCGCTCCCTATGAAGCATTACCGCCCGTTGTTATTAAACGACACGCTATTTTTACGAAAACTCTGCGTCACCTTAAGTC
ATAAAAATTATCGTAATATTGTTTCTTTAACTCAGAATCAATCATTTCCGTTAGTGAATCGCCTGGCAGCTTTTATATTA
CTCTCGCAGGAAGGTGATCTTTATCACGAAAAGCATACGCAAGCGGCAGAGTATTTAGGCGTTTCTTATCGACATCTTTT
ATATGTTCTTGCGCAATTCATTAATGACGGTTTATTAATTAAAAGCAAGAAAGGGTATCTCATTAAAAACAGAAAGCAGT
TGTCAGGACTGGCGCTGAAGATGTACCCGGAGAATAAATTCTCCGGGATGATGCAGTAA

Upstream 100 bases:

>100_bases
ATTGTTTCTACAGCAAAGAAAATTCGACCTGGCCGATGATTGAATCTTAACAACAGCGTACGTATGCTAAATATGAGAAA
TCTCATAGCGGATAAACATC

Downstream 100 bases:

>100_bases
AAATTATTGGCAATAGTGCGATTGCCGGATGCAACGCTTAATAAGGCGTACATCCGGCAATGAAACTCAAGCTAAACCAA
TAAAGAACCCGGCAATGGTC

Product: DNA-binding transcriptional activator YeiL

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MKEIHNNDLKQQLMSESAFKDCFSTDVSADTRLFHFLARDYIVQEGQQPSWLFYLTRGRARLYVTLANGRVSLIDFFAAP
CFIGEIELIDKDHEPRAVQAIEECWCLALPMKHYRPLLLNDTLFLRKLCVTLSHKNYRNIVSLTQNQSFPLVNRLAAFIL
LSQEGDLYHEKHTQAAEYLGVSYRHLLYVLAQFINDGLLIKSKKGYLIKNRKQLSGLALKMYPENKFSGMMQ

Sequences:

>Translated_232_residues
MKEIHNNDLKQQLMSESAFKDCFSTDVSADTRLFHFLARDYIVQEGQQPSWLFYLTRGRARLYVTLANGRVSLIDFFAAP
CFIGEIELIDKDHEPRAVQAIEECWCLALPMKHYRPLLLNDTLFLRKLCVTLSHKNYRNIVSLTQNQSFPLVNRLAAFIL
LSQEGDLYHEKHTQAAEYLGVSYRHLLYVLAQFINDGLLIKSKKGYLIKNRKQLSGLALKMYPENKFSGMMQ
>Mature_232_residues
MKEIHNNDLKQQLMSESAFKDCFSTDVSADTRLFHFLARDYIVQEGQQPSWLFYLTRGRARLYVTLANGRVSLIDFFAAP
CFIGEIELIDKDHEPRAVQAIEECWCLALPMKHYRPLLLNDTLFLRKLCVTLSHKNYRNIVSLTQNQSFPLVNRLAAFIL
LSQEGDLYHEKHTQAAEYLGVSYRHLLYVLAQFINDGLLIKSKKGYLIKNRKQLSGLALKMYPENKFSGMMQ

Specific function: Transcription regulator involved in mid-term, stationary-phase viability under nitrogen starvation. Might control expression of the salvage pathways or in some other way repress the recycling of nucleobases to nucleic acids and enhance their use as genera

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788487, Length=219, Percent_Identity=97.7168949771689, Blast_Score=445, Evalue=1e-126,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR012318
- InterPro:   IPR014710 [H]

Pfam domain/function: PF00027 cNMP_binding [H]

EC number: NA

Molecular weight: Translated: 26914; Mature: 26914

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEIHNNDLKQQLMSESAFKDCFSTDVSADTRLFHFLARDYIVQEGQQPSWLFYLTRGRA
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCE
RLYVTLANGRVSLIDFFAAPCFIGEIELIDKDHEPRAVQAIEECWCLALPMKHYRPLLLN
EEEEEEECCCCHHHHHHHCCHHCCEEEEECCCCCCHHHHHHHHHHHHHCCHHHCCCEEEC
DTLFLRKLCVTLSHKNYRNIVSLTQNQSFPLVNRLAAFILLSQEGDLYHEKHTQAAEYLG
CHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHEECCCCCCHHHHHHHHHHHHC
VSYRHLLYVLAQFINDGLLIKSKKGYLIKNRKQLSGLALKMYPENKFSGMMQ
CHHHHHHHHHHHHHCCCEEEECCCCCEEECCHHHCCEEEEECCCCCCCCCCC
>Mature Secondary Structure
MKEIHNNDLKQQLMSESAFKDCFSTDVSADTRLFHFLARDYIVQEGQQPSWLFYLTRGRA
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCE
RLYVTLANGRVSLIDFFAAPCFIGEIELIDKDHEPRAVQAIEECWCLALPMKHYRPLLLN
EEEEEEECCCCHHHHHHHCCHHCCEEEEECCCCCCHHHHHHHHHHHHHCCHHHCCCEEEC
DTLFLRKLCVTLSHKNYRNIVSLTQNQSFPLVNRLAAFILLSQEGDLYHEKHTQAAEYLG
CHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHEECCCCCCHHHHHHHHHHHHC
VSYRHLLYVLAQFINDGLLIKSKKGYLIKNRKQLSGLALKMYPENKFSGMMQ
CHHHHHHHHHHHHHCCCEEEECCCCCEEECCHHHCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]