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The map label for this gene is mviN [H]

Identifier: 89898801

GI number: 89898801

Start: 1147585

End: 1148547

Strand: Direct

Name: mviN [H]

Synonym: CF0993

Alternate gene names: 89898801

Gene position: 1147585-1148547 (Clockwise)

Preceding gene: 89898797

Following gene: 89898803

Centisome position: 98.4

GC content: 39.98

Gene sequence:

>963_bases
ATGATCCCTGGCCGTCTTTTTTATTCATTAAAATGTCTTACTCCCTTAATACTTAATTTATCCATACCAGATAGAGATTT
TCGGAGCATTAAAATGCAGATATATCCGCCTCCCCAAGAACCTTTATTAGGCGCCCACACATCCACCTCAGGGGGTCTGC
AAAATGCCATCTACGAAGGTCAAGAAATCGGGGCTTCTACTATTCAAATGTTTACCGCCAATCAAAGACAATGGCGTAGA
CGTCCTCTTACCGACACCATGGTAAATTCTTTTAAACAAGCTCTTGAAGAAACCTCTTTATCTTATATTATGAGCCATGC
TGGCTACTTAATTAATCCTGGGGCACCTAACCCAGAAATCCTAGAAAAAAGTCGTATTTGCATACAGCAAGAGATTCAAG
ATTGTATATCTTTAGGAATCTCTTTTGTTAATTTCCATCCTGGTGCAGCTGTCAATGACACAAAGGAAGCTTGTTTAGAT
AGAATTGTTTCAAGTTTTTCTTTGGTTGAGCCTTTATTTGAAGACTCCCCTCCTCTTGTTGTCCTTTTTGAAACTACCGC
GGGTCAAGGAACCCTTGTCGGAAGTAATTTTGAAGAACTTGGCTATCTAATAGACAAACTTAAGCATAAAATCCCTGTAG
GAGTTTGCATAGATACATGTCATATCTTTGCTGCTGGTTATGATATTACCTCTCCAGACTCTTGGAAGCAAGTGCTCAGA
AATTTTGATGATCACGTTGGCTTATCATATTTAAGAGCTTTTCACCTTAACGACTCTATGTTTCCCCTAGGACAACACAA
GGATCGCCATGCGCCTATCGGAGAGGGAGATATAGGGATTGAAAGTTTTAAATTTCTTATGACCGATAAAGCCACGCGGA
TGATCCCTAAGTACCTAGAGACTCCTGGAGGCCCAGACTTATGGGCAAAAGAAATCAGTCTATTGCAAAGTTTTCAAAAG
TAA

Upstream 100 bases:

>100_bases
TCGGCCCCAAAATAAGCTGCCATAACAATTTCGCGCAGCATTCCTGTTACACGACTAAAAAAGGTTCCTGACAACAAATT
AAAAAGTGAGCTGGCTATAG

Downstream 100 bases:

>100_bases
GTGAAAGAAAAAAATTAGAAGCGCCAGCTAAAGGTAGGCGGCGCCTCTCTTTTTGGAAGAAAGAAATTTTATGTTCTGTG
AGACAAGAACTCACATACCA

Product: endonuclease IV

Products: NA

Alternate protein names: Endodeoxyribonuclease IV; Endonuclease IV [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MIPGRLFYSLKCLTPLILNLSIPDRDFRSIKMQIYPPPQEPLLGAHTSTSGGLQNAIYEGQEIGASTIQMFTANQRQWRR
RPLTDTMVNSFKQALEETSLSYIMSHAGYLINPGAPNPEILEKSRICIQQEIQDCISLGISFVNFHPGAAVNDTKEACLD
RIVSSFSLVEPLFEDSPPLVVLFETTAGQGTLVGSNFEELGYLIDKLKHKIPVGVCIDTCHIFAAGYDITSPDSWKQVLR
NFDDHVGLSYLRAFHLNDSMFPLGQHKDRHAPIGEGDIGIESFKFLMTDKATRMIPKYLETPGGPDLWAKEISLLQSFQK

Sequences:

>Translated_320_residues
MIPGRLFYSLKCLTPLILNLSIPDRDFRSIKMQIYPPPQEPLLGAHTSTSGGLQNAIYEGQEIGASTIQMFTANQRQWRR
RPLTDTMVNSFKQALEETSLSYIMSHAGYLINPGAPNPEILEKSRICIQQEIQDCISLGISFVNFHPGAAVNDTKEACLD
RIVSSFSLVEPLFEDSPPLVVLFETTAGQGTLVGSNFEELGYLIDKLKHKIPVGVCIDTCHIFAAGYDITSPDSWKQVLR
NFDDHVGLSYLRAFHLNDSMFPLGQHKDRHAPIGEGDIGIESFKFLMTDKATRMIPKYLETPGGPDLWAKEISLLQSFQK
>Mature_320_residues
MIPGRLFYSLKCLTPLILNLSIPDRDFRSIKMQIYPPPQEPLLGAHTSTSGGLQNAIYEGQEIGASTIQMFTANQRQWRR
RPLTDTMVNSFKQALEETSLSYIMSHAGYLINPGAPNPEILEKSRICIQQEIQDCISLGISFVNFHPGAAVNDTKEACLD
RIVSSFSLVEPLFEDSPPLVVLFETTAGQGTLVGSNFEELGYLIDKLKHKIPVGVCIDTCHIFAAGYDITSPDSWKQVLR
NFDDHVGLSYLRAFHLNDSMFPLGQHKDRHAPIGEGDIGIESFKFLMTDKATRMIPKYLETPGGPDLWAKEISLLQSFQK

Specific function: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by ble

COG id: COG0648

COG function: function code L; Endonuclease IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AP endonuclease 2 family [H]

Homologues:

Organism=Escherichia coli, GI1788483, Length=280, Percent_Identity=43.5714285714286, Blast_Score=233, Evalue=1e-62,
Organism=Caenorhabditis elegans, GI17531193, Length=266, Percent_Identity=43.984962406015, Blast_Score=239, Evalue=1e-63,
Organism=Saccharomyces cerevisiae, GI6322735, Length=278, Percent_Identity=33.0935251798561, Blast_Score=172, Evalue=5e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018246
- InterPro:   IPR001719
- InterPro:   IPR013022
- InterPro:   IPR012307 [H]

Pfam domain/function: PF01261 AP_endonuc_2 [H]

EC number: =3.1.21.2 [H]

Molecular weight: Translated: 35749; Mature: 35749

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: PS00729 AP_NUCLEASE_F2_1 ; PS00730 AP_NUCLEASE_F2_2 ; PS00731 AP_NUCLEASE_F2_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPGRLFYSLKCLTPLILNLSIPDRDFRSIKMQIYPPPQEPLLGAHTSTSGGLQNAIYEG
CCCCHHHHHHHHHHHHHEECCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHCC
QEIGASTIQMFTANQRQWRRRPLTDTMVNSFKQALEETSLSYIMSHAGYLINPGAPNPEI
HHCCHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCHHH
LEKSRICIQQEIQDCISLGISFVNFHPGAAVNDTKEACLDRIVSSFSLVEPLFEDSPPLV
HHHHHHHHHHHHHHHHHHCCHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEE
VLFETTAGQGTLVGSNFEELGYLIDKLKHKIPVGVCIDTCHIFAAGYDITSPDSWKQVLR
EEEECCCCCCEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHEECCCCCCCHHHHHHHH
NFDDHVGLSYLRAFHLNDSMFPLGQHKDRHAPIGEGDIGIESFKFLMTDKATRMIPKYLE
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
TPGGPDLWAKEISLLQSFQK
CCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIPGRLFYSLKCLTPLILNLSIPDRDFRSIKMQIYPPPQEPLLGAHTSTSGGLQNAIYEG
CCCCHHHHHHHHHHHHHEECCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHCC
QEIGASTIQMFTANQRQWRRRPLTDTMVNSFKQALEETSLSYIMSHAGYLINPGAPNPEI
HHCCHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCHHH
LEKSRICIQQEIQDCISLGISFVNFHPGAAVNDTKEACLDRIVSSFSLVEPLFEDSPPLV
HHHHHHHHHHHHHHHHHHCCHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEE
VLFETTAGQGTLVGSNFEELGYLIDKLKHKIPVGVCIDTCHIFAAGYDITSPDSWKQVLR
EEEECCCCCCEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHEECCCCCCCHHHHHHHH
NFDDHVGLSYLRAFHLNDSMFPLGQHKDRHAPIGEGDIGIESFKFLMTDKATRMIPKYLE
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
TPGGPDLWAKEISLLQSFQK
CCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA