| Definition | Escherichia coli UTI89 chromosome, complete genome. |
|---|---|
| Accession | NC_007946 |
| Length | 5,065,741 |
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The map label for this gene is malX [H]
Identifier: 91210832
GI number: 91210832
Start: 1739407
End: 1741203
Strand: Direct
Name: malX [H]
Synonym: UTI89_C1809
Alternate gene names: 91210832
Gene position: 1739407-1741203 (Clockwise)
Preceding gene: 91210825
Following gene: 91210833
Centisome position: 34.34
GC content: 50.36
Gene sequence:
>1797_bases ATGAATGGTTATTTTTTTGGCGGTAGCCATGCAGATGACCTACTCCCTGATTATGTGACAGATAAAACGTTTTACCTTTT ATTTATCTTATACCCGCTATTATCGTTGTGTAATGTGATTTATGCCTCACTAAAATTTGATAAAACGTTTTATCTTCTCG CGCAATTTATTGAATCCAGATTGTTCTCTACGAGGAGTCGTTTTATGACGGCGAAAACAGCACCGAAAGTCACGCTGTGG GAGTTCTTCCAGCAGTTAGGCAAAACCTTCATGTTACCCGTGGCATTATTGTCGTTCTGCGGCATTATGCTCGGCATTGG TAGTTCTCTTAGCAGCCATGATGTCATCACCCTGATCCCGGTCCTGGGCAACCCCGTGTTGCAGGCTATCTTTACCTGGA TGAGTAAGATTGGCTCGTTTGCTTTTAGTTTCCTGCCAGTCATGTTCTGTATCGCCATCCCGCTGGGTCTGGCACGCGAA AACAAAGGCGTAGCGGCATTCGCTGGCTTCGTCGGTTATGCGGTAATGAACCTCGCGGTAAACTTCTGGTTGACCAATAA AGGCATTCTGCCAACCACGGACGCCGCAGTTCTGAAAGCCAATAACATCCAGAGCATTCTTGGGATCCAGTCGATCGACA CCGGGATCCTCGGTGCGGTGATCGCCGGTATTATCGTCTGGATGCTGCATGAGCGATTCCATAATATCCGCCTGCCGGAT GCGCTGGCATTCTTCGGCGGTACGCGCTTCGTACCAATCATCTCCTCGCTAGTGATGGGTCTTGTCGGCCTGGTGATTCC ATTAGTCTGGCCGATTTTCGCCATGGGTATTAGCGGCTTAGGCCATATGATCAACAGCGCGGGAGATTTCGGACCGATGC TGTTTGGTACCGGTGAACGTCTGCTGTTGCCGTTTGGTCTGCATCACATTCTGGTGGCATTAATTCGCTTTACCGACGCA GGCGGCACGCAGGAAGTCTGCGGTCAAACCGTCAGCGGTGCACTGACCATCTTCCAGGCGCAATTGAGTTGCCCAACCAC TCACGGTTTTTCTGAAAGCGCCACGCGTTTCCTTTCGCAAGGTAAAATGCCTGCGTTTCTCGGCGGTCTGCCAGGTGCAG CGTTAGCTATGTATCACTGTGCGCGCCCGGAAAATCGCCATAAAATTAAAGGTCTGCTGATTTCTGGCCTGATCGCCTGT GTCGTTGGCGGCACGACCGAACCGCTGGAATTCCTGTTCCTGTTCGTAGCGCCAGTTCTGTATGTCATCCACGCGCTGTT AACCGGCCTCGGCTTCACTGTCATGTCTGTGCTCGGCGTCACCATCGGTAATACCGACGGCAATATCATCGACTTTGTGG TGTTCGGTATTTTGCATGGTCTGTCAACCAAGTGGTACATGGTGCCAGTAGTGGCGGCAATCTGGTTTGTCGTTTACTAC ATCATCTTCCGTTTCGCTATCACCCGCTTCAATCTCAAAACCCCGGGGCGCGATAGTGAAGTTGCCAGTTCAATCGAAAA AGCCGTTGCCGGTGCGCCGGGTAAATCAGGTTACAACGTTCCGGCAATCCTCGAAGCCTTAGGCGGTGCCGACAATATTG TCAGCCTCGATAACTGCATTACGCGTCTGCGTTTGTCTGTAAAAGATATGTCGCTTGTTAATGTGCAGGCACTGAAGGAC AATCGGGCAATTGGCGTAGTACAACTTAATCAACATAACCTGCAGGTTGTTATCGGGCCACAAGTTCAGTCAGTAAAAGA TGAAATGGCCGGTCTGATGCATACTGTCCAGGCATAA
Upstream 100 bases:
>100_bases CGGCGTTAACGCGTTCTCCTGTGGCGGTAGAGATTCGCCCTTTGCCACTAAGCACCAGCGAAACGGTACTTACCGACACG CCCGCAGCCAGCGCAACATC
Downstream 100 bases:
>100_bases GGATAAGATATGTTCGATTTTTCAAAGGTCGTGGATCGTCATGGCACATGGTGTACGCAGTGGGATTATGTCGCTGACCG TTTCGGCACTGCTGACCTGT
Product: bifunctional PTS system maltose and glucose-specific transporter subunits IICB
Products: NA
Alternate protein names: Maltose and glucose permease IIC component; PTS system maltose- and glucose-specific EIIC component; Maltose- and glucose-specific phosphotransferase enzyme IIB component; PTS system maltose- and glucose-specific EIIB component [H]
Number of amino acids: Translated: 598; Mature: 598
Protein sequence:
>598_residues MNGYFFGGSHADDLLPDYVTDKTFYLLFILYPLLSLCNVIYASLKFDKTFYLLAQFIESRLFSTRSRFMTAKTAPKVTLW EFFQQLGKTFMLPVALLSFCGIMLGIGSSLSSHDVITLIPVLGNPVLQAIFTWMSKIGSFAFSFLPVMFCIAIPLGLARE NKGVAAFAGFVGYAVMNLAVNFWLTNKGILPTTDAAVLKANNIQSILGIQSIDTGILGAVIAGIIVWMLHERFHNIRLPD ALAFFGGTRFVPIISSLVMGLVGLVIPLVWPIFAMGISGLGHMINSAGDFGPMLFGTGERLLLPFGLHHILVALIRFTDA GGTQEVCGQTVSGALTIFQAQLSCPTTHGFSESATRFLSQGKMPAFLGGLPGAALAMYHCARPENRHKIKGLLISGLIAC VVGGTTEPLEFLFLFVAPVLYVIHALLTGLGFTVMSVLGVTIGNTDGNIIDFVVFGILHGLSTKWYMVPVVAAIWFVVYY IIFRFAITRFNLKTPGRDSEVASSIEKAVAGAPGKSGYNVPAILEALGGADNIVSLDNCITRLRLSVKDMSLVNVQALKD NRAIGVVQLNQHNLQVVIGPQVQSVKDEMAGLMHTVQA
Sequences:
>Translated_598_residues MNGYFFGGSHADDLLPDYVTDKTFYLLFILYPLLSLCNVIYASLKFDKTFYLLAQFIESRLFSTRSRFMTAKTAPKVTLW EFFQQLGKTFMLPVALLSFCGIMLGIGSSLSSHDVITLIPVLGNPVLQAIFTWMSKIGSFAFSFLPVMFCIAIPLGLARE NKGVAAFAGFVGYAVMNLAVNFWLTNKGILPTTDAAVLKANNIQSILGIQSIDTGILGAVIAGIIVWMLHERFHNIRLPD ALAFFGGTRFVPIISSLVMGLVGLVIPLVWPIFAMGISGLGHMINSAGDFGPMLFGTGERLLLPFGLHHILVALIRFTDA GGTQEVCGQTVSGALTIFQAQLSCPTTHGFSESATRFLSQGKMPAFLGGLPGAALAMYHCARPENRHKIKGLLISGLIAC VVGGTTEPLEFLFLFVAPVLYVIHALLTGLGFTVMSVLGVTIGNTDGNIIDFVVFGILHGLSTKWYMVPVVAAIWFVVYY IIFRFAITRFNLKTPGRDSEVASSIEKAVAGAPGKSGYNVPAILEALGGADNIVSLDNCITRLRLSVKDMSLVNVQALKD NRAIGVVQLNQHNLQVVIGPQVQSVKDEMAGLMHTVQA >Mature_598_residues MNGYFFGGSHADDLLPDYVTDKTFYLLFILYPLLSLCNVIYASLKFDKTFYLLAQFIESRLFSTRSRFMTAKTAPKVTLW EFFQQLGKTFMLPVALLSFCGIMLGIGSSLSSHDVITLIPVLGNPVLQAIFTWMSKIGSFAFSFLPVMFCIAIPLGLARE NKGVAAFAGFVGYAVMNLAVNFWLTNKGILPTTDAAVLKANNIQSILGIQSIDTGILGAVIAGIIVWMLHERFHNIRLPD ALAFFGGTRFVPIISSLVMGLVGLVIPLVWPIFAMGISGLGHMINSAGDFGPMLFGTGERLLLPFGLHHILVALIRFTDA GGTQEVCGQTVSGALTIFQAQLSCPTTHGFSESATRFLSQGKMPAFLGGLPGAALAMYHCARPENRHKIKGLLISGLIAC VVGGTTEPLEFLFLFVAPVLYVIHALLTGLGFTVMSVLGVTIGNTDGNIIDFVVFGILHGLSTKWYMVPVVAAIWFVVYY IIFRFAITRFNLKTPGRDSEVASSIEKAVAGAPGKSGYNVPAILEALGGADNIVSLDNCITRLRLSVKDMSLVNVQALKD NRAIGVVQLNQHNLQVVIGPQVQSVKDEMAGLMHTVQA
Specific function: MalX encodes a phosphotransferase system enzyme II that can recognize glucose and maltose as substrates even though these sugars may not represent the natural substrates of the system [H]
COG id: COG1263
COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific
Gene ontology:
Cell location: Cell inner membrane; Multi-pass membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PTS EIIC type-1 domain [H]
Homologues:
Organism=Escherichia coli, GI1787908, Length=530, Percent_Identity=99.622641509434, Blast_Score=1066, Evalue=0.0, Organism=Escherichia coli, GI1787343, Length=516, Percent_Identity=37.015503875969, Blast_Score=268, Evalue=6e-73, Organism=Escherichia coli, GI1786894, Length=510, Percent_Identity=33.921568627451, Blast_Score=218, Evalue=1e-57,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR018113 - InterPro: IPR004719 - InterPro: IPR001996 - InterPro: IPR003352 - InterPro: IPR013013 - InterPro: IPR011535 - InterPro: IPR011301 [H]
Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]
EC number: =2.7.1.69 [H]
Molecular weight: Translated: 64618; Mature: 64618
Theoretical pI: Translated: 8.54; Mature: 8.54
Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1 ; PS00284 SERPIN
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.3 %Cys (Translated Protein) 3.2 %Met (Translated Protein) 4.5 %Cys+Met (Translated Protein) 1.3 %Cys (Mature Protein) 3.2 %Met (Mature Protein) 4.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNGYFFGGSHADDLLPDYVTDKTFYLLFILYPLLSLCNVIYASLKFDKTFYLLAQFIESR CCCEECCCCCCHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH LFSTRSRFMTAKTAPKVTLWEFFQQLGKTFMLPVALLSFCGIMLGIGSSLSSHDVITLIP HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEH VLGNPVLQAIFTWMSKIGSFAFSFLPVMFCIAIPLGLARENKGVAAFAGFVGYAVMNLAV HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH NFWLTNKGILPTTDAAVLKANNIQSILGIQSIDTGILGAVIAGIIVWMLHERFHNIRLPD HHEEECCCCCCCCCHHHHECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH ALAFFGGTRFVPIISSLVMGLVGLVIPLVWPIFAMGISGLGHMINSAGDFGPMLFGTGER HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCC LLLPFGLHHILVALIRFTDAGGTQEVCGQTVSGALTIFQAQLSCPTTHGFSESATRFLSQ EEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHC GKMPAFLGGLPGAALAMYHCARPENRHKIKGLLISGLIACVVGGTTEPLEFLFLFVAPVL CCCCHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH YVIHALLTGLGFTVMSVLGVTIGNTDGNIIDFVVFGILHGLSTKWYMVPVVAAIWFVVYY HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH IIFRFAITRFNLKTPGRDSEVASSIEKAVAGAPGKSGYNVPAILEALGGADNIVSLDNCI HHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCEEHHHHHH TRLRLSVKDMSLVNVQALKDNRAIGVVQLNQHNLQVVIGPQVQSVKDEMAGLMHTVQA HHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHCC >Mature Secondary Structure MNGYFFGGSHADDLLPDYVTDKTFYLLFILYPLLSLCNVIYASLKFDKTFYLLAQFIESR CCCEECCCCCCHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH LFSTRSRFMTAKTAPKVTLWEFFQQLGKTFMLPVALLSFCGIMLGIGSSLSSHDVITLIP HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEH VLGNPVLQAIFTWMSKIGSFAFSFLPVMFCIAIPLGLARENKGVAAFAGFVGYAVMNLAV HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH NFWLTNKGILPTTDAAVLKANNIQSILGIQSIDTGILGAVIAGIIVWMLHERFHNIRLPD HHEEECCCCCCCCCHHHHECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH ALAFFGGTRFVPIISSLVMGLVGLVIPLVWPIFAMGISGLGHMINSAGDFGPMLFGTGER HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCC LLLPFGLHHILVALIRFTDAGGTQEVCGQTVSGALTIFQAQLSCPTTHGFSESATRFLSQ EEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHC GKMPAFLGGLPGAALAMYHCARPENRHKIKGLLISGLIACVVGGTTEPLEFLFLFVAPVL CCCCHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH YVIHALLTGLGFTVMSVLGVTIGNTDGNIIDFVVFGILHGLSTKWYMVPVVAAIWFVVYY HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH IIFRFAITRFNLKTPGRDSEVASSIEKAVAGAPGKSGYNVPAILEALGGADNIVSLDNCI HHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCEEHHHHHH TRLRLSVKDMSLVNVQALKDNRAIGVVQLNQHNLQVVIGPQVQSVKDEMAGLMHTVQA HHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 1856179; 9097039; 9278503; 2670898 [H]