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The map label for this gene is yeaJ [H]

Identifier: 91211003

GI number: 91211003

Start: 1904112

End: 1905782

Strand: Direct

Name: yeaJ [H]

Synonym: UTI89_C1982

Alternate gene names: 91211003

Gene position: 1904112-1905782 (Clockwise)

Preceding gene: 91211002

Following gene: 91211004

Centisome position: 37.59

GC content: 45.48

Gene sequence:

>1671_bases
GTGCAAAAATATTCAGAGCCATGCTTTTTGCGTGGCTTTTGCATACAATTTATTACTATTACCCCTAAATTTCCCCTCCC
CAGCGGCGCAGAGATGAGTATAATTAGCGCCCCTGTGCCAGGCCGCAATCGAACTTTATCTGGTTTTCTCGTTTCACTAA
CCGAAGGAGTGCCATTTATCATGAAATTGCACCATAGAATGCTCCGGCATTTTATCGCCGCAAGTGTCATTGTGCTGACA
TCTTCCTTCCTTATTTTTGAACTTGTCGCCAGTGACAGAGCAATGAGTGCCTATCTGCGCTATATCGTGCAGAGAGCAGA
CTCCTCCTTTCTTTATGATAAGTATCAGAATCAGAGTATTGCCGCGCATGTGATGCGCGCTCTCGCTGCTGAGCAGTCGG
AAGTGTCGCCAGAACAGCGGCGCGCCATCTGCGAGGCTTTTGAGTCTGCCAATAATACCCATGGCTTAAACCTGACTGCC
CATAAATACCCTGGCTTACGCGGCACACTACAAACCGCATCCACTGACTGTGACACAATTGTGGAAGCTGCTGCACTATT
ACCCGCTTTTGATCAGGCAGTGGAAGGCAACCGCCACCAGGATGATTACGGTTCAGGTCTTGGGATGGCCGAAGAGAAAT
TTCACTATTATCTCGATCTCAATGACCGCTATGTCTATTTTTATGAGCCGGTTAATGTTGAGTACTTTGCGATGAATAAC
TGGTCCTTCCTGCAGTCAGGAAGTATTGGCATCGATCGCAAAGATATTGAAAAGGTATTTACCGGGCGTACCGTATTATC
GAGCATTTACCAGGATCAGCGTACTAAACAGAACGTGATGAGTTTACTGACGCCGGTATATGTCGCAGGGCAGCTAAAAG
GGATTGTGCTGCTGGATATTAACAAAAACAATCTGCGGAATATCTTTTACACTCATGACCGCCCTCTCCTCTGGCGTTTT
CTCAATGTCACGCTAACTGATACAGATTCGGGGCGCGACATTATCATCAACCAGAGCGAAGATAATCTGTTCCAGTATGT
CAGTTACGTCCATGACTTACCGGGCGGCATTCGTGTCTCGTTATCCATTGATATTCTTTACTTTATCACGTCTTCGTGGA
AAAGCGTTCTGTTCTGGATTTTGACGGCGTTAATTTTGCTGAATATGGTGCGGATGCACTTCCGTTTATACCAAAATGTG
TCGCGAGAAAATATTAGTGATGCGATGACTGGACTGTATAATCGCAAAATTTTAACCCCTGAACTGGAGCAGCGGTTGCA
GAAACTGGTGCAATCCGGTTCTTCGGTGATGTTTATTGCAATTGACATGGACAAGTTAAAGCAAATAAATGACACCCTTG
GTCATCAGGAGGGGGATTTAGCGATTACGTTATTAGCTCAGGCGATTAAACAATCGATTCGTAAAAGTGATTATGCCATC
CGACTCGGTGGCGATGAATTCTGCATCATTCTTGTCGATTCGACGCCGCAAATTGCAGCACAACTGCCTGAACGTATCGA
AAAACGTCTGCAACATATCGCGCCGCAGAAAGAGATCGGCTTCTCTTCCGGTATTTACGCGATGAAAGAAAACGATACGT
TACATGATGCGTATAAAGCTTCCGATGAGCGTTTATATGTCAATAAGCAGAACAAAAACAGCCGTTCATGA

Upstream 100 bases:

>100_bases
TGACACGCATAATATCTCGCTTGTCATGACGGAAGCAGATAAAGCCTTACGCGAAGCGAAAAGCGAAGGGGGCAACAAAG
TGATTATTCATCATATTTAA

Downstream 100 bases:

>100_bases
TAATCTTCTGTGGTTGTTTGCTTGTAATCTCAGGAGCATGAAATGACTGAAATGGCTAAAGGAAGCGTGACGCATCAGCG
GTTAATCGCTTTATTATCGC

Product: hypothetical protein

Products: NA

Alternate protein names: DGC [H]

Number of amino acids: Translated: 556; Mature: 556

Protein sequence:

>556_residues
MQKYSEPCFLRGFCIQFITITPKFPLPSGAEMSIISAPVPGRNRTLSGFLVSLTEGVPFIMKLHHRMLRHFIAASVIVLT
SSFLIFELVASDRAMSAYLRYIVQRADSSFLYDKYQNQSIAAHVMRALAAEQSEVSPEQRRAICEAFESANNTHGLNLTA
HKYPGLRGTLQTASTDCDTIVEAAALLPAFDQAVEGNRHQDDYGSGLGMAEEKFHYYLDLNDRYVYFYEPVNVEYFAMNN
WSFLQSGSIGIDRKDIEKVFTGRTVLSSIYQDQRTKQNVMSLLTPVYVAGQLKGIVLLDINKNNLRNIFYTHDRPLLWRF
LNVTLTDTDSGRDIIINQSEDNLFQYVSYVHDLPGGIRVSLSIDILYFITSSWKSVLFWILTALILLNMVRMHFRLYQNV
SRENISDAMTGLYNRKILTPELEQRLQKLVQSGSSVMFIAIDMDKLKQINDTLGHQEGDLAITLLAQAIKQSIRKSDYAI
RLGGDEFCIILVDSTPQIAAQLPERIEKRLQHIAPQKEIGFSSGIYAMKENDTLHDAYKASDERLYVNKQNKNSRS

Sequences:

>Translated_556_residues
MQKYSEPCFLRGFCIQFITITPKFPLPSGAEMSIISAPVPGRNRTLSGFLVSLTEGVPFIMKLHHRMLRHFIAASVIVLT
SSFLIFELVASDRAMSAYLRYIVQRADSSFLYDKYQNQSIAAHVMRALAAEQSEVSPEQRRAICEAFESANNTHGLNLTA
HKYPGLRGTLQTASTDCDTIVEAAALLPAFDQAVEGNRHQDDYGSGLGMAEEKFHYYLDLNDRYVYFYEPVNVEYFAMNN
WSFLQSGSIGIDRKDIEKVFTGRTVLSSIYQDQRTKQNVMSLLTPVYVAGQLKGIVLLDINKNNLRNIFYTHDRPLLWRF
LNVTLTDTDSGRDIIINQSEDNLFQYVSYVHDLPGGIRVSLSIDILYFITSSWKSVLFWILTALILLNMVRMHFRLYQNV
SRENISDAMTGLYNRKILTPELEQRLQKLVQSGSSVMFIAIDMDKLKQINDTLGHQEGDLAITLLAQAIKQSIRKSDYAI
RLGGDEFCIILVDSTPQIAAQLPERIEKRLQHIAPQKEIGFSSGIYAMKENDTLHDAYKASDERLYVNKQNKNSRS
>Mature_556_residues
MQKYSEPCFLRGFCIQFITITPKFPLPSGAEMSIISAPVPGRNRTLSGFLVSLTEGVPFIMKLHHRMLRHFIAASVIVLT
SSFLIFELVASDRAMSAYLRYIVQRADSSFLYDKYQNQSIAAHVMRALAAEQSEVSPEQRRAICEAFESANNTHGLNLTA
HKYPGLRGTLQTASTDCDTIVEAAALLPAFDQAVEGNRHQDDYGSGLGMAEEKFHYYLDLNDRYVYFYEPVNVEYFAMNN
WSFLQSGSIGIDRKDIEKVFTGRTVLSSIYQDQRTKQNVMSLLTPVYVAGQLKGIVLLDINKNNLRNIFYTHDRPLLWRF
LNVTLTDTDSGRDIIINQSEDNLFQYVSYVHDLPGGIRVSLSIDILYFITSSWKSVLFWILTALILLNMVRMHFRLYQNV
SRENISDAMTGLYNRKILTPELEQRLQKLVQSGSSVMFIAIDMDKLKQINDTLGHQEGDLAITLLAQAIKQSIRKSDYAI
RLGGDEFCIILVDSTPQIAAQLPERIEKRLQHIAPQKEIGFSSGIYAMKENDTLHDAYKASDERLYVNKQNKNSRS

Specific function: Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI87081974, Length=496, Percent_Identity=99.7983870967742, Blast_Score=1025, Evalue=0.0,
Organism=Escherichia coli, GI145693134, Length=169, Percent_Identity=33.1360946745562, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87082007, Length=220, Percent_Identity=30, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1786584, Length=155, Percent_Identity=29.6774193548387, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1787262, Length=228, Percent_Identity=27.1929824561404, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI87081881, Length=163, Percent_Identity=28.8343558282209, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1788381, Length=169, Percent_Identity=28.9940828402367, Blast_Score=66, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160 [H]

Pfam domain/function: PF00990 GGDEF [H]

EC number: =2.7.7.65 [H]

Molecular weight: Translated: 63205; Mature: 63205

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKYSEPCFLRGFCIQFITITPKFPLPSGAEMSIISAPVPGRNRTLSGFLVSLTEGVPFI
CCCCCCCHHHHHEEEEEEEECCCCCCCCCCCEEEEECCCCCCCCCHHHHHEEHHCCCHHH
MKLHHRMLRHFIAASVIVLTSSFLIFELVASDRAMSAYLRYIVQRADSSFLYDKYQNQSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHCCCHH
AAHVMRALAAEQSEVSPEQRRAICEAFESANNTHGLNLTAHKYPGLRGTLQTASTDCDTI
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHH
VEAAALLPAFDQAVEGNRHQDDYGSGLGMAEEKFHYYLDLNDRYVYFYEPVNVEYFAMNN
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCEEEEEECCCEEEEEECC
WSFLQSGSIGIDRKDIEKVFTGRTVLSSIYQDQRTKQNVMSLLTPVYVAGQLKGIVLLDI
CCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
NKNNLRNIFYTHDRPLLWRFLNVTLTDTDSGRDIIINQSEDNLFQYVSYVHDLPGGIRVS
CCCCCCEEEEECCCHHEEEEEEEEEEECCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEE
LSIDILYFITSSWKSVLFWILTALILLNMVRMHFRLYQNVSRENISDAMTGLYNRKILTP
EEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCH
ELEQRLQKLVQSGSSVMFIAIDMDKLKQINDTLGHQEGDLAITLLAQAIKQSIRKSDYAI
HHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEE
RLGGDEFCIILVDSTPQIAAQLPERIEKRLQHIAPQKEIGFSSGIYAMKENDTLHDAYKA
EECCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCHHHCCCCCCEEEEECCCCHHHHHCC
SDERLYVNKQNKNSRS
CCCEEEEECCCCCCCC
>Mature Secondary Structure
MQKYSEPCFLRGFCIQFITITPKFPLPSGAEMSIISAPVPGRNRTLSGFLVSLTEGVPFI
CCCCCCCHHHHHEEEEEEEECCCCCCCCCCCEEEEECCCCCCCCCHHHHHEEHHCCCHHH
MKLHHRMLRHFIAASVIVLTSSFLIFELVASDRAMSAYLRYIVQRADSSFLYDKYQNQSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHCCCHH
AAHVMRALAAEQSEVSPEQRRAICEAFESANNTHGLNLTAHKYPGLRGTLQTASTDCDTI
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHH
VEAAALLPAFDQAVEGNRHQDDYGSGLGMAEEKFHYYLDLNDRYVYFYEPVNVEYFAMNN
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCEEEEEECCCEEEEEECC
WSFLQSGSIGIDRKDIEKVFTGRTVLSSIYQDQRTKQNVMSLLTPVYVAGQLKGIVLLDI
CCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
NKNNLRNIFYTHDRPLLWRFLNVTLTDTDSGRDIIINQSEDNLFQYVSYVHDLPGGIRVS
CCCCCCEEEEECCCHHEEEEEEEEEEECCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEE
LSIDILYFITSSWKSVLFWILTALILLNMVRMHFRLYQNVSRENISDAMTGLYNRKILTP
EEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCH
ELEQRLQKLVQSGSSVMFIAIDMDKLKQINDTLGHQEGDLAITLLAQAIKQSIRKSDYAI
HHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEE
RLGGDEFCIILVDSTPQIAAQLPERIEKRLQHIAPQKEIGFSSGIYAMKENDTLHDAYKA
EECCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCHHHCCCCCCEEEEECCCCHHHHHCC
SDERLYVNKQNKNSRS
CCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]